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DE69232334D1 - Substituierte 3-aminochinuclidine - Google Patents

Substituierte 3-aminochinuclidine

Info

Publication number
DE69232334D1
DE69232334D1 DE69232334T DE69232334T DE69232334D1 DE 69232334 D1 DE69232334 D1 DE 69232334D1 DE 69232334 T DE69232334 T DE 69232334T DE 69232334 T DE69232334 T DE 69232334T DE 69232334 D1 DE69232334 D1 DE 69232334D1
Authority
DE
Germany
Prior art keywords
compounds
aminochinuclidine
substituted
disorders
antagonists
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69232334T
Other languages
English (en)
Other versions
DE69232334T2 (de
Inventor
Fumitaka Ito
Toshihide Kokura
Masami Nakane
Kunio Satake
Hiroaki Wakabayashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp Belgium
Pfizer Inc
Original Assignee
Pfizer Corp Belgium
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp Belgium, Pfizer Inc filed Critical Pfizer Corp Belgium
Application granted granted Critical
Publication of DE69232334D1 publication Critical patent/DE69232334D1/de
Publication of DE69232334T2 publication Critical patent/DE69232334T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicinal Preparation (AREA)
DE69232334T 1991-05-22 1992-05-19 Substituierte 3-aminochinuclidine Expired - Fee Related DE69232334T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP14682691 1991-05-22
PCT/US1992/004002 WO1992020676A1 (en) 1991-05-22 1992-05-19 Substituted 3-aminoquinuclidines

Publications (2)

Publication Number Publication Date
DE69232334D1 true DE69232334D1 (de) 2002-02-14
DE69232334T2 DE69232334T2 (de) 2002-11-14

Family

ID=15416402

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69232334T Expired - Fee Related DE69232334T2 (de) 1991-05-22 1992-05-19 Substituierte 3-aminochinuclidine
DE9290057U Expired - Lifetime DE9290057U1 (de) 1991-05-22 1992-05-19 Substituierte 3-Aminochinuclidine

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE9290057U Expired - Lifetime DE9290057U1 (de) 1991-05-22 1992-05-19 Substituierte 3-Aminochinuclidine

Country Status (25)

Country Link
EP (1) EP0585328B1 (de)
KR (1) KR100246065B1 (de)
CN (1) CN1041827C (de)
AT (1) ATE211743T1 (de)
AU (1) AU658898B2 (de)
BR (1) BR9206044A (de)
CA (1) CA2109415C (de)
CZ (1) CZ247993A3 (de)
DE (2) DE69232334T2 (de)
DK (1) DK0585328T3 (de)
EG (1) EG20218A (de)
ES (1) ES2168260T3 (de)
FI (1) FI935134A0 (de)
HU (1) HUT65771A (de)
IE (1) IE921662A1 (de)
IL (1) IL101960A (de)
MX (1) MX9202449A (de)
NO (1) NO305173B1 (de)
NZ (2) NZ242880A (de)
PL (4) PL172069B1 (de)
PT (1) PT100514B (de)
RU (1) RU2092486C1 (de)
UA (1) UA26401C2 (de)
WO (1) WO1992020676A1 (de)
ZA (1) ZA923773B (de)

Families Citing this family (72)

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BR9206161A (pt) * 1991-06-20 1995-10-31 Pfizer Derivados fluoroalcoxibenzilamino de heterociclos contendo nitrogénio
JP2656702B2 (ja) * 1992-03-23 1997-09-24 ファイザー製薬株式会社 ペプチド性キヌクリジン
EP1114823A3 (de) * 1992-08-19 2001-07-18 Pfizer Inc. Substituierte Benzylamin-Stickstoff enthaltende nichtaromatische Heterocyclen
JP2656699B2 (ja) * 1992-10-21 1997-09-24 ファイザー製薬株式会社 置換ベンジルアミノキヌクリジン
JP2656700B2 (ja) * 1992-10-28 1997-09-24 ファイザー製薬株式会社 置換キヌクリジン誘導体
US5837711A (en) * 1992-10-28 1998-11-17 Pfizer Inc. Substituted quinuclidines as substance P antagonists
CA2150123C (en) * 1992-12-10 2004-12-07 Harry R. Howard Aminomethylene substituted non-aromatic heterocycles
JP2822274B2 (ja) * 1993-05-19 1998-11-11 ファイザー製薬株式会社 Ｐ物質拮抗剤としてのヘテロ原子置換アルキルベンジルアミノキヌクリジン類
IL109646A0 (en) * 1993-05-19 1994-08-26 Pfizer Heteroatom substituted alkyl benzylamino-quinuclidines
US5393762A (en) * 1993-06-04 1995-02-28 Pfizer Inc. Pharmaceutical agents for treatment of emesis
WO1995002595A1 (en) * 1993-07-15 1995-01-26 Pfizer Inc. Benzyloxyquinuclidines as substance p antagonists
WO1995007886A1 (en) * 1993-09-17 1995-03-23 Pfizer Inc. 3-amino-5-carboxy-substituted piperidines and 3-amino-4-carboxy-substituted pyrrolidines as tachykinin antagonists
US6083943A (en) * 1993-09-17 2000-07-04 Pfizer Inc Substituted azaheterocyclecarboxylic acid
EP0653208A3 (de) * 1993-11-17 1995-10-11 Pfizer Substanz P Antagonisten zur Behandlung oder Verhütung des sonnenbrandes.
EP0659409A3 (de) * 1993-11-23 1995-08-09 Pfizer Substanz P Antagonisten zur Hemmung der Angiogenese.
EP0655246A1 (de) * 1993-11-30 1995-05-31 Pfizer Inc. Substanz P Antagonisten zur Behandlung von durch Helicobacter Pylori oder andere spirale Urease-positive Gram-negative Bakterien verursachten Krankheiten
FR2728169A1 (fr) 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des prurits et des dysesthesies oculaires ou palpebrales
FR2728166A1 (fr) 1994-12-19 1996-06-21 Oreal Composition topique contenant un antagoniste de substance p
FR2728165A1 (fr) 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des rougeurs cutanees d'origine neurogene
PE8798A1 (es) * 1995-07-17 1998-03-02 Pfizer Procedimiento de separacion de los enantiomeros del 1-azabiciclo[2.2.2] octan-3-amina, 2-(difenilmetil) -n- [[2-metoxi-5-(1-metiletil) fenil] metil]
TW458774B (en) 1995-10-20 2001-10-11 Pfizer Antiemetic pharmaceutical compositions
FR2741262B1 (fr) 1995-11-20 1999-03-05 Oreal Utilisation d'un antagoniste de tnf-alpha pour le traitement des rougeurs cutanees d'origine neurogene
MX9706944A (es) * 1996-09-12 1998-08-30 Pfizer Quinuclidinas sustituidas con tetrazolilo como antagonistas de la sustancia p.
NZ329807A (en) * 1997-04-23 2000-07-28 Pfizer NK-1 receptor antagonists and P receptor antagonists 2-Diarylmethyl-3-amino-1-azabicyclo[2.2.2]octane derivatives and amino substituted N-containing rings as agents for treating irritable bowel syndrome
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CN100430401C (zh) 2000-07-11 2008-11-05 Amr科技公司 新的4-苯基取代的四氢异喹啉类化合物及其治疗用途
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US6861526B2 (en) * 2002-10-16 2005-03-01 Pfizer Inc. Process for the preparation of (S,S)-cis-2-benzhydryl-3-benzylaminoquinuclidine
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MX2009007200A (es) 2007-01-10 2009-07-15 Angeletti P Ist Richerche Bio Indazoles sustituidos con amida como inhibidores de poli(adp-ribosa)polimerasa (parp).
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CN102638982B (zh) 2009-05-12 2015-07-08 百时美施贵宝公司 (S)-7-([1,2,4]三唑并[1,5-a]吡啶-6-基)-4-(3,4-二氯苯基)-1,2,3,4-四氢异喹啉的晶型及其用途
CN102458123A (zh) 2009-05-12 2012-05-16 阿尔巴尼分子研究公司 芳基、杂芳基和杂环取代的四氢异喹啉及其用途
JP5099731B1 (ja) 2009-10-14 2012-12-19 メルク・シャープ・アンド・ドーム・コーポレーション ｐ５３活性を増大する置換ピペリジン及びその使用
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Family Cites Families (1)

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Publication number Priority date Publication date Assignee Title
WO1990005525A1 (en) * 1988-11-23 1990-05-31 Pfizer Inc. Quinuclidine derivatives as substance p antagonists

Also Published As

Publication number Publication date
RU2092486C1 (ru) 1997-10-10
FI935134A7 (fi) 1993-11-19
NZ242880A (en) 1995-10-26
EP0585328A1 (de) 1994-03-09
PL171921B1 (pl) 1997-06-30
CZ247993A3 (en) 1994-07-13
PL170525B1 (en) 1996-12-31
UA26401C2 (uk) 1999-08-30
NO934195D0 (no) 1993-11-19
MX9202449A (es) 1993-03-01
NO934195L (no) 1993-11-19
AU1927592A (en) 1992-12-30
DK0585328T3 (da) 2002-02-11
ZA923773B (en) 1993-11-22
ES2168260T3 (es) 2002-06-16
PL172069B1 (pl) 1997-07-31
FI935134L (fi) 1993-11-19
DE9290057U1 (de) 1994-01-05
CA2109415A1 (en) 1992-11-23
DE69232334T2 (de) 2002-11-14
NO305173B1 (no) 1999-04-12
WO1992020676A1 (en) 1992-11-26
IL101960A0 (en) 1994-04-12
AU658898B2 (en) 1995-05-04
HU9303307D0 (en) 1994-03-28
EP0585328B1 (de) 2002-01-09
IL101960A (en) 1999-03-12
EG20218A (en) 1997-11-30
CA2109415C (en) 1998-12-29
CN1068571A (zh) 1993-02-03
ATE211743T1 (de) 2002-01-15
KR100246065B1 (en) 2000-04-01
PT100514A (pt) 1993-09-30
HUT65771A (en) 1994-07-28
PL170513B1 (en) 1996-12-31
FI935134A0 (fi) 1993-11-19
CN1041827C (zh) 1999-01-27
PT100514B (pt) 1999-06-30
NZ272941A (en) 1997-05-26
BR9206044A (pt) 1995-03-01
IE921662A1 (en) 1992-12-02

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