DK0667856T3 - Nye D-vitaminanaloger - Google Patents
Nye D-vitaminanalogerInfo
- Publication number
- DK0667856T3 DK0667856T3 DK93924535T DK93924535T DK0667856T3 DK 0667856 T3 DK0667856 T3 DK 0667856T3 DK 93924535 T DK93924535 T DK 93924535T DK 93924535 T DK93924535 T DK 93924535T DK 0667856 T3 DK0667856 T3 DK 0667856T3
- Authority
- DK
- Denmark
- Prior art keywords
- pct
- date
- analogs
- sec
- compounds
- Prior art date
Links
- 239000011710 vitamin D Substances 0.000 title abstract 2
- 229940046008 vitamin d Drugs 0.000 title abstract 2
- 229930003316 Vitamin D Natural products 0.000 title 1
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 title 1
- 235000019166 vitamin D Nutrition 0.000 title 1
- 150000003710 vitamin D derivatives Chemical class 0.000 title 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000002519 immonomodulatory effect Effects 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
- A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929223061A GB9223061D0 (en) | 1992-11-04 | 1992-11-04 | Chemical compounds |
| PCT/DK1993/000351 WO1994010139A1 (en) | 1992-11-04 | 1993-11-01 | Novel vitamin d analogues |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0667856T3 true DK0667856T3 (da) | 1998-09-28 |
Family
ID=10724491
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK93924535T DK0667856T3 (da) | 1992-11-04 | 1993-11-01 | Nye D-vitaminanaloger |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5710142A (da) |
| EP (1) | EP0667856B1 (da) |
| JP (1) | JPH08503700A (da) |
| KR (1) | KR100301214B1 (da) |
| AT (1) | ATE163007T1 (da) |
| AU (1) | AU671326B2 (da) |
| CA (1) | CA2144161A1 (da) |
| DE (1) | DE69316910T2 (da) |
| DK (1) | DK0667856T3 (da) |
| ES (1) | ES2114619T3 (da) |
| FI (1) | FI109687B (da) |
| GB (1) | GB9223061D0 (da) |
| GR (1) | GR3026647T3 (da) |
| NZ (1) | NZ257533A (da) |
| RU (1) | RU2128168C1 (da) |
| WO (1) | WO1994010139A1 (da) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9314400D0 (en) * | 1993-07-12 | 1993-08-25 | Leo Pharm Prod Ltd | Produktionsaktieselskab) chemical compounds |
| US6103709A (en) * | 1993-12-23 | 2000-08-15 | The Regents Of The University Of California | Therapeutically effective 1α,25-dihydroxyvitamin D3 analogs and methods for treatment of vitamin D diseases |
| US6121469A (en) | 1993-12-23 | 2000-09-19 | The Regents Of The University Of California | Therapeutically effective 1α,25-dihydroxyvitamin D3 analogs |
| US6242434B1 (en) * | 1997-08-08 | 2001-06-05 | Bone Care International, Inc. | 24-hydroxyvitamin D, analogs and uses thereof |
| US20040043971A1 (en) * | 1995-04-03 | 2004-03-04 | Bone Care International, Inc. | Method of treating and preventing hyperparathyroidism with active vitamin D analogs |
| US20020183288A1 (en) * | 1995-04-03 | 2002-12-05 | Bone Care International, Inc. | Method for treating and preventing hyperparathyroidism |
| GB9611603D0 (en) | 1996-06-04 | 1996-08-07 | Leo Pharm Prod Ltd | Chemical compounds |
| GB9622590D0 (en) * | 1996-10-30 | 1997-01-08 | Leo Pharm Prod Ltd | Chemical compounds |
| US5972917A (en) * | 1998-05-29 | 1999-10-26 | Bone Care Int Inc | 1 α-hydroxy-25-ene-vitamin D, analogs and uses thereof |
| US6358939B1 (en) | 1999-12-21 | 2002-03-19 | Northern Lights Pharmaceuticals, Llc | Use of biologically active vitamin D compounds for the prevention and treatment of inflammatory bowel disease |
| US6989377B2 (en) | 1999-12-21 | 2006-01-24 | Wisconsin Alumni Research Foundation | Treating vitamin D responsive diseases |
| ATE428692T1 (de) * | 2001-08-22 | 2009-05-15 | Univ Johns Hopkins | 24-schwefel-substituierte 1-alpha-25-dihydroxy- vitamin-d3-analogen |
| ATE543796T1 (de) | 2002-06-13 | 2012-02-15 | Univ Johns Hopkins | 24-sulfoximine vitamin d3 derivate |
| AU2003292920A1 (en) | 2002-12-18 | 2004-07-09 | Cytochroma Inc. | 25-so2-substituted analogs of 1alpha, 25-dihydroxyvitamin d3 (calcitriol) |
| US8404667B2 (en) * | 2006-12-29 | 2013-03-26 | Wisconsin Alumni Research Foundation | Compounds, compositions, kits and methods of use to orally and topically treat acne and other skin conditions by 19-Nor vitamin D analog |
| US7094775B2 (en) * | 2004-06-30 | 2006-08-22 | Bone Care International, Llc | Method of treating breast cancer using a combination of vitamin D analogues and other agents |
| US20060003950A1 (en) * | 2004-06-30 | 2006-01-05 | Bone Care International, Inc. | Method of treating prostatic diseases using a combination of vitamin D analogues and other agents |
| JP2008519808A (ja) | 2004-11-12 | 2008-06-12 | ビオエクセル エスピーエー | 膀胱癌治療のためのビタミンd誘導体及び抗増殖薬の併用 |
| US8425784B2 (en) * | 2007-11-05 | 2013-04-23 | University Of Kansas | Ozonolysis reactions in liquid CO2 and CO2-expanded solvents |
| CA2981549A1 (en) | 2009-01-27 | 2010-08-05 | Berg Llc | Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy |
| AU2010282731C1 (en) | 2009-08-14 | 2016-04-21 | Berg Llc | Vitamin D3 and analogs thereof for treating alopecia |
| CA2913543C (en) | 2013-05-29 | 2024-01-09 | Berg Llc | Preventing or mitigating chemotherapy induced alopecia using vitamin d |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4617297A (en) * | 1982-02-12 | 1986-10-14 | Hoffmann-La Roche Inc. | Method of treating disease states by the administration of 1α,25,26-trihydroxycholecalciferol |
| US4594432A (en) * | 1983-01-28 | 1986-06-10 | Hoffman-La Roche Inc. | Process for the synthesis of 1α,23(S),25-trihydroxycholecalciferol and 1α,23(R),25-trihydroxycholecalciferol |
| US4719205A (en) * | 1984-01-30 | 1988-01-12 | Wisconsin Alumini Research Foundation | Side-chain unsaturated 1-hydroxyvitamin D compounds |
| JPS6144860A (ja) * | 1984-08-10 | 1986-03-04 | Taisho Pharmaceut Co Ltd | 1α.25−ジヒドロキシ−26.27−ジメチルビタミンD↓3 |
| US4612308A (en) * | 1984-11-29 | 1986-09-16 | Hoffmann-La Roche Inc. | 25,26-Dehydro-1α,23(S,R)-dihydroxycholecalciferol and its epimers |
| ATE45347T1 (de) * | 1985-05-30 | 1989-08-15 | Taisho Pharmaceutical Co Ltd | Vitamin d3-derivate. |
| WO1987003282A1 (fr) * | 1985-11-21 | 1987-06-04 | Taisho Pharmaceutical Co., Ltd. | Derive de la vitamine d3 |
| US4804502A (en) * | 1988-01-20 | 1989-02-14 | Hoffmann-La Roche Inc. | Vitamin D compounds |
| US4851401A (en) * | 1988-07-14 | 1989-07-25 | Wisconsin Alumni Research Foundation | Novel cyclopentano-vitamin D analogs |
| GB8915770D0 (en) * | 1989-07-10 | 1989-08-31 | Leo Pharm Prod Ltd | Chemical compounds |
| EP0441467B1 (de) * | 1990-02-06 | 1994-06-01 | Schering Aktiengesellschaft | Seitenketten-homologe Vitamin-D-Derivate, Verfahren zu ihrer Herstellung, diese enthaltende pharmazeutische Präparate, sowie deren Verwendung als Arzneimittel |
| US5260290A (en) * | 1990-02-14 | 1993-11-09 | Wisconsin Alumni Research Foundation | Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives |
| GB9007236D0 (en) * | 1990-03-30 | 1990-05-30 | Leo Pharm Prod Ltd | Chemical compounds |
| DE4011682A1 (de) * | 1990-04-06 | 1991-10-10 | Schering Ag | 24-oxa-derivate in der vitamin d-reihe |
| US5486509A (en) * | 1991-06-28 | 1996-01-23 | University Of Miami | Method of preventing and treating chemotherapy-induced alopecia |
| US5200536A (en) * | 1992-02-10 | 1993-04-06 | Daikin Industries Ltd. | Fluorine-containing vitamin D3 analogues |
| US5194431A (en) * | 1992-07-08 | 1993-03-16 | Wisconsin Alumni Research Foundation | 24-cyclopropane vitamin D derivatives |
-
1992
- 1992-11-04 GB GB929223061A patent/GB9223061D0/en active Pending
-
1993
- 1993-11-01 DK DK93924535T patent/DK0667856T3/da active
- 1993-11-01 WO PCT/DK1993/000351 patent/WO1994010139A1/en not_active Ceased
- 1993-11-01 AU AU54181/94A patent/AU671326B2/en not_active Ceased
- 1993-11-01 EP EP93924535A patent/EP0667856B1/en not_active Expired - Lifetime
- 1993-11-01 NZ NZ257533A patent/NZ257533A/en unknown
- 1993-11-01 US US08/428,187 patent/US5710142A/en not_active Expired - Fee Related
- 1993-11-01 KR KR1019950700999A patent/KR100301214B1/ko not_active Expired - Fee Related
- 1993-11-01 AT AT93924535T patent/ATE163007T1/de not_active IP Right Cessation
- 1993-11-01 CA CA002144161A patent/CA2144161A1/en not_active Abandoned
- 1993-11-01 ES ES93924535T patent/ES2114619T3/es not_active Expired - Lifetime
- 1993-11-01 RU RU95113157A patent/RU2128168C1/ru not_active IP Right Cessation
- 1993-11-01 DE DE69316910T patent/DE69316910T2/de not_active Expired - Fee Related
- 1993-11-01 JP JP6510578A patent/JPH08503700A/ja not_active Ceased
-
1995
- 1995-04-25 FI FI951968A patent/FI109687B/fi active
-
1998
- 1998-04-15 GR GR980400848T patent/GR3026647T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU95113157A (ru) | 1996-11-20 |
| GB9223061D0 (en) | 1992-12-16 |
| ES2114619T3 (es) | 1998-06-01 |
| FI951968A0 (fi) | 1995-04-25 |
| DE69316910D1 (de) | 1998-03-12 |
| EP0667856B1 (en) | 1998-02-04 |
| AU5418194A (en) | 1994-05-24 |
| NZ257533A (en) | 1997-06-24 |
| FI951968A7 (fi) | 1995-04-25 |
| FI109687B (fi) | 2002-09-30 |
| JPH08503700A (ja) | 1996-04-23 |
| CA2144161A1 (en) | 1994-05-11 |
| ATE163007T1 (de) | 1998-02-15 |
| RU2128168C1 (ru) | 1999-03-27 |
| WO1994010139A1 (en) | 1994-05-11 |
| GR3026647T3 (en) | 1998-07-31 |
| KR100301214B1 (ko) | 2001-11-22 |
| EP0667856A1 (en) | 1995-08-23 |
| AU671326B2 (en) | 1996-08-22 |
| DE69316910T2 (de) | 1998-10-01 |
| US5710142A (en) | 1998-01-20 |
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