DK0468875T3 - Self-adhesive matrix system for extended release of piribedil by transcutaneous pathway - Google Patents
Self-adhesive matrix system for extended release of piribedil by transcutaneous pathwayInfo
- Publication number
- DK0468875T3 DK0468875T3 DK91402036.7T DK91402036T DK0468875T3 DK 0468875 T3 DK0468875 T3 DK 0468875T3 DK 91402036 T DK91402036 T DK 91402036T DK 0468875 T3 DK0468875 T3 DK 0468875T3
- Authority
- DK
- Denmark
- Prior art keywords
- piribedil
- self
- matrix system
- extended release
- adhesive matrix
- Prior art date
Links
- OQDPVLVUJFGPGQ-UHFFFAOYSA-N 2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]pyrimidine Chemical compound C=1C=C2OCOC2=CC=1CN(CC1)CCN1C1=NC=CC=N1 OQDPVLVUJFGPGQ-UHFFFAOYSA-N 0.000 title abstract 3
- 229960004310 piribedil Drugs 0.000 title abstract 3
- 239000000853 adhesive Substances 0.000 title abstract 2
- 239000011159 matrix material Substances 0.000 title abstract 2
- 238000013265 extended release Methods 0.000 title 1
- 230000037361 pathway Effects 0.000 title 1
- 238000009792 diffusion process Methods 0.000 abstract 1
- 229920002379 silicone rubber Polymers 0.000 abstract 1
- 238000013268 sustained release Methods 0.000 abstract 1
- 239000012730 sustained-release form Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
Abstract
The invention relates to a self-adhesive silicone elastomer matrix system for the sustained release of piribedil, which provides for the continuous and steady transdermal diffusion of piribedil.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9009361A FR2664815B1 (en) | 1990-07-23 | 1990-07-23 | SELF-ADHESIVE MATRIX SYSTEM FOR THE EXTENDED RELEASE OF THE PIRIBEDIL BY TRANSCUTANEOUS ROUTE. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0468875T3 true DK0468875T3 (en) | 1995-11-20 |
Family
ID=9398984
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91402036.7T DK0468875T3 (en) | 1990-07-23 | 1991-07-23 | Self-adhesive matrix system for extended release of piribedil by transcutaneous pathway |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0468875B1 (en) |
| JP (1) | JPH04234322A (en) |
| AT (1) | ATE124271T1 (en) |
| AU (1) | AU635653B2 (en) |
| CA (1) | CA2047508A1 (en) |
| DE (1) | DE69110781T2 (en) |
| DK (1) | DK0468875T3 (en) |
| ES (1) | ES2075942T3 (en) |
| FR (1) | FR2664815B1 (en) |
| GR (1) | GR3017276T3 (en) |
| IE (1) | IE912577A1 (en) |
| NZ (1) | NZ239074A (en) |
| OA (1) | OA09384A (en) |
| PT (1) | PT98416B (en) |
| ZA (1) | ZA915769B (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2675383B1 (en) * | 1991-04-18 | 1995-05-12 | Bernard Aranda | USE OF A MEDICINAL PRODUCT FOR THE MANUFACTURE OF A MEDICINAL PRODUCT FOR THE TREATMENT OF HYPERACTIVE OR UNSTABLE BLADDER. |
| FR2691361B1 (en) | 1992-05-19 | 1994-07-08 | Adir | SELF-ADHESIVE MATRIX SYSTEM FOR THE EXTENDED RELEASE OF THE PIRIBEDIL BY TRANSCUTANEOUS ROUTE. |
| DE19512181C2 (en) * | 1995-03-31 | 2003-11-06 | Hexal Pharma Gmbh | Transdermal system with ramipril and / or trandolapril as an ACE inhibitor |
| US5785991A (en) * | 1995-06-07 | 1998-07-28 | Alza Corporation | Skin permeation enhancer compositions comprising glycerol monolaurate and lauryl acetate |
| ID30353A (en) * | 1999-02-05 | 2001-11-22 | Cipla Ltd | TOPICAL SPRAY MEDICINE |
| RU2358699C2 (en) | 2001-06-18 | 2009-06-20 | Ноувен Фамэсьютикэлз, Инк. | Percutaneous drug delivery composition (versions), method of production and application |
| US6805878B2 (en) | 2001-09-13 | 2004-10-19 | Noven Pharmaceuticals, Inc. | Transdermal administration of ACE inhibitors |
| CN105267173A (en) * | 2014-05-30 | 2016-01-27 | 北京星昊医药股份有限公司 | Piribedil sustained-release tablets and preparation method thereof |
| WO2016069898A1 (en) * | 2014-10-30 | 2016-05-06 | Textile-Based Delivery, Inc. | Delivery systems |
| CN105232475A (en) * | 2015-11-19 | 2016-01-13 | 哈尔滨圣吉药业股份有限公司 | A kind of piribedil sustained-release pellets and preparation method thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2519986A1 (en) * | 1982-01-21 | 1983-07-22 | Adir | NOVEL BENZODIOXINE DERIVATIVES, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME |
| DE3344691A1 (en) * | 1983-12-10 | 1985-06-20 | Bayer Ag, 5090 Leverkusen | ACTIVE GAS EXHAUST SYSTEMS |
| EP0196769B1 (en) * | 1985-02-25 | 1992-07-08 | Rutgers, The State University of New Jersey | A novel transdermal pharmaceutical absorption dosage unit |
| HU197519B (en) * | 1987-06-22 | 1989-04-28 | Biogal Gyogyszergyar | Process for producing medicine form capable for penetrating through epidermis and suitable for intaking the agent through epidermis by kinetics of zero-grade |
| FR2619388A1 (en) * | 1987-08-14 | 1989-02-17 | Rhone Poulenc Chimie | SOFT LAMINATE ARTICLE FOR TRANSFER ADHESIVE |
-
1990
- 1990-07-23 FR FR9009361A patent/FR2664815B1/en not_active Expired - Fee Related
-
1991
- 1991-07-22 PT PT98416A patent/PT98416B/en not_active IP Right Cessation
- 1991-07-22 AU AU81213/91A patent/AU635653B2/en not_active Ceased
- 1991-07-22 JP JP3180719A patent/JPH04234322A/en active Pending
- 1991-07-22 NZ NZ239074A patent/NZ239074A/en unknown
- 1991-07-22 CA CA002047508A patent/CA2047508A1/en not_active Abandoned
- 1991-07-23 OA OA60046A patent/OA09384A/en unknown
- 1991-07-23 EP EP91402036A patent/EP0468875B1/en not_active Expired - Lifetime
- 1991-07-23 IE IE257791A patent/IE912577A1/en unknown
- 1991-07-23 AT AT91402036T patent/ATE124271T1/en not_active IP Right Cessation
- 1991-07-23 DK DK91402036.7T patent/DK0468875T3/en active
- 1991-07-23 ES ES91402036T patent/ES2075942T3/en not_active Expired - Lifetime
- 1991-07-23 DE DE69110781T patent/DE69110781T2/en not_active Expired - Fee Related
- 1991-07-23 ZA ZA915769A patent/ZA915769B/en unknown
-
1995
- 1995-08-31 GR GR950402394T patent/GR3017276T3/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69110781T2 (en) | 1995-11-23 |
| ES2075942T3 (en) | 1995-10-16 |
| AU635653B2 (en) | 1993-03-25 |
| NZ239074A (en) | 1992-10-28 |
| EP0468875A3 (en) | 1992-04-01 |
| CA2047508A1 (en) | 1992-01-24 |
| IE912577A1 (en) | 1992-01-29 |
| FR2664815A1 (en) | 1992-01-24 |
| JPH04234322A (en) | 1992-08-24 |
| PT98416B (en) | 1999-01-29 |
| EP0468875B1 (en) | 1995-06-28 |
| PT98416A (en) | 1994-01-31 |
| FR2664815B1 (en) | 1994-11-04 |
| GR3017276T3 (en) | 1995-11-30 |
| ATE124271T1 (en) | 1995-07-15 |
| DE69110781D1 (en) | 1995-08-03 |
| AU8121391A (en) | 1992-01-30 |
| ZA915769B (en) | 1992-05-27 |
| EP0468875A2 (en) | 1992-01-29 |
| OA09384A (en) | 1992-09-15 |
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