DE69936640D1 - Cannabinoiden als antioxidantien und neuroschützende mittel - Google Patents
Cannabinoiden als antioxidantien und neuroschützende mittelInfo
- Publication number
- DE69936640D1 DE69936640D1 DE69936640T DE69936640T DE69936640D1 DE 69936640 D1 DE69936640 D1 DE 69936640D1 DE 69936640 T DE69936640 T DE 69936640T DE 69936640 T DE69936640 T DE 69936640T DE 69936640 D1 DE69936640 D1 DE 69936640D1
- Authority
- DE
- Germany
- Prior art keywords
- cannabinoids
- useful
- found
- disease
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229930003827 cannabinoid Natural products 0.000 title abstract 7
- 239000003557 cannabinoid Substances 0.000 title abstract 7
- 229940065144 cannabinoids Drugs 0.000 title abstract 7
- 239000003963 antioxidant agent Substances 0.000 title abstract 2
- 239000003795 chemical substances by application Substances 0.000 title 1
- -1 age-related Diseases 0.000 abstract 2
- 230000000302 ischemic effect Effects 0.000 abstract 2
- 238000011282 treatment Methods 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 206010012289 Dementia Diseases 0.000 abstract 1
- 102000004868 N-Methyl-D-Aspartate Receptors Human genes 0.000 abstract 1
- 108090001041 N-Methyl-D-Aspartate Receptors Proteins 0.000 abstract 1
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- 230000008485 antagonism Effects 0.000 abstract 1
- 230000003078 antioxidant effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 208000014674 injury Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 230000000926 neurological effect Effects 0.000 abstract 1
- 239000004090 neuroprotective agent Substances 0.000 abstract 1
- 230000000324 neuroprotective effect Effects 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
- 230000008733 trauma Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Biochemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Toxicology (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrane Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8258998P | 1998-04-21 | 1998-04-21 | |
| US9599398P | 1998-08-10 | 1998-08-10 | |
| PCT/US1999/008769 WO1999053917A1 (en) | 1998-04-21 | 1999-04-21 | Cannabinoids as antioxidants and neuroprotectants |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE69936640D1 true DE69936640D1 (de) | 2007-09-06 |
Family
ID=26767641
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69936640T Expired - Lifetime DE69936640D1 (de) | 1998-04-21 | 1999-04-21 | Cannabinoiden als antioxidantien und neuroschützende mittel |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6630507B1 (de) |
| EP (1) | EP1071419B1 (de) |
| JP (1) | JP2002512188A (de) |
| AT (1) | ATE367809T1 (de) |
| AU (1) | AU766988B2 (de) |
| CA (1) | CA2329626A1 (de) |
| DE (1) | DE69936640D1 (de) |
| WO (1) | WO1999053917A1 (de) |
Families Citing this family (105)
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|---|---|---|---|---|
| AU766988B2 (en) * | 1998-04-21 | 2003-10-30 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Cannabinoids as antioxidants and neuroprotectants |
| JP2002539246A (ja) * | 1999-03-22 | 2002-11-19 | イミュジェン ファーマシューティカルズ インコーポレイティッド | 免疫疾患の治療 |
| US6566560B2 (en) * | 1999-03-22 | 2003-05-20 | Immugen Pharmaceuticals, Inc. | Resorcinolic compounds |
| US6563009B1 (en) | 1999-07-12 | 2003-05-13 | Virginia Commonwealth University | Vasodilator cannabinoid analogs |
| US8449908B2 (en) | 2000-12-22 | 2013-05-28 | Alltranz, Llc | Transdermal delivery of cannabidiol |
| CZ306277B6 (cs) * | 2001-02-14 | 2016-11-09 | Gw Pharma Limited | Pumpičkou aktivovaná kapalná sprejová formulace |
| BR0207325A (pt) | 2001-02-16 | 2004-02-10 | Daiichi Suntory Pharma Co Ltd | Métodos terapêuticos para doenças associadas com expressão diminuìda de gene de aop-1 ou aop-1 |
| GB2377218A (en) * | 2001-05-04 | 2003-01-08 | Gw Pharmaceuticals Ltd | Process and apparatus for extraction of active substances and enriched extracts from natural products |
| WO2003015700A2 (en) * | 2001-08-15 | 2003-02-27 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Novel vasoconstrictor cannabinoid analogs |
| US6825209B2 (en) | 2002-04-15 | 2004-11-30 | Research Triangle Institute | Compounds having unique CB1 receptor binding selectivity and methods for their production and use |
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| JP4569142B2 (ja) * | 2004-03-22 | 2010-10-27 | コニカミノルタホールディングス株式会社 | 表示素子 |
| EP1789054A2 (de) * | 2004-08-09 | 2007-05-30 | NovImmune SA | Cannabinoidzusammensetzungen und verfahren zu ihrer verwendung |
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| US9763894B2 (en) * | 2006-12-05 | 2017-09-19 | Virginia Commonwealth University | Inflammation therapy |
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| IL92238A (en) * | 1989-11-07 | 1995-07-31 | Yissum Res Dev Co | ADMN blocking product containing tetrahydrocannabinol history, several new tetrahydrocannabinol histories and process for their preparation |
| ATE157249T1 (de) | 1990-03-16 | 1997-09-15 | Us Health | Stickoxide zur gewichtsreduktion |
| DE4100441A1 (de) | 1991-01-09 | 1992-07-16 | Mack Chem Pharm | Verfahren zur herstellung von 6,12-dihydro-6-hydroxy-cannabidiol und dessen verwendung zur herstellung von trans-delta-9-tetrahydrocannabinol |
| US5635530A (en) | 1991-09-12 | 1997-06-03 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | (3S,4S)-delta-6-tetrahydrocannabinol-7-oic acids and derivatives thereof, processors for their preparation and pharmaceutical compositions containing them |
| IL99468A (en) | 1991-09-12 | 1997-09-30 | Yissum Res Dev Co | (3s, 4s)-delta- 6-tetrahydrocannabinol- 7-oic acids and derivatives thereof, processes for their preparation and pharmaceutical compositions containing them |
| US5538993A (en) * | 1991-09-12 | 1996-07-23 | Yissum Research Development Company | Certain tetrahydrocannabinol-7-oic acid derivatives |
| FR2713225B1 (fr) | 1993-12-02 | 1996-03-01 | Sanofi Sa | N-pipéridino-3-pyrazolecarboxamide substitué. |
| FR2692575B1 (fr) | 1992-06-23 | 1995-06-30 | Sanofi Elf | Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant. |
| WO1994012667A1 (en) | 1992-11-27 | 1994-06-09 | The United States Department Of The Army | Inhibitors of arachidonic acid metabolites for preventing neurological damage |
| US5696109A (en) | 1992-12-07 | 1997-12-09 | Eukarion, Inc. | Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease |
| CA2102142A1 (en) | 1993-03-30 | 1994-10-01 | Andrew J. Ghio | Method of inhibiting oxidants using alkylaryl polyether alcohol polymers |
| FR2714057B1 (fr) | 1993-12-17 | 1996-03-08 | Sanofi Elf | Nouveaux dérivés du 3-pyrazolecarboxamide, procédé pour leur préparation et compositions pharmaceutiques les contenant. |
| US5434295A (en) * | 1994-02-07 | 1995-07-18 | Yissum Research Development Company | Neuroprotective pharmaceutical compositions of 4-phenylpinene derivatives and certain novel 4-phenylpinene compounds |
| ZA958725B (en) | 1994-10-20 | 1997-04-16 | Lilly Co Eli | Treatment of disorders with duloxetine |
| IT1271267B (it) | 1994-12-14 | 1997-05-27 | Valle Francesco Della | Ammidi di acidi mono e bicarbossilici con amminoalcoli,selettivamente attive sul recettore periferico dei cannabinoidi |
| FR2741621B1 (fr) | 1995-11-23 | 1998-02-13 | Sanofi Sa | Nouveaux derives de pyrazole, procede pour leur preparation et compositions pharmaceutiques en contenant |
| GB9807639D0 (en) | 1998-04-14 | 1998-06-10 | Kennedy Rheumatology Inst | Anti-inflammatory agents |
| AU766988B2 (en) * | 1998-04-21 | 2003-10-30 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Cannabinoids as antioxidants and neuroprotectants |
-
1999
- 1999-04-21 AU AU38646/99A patent/AU766988B2/en not_active Expired
- 1999-04-21 AT AT99921427T patent/ATE367809T1/de not_active IP Right Cessation
- 1999-04-21 US US09/674,028 patent/US6630507B1/en not_active Expired - Lifetime
- 1999-04-21 DE DE69936640T patent/DE69936640D1/de not_active Expired - Lifetime
- 1999-04-21 WO PCT/US1999/008769 patent/WO1999053917A1/en not_active Ceased
- 1999-04-21 CA CA002329626A patent/CA2329626A1/en not_active Abandoned
- 1999-04-21 EP EP99921427A patent/EP1071419B1/de not_active Expired - Lifetime
- 1999-04-21 JP JP2000544322A patent/JP2002512188A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU3864699A (en) | 1999-11-08 |
| AU766988B2 (en) | 2003-10-30 |
| CA2329626A1 (en) | 1999-10-28 |
| EP1071419A1 (de) | 2001-01-31 |
| EP1071419B1 (de) | 2007-07-25 |
| WO1999053917A1 (en) | 1999-10-28 |
| ATE367809T1 (de) | 2007-08-15 |
| US6630507B1 (en) | 2003-10-07 |
| JP2002512188A (ja) | 2002-04-23 |
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