DK0641789T3 - Benzothiadiazinderivater - Google Patents
BenzothiadiazinderivaterInfo
- Publication number
- DK0641789T3 DK0641789T3 DK92910342.2T DK92910342T DK0641789T3 DK 0641789 T3 DK0641789 T3 DK 0641789T3 DK 92910342 T DK92910342 T DK 92910342T DK 0641789 T3 DK0641789 T3 DK 0641789T3
- Authority
- DK
- Denmark
- Prior art keywords
- methylene
- substituted
- lower alkyl
- hydrate
- halogen
- Prior art date
Links
- HAVZTGSQJIEKPI-UHFFFAOYSA-N benzothiadiazine Chemical compound C1=CC=C2C=NNSC2=C1 HAVZTGSQJIEKPI-UHFFFAOYSA-N 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 3
- -1 acetoxyacetyl Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 150000002431 hydrogen Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000000843 phenylene group Chemical group C1(=C(C=CC=C1)*)* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 208000008469 Peptic Ulcer Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000004450 alkenylene group Chemical group 0.000 abstract 1
- 150000007658 benzothiadiazines Chemical class 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 125000004210 cyclohexylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000001160 methoxycarbonyl group Chemical group [H]C([H])([H])OC(*)=O 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 150000002829 nitrogen Chemical class 0.000 abstract 1
- 208000011906 peptic ulcer disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/15—Six-membered rings
- C07D285/16—Thiadiazines; Hydrogenated thiadiazines
- C07D285/18—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines
- C07D285/20—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems
- C07D285/22—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D285/24—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP14992791 | 1991-05-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0641789T3 true DK0641789T3 (da) | 1998-02-02 |
Family
ID=15485620
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK92910342.2T DK0641789T3 (da) | 1991-05-24 | 1992-05-22 | Benzothiadiazinderivater |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5401739A (da) |
| EP (1) | EP0641789B1 (da) |
| KR (1) | KR970002467B1 (da) |
| AT (1) | ATE160776T1 (da) |
| AU (1) | AU655986B2 (da) |
| CA (1) | CA2109723C (da) |
| DE (1) | DE69223422T2 (da) |
| DK (1) | DK0641789T3 (da) |
| ES (1) | ES2111637T3 (da) |
| GR (1) | GR3025669T3 (da) |
| HU (1) | HU211585A9 (da) |
| WO (1) | WO1992020666A1 (da) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002020500A2 (en) * | 2000-09-01 | 2002-03-14 | Icos Corporation | Materials and methods to potentiate cancer treatment |
| US8404681B2 (en) | 2003-03-24 | 2013-03-26 | Luitpold Pharmaceuticals, Inc. | Xanthones, thioxanthones and acridinones as DNA-PK inhibitors |
| CN103058958A (zh) * | 2011-10-22 | 2013-04-24 | 杭州福斯特药业有限公司 | 一种罗沙替丁醋酸酯盐酸盐的合成方法 |
| CN105859654B (zh) * | 2016-04-20 | 2018-01-12 | 安徽峆一药业股份有限公司 | 罗沙替丁中间体3‑(1‑哌啶甲基)苯酚的合成方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4590192A (en) * | 1982-10-01 | 1986-05-20 | Beecham Group P.L.C. | Benzisothiazoles, their pharmaceutical compositions, and method of use |
| JPS59116277A (ja) * | 1982-10-01 | 1984-07-05 | ビ−チヤム・グル−プ・ピ−エルシ− | 新規化合物 |
| US4558044A (en) * | 1983-02-19 | 1985-12-10 | Beecham Group P.L.C. | 1,2,4-Benzothiadiazines |
| GB8328907D0 (en) * | 1983-10-28 | 1983-11-30 | Smith Kline French Lab | Chemical compounds |
-
1992
- 1992-05-22 ES ES92910342T patent/ES2111637T3/es not_active Expired - Lifetime
- 1992-05-22 KR KR1019930703587A patent/KR970002467B1/ko not_active Expired - Fee Related
- 1992-05-22 US US08/142,307 patent/US5401739A/en not_active Expired - Fee Related
- 1992-05-22 WO PCT/JP1992/000672 patent/WO1992020666A1/ja not_active Ceased
- 1992-05-22 CA CA002109723A patent/CA2109723C/en not_active Expired - Fee Related
- 1992-05-22 DE DE69223422T patent/DE69223422T2/de not_active Expired - Fee Related
- 1992-05-22 EP EP92910342A patent/EP0641789B1/en not_active Expired - Lifetime
- 1992-05-22 AU AU17923/92A patent/AU655986B2/en not_active Ceased
- 1992-05-22 DK DK92910342.2T patent/DK0641789T3/da active
- 1992-05-22 AT AT92910342T patent/ATE160776T1/de not_active IP Right Cessation
-
1995
- 1995-06-28 HU HU95P/P00488P patent/HU211585A9/hu unknown
-
1997
- 1997-12-16 GR GR970403318T patent/GR3025669T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GR3025669T3 (en) | 1998-03-31 |
| US5401739A (en) | 1995-03-28 |
| EP0641789A1 (en) | 1995-03-08 |
| WO1992020666A1 (fr) | 1992-11-26 |
| HU211585A9 (en) | 1995-12-28 |
| KR970002467B1 (ko) | 1997-03-05 |
| EP0641789A4 (en) | 1994-04-18 |
| DE69223422D1 (de) | 1998-01-15 |
| ATE160776T1 (de) | 1997-12-15 |
| AU1792392A (en) | 1992-12-30 |
| CA2109723A1 (en) | 1992-11-26 |
| EP0641789B1 (en) | 1997-12-03 |
| CA2109723C (en) | 1999-07-20 |
| AU655986B2 (en) | 1995-01-19 |
| ES2111637T3 (es) | 1998-03-16 |
| DE69223422T2 (de) | 1998-04-09 |
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