DK0447116T3 - Urinstof-derivater, deres fremstilling samt lægemidler indeholdende sådanne derivater - Google Patents
Urinstof-derivater, deres fremstilling samt lægemidler indeholdende sådanne derivaterInfo
- Publication number
- DK0447116T3 DK0447116T3 DK91301868.5T DK91301868T DK0447116T3 DK 0447116 T3 DK0447116 T3 DK 0447116T3 DK 91301868 T DK91301868 T DK 91301868T DK 0447116 T3 DK0447116 T3 DK 0447116T3
- Authority
- DK
- Denmark
- Prior art keywords
- derivatives
- preparation
- urea derivatives
- drugs containing
- urea
- Prior art date
Links
- 150000003672 ureas Chemical class 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 102000001494 Sterol O-Acyltransferase Human genes 0.000 abstract 2
- 108010054082 Sterol O-acyltransferase Proteins 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/26—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/18—Systems containing only non-condensed rings with a ring being at least seven-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/18—Fluorenes; Hydrogenated fluorenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
- C07C2603/26—Phenanthrenes; Hydrogenated phenanthrenes
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6075490 | 1990-03-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0447116T3 true DK0447116T3 (da) | 1995-05-15 |
Family
ID=13151377
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91301868.5T DK0447116T3 (da) | 1990-03-12 | 1991-03-06 | Urinstof-derivater, deres fremstilling samt lægemidler indeholdende sådanne derivater |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0447116B1 (da) |
| JP (1) | JPH04234839A (da) |
| KR (1) | KR910016689A (da) |
| CN (1) | CN1024790C (da) |
| AT (1) | ATE115558T1 (da) |
| AU (1) | AU643759B2 (da) |
| CA (1) | CA2037669A1 (da) |
| DE (1) | DE69105786T2 (da) |
| DK (1) | DK0447116T3 (da) |
| ES (1) | ES2068497T3 (da) |
| FI (1) | FI911189L (da) |
| GR (1) | GR3015149T3 (da) |
| HU (1) | HUT57712A (da) |
| IE (1) | IE910780A1 (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU632809B2 (en) * | 1989-05-25 | 1993-01-14 | Takeda Chemical Industries Ltd. | Benzocycloalkane benzopyran and benzothiopyran urea derivatives and production thereof |
| RU94046149A (ru) * | 1992-05-28 | 1996-11-27 | Пфайзер Инк. (US) | Новые n-арил и n-гетероарил производные мочевины как ингибиторы ацил кофермента а:холестерин ацил трансферазы (асат) фармацевтическая композиция, способ ингибирования (асат) |
| US5401758A (en) * | 1993-10-07 | 1995-03-28 | Bristol-Myers Squibb Company | Pyridinyl cyanoguanidine compounds |
| DE4401893A1 (de) * | 1994-01-24 | 1995-07-27 | Bayer Ag | Substituierte Arylharnstoffe |
| EP0742208A1 (en) * | 1995-05-05 | 1996-11-13 | Grelan Pharmaceutical Co., Ltd. | 2-Ureido-benzamide derivatives |
| WO1997012860A1 (en) | 1995-10-05 | 1997-04-10 | Kyoto Pharmaceutical Industries, Ltd. | Novel heterocyclic derivatives and medicinal use thereof |
| US5866609A (en) * | 1996-08-09 | 1999-02-02 | Ss Pharmaceutical Co., Ltd. | Substituted vinylurea derivatives and medicine containing the same |
| JP2005507876A (ja) | 2001-09-05 | 2005-03-24 | ミナーバ バイオテクノロジーズ コーポレイション | 癌を治療する組成物および方法 |
| FR2831166B1 (fr) * | 2001-10-18 | 2004-02-27 | Sanofi Synthelabo | Aralkyl-tetrahydro-pyridines, leur preparation et compositions pharmaceutiques les contenant |
| DE60332851D1 (de) | 2002-07-17 | 2010-07-15 | Kyoto Pharma Ind | Indolinverbindung und deren medizinische verwendung |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2928485A1 (de) * | 1979-07-14 | 1981-01-29 | Bayer Ag | Verwendung von harnstoffderivaten als arzneimittel bei der behandlung von fettstoffwechselstoerungen |
| US4473579A (en) * | 1982-01-26 | 1984-09-25 | American Cyanamid Company | Antiatherosclerotic tetrasubstituted ureas and thioureas |
| JPS58222063A (ja) * | 1982-06-17 | 1983-12-23 | Nippon Tokushu Noyaku Seizo Kk | ベンジルウレア誘導体、その製法及び農園芸用殺菌剤 |
| US4868210A (en) * | 1988-03-30 | 1989-09-19 | Warner-Lambert Company | Antihyperlipidemic and antiatherosclerotic compounds and compositions |
| AU632809B2 (en) * | 1989-05-25 | 1993-01-14 | Takeda Chemical Industries Ltd. | Benzocycloalkane benzopyran and benzothiopyran urea derivatives and production thereof |
-
1991
- 1991-03-06 CA CA002037669A patent/CA2037669A1/en not_active Abandoned
- 1991-03-06 DE DE69105786T patent/DE69105786T2/de not_active Expired - Fee Related
- 1991-03-06 EP EP91301868A patent/EP0447116B1/en not_active Expired - Lifetime
- 1991-03-06 ES ES91301868T patent/ES2068497T3/es not_active Expired - Lifetime
- 1991-03-06 AT AT91301868T patent/ATE115558T1/de not_active IP Right Cessation
- 1991-03-06 DK DK91301868.5T patent/DK0447116T3/da active
- 1991-03-08 IE IE078091A patent/IE910780A1/en unknown
- 1991-03-08 AU AU72762/91A patent/AU643759B2/en not_active Ceased
- 1991-03-11 HU HU91784A patent/HUT57712A/hu unknown
- 1991-03-11 KR KR1019910003822A patent/KR910016689A/ko not_active Withdrawn
- 1991-03-11 FI FI911189A patent/FI911189L/fi not_active Application Discontinuation
- 1991-03-11 JP JP3125667A patent/JPH04234839A/ja active Pending
- 1991-03-12 CN CN91101592A patent/CN1024790C/zh not_active Expired - Fee Related
-
1995
- 1995-02-22 GR GR950400369T patent/GR3015149T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IE910780A1 (en) | 1991-09-25 |
| JPH04234839A (ja) | 1992-08-24 |
| DE69105786D1 (de) | 1995-01-26 |
| CN1024790C (zh) | 1994-06-01 |
| ES2068497T3 (es) | 1995-04-16 |
| ATE115558T1 (de) | 1994-12-15 |
| HUT57712A (en) | 1991-12-30 |
| GR3015149T3 (en) | 1995-05-31 |
| AU643759B2 (en) | 1993-11-25 |
| EP0447116B1 (en) | 1994-12-14 |
| FI911189A0 (fi) | 1991-03-11 |
| CA2037669A1 (en) | 1991-09-13 |
| KR910016689A (ko) | 1991-11-05 |
| DE69105786T2 (de) | 1995-04-27 |
| EP0447116A1 (en) | 1991-09-18 |
| FI911189A7 (fi) | 1991-09-13 |
| FI911189L (fi) | 1991-09-13 |
| CN1054766A (zh) | 1991-09-25 |
| HU910784D0 (en) | 1991-09-30 |
| AU7276291A (en) | 1991-09-12 |
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