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DK0435177T3 - 4-Benzyl-5-phenyl-2,4-dihydro-3H-1,2,4-triazol-3-oner samt deres anvendelse som antikonvulsive midler - Google Patents

4-Benzyl-5-phenyl-2,4-dihydro-3H-1,2,4-triazol-3-oner samt deres anvendelse som antikonvulsive midler

Info

Publication number
DK0435177T3
DK0435177T3 DK90124971.4T DK90124971T DK0435177T3 DK 0435177 T3 DK0435177 T3 DK 0435177T3 DK 90124971 T DK90124971 T DK 90124971T DK 0435177 T3 DK0435177 T3 DK 0435177T3
Authority
DK
Denmark
Prior art keywords
anticonvulsants
triazol
dihydro
benzyl
ones
Prior art date
Application number
DK90124971.4T
Other languages
English (en)
Inventor
John M Kane
Francis P Miller
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Application granted granted Critical
Publication of DK0435177T3 publication Critical patent/DK0435177T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12—Oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK90124971.4T 1989-12-20 1990-12-20 4-Benzyl-5-phenyl-2,4-dihydro-3H-1,2,4-triazol-3-oner samt deres anvendelse som antikonvulsive midler DK0435177T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/453,440 US4966909A (en) 1989-12-20 1989-12-20 4-benzyl-5-phenyl-2,4-dihydro-3H-1,2,4-triazol-3-ones and their use as anticonvulsants

Publications (1)

Publication Number Publication Date
DK0435177T3 true DK0435177T3 (da) 1994-11-21

Family

ID=23800598

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90124971.4T DK0435177T3 (da) 1989-12-20 1990-12-20 4-Benzyl-5-phenyl-2,4-dihydro-3H-1,2,4-triazol-3-oner samt deres anvendelse som antikonvulsive midler

Country Status (12)

Country Link
US (1) US4966909A (da)
EP (1) EP0435177B1 (da)
JP (1) JP2968053B2 (da)
KR (1) KR0154529B1 (da)
AT (1) ATE113591T1 (da)
AU (1) AU634003B2 (da)
DE (1) DE69013871T2 (da)
DK (1) DK0435177T3 (da)
ES (1) ES2066096T3 (da)
IE (1) IE64989B1 (da)
PH (1) PH27352A (da)
ZA (1) ZA9010080B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4966909A (en) * 1989-12-20 1990-10-30 Merrell Dow Pharmaceuticals 4-benzyl-5-phenyl-2,4-dihydro-3H-1,2,4-triazol-3-ones and their use as anticonvulsants
SE470120B (sv) * 1992-04-03 1993-11-08 Whirlpool Int Förfarande för styrning av mikrovågsenergin i en mikrovågsugn och mikrovågsugn för genomförande av förfarandet
CA2216787C (en) * 1995-04-20 2001-05-22 Hoechst Marion Roussel, Inc. 3-phenyl-1,4-dialkyl-1,2,4-triazolium salts and their use as antidepressants
TW467902B (en) * 1996-07-31 2001-12-11 Bristol Myers Squibb Co Diphenyl heterocycles as potassium channel modulators
WO2000007999A1 (en) * 1998-08-03 2000-02-17 Sumitomo Chemical Company, Limited Triazolone derivatives, use thereof, and intermediate therefor
US6156775A (en) * 1999-03-01 2000-12-05 Novartis Ag Use of fluorinated triazoles in treating affective and attention disorders
TW200505441A (en) 2003-03-24 2005-02-16 Hoffmann La Roche Non-nucleoside reverse transcriptase inhibitorsⅠ
US7400548B2 (en) * 2005-02-09 2008-07-15 International Business Machines Corporation Method for providing multiple reads/writes using a 2read/2write register file array
WO2008119662A1 (en) 2007-03-29 2008-10-09 F. Hoffmann-La Roche Ag Non-nucleoside reverse transcriptase inhibitors
JP7698989B2 (ja) 2021-06-10 2025-06-26 Ｔｍｔマシナリー株式会社 紡糸引取装置

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1126882B (de) * 1960-05-03 1962-04-05 Boehringer Sohn Ingelheim Verfahren zur Herstellung von 1,2,4-Triazolonen-(5)
BE621842A (da) * 1962-08-27
GB1068083A (en) * 1964-04-02 1967-05-10 Philippe Gold Aubert í¸-1,2,4-triazolone-(5) derivatives
US3621099A (en) * 1969-03-05 1971-11-16 Charles R Jacobson Therapeutic compositions and methods for stimulating the central nervous system
DE3173083D1 (en) * 1980-03-22 1986-01-16 Fbc Ltd Pesticidal heterocyclic compounds, processes for preparing them, compositions containing them, and their use
DD153953A3 (de) * 1980-04-01 1982-02-17 Gottfried Schuster Mittel zur chemotherapie von virosen der kulturpflanzen
DD160447A1 (de) * 1981-03-26 1983-08-03 Johannes Dost Herbizide mittel, die 1,2,4-triazolinone-(5) enthalten
BE894856A (fr) * 1982-10-28 1983-02-14 Fahlberg List Veb Compositions herbicides a base d'un derive de la 1,2,4-triazolinone-(5)
JP2593084B2 (ja) * 1986-12-19 1997-03-19 メレルダウファーマスーティカルズ インコーポレーテッド ５−アリールー３ｈ−１，２，４−トリアゾールー３−オン類の神経変性障害の処置への用途
PH24094A (en) * 1986-12-19 1990-03-05 Merrell Dow Pharma 5-aryl-3h-1,2,4-triazol-3-ones and their use as anticonvulsants
US4966909A (en) * 1989-12-20 1990-10-30 Merrell Dow Pharmaceuticals 4-benzyl-5-phenyl-2,4-dihydro-3H-1,2,4-triazol-3-ones and their use as anticonvulsants

Also Published As

Publication number Publication date
DE69013871T2 (de) 1995-03-09
ZA9010080B (en) 1991-10-30
DE69013871D1 (de) 1994-12-08
EP0435177B1 (en) 1994-11-02
IE904599A1 (en) 1991-07-03
EP0435177A2 (en) 1991-07-03
IE64989B1 (en) 1995-09-20
ATE113591T1 (de) 1994-11-15
JP2968053B2 (ja) 1999-10-25
US4966909A (en) 1990-10-30
AU6808190A (en) 1991-06-27
PH27352A (en) 1993-06-21
KR0154529B1 (ko) 1998-11-16
JPH04128271A (ja) 1992-04-28
EP0435177A3 (en) 1992-01-08
KR910011807A (ko) 1991-08-07
ES2066096T3 (es) 1995-03-01
AU634003B2 (en) 1993-02-11

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