DK0411158T3 - Fremgangsmåde til fremstilling af nucleosider ved anvendelse af phosphorylaser, der er opnåelige fra Bacillus stearothermophilus - Google Patents
Fremgangsmåde til fremstilling af nucleosider ved anvendelse af phosphorylaser, der er opnåelige fra Bacillus stearothermophilusInfo
- Publication number
- DK0411158T3 DK0411158T3 DK90903422.5T DK90903422T DK0411158T3 DK 0411158 T3 DK0411158 T3 DK 0411158T3 DK 90903422 T DK90903422 T DK 90903422T DK 0411158 T3 DK0411158 T3 DK 0411158T3
- Authority
- DK
- Denmark
- Prior art keywords
- donor
- phosphorylases
- nucleosides
- available
- preparation
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000002777 nucleoside Substances 0.000 title abstract 2
- 241000193385 Geobacillus stearothermophilus Species 0.000 title 1
- 102000009097 Phosphorylases Human genes 0.000 title 1
- 108010073135 Phosphorylases Proteins 0.000 title 1
- 125000003835 nucleoside group Chemical group 0.000 title 1
- OQRXBXNATIHDQO-UHFFFAOYSA-N 6-chloropyridine-3,4-diamine Chemical compound NC1=CN=C(Cl)C=C1N OQRXBXNATIHDQO-UHFFFAOYSA-N 0.000 abstract 3
- 102100036286 Purine nucleoside phosphorylase Human genes 0.000 abstract 3
- 108010009099 nucleoside phosphorylase Proteins 0.000 abstract 3
- 230000002255 enzymatic effect Effects 0.000 abstract 2
- 241000193830 Bacillus <bacterium> Species 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 abstract 1
- 229930182474 N-glycoside Natural products 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 150000003833 nucleoside derivatives Chemical class 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/38—Nucleosides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/07—Bacillus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/832—Bacillus
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4878589 | 1989-02-28 | ||
| JP20355689 | 1989-08-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0411158T3 true DK0411158T3 (da) | 1996-06-17 |
Family
ID=26389109
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90903422.5T DK0411158T3 (da) | 1989-02-28 | 1990-02-27 | Fremgangsmåde til fremstilling af nucleosider ved anvendelse af phosphorylaser, der er opnåelige fra Bacillus stearothermophilus |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US5258301A (fr) |
| EP (1) | EP0411158B1 (fr) |
| JP (1) | JP2795748B2 (fr) |
| KR (1) | KR970010134B1 (fr) |
| AT (1) | ATE138689T1 (fr) |
| AU (1) | AU631607B2 (fr) |
| CA (1) | CA2028119C (fr) |
| DE (1) | DE69027154T2 (fr) |
| DK (1) | DK0411158T3 (fr) |
| ES (1) | ES2089010T3 (fr) |
| WO (1) | WO1990010080A1 (fr) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2795748B2 (ja) * | 1989-02-28 | 1998-09-10 | ヤマサ醤油株式会社 | ヌクレオシドの製造法 |
| RS49561B (sr) * | 1993-12-14 | 2007-04-10 | Galenika A.D., | Postupak za enzimsku sintezu triazolo nukleozida primenom termofilnih bakterija |
| US5547857A (en) * | 1994-04-18 | 1996-08-20 | Ajinomoto Co., Inc. | Process for producing 5-methyluridine and purification by sedimentation velocity |
| AU4980097A (en) * | 1996-10-21 | 1998-05-15 | University Of Iowa Research Foundation, The | Efficient synthesis of nucleosides |
| JP3864357B2 (ja) * | 1997-08-04 | 2006-12-27 | 有機合成薬品工業株式会社 | プリンヌクレオシド化合物の製造方法 |
| JP3799784B2 (ja) * | 1997-11-14 | 2006-07-19 | 味の素株式会社 | 2,6−ジアミノプリン−2’−デオキシリボシドおよび2’−デオキシグアノシンの製造法 |
| KR20020048930A (ko) | 1999-08-20 | 2002-06-24 | 로셰 디아그노스틱스 게엠베하 | 데옥시리보뉴클레오시드의 효소적 합성 |
| RU2179188C2 (ru) * | 2000-03-03 | 2002-02-10 | Институт биоорганической химии им. М.М. Шемякина и Ю.А. Овчинникова РАН | СПОСОБ ПОЛУЧЕНИЯ РЕКОМБИНАНТНОЙ ПУРИННУКЛЕОЗИД-ФОСФОРИЛАЗЫ, РЕКОМБИНАНТНАЯ ПЛАЗМИДНАЯ ДНК pERPUPHO1 И ШТАММ ESCHERICHIA COLI BL21(DE3)/pERPUPHO1 ДЛЯ ЕГО ОСУЩЕСТВЛЕНИЯ |
| JP4066121B2 (ja) | 2000-03-27 | 2008-03-26 | 有機合成薬品工業株式会社 | グアノシン類及びその中間体の製造方法 |
| CA2380804A1 (fr) * | 2001-05-01 | 2002-11-01 | Mitsui Chemicals, Inc. | Methode pour la production de composes nucleosidiques a base de cytosine |
| KR101818564B1 (ko) * | 2016-03-21 | 2018-01-15 | 에스티팜 주식회사 | 바실러스 유래 뉴클레오시드 포스포릴라아제 및 락토코쿠스 유래 아데노신 디아미나아제를 이용한 3'-아미노-2',3'-디데옥시구아노신의 제조 방법 |
| KR101818561B1 (ko) * | 2016-03-21 | 2018-01-15 | 에스티팜 주식회사 | 바실러스 유래 뉴클레오시드 포스포릴라아제를 이용한 3'-아미노-2',3'-디데옥시아데노신의 제조 방법 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS56148289A (en) * | 1980-04-18 | 1981-11-17 | Unitika Ltd | Preparation of heat-resistant polynucleotide phosphorylase |
| CA1156573A (fr) * | 1980-04-18 | 1983-11-08 | Hiroshi Nakajima | Souche uk 788 et methode de production d'un enzyme utile |
| JPS57146593A (en) * | 1981-03-09 | 1982-09-10 | Ajinomoto Co Inc | Preparation of ribofuranosyltriazole derivative |
| JPS58170493A (ja) * | 1982-04-01 | 1983-10-07 | Yamasa Shoyu Co Ltd | 3′−デオキシグアノシンの製造法 |
| US4614719A (en) * | 1982-04-30 | 1986-09-30 | Yamasa Shoyu Kabushiki Kaisha | Process for producing ribavirin |
| JP2547438B2 (ja) * | 1988-06-22 | 1996-10-23 | 日本たばこ産業株式会社 | ヌクレオシド化合物の製造方法 |
| JP2795748B2 (ja) * | 1989-02-28 | 1998-09-10 | ヤマサ醤油株式会社 | ヌクレオシドの製造法 |
| JP3080771B2 (ja) * | 1992-04-17 | 2000-08-28 | ユニチカ株式会社 | ジヌクレオシドポリリン酸又はその誘導体の製造方法 |
-
1990
- 1990-02-27 JP JP2503654A patent/JP2795748B2/ja not_active Expired - Fee Related
- 1990-02-27 DK DK90903422.5T patent/DK0411158T3/da active
- 1990-02-27 WO PCT/JP1990/000240 patent/WO1990010080A1/fr not_active Ceased
- 1990-02-27 CA CA002028119A patent/CA2028119C/fr not_active Expired - Lifetime
- 1990-02-27 EP EP90903422A patent/EP0411158B1/fr not_active Expired - Lifetime
- 1990-02-27 KR KR1019900702343A patent/KR970010134B1/ko not_active Expired - Fee Related
- 1990-02-27 ES ES90903422T patent/ES2089010T3/es not_active Expired - Lifetime
- 1990-02-27 AT AT90903422T patent/ATE138689T1/de active
- 1990-02-27 DE DE69027154T patent/DE69027154T2/de not_active Expired - Lifetime
- 1990-02-27 US US07/602,221 patent/US5258301A/en not_active Expired - Lifetime
- 1990-02-27 AU AU51080/90A patent/AU631607B2/en not_active Ceased
-
1993
- 1993-05-04 US US08/056,745 patent/US5384251A/en not_active Expired - Lifetime
-
1994
- 1994-10-07 US US08/319,574 patent/US5506122A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69027154D1 (de) | 1996-07-04 |
| AU5108090A (en) | 1990-09-26 |
| KR920700290A (ko) | 1992-02-19 |
| CA2028119C (fr) | 2000-05-16 |
| US5258301A (en) | 1993-11-02 |
| WO1990010080A1 (fr) | 1990-09-07 |
| EP0411158B1 (fr) | 1996-05-29 |
| US5384251A (en) | 1995-01-24 |
| ES2089010T3 (es) | 1996-10-01 |
| EP0411158A1 (fr) | 1991-02-06 |
| CA2028119A1 (fr) | 1990-08-29 |
| AU631607B2 (en) | 1992-12-03 |
| US5506122A (en) | 1996-04-09 |
| EP0411158A4 (en) | 1992-03-11 |
| ATE138689T1 (de) | 1996-06-15 |
| JP2795748B2 (ja) | 1998-09-10 |
| DE69027154T2 (de) | 1996-10-24 |
| KR970010134B1 (ko) | 1997-06-21 |
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