DE69932817D1 - Reinigungsverfahren zur herstellng von mannan bindendem lectin (mbl) und mbl enthaltende medizinische zubereitung - Google Patents
Reinigungsverfahren zur herstellng von mannan bindendem lectin (mbl) und mbl enthaltende medizinische zubereitungInfo
- Publication number
- DE69932817D1 DE69932817D1 DE69932817T DE69932817T DE69932817D1 DE 69932817 D1 DE69932817 D1 DE 69932817D1 DE 69932817 T DE69932817 T DE 69932817T DE 69932817 T DE69932817 T DE 69932817T DE 69932817 D1 DE69932817 D1 DE 69932817D1
- Authority
- DE
- Germany
- Prior art keywords
- mbl
- product
- virus
- manufacture
- cleaning procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 102000009112 Mannose-Binding Lectin Human genes 0.000 title 2
- 108010087870 Mannose-Binding Lectin Proteins 0.000 title 2
- 238000004140 cleaning Methods 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- 239000000047 product Substances 0.000 abstract 3
- 238000001042 affinity chromatography Methods 0.000 abstract 2
- 238000000746 purification Methods 0.000 abstract 2
- 239000007858 starting material Substances 0.000 abstract 2
- 210000003022 colostrum Anatomy 0.000 abstract 1
- 235000021277 colostrum Nutrition 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
- 235000013336 milk Nutrition 0.000 abstract 1
- 239000008267 milk Substances 0.000 abstract 1
- 210000004080 milk Anatomy 0.000 abstract 1
- 108010058237 plasma protein fraction Proteins 0.000 abstract 1
- 229940081857 plasma protein fraction Drugs 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
- 238000007781 pre-processing Methods 0.000 abstract 1
- 239000006228 supernatant Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4726—Lectins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK79398 | 1998-06-10 | ||
| DK79398 | 1998-06-10 | ||
| US10100798P | 1998-09-18 | 1998-09-18 | |
| US101007P | 1998-09-18 | ||
| PCT/DK1999/000319 WO1999064453A1 (en) | 1998-06-10 | 1999-06-10 | Purification process for production of mannan-binding lectin and an mbl medicinal product |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69932817D1 true DE69932817D1 (de) | 2006-09-28 |
| DE69932817T2 DE69932817T2 (de) | 2007-03-15 |
Family
ID=26064673
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69932817T Expired - Lifetime DE69932817T2 (de) | 1998-06-10 | 1999-06-10 | Reinigungsverfahren zur herstellng von mannan bindendem lectin (mbl) und mbl enthaltende medizinische zubereitung |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1084143B1 (de) |
| AT (1) | ATE336504T1 (de) |
| AU (1) | AU764066B2 (de) |
| CA (1) | CA2334696C (de) |
| DE (1) | DE69932817T2 (de) |
| DK (1) | DK1084143T3 (de) |
| ES (1) | ES2272067T3 (de) |
| NZ (1) | NZ509089A (de) |
| WO (1) | WO1999064453A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100497849B1 (ko) | 1997-08-21 | 2005-06-29 | 다카라 바이오 가부시키가이샤 | 제암제 |
| AU781135B2 (en) * | 1999-05-14 | 2005-05-05 | Thomas Vorup Jensen | Recombinant human mannan-binding lectin |
| US7387993B2 (en) * | 2000-07-13 | 2008-06-17 | Natimmune A/S | Mannan-binding lectin (MBL) treatment of infections in individuals treated with TNF-αinhibitors |
| EP1412377A1 (de) | 2001-07-23 | 2004-04-28 | Natimmune A/S | Herstellung von hochmolekularen lectinen |
| WO2003018617A1 (en) * | 2001-08-31 | 2003-03-06 | Fuso Pharmaceutical Industries, Ltd. | Method of purifying human mannose binding lectin, human mannose binding lectin compositions and medicinal use of human mannose binding lectin |
| ES2271515T3 (es) * | 2002-03-15 | 2007-04-16 | Natimmune A/S | Composiciones farmaceuticas que comprenden lecitina de union a manosa. |
| EP1501537A4 (de) * | 2002-04-24 | 2008-01-16 | Queensland Inst Med Res | Mannose bindendes lectin und seine verwendungszwecke |
| GB0222014D0 (en) * | 2002-09-23 | 2002-10-30 | Leuven K U Res & Dev | Mannan-binding lectin |
| WO2006035024A1 (en) * | 2004-09-29 | 2006-04-06 | Mellitus, S.L. | Method for detecting a predisposition to develop gestational diabetes mellitus and treatment for this disease |
| WO2006042541A1 (en) * | 2004-10-21 | 2006-04-27 | Statens Serum Institut | A method comprising nanofiltration to obtain an mbl product safe from infectious agents and the product obtainable by this method |
| WO2007095154A2 (en) * | 2006-02-10 | 2007-08-23 | The Brigham And Women's Hospital, Inc. | Lectin complement pathway assays and related compositions and methods |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5270199A (en) * | 1987-08-20 | 1993-12-14 | The Children's Medical Center Corporation | Human mannose-binding protein |
-
1999
- 1999-06-10 AT AT99924806T patent/ATE336504T1/de active
- 1999-06-10 DE DE69932817T patent/DE69932817T2/de not_active Expired - Lifetime
- 1999-06-10 DK DK99924806T patent/DK1084143T3/da active
- 1999-06-10 AU AU41343/99A patent/AU764066B2/en not_active Expired
- 1999-06-10 EP EP99924806A patent/EP1084143B1/de not_active Expired - Lifetime
- 1999-06-10 ES ES99924806T patent/ES2272067T3/es not_active Expired - Lifetime
- 1999-06-10 WO PCT/DK1999/000319 patent/WO1999064453A1/en not_active Ceased
- 1999-06-10 NZ NZ509089A patent/NZ509089A/xx not_active IP Right Cessation
- 1999-06-10 CA CA2334696A patent/CA2334696C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DK1084143T3 (da) | 2006-12-27 |
| AU4134399A (en) | 1999-12-30 |
| NZ509089A (en) | 2002-10-25 |
| CA2334696A1 (en) | 1999-12-16 |
| ATE336504T1 (de) | 2006-09-15 |
| CA2334696C (en) | 2014-03-25 |
| ES2272067T3 (es) | 2007-04-16 |
| DE69932817T2 (de) | 2007-03-15 |
| EP1084143B1 (de) | 2006-08-16 |
| AU764066B2 (en) | 2003-08-07 |
| EP1084143A1 (de) | 2001-03-21 |
| WO1999064453A1 (en) | 1999-12-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |