DK0411734T3 - Antigestagene 11beta-aryl-16alfa,17alfa-cyklohexano-østra-4,9-diener - Google Patents
Antigestagene 11beta-aryl-16alfa,17alfa-cyklohexano-østra-4,9-dienerInfo
- Publication number
- DK0411734T3 DK0411734T3 DK90250200.4T DK90250200T DK0411734T3 DK 0411734 T3 DK0411734 T3 DK 0411734T3 DK 90250200 T DK90250200 T DK 90250200T DK 0411734 T3 DK0411734 T3 DK 0411734T3
- Authority
- DK
- Denmark
- Prior art keywords
- cyclohexano
- dienes
- aryl
- 16alpha
- 11beta
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 125000002816 methylsulfanyl group Chemical group [H]C([H])([H])S[*] 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000006413 ring segment Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
- C07J53/002—Carbocyclic rings fused
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DD89331478A DD289541A5 (de) | 1989-08-04 | 1989-08-04 | Verfahren zur herstellung von 11beta-aryl-16 alpha, 17 alph-cyclohexanoestra-4,9-dienen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0411734T3 true DK0411734T3 (da) | 1994-08-29 |
Family
ID=5611394
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90250200.4T DK0411734T3 (da) | 1989-08-04 | 1990-08-06 | Antigestagene 11beta-aryl-16alfa,17alfa-cyklohexano-østra-4,9-diener |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5166199A (da) |
| EP (1) | EP0411734B1 (da) |
| JP (1) | JP3061856B2 (da) |
| AT (1) | ATE105298T1 (da) |
| DD (1) | DD289541A5 (da) |
| DE (1) | DE59005593D1 (da) |
| DK (1) | DK0411734T3 (da) |
| ES (1) | ES2053090T3 (da) |
| WO (1) | WO1991001993A1 (da) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6900193B1 (en) * | 1996-05-01 | 2005-05-31 | The United States Of America As Represented By The Department Of Health And Human Services | Structural modification of 19-norprogesterone I: 17-α-substituted-11-β-substituted-4-aryl and 21-substituted 19-norpregnadienedione as new antiprogestational agents |
| WO1997041145A1 (en) * | 1996-05-01 | 1997-11-06 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | 21-substituted progesterone derivatives as new antiprogestational agents |
| DE19649984A1 (de) * | 1996-11-22 | 1998-05-28 | Schering Ag | Cycloalkylsteroide, Verfahren zu ihrer Herstellung, diese Cycloalkylsteroide enthaltende pharmazeutische Präparate sowie deren Verwendung zur Herstellung von Arzneimitteln |
| US6483580B1 (en) | 1998-03-06 | 2002-11-19 | Kla-Tencor Technologies Corporation | Spectroscopic scatterometer system |
| US20060111577A1 (en) * | 2003-02-28 | 2006-05-25 | Kim Hyun K | Method for preparing 17 alpha-acetoxy-11beta-(4-n,n-dimethylaminophenyl)-19-norpregna-4,9-diene-3,20-dione, intermediates thereof, and methods for the preparation of such intermediates |
| PL2576582T3 (pl) | 2010-05-26 | 2020-06-29 | Corcept Therapeutics, Inc. | Leczenie dystrofii mięśniowej |
| US8722940B2 (en) | 2012-03-01 | 2014-05-13 | Saudi Basic Industries Corporation | High molybdenum mixed metal oxide catalysts for the production of unsaturated aldehydes from olefins |
| CA2977591C (en) | 2015-03-02 | 2024-09-10 | Corcept Therapeutics Inc | Use of glucocorticoid receptor antagonist and somatostatin analogues to treat acth-secreting tumors |
| ES2906778T3 (es) | 2015-03-30 | 2022-04-20 | Corcept Therapeutics Inc | Uso de antagonistas del receptor de glucocorticoides en combinación con glucocorticoides para tratar la insuficiencia suprarrenal |
| MX383318B (es) | 2015-08-13 | 2025-03-13 | Corcept Therapeutics Inc | Metodo para diagnosticar de manera diferencial el sindrome de cushing dependiente de la corticotropina. |
| CA3011728A1 (en) | 2016-01-19 | 2017-07-27 | Corcept Therapeutics, Inc. | Differential diagnosis of ectopic cushing's syndrome |
| KR102342620B1 (ko) | 2017-03-31 | 2021-12-22 | 코어셉트 쎄라퓨틱스 인코포레이티드 | 자궁경부암을 치료하기 위한 글루코코르티코이드 수용체 조정제 |
| US11213526B2 (en) | 2017-06-20 | 2022-01-04 | Corcept Therapeutics, Inc. | Methods of treating neuroepithelial tumors using selective glucocorticoid receptor modulators |
| JP2024500748A (ja) | 2020-12-18 | 2024-01-10 | インスティル バイオ （ユーケイ） リミテッド | 腫瘍浸潤リンパ球の処理 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2269350B1 (da) * | 1974-04-30 | 1978-06-30 | Inst Orch Khim | |
| DD251142A1 (de) * | 1984-11-29 | 1987-11-04 | Akad Wissenschaften Ddr | Verfahren zur herstellung von 16 alpha, 17 alpha-cyclohexano-17 beta-acetylgonen-3-onen |
| DE3708942A1 (de) * | 1987-03-18 | 1988-09-29 | Schering Ag | 19,11ss-ueberbrueckte steroide, deren herstellung und diese enthaltende pharmazeutische praeparate |
| DD277685A1 (de) * | 1988-12-05 | 1990-04-11 | Adw Ddr | Verfahren zur herstellung von 16 alpha, 17 alpha -cyxlohexano-estra- 4,9-dien-3-onen |
| DD277684A1 (de) * | 1988-12-05 | 1990-04-11 | Adw Ddr | Verfahren zur herstellung von 16 alpha, 17 alpha -carbocyclischen estr-4-en-3-onen |
-
1989
- 1989-08-04 DD DD89331478A patent/DD289541A5/de unknown
-
1990
- 1990-08-06 WO PCT/DE1990/000612 patent/WO1991001993A1/de not_active Ceased
- 1990-08-06 DK DK90250200.4T patent/DK0411734T3/da active
- 1990-08-06 JP JP02515071A patent/JP3061856B2/ja not_active Expired - Fee Related
- 1990-08-06 ES ES90250200T patent/ES2053090T3/es not_active Expired - Lifetime
- 1990-08-06 AT AT9090250200T patent/ATE105298T1/de not_active IP Right Cessation
- 1990-08-06 DE DE59005593T patent/DE59005593D1/de not_active Expired - Fee Related
- 1990-08-06 EP EP90250200A patent/EP0411734B1/de not_active Expired - Lifetime
- 1990-08-15 US US07/567,362 patent/US5166199A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPH05509289A (ja) | 1993-12-22 |
| EP0411734A1 (de) | 1991-02-06 |
| WO1991001993A1 (de) | 1991-02-21 |
| EP0411734B1 (de) | 1994-05-04 |
| ES2053090T3 (es) | 1994-07-16 |
| US5166199A (en) | 1992-11-24 |
| JP3061856B2 (ja) | 2000-07-10 |
| ATE105298T1 (de) | 1994-05-15 |
| DE59005593D1 (de) | 1994-06-09 |
| DD289541A5 (de) | 1991-05-02 |
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