[go: up one dir, main page]

DE69907664D1 - Verfahren zur Herstellung von wässrigen Formulierungen für ophthalmische Verwendung - Google Patents

Verfahren zur Herstellung von wässrigen Formulierungen für ophthalmische Verwendung

Info

Publication number
DE69907664D1
DE69907664D1 DE69907664T DE69907664T DE69907664D1 DE 69907664 D1 DE69907664 D1 DE 69907664D1 DE 69907664 T DE69907664 T DE 69907664T DE 69907664 T DE69907664 T DE 69907664T DE 69907664 D1 DE69907664 D1 DE 69907664D1
Authority
DE
Germany
Prior art keywords
preparation
aqueous formulations
ophthalmic use
ophthalmic
formulations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69907664T
Other languages
English (en)
Other versions
DE69907664T2 (de
Inventor
Antonino Asero
Maria Grazia Mazzone
Valeria Moschetti
Anna Rita Blanco
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
S I F I IND FARMACEUTI Soc
Original Assignee
S I F I IND FARMACEUTI Soc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by S I F I IND FARMACEUTI Soc filed Critical S I F I IND FARMACEUTI Soc
Application granted granted Critical
Publication of DE69907664D1 publication Critical patent/DE69907664D1/de
Publication of DE69907664T2 publication Critical patent/DE69907664T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69907664T 1999-08-09 1999-12-22 Verfahren zur Herstellung von wässrigen Formulierungen für ophthalmische Verwendung Expired - Fee Related DE69907664T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1999MI001803A IT1313610B1 (it) 1999-08-09 1999-08-09 Processo per la preparazione di formulazioni acquose per uso oftalmico
ITMI991803 1999-08-09

Publications (2)

Publication Number Publication Date
DE69907664D1 true DE69907664D1 (de) 2003-06-12
DE69907664T2 DE69907664T2 (de) 2004-04-08

Family

ID=11383545

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69907664T Expired - Fee Related DE69907664T2 (de) 1999-08-09 1999-12-22 Verfahren zur Herstellung von wässrigen Formulierungen für ophthalmische Verwendung

Country Status (11)

Country Link
US (1) US6277829B1 (de)
EP (1) EP1075837B1 (de)
JP (1) JP2001089378A (de)
AT (1) ATE239448T1 (de)
CA (1) CA2315594A1 (de)
DE (1) DE69907664T2 (de)
DK (1) DK1075837T3 (de)
ES (1) ES2193658T3 (de)
IT (1) IT1313610B1 (de)
MX (1) MXPA00007530A (de)
PT (1) PT1075837E (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6239113B1 (en) 1999-03-31 2001-05-29 Insite Vision, Incorporated Topical treatment or prevention of ocular infections
US7056893B2 (en) 1999-03-31 2006-06-06 Insite Vision, Inc. Topical treatment for prevention of ocular infections
WO2002007736A1 (en) * 2000-07-24 2002-01-31 Cadila Pharmaceuticals Limited The process for manufacturing of clear liquid pharmaceutical composition of azithromycin
HRP20010301A2 (en) * 2001-04-27 2001-12-31 Pliva D D New therapeutic indication for azithromycin in the treatment of non-infective inflammatory diseases
EP1284143A1 (de) * 2001-08-17 2003-02-19 Sifi S.p.A Verfahren zur Herstellung von pharmazeutischen Lactoferrin enthaltenden Formulierungen
IL161398A0 (en) * 2001-10-18 2004-09-27 Teva Pharma Stabilized azithromycin compositions
US20090215735A1 (en) * 2002-02-25 2009-08-27 Alcon, Inc. Topical solution formulations containing a corticosteroid and a cyclodextrin
US20040023935A1 (en) * 2002-08-02 2004-02-05 Dey, L.P. Inhalation compositions, methods of use thereof, and process for preparation of same
US20040109826A1 (en) * 2002-12-06 2004-06-10 Dey, L.P. Stabilized albuterol compositions and method of preparation thereof
KR20120035220A (ko) * 2003-01-22 2012-04-13 센주 세이야꾸 가부시키가이샤 안질환 치료용 경피 흡수형 제제, 그 사용, 및 안질환 치료약의 눈의 국소 조직으로의 이행 방법
ES2220229B1 (es) * 2003-05-29 2005-10-16 Quimica Sintetica, S.A. Sales de adicion de azitromicina y acido citrico y procedimiento para su obtencion.
US20050013835A1 (en) * 2003-07-15 2005-01-20 Pfizer Inc. Stable non-dihydrate azithromycin oral suspensions
ATE529117T1 (de) * 2004-07-02 2011-11-15 Wakamoto Pharma Co Ltd Medizinische zusammensetzung auf wasserbasis mit azithromycin und herstellungsverfahren dafür
JP2007277095A (ja) * 2004-07-02 2007-10-25 Wakamoto Pharmaceut Co Ltd アジスロマイシン含有可逆性熱ゲル化水性組成物
US20060046970A1 (en) * 2004-08-31 2006-03-02 Insite Vision Incorporated Topical otic compositions and methods of topical treatment of prevention of otic infections
WO2010102078A1 (en) * 2009-03-04 2010-09-10 Allergan, Inc. Enhanced bimatoprost ophthalmic solution
US7851504B2 (en) 2005-03-16 2010-12-14 Allergan, Inc. Enhanced bimatoprost ophthalmic solution
WO2006121964A2 (en) * 2005-05-10 2006-11-16 Alcon, Inc. Ophthalmic suspension comprising an ophthalmic drug, a poloxamine and a glycol tonicity-adjusting agent, use of said composition for the manufacture of a medicament for treating ophthalmic disorders
JPWO2007074904A1 (ja) * 2005-12-28 2009-06-04 わかもと製薬株式会社 水性医薬組成物
FR2900575B1 (fr) * 2006-05-05 2008-10-17 Anteis Sa Gel biocompatible a liberation controlee, son procede de preparation et son utilisation
WO2008085913A1 (en) * 2007-01-04 2008-07-17 Rib-X Pharmaceuticals, Inc. Methods for treating, preventing, or reducing the risk of opthalmic, otic, and nasal infections
CN101668511A (zh) * 2007-02-28 2010-03-10 阿西克斯医疗公司 正常化睑板腺分泌的方法和化合物
US7795231B2 (en) * 2007-10-04 2010-09-14 Insite Vision Incorporated Concentrated aqueous azalide formulations
EP2098219A1 (de) 2008-03-05 2009-09-09 PARI Pharma GmbH Makrolidzusammensetzungen mit verbessertem Geschmack und verbesserter Stabilität
US20110059925A1 (en) * 2008-03-26 2011-03-10 Eric Donnenfeld Methods for improving lid margin and tear film function and treatment of lid margin disease using tetracycline family antibiotics
US8349806B2 (en) * 2008-07-10 2013-01-08 Inspire Pharmaceuticals, Inc. Method of treating blepharitis
US20100190734A1 (en) * 2009-01-23 2010-07-29 Romulus Kimbro Brazzell Method of treating dry eye disease with azithromycin
US9522153B2 (en) 2009-12-22 2016-12-20 Allergan, Inc. Compositions and methods for lowering intraocular pressure
CN103211755A (zh) * 2012-01-19 2013-07-24 武汉诺安药业有限公司 无菌稳定的阿奇霉素滴眼液的生产方法
US20180042953A1 (en) * 2012-06-08 2018-02-15 Obshchestvo S Ogranichennoy Otvetstvennostyu "Vik - Zdorovye Zhivotnykh" Antibacterial injectable pharmaceutical composition
RU2512683C2 (ru) * 2012-06-08 2014-04-10 Общество с ограниченной ответственностью "ВИК-здоровье животных" Антибактериальная инъекционная фармацевтическая композиция
CN103860515A (zh) * 2012-12-10 2014-06-18 中国科学院上海药物研究所 阿奇霉素渗透泵控释片及其制备方法
US9044508B2 (en) 2013-03-15 2015-06-02 Insite Vision Corporation Concentrated aqueous azalide formulations
HUE044329T2 (hu) * 2014-01-22 2019-10-28 Visufarma B V Iota-karragént tartalmazó készítmény vírusos kötõhártya-gyulladás ellen
RU2580630C1 (ru) * 2015-03-19 2016-04-10 Общество с ограниченной ответственностью "Научно-внедренческий центр Агроветзащита" Антибактериальное лекарственное средство в форме капель для лечения глазных болезней у животных
RU2580631C1 (ru) * 2015-03-19 2016-04-10 Общество с ограниченной ответственностью "Научно-внедренческий центр Агроветзащита" Антибактериальное лекарственное средство в форме мази для лечения глазных болезней у животных
EP4241759A1 (de) * 2016-10-12 2023-09-13 PS Therapy, Inc. Künstliche träne, kontaktlinse und arzneimittelträgerzusammensetzungen und verfahren zur verwendung davon
CN114796116A (zh) * 2022-05-17 2022-07-29 中山大学附属第六医院 一种阿奇霉素吸入剂及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989002271A1 (en) * 1987-09-10 1989-03-23 Pfizer Azithromycin and derivatives as antiprotozoal agents
CN1123279A (zh) * 1995-06-15 1996-05-29 沈家祥 阿奇霉素水溶性盐、其注射剂型以及它们的用途
US5705190A (en) * 1995-12-19 1998-01-06 Abbott Laboratories Controlled release formulation for poorly soluble basic drugs
US5646151A (en) * 1996-03-08 1997-07-08 Adolor Corporation Kappa agonist compounds and pharmaceutical formulations thereof
EP0925789B2 (de) * 1997-12-02 2009-06-17 Pfizer Products Inc. Verwendung von azithromycin zur topischen behandlung von augeninfektionen

Also Published As

Publication number Publication date
DE69907664T2 (de) 2004-04-08
ITMI991803A0 (it) 1999-08-09
ES2193658T3 (es) 2003-11-01
JP2001089378A (ja) 2001-04-03
CA2315594A1 (en) 2001-02-09
ATE239448T1 (de) 2003-05-15
PT1075837E (pt) 2003-08-29
EP1075837A3 (de) 2001-05-16
EP1075837B1 (de) 2003-05-07
ITMI991803A1 (it) 2001-02-09
IT1313610B1 (it) 2002-09-09
US6277829B1 (en) 2001-08-21
EP1075837A2 (de) 2001-02-14
DK1075837T3 (da) 2003-09-01
MXPA00007530A (es) 2002-06-04

Similar Documents

Publication Publication Date Title
DE69907664D1 (de) Verfahren zur Herstellung von wässrigen Formulierungen für ophthalmische Verwendung
NO2022001I1 (no) Pazopanib
CY1108514T1 (el) Παραγωγα 1-φαινυλαλκανεκαρβοξυλικου οξεος για τη θεραπεια νευρογενων ασθενειων
ATE271390T1 (de) Verwendung von azithromycin zur topischen behandlung von augeninfektionen
DK1301201T3 (da) Behandling af glycogenosis type II
NO20055130D0 (no) Aminocykloheksyleter-forbindelser og deres anvendelse
DE602004025267D1 (de) Verfahren zur herstellung form i von (s)-(+)- clopidogrelbisulfat
WO2003072541A3 (en) Chemical compounds
DE60239842D1 (de) Verfahren zur Herstellung von 10,11-dihydro-10-oxo-5h-dibenzoÄb,fÜazepin-5-carboxamid
FR2882751B1 (fr) Hydrazinocarbonyl-thieno[2,3-c]pyrazoles, procede de preparation, compositions les contenant et utilisation
DE502004009152D1 (de) Verfahren zur herstellung von derivaten des 4a,5,9,10,11,12-hexahydrobenzofuro ä3a,3,2üä 2 ü- benzazepins
DE60222806D1 (de) Verfahren zur herstellung von (1,4,5)-oxadiazepinderivaten
EP1338596A4 (de) Verfahren zur herstellung antibakterieller verbindungen vom carbapenem-typ
ATE437855T1 (de) (4,5,6,7-tetrahydro-1h-indol-7- yl)essigsäurederivate zur behandlung von alzheimer-krankheit
BR9915803A (pt) Composição para o tratamento de neuropatia da retina ou cabeça de nervo ótico, e, processo para tratamento de neuropatia da retina ou cabeça de nervo ótico
ATE310734T1 (de) Verfahren zur herstellung von n-substituierten 2, 6-dialkylmorpholinen
DE69926223D1 (de) Verfahren zur herstellung von zwischenprodukten
DE60335980D1 (de) Verfahren zur herstellung von synthetischen derivaten von dibenzylbutyrolacton-lignanen mit antichagas eigenschaften
EP1436279B8 (de) Chemische verbindungen
DE60031315D1 (de) Verfahren zur Herstellung von Derivaten von i(1,5-Diaryl)pyrazol-3-ylöpropansäure
DE60230097D1 (de) Verfahren zur herstellung von 1,5-diaminonaphthalinen
ATE241640T1 (de) Fusidinsäure-derivate
DE60143350D1 (de) Verfahren zur herstellung von 1,3-dialkyl-2-imidazolidinon-derivaten
DE60327567D1 (de) Verfahren zur herstellung von 3,3',4,4'-tetraaminobiphenyl
DE60038371D1 (de) Verfahren zur herstellung von s,s-2-hydroxypropylendiamin-n,n'-di-bernsteinsäure

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee