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DK0552373T3 - Apoptoseregulator - Google Patents

Apoptoseregulator

Info

Publication number
DK0552373T3
DK0552373T3 DK92914177T DK92914177T DK0552373T3 DK 0552373 T3 DK0552373 T3 DK 0552373T3 DK 92914177 T DK92914177 T DK 92914177T DK 92914177 T DK92914177 T DK 92914177T DK 0552373 T3 DK0552373 T3 DK 0552373T3
Authority
DK
Denmark
Prior art keywords
apoptosis regulator
apoptosis
regulator
Prior art date
Application number
DK92914177T
Other languages
Danish (da)
English (en)
Inventor
Satoru Nakai
Masakazu Adachi
Koutoku Aihara
Hitomi Mori
Michiaki Tominaga
Hiroyuki Ichikawa
Seiji Akamatsu
Fumio Saito
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Application granted granted Critical
Publication of DK0552373T3 publication Critical patent/DK0552373T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK92914177T 1991-07-03 1992-07-02 Apoptoseregulator DK0552373T3 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP16258791 1991-07-03
JP3346992 1992-02-20
JP4571892 1992-03-03
JP10058592 1992-03-25
PCT/JP1992/000841 WO1993000902A1 (fr) 1991-07-03 1992-07-02 Regulateur d'apoptose

Publications (1)

Publication Number Publication Date
DK0552373T3 true DK0552373T3 (da) 1999-12-27

Family

ID=27459795

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92914177T DK0552373T3 (da) 1991-07-03 1992-07-02 Apoptoseregulator

Country Status (11)

Country Link
US (5) US5672603A (fr)
EP (1) EP0552373B1 (fr)
KR (1) KR100196368B1 (fr)
AU (1) AU648690B2 (fr)
CA (1) CA2090876A1 (fr)
DE (1) DE69230131T2 (fr)
DK (1) DK0552373T3 (fr)
ES (1) ES2138971T3 (fr)
MX (1) MX9203950A (fr)
TW (1) TW229157B (fr)
WO (1) WO1993000902A1 (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994004504A1 (fr) * 1992-08-19 1994-03-03 Otsuka Pharmaceutical Co., Ltd. Regulateur d'apoptose
WO1994020107A1 (fr) * 1993-03-02 1994-09-15 Otsuka Pharmaceutical Co., Ltd. Inhibiteur de rejet pour transplantations et inhibiteur de production d'interleukine 1
GB9311132D0 (en) * 1993-05-28 1993-07-14 Eisai London Res Lab Ltd Control of cell death
ATE184793T1 (de) * 1993-10-21 1999-10-15 Otsuka Pharma Co Ltd Die verwendung von carbostyrilderivaten zur herstellung eines arzneimittels zur hemmung der produktion von interleukin-8
US5504093A (en) * 1994-08-01 1996-04-02 Otsuka Pharmaceutical Co., Ltd. Method for inhibiting nucleoside and nucleobase transport in mammalian cells, and method for inhibition of DNA virus replication
MX9603868A (es) * 1995-01-11 1997-03-29 Otsuka Pharma Co Ltd Composicion farmaceutica de derivados de indeno para la regulacion de la apoptosis.
WO1998046229A1 (fr) * 1995-06-21 1998-10-22 Otsuka Pharmaceutical Co., Ltd. Inhibiteurs de la production d'il-8 et du mcaf
JPH0971532A (ja) * 1995-09-06 1997-03-18 Otsuka Pharmaceut Co Ltd 発癌抑制剤
US5700803A (en) * 1995-12-12 1997-12-23 Otsuka Pharmaceutical Co., Ltd. Method for reducing infarct size in subjects afflicted with ischemic heart disease
AU6854398A (en) * 1997-04-25 1998-11-24 Otsuka Pharmaceutical Co., Ltd. Hyaluronate synthesis inhibitors
US6008209A (en) * 1997-04-28 1999-12-28 Hoffmann-La Roche Inc. Method of using vitamin D3 analogs with bis C-20 side chains
WO1999015179A1 (fr) * 1997-09-25 1999-04-01 Regents Of The University Of Minnesota Procedes pour limiter l'apoptose des cellules
US6281191B1 (en) 1997-12-29 2001-08-28 Vladimir I. Slesarev Compositions and methods for treating hepatitis-C
FR2774289B1 (fr) 1998-02-03 2002-05-24 Goemar Lab Sa Medicament pour le traitement des dereglements de l'apoptose
DK1520588T3 (en) 1998-07-13 2015-03-23 Univ Texas Use of antibodies to aminophospholipids for cancer treatment
EP1234585A3 (fr) 1998-09-04 2004-01-21 The Regents Of The University Of Michigan Compositions pour la prévention ou le traitement du cancer
US6277974B1 (en) 1999-12-14 2001-08-21 Cogent Neuroscience, Inc. Compositions and methods for diagnosing and treating conditions, disorders, or diseases involving cell death
US20030044413A1 (en) * 2000-08-15 2003-03-06 Regents Of The University Of Minnesota Methods of limiting apoptosis of cells
AU2002360665A1 (en) * 2001-12-20 2003-07-09 Cogent Neuroscience, Inc. Methods for treating conditions, disorders, or diseases involving cell death
SI2269656T1 (sl) 2002-07-15 2014-11-28 Board Of Regents, The University Of Texas System Izbrana protitelesa, ki se veĹľejo na aminofosfolipide, in njihova uporaba v zdravljanju raka
JP2006510740A (ja) * 2002-11-07 2006-03-30 リージェンツ オブ ザ ユニバーシティ オブ ミネソタ 出血と関連した神経系障害を治療する方法
US20060204481A1 (en) * 2003-04-02 2006-09-14 Steer Clifford J Methods of promoting cell viability
CN1953743B (zh) 2004-01-22 2010-12-08 迈阿密大学 局部辅酶q10制剂及其使用方法
EP1871385A1 (fr) * 2005-02-10 2008-01-02 Regents Of The University Of Minnesota Procedes de traitement de troubles visuels
EP2136831B1 (fr) 2007-03-02 2012-09-12 The Cleveland Clinic Foundation Peptides anti-angiogéniques
JP5809415B2 (ja) 2007-11-09 2015-11-10 ペレグリン ファーマシューティカルズ，インコーポレーテッド 抗ｖｅｇｆ抗体の組成物および方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5430184A (en) * 1977-08-10 1979-03-06 Otsuka Pharmaceut Co Ltd 3,4-dihydrocarbostyril derivative
JPS6038384B2 (ja) * 1978-03-24 1985-08-31 大塚製薬株式会社 チオセミカルバゾン誘導体
JPS5777676A (en) * 1980-10-31 1982-05-15 Otsuka Pharmaceut Co Ltd Carbostyril derivative
JPS5793962A (en) * 1980-12-01 1982-06-11 Otsuka Pharmaceut Co Ltd Carbostyryl derivative
JPS62135423A (ja) * 1985-12-09 1987-06-18 Otsuka Pharmaceut Co Ltd 低酸素症改善剤

Also Published As

Publication number Publication date
ES2138971T3 (es) 2000-02-01
US5925640A (en) 1999-07-20
TW229157B (fr) 1994-09-01
MX9203950A (es) 1993-05-01
CA2090876A1 (fr) 1993-01-04
EP0552373A1 (fr) 1993-07-28
EP0552373A4 (en) 1993-09-22
DE69230131T2 (de) 2000-03-02
US5916890A (en) 1999-06-29
US5798358A (en) 1998-08-25
HK1004469A1 (en) 1998-11-27
AU2231792A (en) 1993-02-11
KR100196368B1 (ko) 1999-06-15
DE69230131D1 (de) 1999-11-18
AU648690B2 (en) 1994-04-28
KR930702002A (ko) 1993-09-08
US5672603A (en) 1997-09-30
EP0552373B1 (fr) 1999-10-13
WO1993000902A1 (fr) 1993-01-21
US5872120A (en) 1999-02-16

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