DK0652973T3 - Fremgangsmåde til indføring af definerede sekvenser ved 3-enden af polynukleotider - Google Patents
Fremgangsmåde til indføring af definerede sekvenser ved 3-enden af polynukleotiderInfo
- Publication number
- DK0652973T3 DK0652973T3 DK93917347.2T DK93917347T DK0652973T3 DK 0652973 T3 DK0652973 T3 DK 0652973T3 DK 93917347 T DK93917347 T DK 93917347T DK 0652973 T3 DK0652973 T3 DK 0652973T3
- Authority
- DK
- Denmark
- Prior art keywords
- polynucleotide
- primer
- sequences
- sequence
- blocker
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92307992A | 1992-07-31 | 1992-07-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0652973T3 true DK0652973T3 (da) | 1997-09-15 |
Family
ID=25448085
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK93917347.2T DK0652973T3 (da) | 1992-07-31 | 1993-07-30 | Fremgangsmåde til indføring af definerede sekvenser ved 3-enden af polynukleotider |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US5679512A (es) |
| EP (1) | EP0652973B1 (es) |
| JP (1) | JPH07509365A (es) |
| AT (1) | ATE152180T1 (es) |
| CA (1) | CA2141450A1 (es) |
| DE (1) | DE69310179T2 (es) |
| DK (1) | DK0652973T3 (es) |
| ES (1) | ES2104160T3 (es) |
| WO (1) | WO1994003637A1 (es) |
Families Citing this family (92)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0790861A1 (en) * | 1995-09-12 | 1997-08-27 | Becton, Dickinson and Company | Device and method for dna amplification and assay |
| US6482590B1 (en) | 1996-12-20 | 2002-11-19 | Aventis Behring Gmbh | Method for polynucleotide amplification |
| US20030165888A1 (en) * | 2001-07-18 | 2003-09-04 | Brown Bob D. | Oligonucleotide probes and primers comprising universal bases for diagnostic purposes |
| US6518017B1 (en) * | 1997-10-02 | 2003-02-11 | Oasis Biosciences Incorporated | Combinatorial antisense library |
| BR9814912A (pt) * | 1997-11-28 | 2000-10-03 | Genset Sa | Sequência genÈmica e polipeptìdeos de chlamydia trachomatis, fragmentos dos mesmos e usos dos mesmos, em particular para o diagnóstico, a prevenção e o tratamento de infecção |
| US6289229B1 (en) | 1998-01-20 | 2001-09-11 | Scimed Life Systems, Inc. | Readable probe array for in vivo use |
| DE1051515T1 (de) | 1998-01-27 | 2001-04-19 | Cytocell Ltd., Banbury | Modifizierte nuklein-säure sonden und dessen verwendungen |
| AU777910B2 (en) * | 1999-04-08 | 2004-11-04 | Gen-Probe Incorporated | Amplification and sequencing primer pairs and use thereof |
| AU777499B2 (en) * | 1999-04-08 | 2004-10-21 | Gen-Probe Incorporated | Antisense oligonucleotides comprising universal and/or degenerate bases |
| IL148091A0 (en) | 1999-09-13 | 2002-09-12 | Nugen Technologies Inc | Methods and compositions for linear isothermal amplification of polynucleotide sequences |
| US6692918B2 (en) | 1999-09-13 | 2004-02-17 | Nugen Technologies, Inc. | Methods and compositions for linear isothermal amplification of polynucleotide sequences |
| DE60141087D1 (de) | 2000-06-26 | 2010-03-04 | Nugen Technologies Inc | Methoden und zusammensetzungen zur auf transkription basierenden vervielfältigung von nukleinsäuren |
| US7846733B2 (en) | 2000-06-26 | 2010-12-07 | Nugen Technologies, Inc. | Methods and compositions for transcription-based nucleic acid amplification |
| US6994963B1 (en) * | 2000-07-10 | 2006-02-07 | Ambion, Inc. | Methods for recombinatorial nucleic acid synthesis |
| CA2423729A1 (en) | 2000-10-06 | 2002-04-11 | Nugen Technologies, Inc. | Methods and probes for detection and/or quantification of nucleic acid sequences |
| CA2436693A1 (en) * | 2000-12-11 | 2002-06-20 | Alexion Pharmaceuticals, Inc. | Nested oligonucleotides containing hairpin for nucleic acid amplification |
| CA2430329A1 (en) | 2000-12-13 | 2002-06-20 | Nugen Technologies, Inc. | Methods and compositions for generation of multiple copies of nucleic acid sequences and methods of detection thereof |
| CA2439074A1 (en) | 2001-03-09 | 2002-09-19 | Nugen Technologies, Inc. | Methods and compositions for amplification of rna sequences |
| WO2002072772A2 (en) | 2001-03-09 | 2002-09-19 | Nugen Technologies, Inc. | Methods and compositions for amplification of rna sequences |
| WO2003016546A1 (en) * | 2001-08-21 | 2003-02-27 | Flinders Technologies Pty Ltd. | Method and device for simultaneously molecularly cloning and polylocus profiling of genomes or genome mixtures |
| US7414111B2 (en) * | 2001-09-19 | 2008-08-19 | Alexion Pharmaceuticals, Inc. | Engineered templates and their use in single primer amplification |
| AU2002341752B2 (en) * | 2001-09-19 | 2008-04-03 | Alexion Pharmaceuticals, Inc. | Engineered templates and their use in single primer amplification |
| US7045319B2 (en) * | 2001-10-30 | 2006-05-16 | Ribomed Biotechnologies, Inc. | Molecular detection systems utilizing reiterative oligonucleotide synthesis |
| US20040054162A1 (en) * | 2001-10-30 | 2004-03-18 | Hanna Michelle M. | Molecular detection systems utilizing reiterative oligonucleotide synthesis |
| CA2478875A1 (en) * | 2002-03-11 | 2003-09-25 | Nugen Technologies, Inc. | Methods for generating double stranded dna comprising a 3' single stranded portion and uses of these complexes for recombination |
| AU2003279697A1 (en) * | 2002-05-17 | 2004-02-16 | Nugen Technologies, Inc. | Methods for fragmentation, labeling and immobilizaton of nucleic acids |
| ATE411400T1 (de) | 2002-11-21 | 2008-10-15 | Epict Technologies | Verfahren zur verwendung von riboprimern zur strangverdrängungsreplikation von zielsequenzen |
| JP2006523465A (ja) | 2003-04-14 | 2006-10-19 | ニューゲン テクノロジーズ， インコーポレイテッド | ランダムにプライミングされる複合プライマーを用いる大規模増幅 |
| US20050214796A1 (en) * | 2003-10-29 | 2005-09-29 | Hanna Michelle M | Compositions, methods and detection technologies for reiterative oligonucleotide synthesis |
| US20050208538A1 (en) | 2003-12-29 | 2005-09-22 | Nurith Kurn | Methods for analysis of nucleic acid methylation status and methods for fragmentation, labeling and immobilization of nucleic acids |
| BRPI0607378A2 (pt) | 2005-02-26 | 2010-03-23 | Basf Plant Science Gmbh | cassetes de expressço, seqÜÊncia nucleotÍdica isolada, vetor, cÉlula hospedeira transgÊnica ou organismo nço humano, cÉlula de planta ou planta transgÊnica, mÉtodos para identificar e/ou isolar uma seqÜÊncia nucleotÍdica reguladora da transcriÇço, para prover ou produzir um cassete de expressço transgÊnica, e para prover uma seqÜÊncia nucleotÍdica reguladora de transcriÇço sintÉtica, e, seqÜÊncia reguladora de transcriÇço sintÉtica |
| US7939258B2 (en) | 2005-09-07 | 2011-05-10 | Nugen Technologies, Inc. | Nucleic acid amplification procedure using RNA and DNA composite primers |
| DE102006020885A1 (de) * | 2006-05-05 | 2007-11-08 | Qiagen Gmbh | Einführung von Sequenzelementen in Nukleinsäuren |
| EP2038429B1 (en) * | 2006-06-30 | 2013-08-21 | Nugen Technologies, Inc. | Methods for fragmentation and labeling of nucleic acids |
| WO2009006438A2 (en) | 2007-06-29 | 2009-01-08 | Epicentre Technologies Corporation | Copy dna and sense rna |
| US8034568B2 (en) | 2008-02-12 | 2011-10-11 | Nugen Technologies, Inc. | Isothermal nucleic acid amplification methods and compositions |
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| US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| EP2763701B1 (en) | 2011-10-03 | 2018-12-19 | Moderna Therapeutics, Inc. | Modified nucleosides, nucleotides, and nucleic acids, and uses thereof |
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| DE18200782T1 (de) | 2012-04-02 | 2021-10-21 | Modernatx, Inc. | Modifizierte polynukleotide zur herstellung von proteinen im zusammenhang mit erkrankungen beim menschen |
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| US9878056B2 (en) | 2012-04-02 | 2018-01-30 | Modernatx, Inc. | Modified polynucleotides for the production of cosmetic proteins and peptides |
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| CN110366613A (zh) | 2016-12-16 | 2019-10-22 | 特韦斯特生物科学公司 | 免疫突触的变体文库及其合成 |
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| IL271205B2 (en) | 2017-06-12 | 2025-02-01 | Twist Bioscience Corp | Methods for assembling continuous nucleic acids |
| US11407837B2 (en) | 2017-09-11 | 2022-08-09 | Twist Bioscience Corporation | GPCR binding proteins and synthesis thereof |
| US11099202B2 (en) | 2017-10-20 | 2021-08-24 | Tecan Genomics, Inc. | Reagent delivery system |
| KR102637566B1 (ko) | 2017-10-20 | 2024-02-16 | 트위스트 바이오사이언스 코포레이션 | 폴리뉴클레오타이드 합성을 위한 가열된 나노웰 |
| CN111511925B (zh) * | 2017-11-29 | 2023-11-14 | 帕纳金股份有限公司 | 用于扩增靶核酸的方法及用于扩张靶核酸的组合物 |
| CN112041438B (zh) | 2018-01-04 | 2025-05-23 | 特韦斯特生物科学公司 | 基于dna的数字信息存储 |
| CA3100739A1 (en) | 2018-05-18 | 2019-11-21 | Twist Bioscience Corporation | Polynucleotides, reagents, and methods for nucleic acid hybridization |
| CA3124980A1 (en) | 2018-12-26 | 2020-07-02 | Twist Bioscience Corporation | Highly accurate de novo polynucleotide synthesis |
| US20210002710A1 (en) * | 2019-02-25 | 2021-01-07 | Twist Bioscience Corporation | Compositions and methods for next generation sequencing |
| CN113785057A (zh) | 2019-02-26 | 2021-12-10 | 特韦斯特生物科学公司 | 用于抗体优化的变异核酸文库 |
| KR20210143766A (ko) | 2019-02-26 | 2021-11-29 | 트위스트 바이오사이언스 코포레이션 | Glp1 수용체에 대한 변이체 핵산 라이브러리 |
| JP2022550497A (ja) | 2019-06-21 | 2022-12-02 | ツイスト バイオサイエンス コーポレーション | バーコードに基づいた核酸配列アセンブリ |
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| CA3155629A1 (en) | 2019-09-23 | 2021-04-01 | Twist Bioscience Corporation | Variant nucleic acid libraries for crth2 |
| CN113275053A (zh) | 2020-02-03 | 2021-08-20 | 帝肯基因组学公司 | 试剂存储系统 |
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1993
- 1993-07-30 CA CA002141450A patent/CA2141450A1/en not_active Abandoned
- 1993-07-30 WO PCT/US1993/007051 patent/WO1994003637A1/en not_active Ceased
- 1993-07-30 JP JP6505390A patent/JPH07509365A/ja not_active Ceased
- 1993-07-30 EP EP93917347A patent/EP0652973B1/en not_active Expired - Lifetime
- 1993-07-30 DE DE69310179T patent/DE69310179T2/de not_active Expired - Fee Related
- 1993-07-30 DK DK93917347.2T patent/DK0652973T3/da active
- 1993-07-30 AT AT93917347T patent/ATE152180T1/de active
- 1993-07-30 ES ES93917347T patent/ES2104160T3/es not_active Expired - Lifetime
- 1993-10-20 US US08/140,349 patent/US5679512A/en not_active Expired - Fee Related
-
1995
- 1995-06-07 US US08/475,236 patent/US5683879A/en not_active Expired - Fee Related
- 1995-06-07 US US08/479,745 patent/US6030774A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO1994003637A1 (en) | 1994-02-17 |
| US5679512A (en) | 1997-10-21 |
| JPH07509365A (ja) | 1995-10-19 |
| ES2104160T3 (es) | 1997-10-01 |
| EP0652973A1 (en) | 1995-05-17 |
| DE69310179D1 (de) | 1997-05-28 |
| DE69310179T2 (de) | 1997-07-31 |
| ATE152180T1 (de) | 1997-05-15 |
| CA2141450A1 (en) | 1994-02-17 |
| US5683879A (en) | 1997-11-04 |
| US6030774A (en) | 2000-02-29 |
| EP0652973B1 (en) | 1997-04-23 |
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