DE69939821D1 - Zusammensetzungen zur erhöhung der zahl antigen präsentierender zellen und der antitumoralen antwort in menschlichen patienten - Google Patents
Zusammensetzungen zur erhöhung der zahl antigen präsentierender zellen und der antitumoralen antwort in menschlichen patientenInfo
- Publication number
- DE69939821D1 DE69939821D1 DE69939821T DE69939821T DE69939821D1 DE 69939821 D1 DE69939821 D1 DE 69939821D1 DE 69939821 T DE69939821 T DE 69939821T DE 69939821 T DE69939821 T DE 69939821T DE 69939821 D1 DE69939821 D1 DE 69939821D1
- Authority
- DE
- Germany
- Prior art keywords
- csf
- present
- apc
- tumor
- administration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 230000000259 anti-tumor effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 102000004457 Granulocyte-Macrophage Colony-Stimulating Factor Human genes 0.000 abstract 5
- 108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 abstract 5
- 108090000978 Interleukin-4 Proteins 0.000 abstract 5
- 206010028980 Neoplasm Diseases 0.000 abstract 4
- 239000000427 antigen Substances 0.000 abstract 3
- 102000036639 antigens Human genes 0.000 abstract 3
- 108091007433 antigens Proteins 0.000 abstract 3
- 239000002243 precursor Substances 0.000 abstract 3
- 238000007910 systemic administration Methods 0.000 abstract 2
- 108090000695 Cytokines Proteins 0.000 abstract 1
- 102000004127 Cytokines Human genes 0.000 abstract 1
- 101000946889 Homo sapiens Monocyte differentiation antigen CD14 Proteins 0.000 abstract 1
- 102100035877 Monocyte differentiation antigen CD14 Human genes 0.000 abstract 1
- 210000001185 bone marrow Anatomy 0.000 abstract 1
- 238000011260 co-administration Methods 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 230000036039 immunity Effects 0.000 abstract 1
- 238000009169 immunotherapy Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000005259 peripheral blood Anatomy 0.000 abstract 1
- 239000011886 peripheral blood Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2026—IL-4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8051298P | 1998-04-02 | 1998-04-02 | |
| US11578899P | 1999-01-13 | 1999-01-13 | |
| PCT/US1999/007376 WO1999051257A1 (en) | 1998-04-02 | 1999-04-02 | Methods for enhancing antigen-presenting cells and anti-tumor responses in a human patient |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE69939821D1 true DE69939821D1 (de) | 2008-12-11 |
Family
ID=26763616
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69939821T Expired - Fee Related DE69939821D1 (de) | 1998-04-02 | 1999-04-02 | Zusammensetzungen zur erhöhung der zahl antigen präsentierender zellen und der antitumoralen antwort in menschlichen patienten |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1076564B1 (de) |
| JP (1) | JP2002510642A (de) |
| AT (1) | ATE412418T1 (de) |
| AU (1) | AU748850B2 (de) |
| CA (1) | CA2326739A1 (de) |
| DE (1) | DE69939821D1 (de) |
| WO (1) | WO1999051257A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1305041E (pt) * | 2000-07-28 | 2006-09-29 | Liponova Ag | Medicamento para a imunoterapia de tumores malignos |
| US20020094323A1 (en) | 2000-10-12 | 2002-07-18 | Kristoffer Hellstrand | Methods and compositions for promoting the maturation of monocytes |
| US7695723B2 (en) * | 2002-12-31 | 2010-04-13 | Sygnis Bioscience Gmbh & Co. Kg | Methods of treating neurological conditions with hematopoietic growth factors |
| WO2014066443A1 (en) * | 2012-10-23 | 2014-05-01 | Emory University | Gm-csf and il-4 conjugates, compositions, and methods related thereto |
| US10842743B2 (en) | 2016-04-08 | 2020-11-24 | The Regents Of The University Of California | Modified hyaluronic acid hydrogels and proteins for the time-controlled release of biologic agents |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6277368B1 (en) * | 1996-07-25 | 2001-08-21 | The Regents Of The University Of California | Cancer immunotherapy using autologous tumor cells combined with cells expressing a membrane cytokine |
| AU4818297A (en) * | 1996-10-16 | 1998-05-11 | Johns Hopkins University, The | Cytokine enhanced immunotherapy for brain tumors |
-
1999
- 1999-04-02 CA CA002326739A patent/CA2326739A1/en not_active Abandoned
- 1999-04-02 DE DE69939821T patent/DE69939821D1/de not_active Expired - Fee Related
- 1999-04-02 AU AU34695/99A patent/AU748850B2/en not_active Ceased
- 1999-04-02 WO PCT/US1999/007376 patent/WO1999051257A1/en not_active Ceased
- 1999-04-02 JP JP2000542028A patent/JP2002510642A/ja active Pending
- 1999-04-02 EP EP99916354A patent/EP1076564B1/de not_active Expired - Lifetime
- 1999-04-02 AT AT99916354T patent/ATE412418T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1076564A4 (de) | 2005-02-23 |
| CA2326739A1 (en) | 1999-10-14 |
| WO1999051257A1 (en) | 1999-10-14 |
| EP1076564A1 (de) | 2001-02-21 |
| AU3469599A (en) | 1999-10-25 |
| JP2002510642A (ja) | 2002-04-09 |
| AU748850B2 (en) | 2002-06-13 |
| EP1076564B1 (de) | 2008-10-29 |
| ATE412418T1 (de) | 2008-11-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2298418T3 (es) | Procedimiento para la preparacion de una libreria de arnm de antigenos tumorales. | |
| Wong | Oral complications and management strategies for patients undergoing cancer therapy | |
| Dilsiz et al. | Capillary hemangioma as a rare benign tumor of the oral cavity: a case report | |
| CA2727388C (en) | Telomerase-derived peptides for use in treatment of cancer | |
| JP2020023525A (ja) | ペプチド混合物 | |
| HUP0303125A2 (hu) | Bcl-2 rendellenességek kezelésére szolgáló eljárások bcl-2 antiszenz oligomerekkel | |
| IL169002A (en) | A preparation containing partially dendritic cells in vitro | |
| EA200601524A1 (ru) | Альфа-излучающие частицы гидроксиапатита | |
| IL153288A0 (en) | Use of growth hormone or a derivative thereof in the preparation of a medicament for hematopoiesis | |
| Huang et al. | Autologous transplantation of deciduous tooth pulp into necrotic young permanent teeth for pulp regeneration in a dog model | |
| WO2003039591A3 (de) | Allogene vakzine enthaltend eine ein costimulatorisches polypeptid exprimierende tumorzelle | |
| DE69939821D1 (de) | Zusammensetzungen zur erhöhung der zahl antigen präsentierender zellen und der antitumoralen antwort in menschlichen patienten | |
| Fioramonti et al. | A case of hydroxyurea-induced leg ulcer after definitive treatment suspension in a patient affected by thrombocythemia: effectiveness of a new collagenase | |
| WO2004104591A3 (en) | Improvements to gamma delta t cell-mediated therapy | |
| RU2335539C2 (ru) | Фармацевтический препарат и способ лечения злокачественных опухолей у человека с помощью аргининовой депривации | |
| MY141122A (en) | Vaccine composition containing transforming growth factor alpha (tgf[alpha]). it use in malignant diseases therapy | |
| Suntharalingam et al. | The use of concurrent chemotherapy with high-dose radiation before surgical resection in patients presenting with apical sulcus tumors. | |
| Le et al. | A case of dyskeratosis congenita with squamous cell carcinoma of the maxilla: a case report and review of the literature | |
| Brownson et al. | CXI Ewing's Sarcoma of the Maxilla | |
| TWI347194B (en) | Alpha-emitting hydroxyapatite particles | |
| Koranne et al. | Keratoameloblastoma-A Rare hybrid odontogenic tumor | |
| Casu et al. | Photodynamic Therapy in Non-Responsive Oral Angular Cheilitis: 4 Case Reports | |
| Hascoet et al. | Ameloblastic fibrosarcoma of the mandible: case report and literature review | |
| ES2791410T3 (es) | Uso de composiciones inmunomoduladoras eficaces para el tratamiento inmunoterápico de pacientes que padecen leucemias mielógenas | |
| Saleh et al. | The oral surgeon in the front-line of the diagnosis of Ewing sarcoma: a case report |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |