DK0680470T3 - - Google Patents
Info
- Publication number
- DK0680470T3 DK0680470T3 DK94906446.3T DK94906446T DK0680470T3 DK 0680470 T3 DK0680470 T3 DK 0680470T3 DK 94906446 T DK94906446 T DK 94906446T DK 0680470 T3 DK0680470 T3 DK 0680470T3
- Authority
- DK
- Denmark
- Prior art keywords
- pct
- sec
- date
- tumors
- pub
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 102100033350 ATP-dependent translocase ABCB1 Human genes 0.000 abstract 1
- 206010059866 Drug resistance Diseases 0.000 abstract 1
- 108010047230 Member 1 Subfamily B ATP Binding Cassette Transporter Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 150000003053 piperidines Chemical class 0.000 abstract 1
- 230000005748 tumor development Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/16—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with acylated ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US656993A | 1993-01-21 | 1993-01-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0680470T3 true DK0680470T3 (fr) | 1997-04-28 |
Family
ID=21721516
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94906446.3T DK0680470T3 (fr) | 1993-01-21 | 1993-12-17 |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5648365A (fr) |
| EP (1) | EP0680470B1 (fr) |
| JP (1) | JP3398748B2 (fr) |
| KR (1) | KR100377280B1 (fr) |
| AT (1) | ATE150748T1 (fr) |
| AU (1) | AU679723B2 (fr) |
| CA (1) | CA2152794C (fr) |
| DE (1) | DE69309310T2 (fr) |
| DK (1) | DK0680470T3 (fr) |
| ES (1) | ES2102830T3 (fr) |
| FI (1) | FI112474B (fr) |
| GR (1) | GR3023188T3 (fr) |
| HU (1) | HUT72078A (fr) |
| IL (1) | IL108369A (fr) |
| MX (1) | MX9400563A (fr) |
| NO (1) | NO305166B1 (fr) |
| NZ (1) | NZ261414A (fr) |
| TW (1) | TW243445B (fr) |
| WO (1) | WO1994017040A1 (fr) |
| ZA (1) | ZA94317B (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993016044A1 (fr) * | 1992-02-06 | 1993-08-19 | Merrell Dow Pharmaceuticals Inc. | Inversion de la resistance multi-medicament au moyen de derives de triphenyl-azacycloalcane |
| AU6366000A (en) * | 1999-07-23 | 2001-02-13 | Colorado State University Research Foundation | Multidrug resistance pump inhibitors and uses thereof |
| US6693099B2 (en) | 2000-10-17 | 2004-02-17 | The Procter & Gamble Company | Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance |
| US6376514B1 (en) | 2000-10-17 | 2002-04-23 | The Procter & Gamble Co. | Substituted six-membered heterocyclic compounds useful for treating multidrug resistance and compositions and methods thereof |
| AU2002363523A1 (en) * | 2001-11-07 | 2003-05-19 | Pharmacia Corporation | Methods of promoting uptake and nuclear accumulation of polyamides in eukaryotic cells |
| KR100656490B1 (ko) * | 2001-11-26 | 2006-12-12 | 삼성에스디아이 주식회사 | 풀칼라 유기전계 발광표시소자 및 그의 제조방법 |
| US8153184B2 (en) * | 2001-11-26 | 2012-04-10 | Samsung Mobile Display Co., Ltd. | Organic EL display device and method of manufacturing the same |
| CN111557432B (zh) | 2013-02-08 | 2023-08-04 | 通用磨坊公司 | 低钠食品 |
| CN110372571B (zh) * | 2018-04-12 | 2022-11-15 | 中国科学院大连化学物理研究所 | 一种2-(2,2-二芳基乙基)-环胺衍生物或盐及合成和应用与组合物 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1049377B (de) * | 1952-04-03 | 1959-01-29 | Abbott Laboratories, North Chicago, 111. (V. St. A.) | Verfahren zur Herstellung von substituierten Vinylpiperidinen |
| US2898339A (en) * | 1957-07-29 | 1959-08-04 | Wm S Merrell Co | N-substituted benzhydrol, benzhydryl, and benzhydrylidene piperidine |
| US3956296A (en) * | 1974-12-11 | 1976-05-11 | A. H. Robins Company, Incorporated | 1-Substituted-4-benzylpiperidines |
| US4035372A (en) * | 1976-08-13 | 1977-07-12 | G. D. Searle & Co. | 4-{[4-(Diphenylmethyl)-1-piperidinyl]methyl}benzenamines |
| EP0228893A3 (fr) * | 1985-12-20 | 1990-01-03 | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) | Amines arylalkyl-hétérocycliques N-substitués par un groupe aryloxyalkyl dans le traitement des allergies |
| US4851423A (en) * | 1986-12-10 | 1989-07-25 | Schering Corporation | Pharmaceutically active compounds |
| US4990511A (en) * | 1988-08-03 | 1991-02-05 | Takeda Chemical Industries, Ltd. | Amide compounds, their production and use |
| WO1990015599A1 (fr) * | 1989-06-19 | 1990-12-27 | The Wellcome Foundation Limited | Medicaments utiles dans la therapie du cancer et possedant des proprietes antihistaminiques |
| GB9000305D0 (en) * | 1990-01-06 | 1990-03-07 | Pfizer Ltd | Anticholinergic agents |
| EP0467435A3 (en) * | 1990-07-19 | 1992-04-01 | Akzo N.V. | Benzhydryl derivatives having calmodulin inhibitor properties |
| EP0471612B1 (fr) * | 1990-08-14 | 1998-01-28 | Roussel Uclaf | Nouveaux 19-Nor stéroides ayant en position 11béta une chaíne carbonée comportant une fonction amide, leur préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant |
| WO1993016044A1 (fr) * | 1992-02-06 | 1993-08-19 | Merrell Dow Pharmaceuticals Inc. | Inversion de la resistance multi-medicament au moyen de derives de triphenyl-azacycloalcane |
-
1993
- 1993-12-17 US US08/481,538 patent/US5648365A/en not_active Expired - Fee Related
- 1993-12-17 ES ES94906446T patent/ES2102830T3/es not_active Expired - Lifetime
- 1993-12-17 AT AT94906446T patent/ATE150748T1/de not_active IP Right Cessation
- 1993-12-17 WO PCT/US1993/012300 patent/WO1994017040A1/fr not_active Ceased
- 1993-12-17 KR KR1019950702950A patent/KR100377280B1/ko not_active Expired - Fee Related
- 1993-12-17 DE DE69309310T patent/DE69309310T2/de not_active Expired - Fee Related
- 1993-12-17 JP JP51701194A patent/JP3398748B2/ja not_active Expired - Fee Related
- 1993-12-17 HU HU9502195A patent/HUT72078A/hu unknown
- 1993-12-17 EP EP94906446A patent/EP0680470B1/fr not_active Expired - Lifetime
- 1993-12-17 DK DK94906446.3T patent/DK0680470T3/da active
- 1993-12-17 NZ NZ261414A patent/NZ261414A/en unknown
- 1993-12-17 AU AU60148/94A patent/AU679723B2/en not_active Ceased
- 1993-12-17 CA CA002152794A patent/CA2152794C/fr not_active Expired - Fee Related
-
1994
- 1994-01-17 ZA ZA94317A patent/ZA94317B/xx unknown
- 1994-01-18 TW TW083100396A patent/TW243445B/zh active
- 1994-01-19 IL IL10836994A patent/IL108369A/en not_active IP Right Cessation
- 1994-01-20 MX MX9400563A patent/MX9400563A/es not_active IP Right Cessation
-
1995
- 1995-07-20 FI FI953506A patent/FI112474B/fi active
- 1995-07-20 NO NO952885A patent/NO305166B1/no not_active IP Right Cessation
-
1997
- 1997-04-21 GR GR970400848T patent/GR3023188T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2152794A1 (fr) | 1994-08-04 |
| DE69309310D1 (de) | 1997-04-30 |
| EP0680470B1 (fr) | 1997-03-26 |
| GR3023188T3 (en) | 1997-07-30 |
| IL108369A (en) | 1999-08-17 |
| KR100377280B1 (ko) | 2003-07-18 |
| AU679723B2 (en) | 1997-07-10 |
| ES2102830T3 (es) | 1997-08-01 |
| KR960700230A (ko) | 1996-01-19 |
| MX9400563A (es) | 1994-07-29 |
| AU6014894A (en) | 1994-08-15 |
| WO1994017040A1 (fr) | 1994-08-04 |
| FI953506L (fi) | 1995-07-20 |
| FI112474B (fi) | 2003-12-15 |
| CA2152794C (fr) | 1999-04-06 |
| NO952885D0 (no) | 1995-07-20 |
| NO952885L (no) | 1995-09-20 |
| ZA94317B (en) | 1994-08-18 |
| NO305166B1 (no) | 1999-04-12 |
| JPH08505870A (ja) | 1996-06-25 |
| DE69309310T2 (de) | 1997-11-06 |
| JP3398748B2 (ja) | 2003-04-21 |
| US5648365A (en) | 1997-07-15 |
| TW243445B (fr) | 1995-03-21 |
| HUT72078A (en) | 1996-03-28 |
| IL108369A0 (en) | 1994-04-12 |
| EP0680470A1 (fr) | 1995-11-08 |
| FI953506A0 (fi) | 1995-07-20 |
| ATE150748T1 (de) | 1997-04-15 |
| NZ261414A (en) | 1997-06-24 |
| HU9502195D0 (en) | 1995-09-28 |
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