DK0571253T3 - Benzimidazolderivater med antidiabetisk og antiblodpladekoagulerende virkning - Google Patents

Benzimidazolderivater med antidiabetisk og antiblodpladekoagulerende virkning

Info

Publication number: DK0571253T3
Authority: DK; Denmark
Prior art keywords: antidiabetic; benzimidazole derivatives; coagulant effect; platelet coagulant; platelet
Prior art date: 1992-05-19

Application number

DK93401239T

Other languages

English (en)

Inventor

Vera Alekseevna Anisimova

Margarita Valentinov Levchenko

Tatyana Borisovna Korochina

Alexander Alexeyevich Spasov

Sergei Gennadyevich Kovalev

Galina Petrovna Dudchenko

Original Assignee

Adir

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-05-19

Filing date

1993-05-14

Publication date

1999-07-19

1992-05-19 Priority claimed from FR9206036A external-priority patent/FR2691462B1/fr

1992-07-31 Priority claimed from FR9209488A external-priority patent/FR2694293B1/fr

1993-05-14 Application filed by Adir filed Critical Adir

1999-07-19 Application granted granted Critical

1999-07-19 Publication of DK0571253T3 publication Critical patent/DK0571253T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Diabetes (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
Hematology (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Obesity (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Plural Heterocyclic Compounds (AREA)

DK93401239T 1992-05-19 1993-05-14 Benzimidazolderivater med antidiabetisk og antiblodpladekoagulerende virkning DK0571253T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9206036A FR2691462B1 (fr)	1992-05-19	1992-05-19	Nouveaux derives du benzimidazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR9209488A FR2694293B1 (fr)	1992-07-31	1992-07-31	Nouveau dérivé du benzimidazole, son procédé de préparation et les compositions pharmaceutiques qui le contiennent.

Publications (1)

Publication Number	Publication Date
DK0571253T3 true DK0571253T3 (da)	1999-07-19

Family

ID=26229468

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK93401239T DK0571253T3 (da)	1992-05-19	1993-05-14	Benzimidazolderivater med antidiabetisk og antiblodpladekoagulerende virkning

Country Status (10)

Country	Link
US (2)	US5623073A (da)
EP (1)	EP0571253B1 (da)
JP (1)	JP2506263B2 (da)
AT (1)	ATE172975T1 (da)
AU (1)	AU656466B2 (da)
CA (1)	CA2096475A1 (da)
DE (1)	DE69321875T2 (da)
DK (1)	DK0571253T3 (da)
ES (1)	ES2126636T3 (da)
NZ (1)	NZ247643A (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2261208A1 (en)	1993-06-25	2010-12-15	Aventisub II Inc.	Intermediates for the preparation of antihistaminic 4-diphenylmethyl/diphenylmethoxy piperidine derivatives
US6147216A (en) *	1993-06-25	2000-11-14	Merrell Pharmaceuticals Inc.	Intermediates useful for the preparation of antihistaminic piperidine derivatives
AUPN236595A0 (en)	1995-04-11	1995-05-11	Rescare Limited	Monitoring of apneic arousals
FR2765223B1 (fr) *	1997-06-25	1999-08-27	Adir	Nouveaux derives tricycliques du benzimidazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US6683094B2 (en)	1998-07-02	2004-01-27	Aventis Pharmaceuticals Inc.	Antihistaminic piperidine derivatives and intermediates for the preparation thereof
US6930197B2 (en)	1998-07-02	2005-08-16	Aventis Pharmaceuticals Inc.	Antihistaminic piperidine derivatives and intermediates for the preparation thereof
RU2003126188A (ru) *	2001-01-26	2005-03-27	Бристол-Маерс Сквибб Компани (Us)	Имидазолильные производные как ингибиторы кортикотропин-рилизинг фактора
DE602005007215D1 (de) *	2004-05-14	2008-07-10	Cleveland Clinic Foundation	Kleinmolekülige hemmer für mrp1 und andere multiarzneimitteltransporter
PL2001892T3 (pl)	2006-03-17	2013-09-30	Ambit Biosciences Corp	Imidazolotiazolowe związki do leczenia chorób proliferacyjnych
KR20150104231A (ko) *	2007-09-19	2015-09-14	암비트 바이오사이언시즈 코포레이션	Ｎ-(5-ｔｅｒｔ-부틸-이속사졸-3-일)-Ｎ''-[4-[7-(2-모르폴린-4-일-에톡시)이미다조[2,1-Ｂ][1,3]벤조티아졸-2-일]페닐]우레아를 포함하는 고체 형태, 그의 조성물 및 그의 용도
RU2386634C2 (ru) *	2007-12-27	2010-04-20	Вера Алексеевна Анисимова	Средство гемореологическое, снижающее инсулинорезистентность и восстанавливающее толерантность организма к глюкозе, и фармацевтическая композиция на его основе
CA2719767A1 (en) *	2008-03-27	2009-10-01	Burnham Institute For Medical Research	Inhibitors of antigen receptor-induced nf-.kappa.b activation
GB0808947D0 (en) *	2008-05-16	2008-06-25	Shire Llc	Substituted quinazolines
GB0808968D0 (en) *	2008-05-16	2008-06-25	Shire Llc	Substitute quinazolines
GB0808952D0 (en) *	2008-05-16	2008-06-25	Shire Llc	Substituted quinazolines
GB0808967D0 (en) *	2008-05-16	2008-06-25	Shire Llc	Substitute quinazolines
RU2391345C2 (ru) *	2008-07-23	2010-06-10	Федеральное Государственное Образовательное Учреждение Высшего Профессионального Образования "Южный Федеральный Университет"	ДИГИДРОХЛОРИД 1-(3-МОРФОЛИНОПРОПИЛ)-2-ФЕНИЛИМИДАЗО[1,2-a]-БЕНЗИМИДАЗОЛА, ПРОЯВЛЯЮЩИЙ СВОЙСТВА АНТАГОНИСТА ПУРИНОВЫХ P2Y1-РЕЦЕПТОРОВ, АНТИАГРЕГАНТНУЮ И АНТИТРОМБОТИЧЕСКУЮ АКТИВНОСТЬ
JP6068464B2 (ja) *	2011-07-15	2017-01-25	ヤンセンファーマシューティカルズ，インコーポレーテッド	γ−セクレターゼ調節剤としての新規な置換インドール誘導体
DK3340796T3 (da)	2015-08-28	2021-07-26	Chdi Foundation Inc	Sonder til afbildning af huntingtin-protein
CN108250202B (zh) *	2018-01-15	2019-10-25	陕西师范大学	2,3-二取代苯并咪唑并[1,2-a]嘧啶类化合物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3732243A (en) *	1970-06-23	1973-05-08	Sankyo Co	2-(p-bromophenyl)-9-dimethyl-amino-propyl-9h-imidazo(1,2-a)benzimidazole
GB1476949A (en) *	1974-11-20	1977-06-16	Wyeth John & Brother Ltd	Imidazo-1,2-a-benzimidazole and pyrimido-1,2-a-benzimidazole derivatives their preparation and their pharmaceutical compositions
US5008282A (en) *	1988-12-28	1991-04-16	Kotobuki Seiyaku Co. Ltd.	Cyclic guanidine derivatives, anti-ulceratives and methods of manufacturing the same

1993
- 1993-05-14 DE DE69321875T patent/DE69321875T2/de not_active Expired - Fee Related
- 1993-05-14 ES ES93401239T patent/ES2126636T3/es not_active Expired - Lifetime
- 1993-05-14 DK DK93401239T patent/DK0571253T3/da active
- 1993-05-14 EP EP93401239A patent/EP0571253B1/fr not_active Expired - Lifetime
- 1993-05-14 AT AT93401239T patent/ATE172975T1/de active
- 1993-05-18 AU AU38608/93A patent/AU656466B2/en not_active Ceased
- 1993-05-18 CA CA002096475A patent/CA2096475A1/fr not_active Abandoned
- 1993-05-18 US US08/063,531 patent/US5623073A/en not_active Expired - Fee Related
- 1993-05-18 NZ NZ247643A patent/NZ247643A/en unknown
- 1993-05-18 JP JP5151016A patent/JP2506263B2/ja not_active Expired - Lifetime
1994
- 1994-10-28 US US08/330,903 patent/US5639756A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ATE172975T1 (de)	1998-11-15
DE69321875T2 (de)	1999-06-17
DE69321875D1 (de)	1998-12-10
US5639756A (en)	1997-06-17
ES2126636T3 (es)	1999-04-01
EP0571253A1 (fr)	1993-11-24
AU656466B2 (en)	1995-02-02
NZ247643A (en)	1995-07-26
AU3860893A (en)	1993-11-25
JP2506263B2 (ja)	1996-06-12
CA2096475A1 (fr)	1993-11-20
EP0571253B1 (fr)	1998-11-04
JPH0687859A (ja)	1994-03-29
US5623073A (en)	1997-04-22

Publication	Publication Date	Title
DK0571253T3 (da)	1999-07-19	Benzimidazolderivater med antidiabetisk og antiblodpladekoagulerende virkning
IS4185A (is)	1994-12-29	Hliðstæð aðferð til framleiðslu fenýlsúlfonylamino-pýrimidines afleiða
ATE18902T1 (de)	1986-04-15	Aminosaeurederivate und ihre therapeutischen verwendungen.
FI914928A0 (fi)	1991-10-18	Hydroximetyl (metylencyklopentyl) puriner och -pyrimidiner.
TR199501253A2 (tr)	1996-06-21	Amino(tio) eter türevleri.
YU101791A (sh)	1997-08-22	Supstituisani ftalidi i heterociklični ftalidi
NZ233735A (en)	1992-10-28	Heterocyclic substituted aminophenol derivatives
NO179834C (no)	1996-12-27	Substituerte cykloheksanderivater og anvendelse av forbindelsene for fremstilling av legemidler
FI932105A0 (fi)	1993-05-10	Sulfonylbensylsubstituerade benso- och pyridopyridoner
NZ240575A (en)	1993-07-27	N-benzoylproline derivatives and pharmaceutical compositions
DE69115526D1 (de)	1996-02-01	2,4-Pyrimidindionderivate und diese enthaltende Arzneimittel
FI892675A0 (fi)	1989-06-01	2,6-dihalogenpyridin-3 -karboxylsyraderivat och deras framstaellning.
IT1270975B (it)	1997-05-26	Composti piperidin-triazinici atti all'impiego come stabilizzanti allaluce, al calore e alla ossidazione per materiali organici
NO306116B1 (no)	1999-09-20	Ny benzotiadiazinforbindelse og farmasöytiske sammensetninger
DE58905079D1 (de)	1993-09-09	Neue alpha-aminocarbonsaeure-derivate, ihre herstellung und verwendung.
DK0617035T3 (da)	1998-07-27	Hetero-tricyclisk-substituerede phenyl-cyclohexan-carboxylsyrederivater.
ES2123728T3 (es)	1999-01-16	Derivados de pirrolo-pirazina de actividad 5-ht3.
DK0625520T3 (da)	2000-01-31	Thiazolotriazol- og thiazolodiazolderivater med fungicid aktivitet
DE59106215D1 (de)	1995-09-14	Substituierte Aminosäureamid-Derivate, deren Herstellung und Verwendung.
IT1263892B (it)	1996-09-05	Composti piperidin-triazinici atti all'impiego come stabilizzanti per materiali organici
ATE123025T1 (de)	1995-06-15	2-amino-n-(((4-(aminocarbonyl)pyrimidin-2- yl>amino>alkyl>-pyrimidin-4- carbonsäureamidderivate, ihre herstellung und ihre anwendung in der therapeutica.
DE59105160D1 (de)	1995-05-18	Substituierte Aminosäureamid-Derivate deren Herstellung und Verwendung.
DK0552631T3 (da)	1998-05-11	Alfa-Aryl-alfa-hydroxy-beta-imidazolinyl-propionsyreamider
DK0483063T3 (da)	1994-11-14	Ergolinderivater
ES2061182T3 (es)	1994-12-01	2-fluoroneplanocina a y su fabricacion.