DK0666743T3 - Opløselige calciumlactat/quindoncarboxylsyrer-komplekser som ikke-irriterende parenterale former - Google Patents
Opløselige calciumlactat/quindoncarboxylsyrer-komplekser som ikke-irriterende parenterale formerInfo
- Publication number
- DK0666743T3 DK0666743T3 DK93923156T DK93923156T DK0666743T3 DK 0666743 T3 DK0666743 T3 DK 0666743T3 DK 93923156 T DK93923156 T DK 93923156T DK 93923156 T DK93923156 T DK 93923156T DK 0666743 T3 DK0666743 T3 DK 0666743T3
- Authority
- DK
- Denmark
- Prior art keywords
- calcium lactate
- quindone
- irritating
- carboxylic acid
- soluble calcium
- Prior art date
Links
- MKJXYGKVIBWPFZ-UHFFFAOYSA-L calcium lactate Chemical compound [Ca+2].CC(O)C([O-])=O.CC(O)C([O-])=O MKJXYGKVIBWPFZ-UHFFFAOYSA-L 0.000 title abstract 2
- 229960002401 calcium lactate Drugs 0.000 title abstract 2
- 235000011086 calcium lactate Nutrition 0.000 title abstract 2
- 239000001527 calcium lactate Substances 0.000 title abstract 2
- 150000001732 carboxylic acid derivatives Chemical class 0.000 title 1
- 231100000344 non-irritating Toxicity 0.000 title 1
- FLBAYUMRQUHISI-UHFFFAOYSA-N 1,8-naphthyridine Chemical compound N1=CC=CC2=CC=CN=C21 FLBAYUMRQUHISI-UHFFFAOYSA-N 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 230000007794 irritation Effects 0.000 abstract 1
- 239000006201 parenteral dosage form Substances 0.000 abstract 1
- LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical compound C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/966,998 US5290794A (en) | 1992-10-27 | 1992-10-27 | Soluble calcium lactate antibacterial complexes as non-irritating parenteral forms |
| PCT/US1993/009252 WO1994009779A1 (en) | 1992-10-27 | 1993-09-29 | Soluble calcium lactate/quindonecarboxylic acids on naphthydrinecarboxylic acids complexes as non-irritating parenteral forms |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0666743T3 true DK0666743T3 (da) | 1999-08-16 |
Family
ID=25512170
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK93923156T DK0666743T3 (da) | 1992-10-27 | 1993-09-29 | Opløselige calciumlactat/quindoncarboxylsyrer-komplekser som ikke-irriterende parenterale former |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5290794A (da) |
| EP (1) | EP0666743B1 (da) |
| JP (1) | JPH08504190A (da) |
| AT (1) | ATE173925T1 (da) |
| AU (1) | AU670838B2 (da) |
| CA (1) | CA2144652A1 (da) |
| DE (1) | DE69322405T2 (da) |
| DK (1) | DK0666743T3 (da) |
| ES (1) | ES2124797T3 (da) |
| MX (1) | MX9306321A (da) |
| NZ (1) | NZ256962A (da) |
| SG (1) | SG46482A1 (da) |
| WO (1) | WO1994009779A1 (da) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5602254A (en) * | 1995-05-26 | 1997-02-11 | Warner-Lambert Company | Method for making quinoline carboxylic acids or naphthyridine carboxylic acids in free base form |
| ID21415A (id) * | 1997-12-05 | 1999-06-10 | Upjohn Co | Senyawa-senyawa antibiotik magnesium quinolon |
| TW200612941A (en) * | 2004-07-02 | 2006-05-01 | Daiichi Seiyaku Co | Quinorone-containing pharmaceutical composition |
| CA2693473A1 (en) * | 2007-07-17 | 2009-01-22 | Amgen Inc. | Thiadiazole modulators of pkb |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR223983A1 (es) * | 1978-08-25 | 1981-10-15 | Dainippon Pharmaceutical Co | Un procedimiento para-preparar derivados de acido 6-halogeno-4-oxo-7-(1-piperazinil)-1,8-naftiridin-3-carboxilico |
| DE3508816A1 (de) * | 1985-01-10 | 1986-07-10 | Bayer Ag, 5090 Leverkusen | 6,7-disubstituierte 1-cyclopropyl-1,4-dihydro-4-oxo-1,8-naphtyridin-3-carbonsaeuren |
| US4771054A (en) * | 1985-01-23 | 1988-09-13 | Warner-Lambert Company | Antibacterial agents |
| DE3537761A1 (de) * | 1985-10-24 | 1987-04-30 | Bayer Ag | Infusionsloesungen der 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7- (1-piperazinyl)-chinolin-3-carbonsaeure |
| AU594983B2 (en) * | 1985-10-29 | 1990-03-22 | Dainippon Pharmaceutical Co. Ltd. | Novel quinoline derivatives and processes for preparation thereof |
| DE3713672A1 (de) * | 1987-04-24 | 1988-11-17 | Bayer Ag | Verfahren zur herstellung von parenteral verabreichbaren chinoloncarbonsaeuren |
| US4851418A (en) * | 1987-08-21 | 1989-07-25 | Warner-Lambert Company | Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent |
| US4929613A (en) * | 1987-08-26 | 1990-05-29 | Warner-Lambert Company | Antibacterial agents |
| DE3831514A1 (de) * | 1988-09-16 | 1990-03-22 | Bayer Ag | Ph-neutrale waessrige loesungen von chinoloncarbonsaeuren |
| US5057520A (en) * | 1989-03-24 | 1991-10-15 | Abbott Laboratories | 7-(peptidylpyrolidinyl)naphthyridine antibacterial compounds |
| US4916141A (en) * | 1989-03-28 | 1990-04-10 | Warner-Lambert Company | (S)-7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid |
| NZ232740A (en) * | 1989-04-20 | 1992-06-25 | Riker Laboratories Inc | Solution for parenteral administration comprising a 1h-imidazo(4,5-c) quinolin-4-amine derivative, an acid and a tonicity adjuster |
| JPH085779B2 (ja) * | 1989-09-22 | 1996-01-24 | 杏林製薬株式会社 | フレロキサシン点眼液 |
| EP0425443A1 (de) * | 1989-10-27 | 1991-05-02 | Ciba-Geigy Ag | Injizierbares parasitizides Mittel |
| JP3153549B2 (ja) * | 1989-12-29 | 2001-04-09 | アボツト・ラボラトリーズ | キノロンカルボン酸―金属イオン―酸錯体 |
-
1992
- 1992-10-27 US US07/966,998 patent/US5290794A/en not_active Expired - Fee Related
-
1993
- 1993-09-29 ES ES93923156T patent/ES2124797T3/es not_active Expired - Lifetime
- 1993-09-29 NZ NZ256962A patent/NZ256962A/en unknown
- 1993-09-29 WO PCT/US1993/009252 patent/WO1994009779A1/en not_active Ceased
- 1993-09-29 SG SG1996005004A patent/SG46482A1/en unknown
- 1993-09-29 CA CA002144652A patent/CA2144652A1/en not_active Abandoned
- 1993-09-29 JP JP6511062A patent/JPH08504190A/ja active Pending
- 1993-09-29 DK DK93923156T patent/DK0666743T3/da active
- 1993-09-29 EP EP93923156A patent/EP0666743B1/en not_active Expired - Lifetime
- 1993-09-29 DE DE69322405T patent/DE69322405T2/de not_active Expired - Fee Related
- 1993-09-29 AU AU52937/93A patent/AU670838B2/en not_active Ceased
- 1993-09-29 AT AT93923156T patent/ATE173925T1/de not_active IP Right Cessation
- 1993-10-11 MX MX9306321A patent/MX9306321A/es not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1994009779A1 (en) | 1994-05-11 |
| AU5293793A (en) | 1994-05-24 |
| CA2144652A1 (en) | 1994-05-11 |
| DE69322405T2 (de) | 1999-04-29 |
| AU670838B2 (en) | 1996-08-01 |
| SG46482A1 (en) | 1998-02-20 |
| DE69322405D1 (de) | 1999-01-14 |
| ATE173925T1 (de) | 1998-12-15 |
| MX9306321A (es) | 1994-04-29 |
| JPH08504190A (ja) | 1996-05-07 |
| EP0666743A1 (en) | 1995-08-16 |
| US5290794A (en) | 1994-03-01 |
| ES2124797T3 (es) | 1999-02-16 |
| NZ256962A (en) | 1996-08-27 |
| EP0666743B1 (en) | 1998-12-02 |
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