DK0502054T3 - Aerosolfremstilling af glutathion og fremgangsmåde til forøgelse af glutathioninholdet i lunger - Google Patents
Aerosolfremstilling af glutathion og fremgangsmåde til forøgelse af glutathioninholdet i lungerInfo
- Publication number
- DK0502054T3 DK0502054T3 DK90917464.1T DK90917464T DK0502054T3 DK 0502054 T3 DK0502054 T3 DK 0502054T3 DK 90917464 T DK90917464 T DK 90917464T DK 0502054 T3 DK0502054 T3 DK 0502054T3
- Authority
- DK
- Denmark
- Prior art keywords
- glutathione
- lungs
- increasing
- aerosol preparation
- content
- Prior art date
Links
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 title abstract 6
- 108010024636 Glutathione Proteins 0.000 title abstract 4
- 210000004072 lung Anatomy 0.000 title abstract 3
- 229960003180 glutathione Drugs 0.000 title 2
- 239000000443 aerosol Substances 0.000 title 1
- 208000030507 AIDS Diseases 0.000 abstract 2
- 201000003883 Cystic fibrosis Diseases 0.000 abstract 2
- 201000009794 Idiopathic Pulmonary Fibrosis Diseases 0.000 abstract 2
- 230000003190 augmentative effect Effects 0.000 abstract 2
- 208000036971 interstitial lung disease 2 Diseases 0.000 abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
- A61K38/063—Glutathione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Dispersion Chemistry (AREA)
- Otolaryngology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/441,521 US5238683A (en) | 1989-11-24 | 1989-11-24 | Aerosol preparation of glutathione and a method for augmenting glutathione level in lungs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0502054T3 true DK0502054T3 (da) | 1995-06-06 |
Family
ID=23753204
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90917464.1T DK0502054T3 (da) | 1989-11-24 | 1990-11-23 | Aerosolfremstilling af glutathion og fremgangsmåde til forøgelse af glutathioninholdet i lunger |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US5238683A (da) |
| EP (1) | EP0502054B1 (da) |
| JP (1) | JPH0669957B2 (da) |
| AT (1) | ATE120087T1 (da) |
| AU (1) | AU631711B2 (da) |
| CA (1) | CA2069440A1 (da) |
| DE (1) | DE69018092T2 (da) |
| DK (1) | DK0502054T3 (da) |
| ES (1) | ES2069755T3 (da) |
| GR (1) | GR3015530T3 (da) |
| WO (1) | WO1991007997A1 (da) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6030950A (en) * | 1987-07-09 | 2000-02-29 | Ohlenschlaeger; Gerhard | Pharmaceutical therapeutic use of glutathione derivative |
| US5653685A (en) * | 1990-10-10 | 1997-08-05 | Lrt, Inc. | Method of providing circulation via lung expansion and deflation |
| USRE36460E (en) * | 1990-10-10 | 1999-12-21 | Life Science Holdings, Inc. | Method of providing circulation via lung expansion and deflation |
| US6180596B1 (en) | 1995-05-18 | 2001-01-30 | Wisconsin Alumni Research Foundation | Methods of inhibiting phospholipase A2 and phospholipase A2 stimulator activities |
| US5658877A (en) * | 1995-05-18 | 1997-08-19 | Wisconsin Alumni Research Foundation | Method to treat endotoxin effects by administration of 33 kilodalton phospholipid binding protein |
| AU713362B2 (en) * | 1996-03-08 | 1999-12-02 | Life Resuscitation Technologies, Inc. | Liquid ventilation method and apparatus |
| CA2276183C (en) * | 1996-12-31 | 2009-06-09 | Antioxidant Pharmaceuticals Corporation | Pharmaceutical preparations of glutathione and methods of administration thereof |
| US6896899B2 (en) * | 1996-12-31 | 2005-05-24 | Antioxidant Pharmaceuticals Corp. | Pharmaceutical preparations of glutathione and methods of administration thereof |
| DE69841217D1 (de) * | 1997-01-13 | 2009-11-19 | Univ Emory | Glutathion zur behandlung von influenzainfektionen |
| KR100585242B1 (ko) * | 1998-06-23 | 2006-12-05 | 교와 핫꼬 고교 가부시끼가이샤 | 인플루엔자감염증치료용화합물및조성물 |
| ES2247142T3 (es) | 2000-05-02 | 2006-03-01 | F. Hoffmann-La Roche Ag | Nuevos retinoides gamma selectivos. |
| US7179791B2 (en) * | 2001-01-11 | 2007-02-20 | Duke University | Inhibiting GS-FDH to modulate NO bioactivity |
| US7790762B2 (en) * | 2002-10-31 | 2010-09-07 | National Jewish Health | Compounds and methods for thiol-containing compound efflux and cancer treatment |
| US20040087527A1 (en) * | 2002-10-31 | 2004-05-06 | Day Brian J. | Methods for treatment of thiol-containing compound deficient conditions |
| US20080221029A1 (en) * | 2002-10-31 | 2008-09-11 | Regents Of The University Of Colorado | Methods for treatment of thiol-containing compound deficient conditions |
| JP5112876B2 (ja) * | 2004-11-07 | 2013-01-09 | エフ． ギルフォード ティモシー | 還元型グルタチオン経口投与のためのリポソーム処方物 |
| US20090068253A1 (en) * | 2005-09-06 | 2009-03-12 | Guilford F Timothy | Method for the treatment of infection with hhv-6 virus and the amelioration of symptoms related to virus using liposomal encapsulation for delivery of reduced glutathione |
| CA2925546C (en) | 2012-10-29 | 2022-06-14 | The University Of North Carolina At Chapel Hill | Methods and compositions for treating mucosal tissue disorders |
| US9913801B2 (en) * | 2013-02-15 | 2018-03-13 | Your Energy Systems, LLC | Treatment of evolving bacterial resistance diseases including Klebsiella pneumoniae with liposomally formulated glutathione |
| EP3541401A4 (en) | 2016-11-17 | 2020-07-29 | Renovion, Inc. | TREATMENT OF RESPIRATORY TRACT INFECTIONS AND DISEASES WITH GLUTATHION COMPOSITIONS |
| ES3008699T3 (en) | 2017-11-17 | 2025-03-24 | Renovion Inc | Stable ascorbic acid compositions and methods of using the same |
| US11344497B1 (en) | 2017-12-08 | 2022-05-31 | Quicksilver Scientific, Inc. | Mitochondrial performance enhancement nanoemulsion |
| US10722465B1 (en) | 2017-12-08 | 2020-07-28 | Quicksilber Scientific, Inc. | Transparent colloidal vitamin supplement |
| BR112021007692A2 (pt) * | 2018-10-23 | 2021-08-10 | George Edward Hoag | composição e método para tratar os pulmões |
| US11291702B1 (en) | 2019-04-15 | 2022-04-05 | Quicksilver Scientific, Inc. | Liver activation nanoemulsion, solid binding composition, and toxin excretion enhancement method |
| IT202000009553A1 (it) | 2020-04-30 | 2021-10-30 | Innbiotec Pharma S R L | Composizione farmaceutica di derivati del glutatione per l’uso nel trattamento di sindromi respiratorie |
| CN113252896B (zh) * | 2021-05-13 | 2022-08-09 | 四川大学华西医院 | 一款利用肺泡灌洗液中nd1预测急性呼吸窘迫综合征预后的试剂盒 |
| AU2023205178B2 (en) | 2022-01-04 | 2025-09-25 | Renovion, Inc. | Aqueous solution comprising a glutathione salt |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA909679A (en) * | 1972-09-12 | Calbiochem | Process of and composition for mucolysis | |
| BE788945A (da) * | 1971-09-20 | 1973-03-19 | Oreal | |
| US4424216A (en) * | 1979-07-31 | 1984-01-03 | The Rockefeller University | Method for the reduction of mucin viscosity |
| DK283180A (da) * | 1980-07-01 | 1982-01-02 | Novo Industri As | Polypeptider og derivater deraf |
| US4513005A (en) * | 1981-06-18 | 1985-04-23 | Lilly Industries Limited | SRS-A antagonists |
| IT1176983B (it) * | 1984-10-16 | 1987-08-26 | Zambon Spa | Dipeptidi ad attivita' farmacologica |
| GB8505285D0 (en) * | 1985-03-01 | 1985-04-03 | Beecham Group Plc | Compounds |
| US4710489A (en) * | 1985-04-22 | 1987-12-01 | Cornell Research Foundation, Inc. | Glutathione delivery system |
| JP2770970B2 (ja) * | 1987-04-09 | 1998-07-02 | フアイソンズ・ピーエルシー | ペンタミジンを含有する医薬組成物 |
-
1989
- 1989-11-24 US US07/441,521 patent/US5238683A/en not_active Expired - Lifetime
-
1990
- 1990-11-23 DE DE69018092T patent/DE69018092T2/de not_active Expired - Lifetime
- 1990-11-23 CA CA002069440A patent/CA2069440A1/en not_active Abandoned
- 1990-11-23 AU AU68857/91A patent/AU631711B2/en not_active Expired
- 1990-11-23 AT AT90917464T patent/ATE120087T1/de not_active IP Right Cessation
- 1990-11-23 EP EP90917464A patent/EP0502054B1/en not_active Expired - Lifetime
- 1990-11-23 ES ES90917464T patent/ES2069755T3/es not_active Expired - Lifetime
- 1990-11-23 JP JP3500599A patent/JPH0669957B2/ja not_active Expired - Fee Related
- 1990-11-23 DK DK90917464.1T patent/DK0502054T3/da active
- 1990-11-23 WO PCT/US1990/006825 patent/WO1991007997A1/en not_active Ceased
-
1991
- 1991-12-31 US US07/814,885 patent/US5989521A/en not_active Expired - Fee Related
-
1995
- 1995-03-23 GR GR940402884T patent/GR3015530T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0669957B2 (ja) | 1994-09-07 |
| GR3015530T3 (en) | 1995-06-30 |
| DE69018092T2 (de) | 1995-07-27 |
| EP0502054A1 (en) | 1992-09-09 |
| EP0502054A4 (en) | 1993-02-24 |
| US5989521A (en) | 1999-11-23 |
| ATE120087T1 (de) | 1995-04-15 |
| CA2069440A1 (en) | 1991-05-25 |
| DE69018092D1 (de) | 1995-04-27 |
| EP0502054B1 (en) | 1995-03-22 |
| WO1991007997A1 (en) | 1991-06-13 |
| US5238683A (en) | 1993-08-24 |
| AU631711B2 (en) | 1992-12-03 |
| AU6885791A (en) | 1991-06-26 |
| JPH05501263A (ja) | 1993-03-11 |
| ES2069755T3 (es) | 1995-05-16 |
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