DE69916829D1 - Genetisch veränderte fibroblasten und ihre verwendung - Google Patents
Genetisch veränderte fibroblasten und ihre verwendungInfo
- Publication number
- DE69916829D1 DE69916829D1 DE69916829T DE69916829T DE69916829D1 DE 69916829 D1 DE69916829 D1 DE 69916829D1 DE 69916829 T DE69916829 T DE 69916829T DE 69916829 T DE69916829 T DE 69916829T DE 69916829 D1 DE69916829 D1 DE 69916829D1
- Authority
- DE
- Germany
- Prior art keywords
- genetically modified
- modified fibroblasts
- fibroblasts
- genetically
- expression
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 210000002950 fibroblast Anatomy 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 230000009395 genetic defect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000003205 muscle Anatomy 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0658—Skeletal muscle cells, e.g. myocytes, myotubes, myoblasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
- C12N2506/1307—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from adult fibroblasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Rheumatology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT98MI001004A IT1299201B1 (it) | 1998-05-08 | 1998-05-08 | Fibroblasti modificati geneticamente e loro uso |
| PCT/EP1999/003075 WO1999058646A1 (en) | 1998-05-08 | 1999-05-05 | Genetically-modified fibroblasts and the use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE69916829D1 true DE69916829D1 (de) | 2004-06-03 |
Family
ID=11379982
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69916829T Expired - Fee Related DE69916829D1 (de) | 1998-05-08 | 1999-05-05 | Genetisch veränderte fibroblasten und ihre verwendung |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1084232B1 (de) |
| JP (1) | JP2002514409A (de) |
| AT (1) | ATE265526T1 (de) |
| AU (1) | AU4037299A (de) |
| CA (1) | CA2331826A1 (de) |
| DE (1) | DE69916829D1 (de) |
| IT (1) | IT1299201B1 (de) |
| WO (1) | WO1999058646A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6783980B2 (en) | 1995-06-15 | 2004-08-31 | Crucell Holland B.V. | Packaging systems for human recombinant adenovirus to be used in gene therapy |
| US6913922B1 (en) | 1999-05-18 | 2005-07-05 | Crucell Holland B.V. | Serotype of adenovirus and uses thereof |
| US6492169B1 (en) | 1999-05-18 | 2002-12-10 | Crucell Holland, B.V. | Complementing cell lines |
| EP1157999A1 (de) * | 2000-05-24 | 2001-11-28 | Introgene B.V. | Verfahren und Mitteln zur Verbesserung der Haut-Transplantation mittels Genabgabe-Vehikel mit Tropismus für primären Fibroblasten, sowie andere Verwendungsmöglichkeiten für diesen |
| US7235233B2 (en) | 2000-09-26 | 2007-06-26 | Crucell Holland B.V. | Serotype 5 adenoviral vectors with chimeric fibers for gene delivery in skeletal muscle cells or myoblasts |
| ATE447037T1 (de) | 2002-04-25 | 2009-11-15 | Crucell Holland Bv | Mittel und verfahren zur herstellung von adenovirusvektoren |
| JP2010148440A (ja) * | 2008-12-25 | 2010-07-08 | Japan Health Science Foundation | 組換えアデノウイルス迅速構築システム |
| US20200338134A1 (en) * | 2019-04-26 | 2020-10-29 | Cleveland State University | Muscle treatment method using myod mutant |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5219740A (en) * | 1987-02-13 | 1993-06-15 | Fred Hutchinson Cancer Research Center | Retroviral gene transfer into diploid fibroblasts for gene therapy |
| AU1052795A (en) * | 1993-11-08 | 1995-05-29 | University Of Southern California | Compositions and methods for transduction of cells |
| GB9419048D0 (en) * | 1994-09-20 | 1994-11-09 | Watt Diana J | Treatment of muscular disorders |
| CA2269096C (en) * | 1996-10-18 | 2009-12-15 | Universite Laval | Method for in vitro preconditioning of myoblasts before transplantation |
-
1998
- 1998-05-08 IT IT98MI001004A patent/IT1299201B1/it active IP Right Grant
-
1999
- 1999-05-05 CA CA002331826A patent/CA2331826A1/en not_active Abandoned
- 1999-05-05 JP JP2000548438A patent/JP2002514409A/ja active Pending
- 1999-05-05 DE DE69916829T patent/DE69916829D1/de not_active Expired - Fee Related
- 1999-05-05 EP EP99923531A patent/EP1084232B1/de not_active Expired - Lifetime
- 1999-05-05 AU AU40372/99A patent/AU4037299A/en not_active Abandoned
- 1999-05-05 AT AT99923531T patent/ATE265526T1/de not_active IP Right Cessation
- 1999-05-05 WO PCT/EP1999/003075 patent/WO1999058646A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1084232B1 (de) | 2004-04-28 |
| JP2002514409A (ja) | 2002-05-21 |
| ATE265526T1 (de) | 2004-05-15 |
| IT1299201B1 (it) | 2000-02-29 |
| WO1999058646A1 (en) | 1999-11-18 |
| AU4037299A (en) | 1999-11-29 |
| CA2331826A1 (en) | 1999-11-18 |
| EP1084232A1 (de) | 2001-03-21 |
| ITMI981004A1 (it) | 1999-11-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8339 | Ceased/non-payment of the annual fee |