DE69919566D1 - Analyse von "amplikons" erhalten durch restriktionsendonukleasen - Google Patents

Analyse von "amplikons" erhalten durch restriktionsendonukleasen

Info

Publication number: DE69919566D1
Authority: DE; Germany
Prior art keywords: analysis; restriction endonuclease; polymorphisms; amplification; amplicons
Prior art date: 1998-11-09
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE69919566T

Other languages

English (en)

Inventor

Marc Zabeau

Patrick Stanssens

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Methexis Genomics NV

Original Assignee

Methexis Genomics NV

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-11-09

Filing date

1999-11-09

Publication date

2004-09-23

1999-11-09 Application filed by Methexis Genomics NV filed Critical Methexis Genomics NV

2004-09-23 Application granted granted Critical

2004-09-23 Publication of DE69919566D1 publication Critical patent/DE69919566D1/de

2019-11-10 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

108091008146 restriction endonucleases Proteins 0.000 title abstract 4
238000004458 analytical method Methods 0.000 title abstract 3
108091093088 Amplicon Proteins 0.000 title abstract 2
238000000034 method Methods 0.000 abstract 4
102000054765 polymorphisms of proteins Human genes 0.000 abstract 3
230000003321 amplification Effects 0.000 abstract 2
239000003153 chemical reaction reagent Substances 0.000 abstract 2
238000003776 cleavage reaction Methods 0.000 abstract 2
238000003199 nucleic acid amplification method Methods 0.000 abstract 2
230000007017 scission Effects 0.000 abstract 2
108700028369 Alleles Proteins 0.000 abstract 1
108010042407 Endonucleases Proteins 0.000 abstract 1
102000004533 Endonucleases Human genes 0.000 abstract 1
108091034117 Oligonucleotide Proteins 0.000 abstract 1
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 1
238000001514 detection method Methods 0.000 abstract 1
239000012634 fragment Substances 0.000 abstract 1
238000003205 genotyping method Methods 0.000 abstract 1
238000009396 hybridization Methods 0.000 abstract 1
230000035772 mutation Effects 0.000 abstract 1
239000002773 nucleotide Substances 0.000 abstract 1
125000003729 nucleotide group Chemical group 0.000 abstract 1
239000000523 sample Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
- C12Q1/683—Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
- C12Q1/6855—Ligating adaptors

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Wood Science & Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Analytical Chemistry (AREA)
Biotechnology (AREA)
Physics & Mathematics (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Chemical Kinetics & Catalysis (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Enzymes And Modification Thereof (AREA)
Steroid Compounds (AREA)
Analysing Materials By The Use Of Radiation (AREA)
Medicines Containing Plant Substances (AREA)

DE69919566T 1998-11-09 1999-11-09 Analyse von "amplikons" erhalten durch restriktionsendonukleasen Expired - Lifetime DE69919566D1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US10729398P	1998-11-09	1998-11-09
PCT/IB1999/001958 WO2000028081A2 (en)	1998-11-09	1999-11-09	Restricted amplicon analysis

Publications (1)

Publication Number	Publication Date
DE69919566D1 true DE69919566D1 (de)	2004-09-23

Family

ID=22315892

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69919566T Expired - Lifetime DE69919566D1 (de)	1998-11-09	1999-11-09	Analyse von "amplikons" erhalten durch restriktionsendonukleasen

Country Status (5)

Country	Link
EP (1)	EP1129219B1 (de)
AT (1)	ATE274069T1 (de)
AU (1)	AU1402900A (de)
DE (1)	DE69919566D1 (de)
WO (1)	WO2000028081A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1444364A4 (de) *	2001-10-27	2006-03-15	Sigma Genosys Inc	Multiple oligonukleotide pro gen für die anwendung bei gen-arrays
US20030124539A1 (en) *	2001-12-21	2003-07-03	Affymetrix, Inc. A Corporation Organized Under The Laws Of The State Of Delaware	High throughput resequencing and variation detection using high density microarrays
US7354715B2 (en)	2003-05-22	2008-04-08	Dow Agrosciences Llc	High-throughput methods of screening DNA for deletions and other mutations
ES2301342B1 (es) *	2006-03-14	2009-05-01	Oryzon Genomics, S.A.	"metodo de analisis de acidos nucleicos".
WO2008118988A1 (en)	2007-03-26	2008-10-02	Sequenom, Inc.	Restriction endonuclease enhanced polymorphic sequence detection
WO2009120808A2 (en)	2008-03-26	2009-10-01	Sequenom, Inc.	Restriction endonuclease enhanced polymorphic sequence detection

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1991017262A1 (en) *	1990-04-30	1991-11-14	The University Of British Columbia	Method of establishing identity
ATE382094T1 (de) *	1991-09-24	2008-01-15	Keygene Nv	Primer, sätze und restriktions fragmente und dessen benutzung in selektive restriktionsfragmentenamplifikation
US5512441A (en) *	1994-11-15	1996-04-30	American Health Foundation	Quantative method for early detection of mutant alleles and diagnostic kits for carrying out the method
WO1996017082A2 (en) *	1994-11-28	1996-06-06	E.I. Du Pont De Nemours And Company	Compound microsatellite primers for the detection of genetic polymorphisms
WO1997029211A1 (en) *	1996-02-09	1997-08-14	The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services	RESTRICTION DISPLAY (RD-PCR) OF DIFFERENTIALLY EXPRESSED mRNAs
WO1997034015A1 (en) *	1996-03-15	1997-09-18	The Penn State Research Foundation	Detection of extracellular tumor-associated nucleic acid in blood plasma or serum using nucleic acid amplification assays
CA2266750A1 (en) *	1996-09-18	1998-03-26	The General Hospital Corporation	Cleaved amplified rflp detection methods

1999
- 1999-11-09 WO PCT/IB1999/001958 patent/WO2000028081A2/en not_active Ceased
- 1999-11-09 DE DE69919566T patent/DE69919566D1/de not_active Expired - Lifetime
- 1999-11-09 AU AU14029/00A patent/AU1402900A/en not_active Abandoned
- 1999-11-09 AT AT99971866T patent/ATE274069T1/de not_active IP Right Cessation
- 1999-11-09 EP EP99971866A patent/EP1129219B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
WO2000028081A3 (en)	2000-08-03
AU1402900A (en)	2000-05-29
WO2000028081A9 (en)	2000-10-19
ATE274069T1 (de)	2004-09-15
EP1129219B1 (de)	2004-08-18
WO2000028081A2 (en)	2000-05-18
EP1129219A2 (de)	2001-09-05

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Legal Events

Date	Code	Title	Description
2005-07-21	8332	No legal effect for de