[go: up one dir, main page]

DE69901177D1 - Platinkomplex, dessen herstellung und dessen therapeutische verwendung - Google Patents

Platinkomplex, dessen herstellung und dessen therapeutische verwendung

Info

Publication number
DE69901177D1
DE69901177D1 DE69901177T DE69901177T DE69901177D1 DE 69901177 D1 DE69901177 D1 DE 69901177D1 DE 69901177 T DE69901177 T DE 69901177T DE 69901177 T DE69901177 T DE 69901177T DE 69901177 D1 DE69901177 D1 DE 69901177D1
Authority
DE
Germany
Prior art keywords
production
therapeutic use
platinum complex
platinum
complex
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69901177T
Other languages
English (en)
Other versions
DE69901177T2 (de
Inventor
Frantisek Zak
Adolf Mistr
Anna Poulova
Milan Melka
Jaroslav Turanek
Dana Zaluska
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pliva Lachema AS
Original Assignee
Pliva Lachema AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva Lachema AS filed Critical Pliva Lachema AS
Application granted granted Critical
Publication of DE69901177D1 publication Critical patent/DE69901177D1/de
Publication of DE69901177T2 publication Critical patent/DE69901177T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
DE69901177T 1998-05-27 1999-05-24 Platinkomplex, dessen herstellung und dessen therapeutische verwendung Expired - Lifetime DE69901177T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CZ19981628A CZ288912B6 (cs) 1998-05-27 1998-05-27 Komplex platiny v oxidačním čísle IV, způsob přípravy tohoto komplexu, tento komplex jako léčivo a farmaceutická kompozice tento komplex obsahující
PCT/CZ1999/000015 WO1999061451A1 (en) 1998-05-27 1999-05-24 Platinum complex, its preparation and therapeutic application

Publications (2)

Publication Number Publication Date
DE69901177D1 true DE69901177D1 (de) 2002-05-08
DE69901177T2 DE69901177T2 (de) 2002-10-02

Family

ID=5463562

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69901177T Expired - Lifetime DE69901177T2 (de) 1998-05-27 1999-05-24 Platinkomplex, dessen herstellung und dessen therapeutische verwendung

Country Status (24)

Country Link
US (1) US6503943B1 (de)
EP (1) EP1082330B1 (de)
JP (1) JP3575686B2 (de)
CN (1) CN1124279C (de)
AU (1) AU741380B2 (de)
BG (1) BG64599B1 (de)
BR (1) BR9910669B1 (de)
CA (1) CA2332054C (de)
CZ (1) CZ288912B6 (de)
DE (1) DE69901177T2 (de)
ES (1) ES2175968T3 (de)
HR (1) HRP20000791B1 (de)
HU (1) HU224716B1 (de)
IL (1) IL139529A (de)
MX (1) MXPA00011621A (de)
NO (1) NO328930B1 (de)
PL (1) PL191132B1 (de)
PT (1) PT1082330E (de)
RS (1) RS49738B (de)
RU (1) RU2200164C2 (de)
SI (1) SI1082330T1 (de)
SK (1) SK284436B6 (de)
UA (1) UA56315C2 (de)
WO (1) WO1999061451A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ295584B6 (cs) * 2004-02-12 2005-08-17 Pliva-Lachema A. S. Farmaceutická kompozice obsahující jako účinnou látku platinový komplex a způsob výroby této kompozice
CZ296045B6 (cs) * 2003-03-31 2005-12-14 Pliva-Lachema A. S. Farmaceutická kompozice obsahující jako účinnou látku komplex čtyřmocné platiny a způsob její výroby
EP1608358A1 (de) * 2003-03-31 2005-12-28 Pliva-Lachema A.S. Pharmazeutische zusammensetzung mit platinkomplexen
EP2027853A3 (de) 2004-06-18 2011-01-05 Agennix USA Inc. Kinase-Hemmer zur Behandlung von Krebs
JP2008506463A (ja) * 2004-07-14 2008-03-06 ゲーペーツェー ビオテック アーゲー 可変投与量パッケージシステム
CZ296169B6 (cs) * 2004-09-08 2006-01-11 Pliva - Lachema A. S. Farmaceutická kompozice pro rektální nebo vaginální podání, zpusob její prípravy a tato kompozice pro pouzití jako lécivo
CZ296459B6 (cs) * 2004-09-14 2006-03-15 Pliva-Lachema A. S. Perorální farmaceutická kompozice pro cílený transport komplexu platiny do kolorektální oblasti, zpusob její prípravy a tato kompozice pro pouzití jako lécivo
CA2587779A1 (en) * 2004-11-10 2007-01-18 University Of South Florida Platinum complexes for targeted drug delivery
WO2006090931A1 (ja) * 2005-02-28 2006-08-31 Eisai R & D Management Co., Ltd. スルホンアミド化合物の抗癌剤との新規併用
EP1792622A1 (de) 2005-11-11 2007-06-06 GPC Biotech AG Antiproliferative Kombinationstherapie mit einem Platin enthaltenden chemotherapeutischen Mittel und EGFR-Inhibitoren oder Pyrimidinanaloga
CZ300590B6 (cs) * 2006-06-20 2009-06-24 Pliva - Lachema A. S. Farmaceutická kompozice pro injekcní podání
CZ300120B6 (cs) * 2006-06-20 2009-02-11 Pliva - Lachema A. S. Farmaceutická kompozice pro injekcní podání
CZ300424B6 (cs) * 2006-06-20 2009-05-13 Pliva - Lachema A. S. Farmaceutická kompozice pro perorální podání
KR100829173B1 (ko) * 2006-09-19 2008-05-13 광주과학기술원 물에 대한 용해도가 우수한 플라틴 복합체의 포접복합체 및그 제조방법
GB2457453B (en) * 2008-02-12 2010-05-12 Pliva Lachema As Polymorphic crystalline form III of (OC-6-43)-bis(acetate)(1-tricyclo[3,3,1,13,7]decylamine) ammine dichloroplatinum (IV)
GB2457452B (en) * 2008-02-12 2010-05-12 Pliva Lachema As Amorphous form of (OC-6-43)-bis(acetate)(1-tricyclo[3,3,1,13,7]decylamine) amminedichloroplatinum (IV)
GB2457455B (en) * 2008-02-12 2010-04-21 Pliva Lachema As Polymorphic crystalline form (I) of (OC-6-43)-Bis(Acetato)-1-(Tricyclo[3,3,1,1 (3,7)]Decylamine)Amminedichloroplatinum(IV)
GB2457454B (en) * 2008-02-12 2010-05-12 Pliva Lachema As Polymorphic crystalline form II of (OC-6-43)-bis(acetate)(1-tricyclo[3,3,1,13,7]decylamine) ammine dichloroplatinum (IV)
WO2010149666A1 (en) 2009-06-22 2010-12-29 Medexis S.A. Methods for treating neoplasia
WO2011029639A2 (en) 2009-09-08 2011-03-17 Medexis S.A. Compounds and methods for treating neoplasia
WO2012013816A1 (en) 2010-07-30 2012-02-02 Medexis S.A. Compounds and methods for treating neoplasia
CA2957290C (en) * 2014-09-03 2020-07-14 Vuab Pharma A.S. Platinum (iv) complex with increased antitumor efficacy
CN104984356A (zh) * 2015-05-14 2015-10-21 昆明贵研药业有限公司 赛特铂的环糊精复合物及制备方法
RU2613513C2 (ru) * 2015-07-17 2017-03-16 Федеральное государственное бюджетное учреждение науки Институт проблем химической физики Российской академии наук (ИПХФ РАН) Способ получения комплексов платины (IV) с аминонитроксильными радикалами
RU2726826C2 (ru) * 2016-12-27 2020-07-15 Общество с ограниченной ответственностью "Плат-АН" (ООО "Плат-АН") Композиция на основе аминонитроксильного комплекса платины и доксорубицина и способ лечения опухолей
JP7386972B2 (ja) * 2019-09-05 2023-11-27 ブイユーエービー ファーマ エー．エス． 実質的に増加した抗腫瘍効果を有する新規白金ｉｖ錯体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0328274B1 (de) * 1988-02-02 1994-10-19 Johnson Matthey, Inc., Pt(IV) Komplexe
FI905018A7 (fi) * 1989-10-17 1991-04-18 Bristol Myers Squibb Co Veteen ja liuottimeen liukenevat aksiaaliset hydroksi- ja mono- ja di-karboksyylihappojohdannaiset, joilla on korkea kasvainaktiivisuus
GB9105037D0 (en) * 1991-03-09 1991-04-24 Johnson Matthey Plc Improvements in chemical compounds
RU2089555C1 (ru) * 1995-05-04 1997-09-10 Новосибирский институт биоорганической химии СО РАН Бисимидазол-(1,10)-фенантролинплатина (iii) дихлорид, проявляющий цитостатическую противоопухолевую активность
JPH10265380A (ja) * 1997-03-17 1998-10-06 Bristol Myers Squibb Co 抗ガン剤

Also Published As

Publication number Publication date
NO20005990D0 (no) 2000-11-27
YU71900A (sh) 2002-10-18
HUP0102549A2 (hu) 2001-11-28
HRP20000791B1 (en) 2006-07-31
JP2002516332A (ja) 2002-06-04
HRP20000791A2 (en) 2001-02-28
CA2332054A1 (en) 1999-12-02
EP1082330B1 (de) 2002-04-03
IL139529A0 (en) 2001-11-25
MXPA00011621A (es) 2003-03-12
BR9910669B1 (pt) 2011-07-26
CN1303388A (zh) 2001-07-11
HUP0102549A3 (en) 2004-04-28
SK17732000A3 (sk) 2001-05-10
NO20005990L (no) 2000-11-27
RS49738B (sr) 2008-04-04
BG64599B1 (bg) 2005-08-31
JP3575686B2 (ja) 2004-10-13
PL344346A1 (en) 2001-11-05
RU2200164C2 (ru) 2003-03-10
CA2332054C (en) 2005-06-28
UA56315C2 (uk) 2003-05-15
CZ288912B6 (cs) 2001-09-12
NO328930B1 (no) 2010-06-21
BG104972A (en) 2001-08-31
CZ162898A3 (cs) 1999-12-15
AU741380B2 (en) 2001-11-29
DE69901177T2 (de) 2002-10-02
IL139529A (en) 2004-06-20
PL191132B1 (pl) 2006-03-31
CN1124279C (zh) 2003-10-15
ES2175968T3 (es) 2002-11-16
WO1999061451A1 (en) 1999-12-02
US6503943B1 (en) 2003-01-07
BR9910669A (pt) 2001-01-30
PT1082330E (pt) 2002-09-30
AU3809399A (en) 1999-12-13
SK284436B6 (sk) 2005-04-01
HU224716B1 (en) 2006-01-30
EP1082330A1 (de) 2001-03-14
SI1082330T1 (en) 2002-08-31

Similar Documents

Publication Publication Date Title
DE69901177D1 (de) Platinkomplex, dessen herstellung und dessen therapeutische verwendung
DE60038200D1 (de) ren Herstellung und Verwendung
ATE249460T1 (de) 1,4-diazabicyclo(3.2.2)nonanderivate, deren herstellung und deren verwendung in heilkunde
DE69916828D1 (de) Pyrazoline, ihre herstellung und verwendung als medikamente
ATE284392T1 (de) Substituierte 2-phenylbenzimidazole, deren herstellung und anwendung
DE69529026D1 (de) Trehalose, ihre Herstellung und ihre Verwendung
ATE310003T1 (de) Benzodiazepin-derivate, deren herstellung und anwendung
DE10084441T1 (de) Koalinton-Pigmente, ihre Herstellung und Verwendung
DE69814431D1 (de) 3,3-diarylpropylamine , ihre verwendung und herstellung
ATE302604T1 (de) Thienylazolylalkoxyethanamine, deren herstellung und deren verwendung als medikamente
ATE261972T1 (de) 2,5-diazabicyclo(2.2.1)heptanderivate, deren herstellung und deren verwendung in heilkunde
ATE430734T1 (de) Isochinoline und deren herstellung
ATE308557T1 (de) Antipicornavirale verbindungen, deren herstellung und verwendung
DE69625857D1 (de) Siliconderivate, ihre Herstellung und Verwendung
ATE231869T1 (de) Pyridopyranoazepinderivate, ihre herstellung und therapeutische verwendung
DE59802590D1 (de) Cyclische Cedren-Acetale, ihre Herstellung und ihre Verwendung
DE60008419D1 (de) Farbstoffpräparate, deren herstellung und deren verwendung
DE60009155D1 (de) Substituierte phenyl-piperazin-derivate, deren herstellung und verwendung
ATE312828T1 (de) Acylaminothiazolderivate, deren herstellung und deren therapeutische verwendung
ATE265454T1 (de) Phenyloxazol-1,4-diazabicyclo(3.2.2)nonanderiva e,ihre herstellung und ihre therapeutische verwendung
ATE242197T1 (de) 3-amino-3-arylpropan-1-ol-derivate, deren herstellung und verwendung
ATE251170T1 (de) Titanverbindungen, deren herstellung und verwendung
DE69511579D1 (de) Biozide alkohole, ihre herstellung und ihre verwendung
DE59802922D1 (de) 3-substituierte tetrahydropyridopyrimidinon-derivate, ihre herstellung und verwendung
DE59711704D1 (de) Neue carbonsäurederivate, ihre herstellung und verwendung

Legal Events

Date Code Title Description
8364 No opposition during term of opposition