DK0516660T3 - Use of S-adenosylmethionine as a remedy for viral infections with retroviruses - Google Patents
Use of S-adenosylmethionine as a remedy for viral infections with retrovirusesInfo
- Publication number
- DK0516660T3 DK0516660T3 DK91903897.6T DK91903897T DK0516660T3 DK 0516660 T3 DK0516660 T3 DK 0516660T3 DK 91903897 T DK91903897 T DK 91903897T DK 0516660 T3 DK0516660 T3 DK 0516660T3
- Authority
- DK
- Denmark
- Prior art keywords
- adenosylmethionine
- retroviruses
- remedy
- viral infections
- bisulphate
- Prior art date
Links
- MEFKEPWMEQBLKI-AIRLBKTGSA-N S-adenosyl-L-methioninate Chemical compound O[C@@H]1[C@H](O)[C@@H](C[S+](CC[C@H](N)C([O-])=O)C)O[C@H]1N1C2=NC=NC(N)=C2N=C1 MEFKEPWMEQBLKI-AIRLBKTGSA-N 0.000 title abstract 2
- 208000036142 Viral infection Diseases 0.000 title 1
- 229960001570 ademetionine Drugs 0.000 title 1
- 241001430294 unidentified retrovirus Species 0.000 title 1
- 230000009385 viral infection Effects 0.000 title 1
- 208000030507 AIDS Diseases 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 210000004698 lymphocyte Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
In $i(in vitro) tests in lymphocyte cultures, S-adenosyl-L-methionine, stabilised as tosylate bisulphate, is effective against AIDS viruses with a half-concentration in the range of 100 to 200 $g(m)g/ml.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4005275A DE4005275A1 (en) | 1990-02-20 | 1990-02-20 | USE OF S-ADENOSYLMETHIONINE AS AGENTS AGAINST VIRAL INFECTIONS BY RETROVIRUS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0516660T3 true DK0516660T3 (en) | 1994-04-18 |
Family
ID=6400553
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91903897.6T DK0516660T3 (en) | 1990-02-20 | 1991-02-20 | Use of S-adenosylmethionine as a remedy for viral infections with retroviruses |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0516660B1 (en) |
| JP (1) | JPH05504355A (en) |
| AT (1) | ATE93141T1 (en) |
| CA (1) | CA2076377A1 (en) |
| DE (2) | DE4005275A1 (en) |
| DK (1) | DK0516660T3 (en) |
| WO (1) | WO1991012809A1 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5292773A (en) * | 1990-02-14 | 1994-03-08 | Hirsch Gerald P | Treating aids and HIV infection with methionine |
| IT1243859B (en) * | 1990-10-23 | 1994-06-28 | Bioresearch Spa | PHARMACEUTICAL COMPOSITIONS INCLUDING ASSOCIATIONS BETWEEN S-ADENOSYL-L-METHIONINE SALTS AND 5-METHYL (OR 5-FORMYL) -TETHYDROPHOLIC ACID FOR THE TREATMENT OF NEUROLOGICAL COMPLICATIONS IN AIDS SICKS. |
| DE19628514C1 (en) * | 1996-07-05 | 1997-09-25 | E Dr Grundmann | Synergistic inhibitor of HIV replication |
| DE19632823C1 (en) * | 1996-08-14 | 1997-11-20 | Symbio Herborn Group Gmbh & Co | Complexes of (+)-S-adenosyl-methionine and 3'-azido-2',3'-di:deoxy nucleoside compounds |
| WO2022261189A1 (en) * | 2021-06-09 | 2022-12-15 | Systamedic Inc. | Host directed drug combinations for treatment of viral infections |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ225906A (en) * | 1987-08-26 | 1990-10-26 | Merrell Dow Pharma | Aristeromycin/adenosine derivatives and pharmaceutical compositions |
-
1990
- 1990-02-20 DE DE4005275A patent/DE4005275A1/en not_active Withdrawn
-
1991
- 1991-02-20 JP JP3503985A patent/JPH05504355A/en active Pending
- 1991-02-20 DK DK91903897.6T patent/DK0516660T3/en active
- 1991-02-20 DE DE9191903897T patent/DE59100308D1/en not_active Expired - Fee Related
- 1991-02-20 WO PCT/EP1991/000319 patent/WO1991012809A1/en not_active Ceased
- 1991-02-20 EP EP91903897A patent/EP0516660B1/en not_active Expired - Lifetime
- 1991-02-20 AT AT91903897T patent/ATE93141T1/en not_active IP Right Cessation
- 1991-02-20 CA CA002076377A patent/CA2076377A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE4005275A1 (en) | 1991-08-22 |
| JPH05504355A (en) | 1993-07-08 |
| EP0516660A1 (en) | 1992-12-09 |
| WO1991012809A1 (en) | 1991-09-05 |
| CA2076377A1 (en) | 1991-08-21 |
| EP0516660B1 (en) | 1993-08-18 |
| ATE93141T1 (en) | 1993-09-15 |
| DE59100308D1 (en) | 1993-09-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2051641A1 (en) | PROCEDURES FOR THE PREPARATION OF THIOUREA-DERIVED COMPOUNDS. | |
| MD1224B2 (en) | Application of nucleoside analogues with 1,3-oxathiolan for treatment of hepatitis B | |
| DK224286D0 (en) | 2 ', 3'-dideoxy nucleosides | |
| ATE137242T1 (en) | COVALENT-THER LIPIDENUCLEOSIDE CONJUGATES | |
| ES2083668T5 (en) | ANTIVIRICAL COMBINATIONS CONTAINING NUCLEOSIDE ANALOGS. | |
| DK0497816T3 (en) | Treatment of HIV infections and compounds useful thereby | |
| DK0463540T3 (en) | "Antiviral agent" | |
| KR880003622A (en) | Catechol derivatives and agents for preventing and treating progression of central nervous system degenerative diseases containing them | |
| YU194691A (en) | BENZODIAZEPINONI | |
| FR2678271B1 (en) | PYRIMIDINE-4-CARBOXAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION. | |
| FI875544A7 (en) | Use of 3'-deoxythymidin-2'-ene (3'-deoxy-2',3'-didehydrothymidine) for the treatment of patients infected with retroviruses. | |
| TW371662B (en) | Antiviral acyclic phosphonomethoxyalkyl substituted alkenyl purine and pyrimidine derivatives | |
| DK0516660T3 (en) | Use of S-adenosylmethionine as a remedy for viral infections with retroviruses | |
| DK0541594T3 (en) | Cyclopentane derivatives, process for their preparation and pharmaceutical use of the derivatives | |
| DK0625158T3 (en) | Therapeutic nucleosides of the 2 ', 3'-dideoxy-3'-fluoropurine series | |
| DK0750616T3 (en) | Acid addition salts of 2,3,4,5-tetrahydro-1H-3-benzazapine compounds | |
| DE68900760D1 (en) | VIRUS INHIBITING NUCLEOSIDE MIXTURE. | |
| ATE113210T1 (en) | ANTIVIRAL COMPOSITIONS CONTAINING SULFOQUINOVOSYLGLYCEROL DERIVATIVES AND ANALOGUES THEREOF. | |
| DK0827964T3 (en) | S - (+) - adenosylmethionine and 3'-azido-2 ', 3'-dideoxynucleoside complexes as potent inhibitors of HIV replication | |
| ATE124050T1 (en) | CHIRAL 2-(PHOSPHONOMETHOXY)PROPYL-GUANINE AS ANTIVIRAL AGENTS. | |
| FI861934A0 (en) | NYA ISOXAZOLDERIVAT, FOERFARANDE FOER DERAS FRAMSTAELLNING OCH DESSA INNEHAOLLANDE FARMACEUTISKA PREPARAT. | |
| BR0109345A (en) | Compounds with anti-HIV activity | |
| DK0480391T3 (en) | Emulsifier-free emulsion polymers, their preparation and their use in extended-release pharmaceutical preparations | |
| ES2063147T3 (en) | ANTIVIRAL COMPOUNDS. | |
| DK410189A (en) | PHARMACEUTICAL PREPARATION FOR THE INHIBITION OF ANTI-VIRA INFECTION INFECTING AIDS |