DE69838874D1 - Il-8 rezeptor-antagonisten - Google Patents
Il-8 rezeptor-antagonistenInfo
- Publication number
- DE69838874D1 DE69838874D1 DE69838874T DE69838874T DE69838874D1 DE 69838874 D1 DE69838874 D1 DE 69838874D1 DE 69838874 T DE69838874 T DE 69838874T DE 69838874 T DE69838874 T DE 69838874T DE 69838874 D1 DE69838874 D1 DE 69838874D1
- Authority
- DE
- Germany
- Prior art keywords
- receptor antagonists
- antagonists
- receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 108090001007 Interleukin-8 Proteins 0.000 title 1
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
- C07D275/06—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3599097P | 1997-01-23 | 1997-01-23 | |
| US35990P | 1997-01-23 | ||
| US4283097P | 1997-04-08 | 1997-04-08 | |
| US42830P | 1997-04-08 | ||
| PCT/US1998/001292 WO1998032438A1 (en) | 1997-01-23 | 1998-01-23 | Il-8 receptor antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69838874D1 true DE69838874D1 (de) | 2008-01-31 |
| DE69838874T2 DE69838874T2 (de) | 2008-12-04 |
Family
ID=26712686
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69838874T Expired - Fee Related DE69838874T2 (de) | 1997-01-23 | 1998-01-23 | Il-8 rezeptor-antagonisten |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US6166055A (de) |
| EP (1) | EP1005341B1 (de) |
| JP (1) | JP2002515055A (de) |
| KR (1) | KR20000070369A (de) |
| CN (1) | CN1253501A (de) |
| AR (1) | AR008331A1 (de) |
| AT (1) | ATE381330T1 (de) |
| AU (1) | AU729893B2 (de) |
| BR (1) | BR9807085A (de) |
| CA (1) | CA2278427A1 (de) |
| DE (1) | DE69838874T2 (de) |
| ES (1) | ES2299200T3 (de) |
| HU (1) | HUP0001940A3 (de) |
| IL (1) | IL131005A0 (de) |
| NO (1) | NO313913B1 (de) |
| NZ (1) | NZ336859A (de) |
| PE (1) | PE103699A1 (de) |
| PL (1) | PL334774A1 (de) |
| TR (1) | TR199901761T2 (de) |
| WO (1) | WO1998032438A1 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5929250A (en) * | 1997-01-23 | 1999-07-27 | Smithkline Beecham Corporation | IL-8 receptor antagonists |
| AR015426A1 (es) * | 1997-09-05 | 2001-05-02 | Smithkline Beecham Corp | Compuestos de benzotiazol antagonistas del receptor de il-8, composicion farmaceutica que los contiene, su uso para la manufactura de un medicamento,procedimiento para su preparacion, compuestos intermediarios y procedimiento para su preparacion |
| AR015425A1 (es) * | 1997-09-05 | 2001-05-02 | Smithkline Beecham Corp | Compuestos de benzotiazol, composicion farmaceutica que los contiene, su uso en la manufactura de un medicamento, procedimiento para su preparacion,compuestos intermediarios y procedimiento para su preparacion |
| EP1121360A4 (de) * | 1998-10-13 | 2002-01-23 | Smithkline Beecham Corp | Il-8-rezeptor-antagonisten |
| WO2000069435A1 (en) * | 1999-05-18 | 2000-11-23 | Smithkline Beecham Corporation | Il-8 receptor antagonists |
| CA2379359A1 (en) * | 1999-07-16 | 2001-01-25 | Basf Aktiengesellschaft | Process for the preparation of substituted benzisothiazole compounds |
| US6440993B1 (en) | 1999-10-12 | 2002-08-27 | Smithkline Beecham Corporation | IL-8 receptor antagonists |
| PE20011124A1 (es) | 2000-03-31 | 2001-10-28 | Upjohn Co | Nuevos agentes antibacterianos de benzosultam oxazolidinona |
| DE10038709A1 (de) | 2000-08-09 | 2002-02-28 | Aventis Pharma Gmbh | Substituierte und unsubstituierte Benzooxathiazole sowie daraus abgeleitete Verbindungen |
| GB0403038D0 (en) | 2004-02-11 | 2004-03-17 | Novartis Ag | Organic compounds |
| WO2005113534A2 (en) | 2004-05-12 | 2005-12-01 | Schering Corporation | Cxcr1 and cxcr2 chemokine antagonists |
| AR065369A1 (es) | 2007-02-19 | 2009-06-03 | Novartis Ag | Derivados de ciclohexil - amida del acido aril- carboxilico |
| RU2654484C1 (ru) | 2012-05-11 | 2018-05-21 | Ресет Терапьютикс, Инк. | Карбазолсодержащие сульфонамиды в качестве модуляторов криптохрома |
| TWI690521B (zh) | 2014-04-07 | 2020-04-11 | 美商同步製藥公司 | 作為隱花色素調節劑之含有咔唑之醯胺類、胺基甲酸酯類及脲類 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5795887A (en) * | 1994-04-15 | 1998-08-18 | Glaxo Wellcome Inc. | Method of inducing cholecystokinin agonist activity using 1,4- Benzodiazepine compounds |
| JP3720395B2 (ja) * | 1994-09-20 | 2005-11-24 | 京都薬品工業株式会社 | 新規ヘテロ環誘導体、その製造方法およびその医薬用途 |
| WO1997012860A1 (en) * | 1995-10-05 | 1997-04-10 | Kyoto Pharmaceutical Industries, Ltd. | Novel heterocyclic derivatives and medicinal use thereof |
| US5929250A (en) * | 1997-01-23 | 1999-07-27 | Smithkline Beecham Corporation | IL-8 receptor antagonists |
| AR015426A1 (es) * | 1997-09-05 | 2001-05-02 | Smithkline Beecham Corp | Compuestos de benzotiazol antagonistas del receptor de il-8, composicion farmaceutica que los contiene, su uso para la manufactura de un medicamento,procedimiento para su preparacion, compuestos intermediarios y procedimiento para su preparacion |
| AR015425A1 (es) * | 1997-09-05 | 2001-05-02 | Smithkline Beecham Corp | Compuestos de benzotiazol, composicion farmaceutica que los contiene, su uso en la manufactura de un medicamento, procedimiento para su preparacion,compuestos intermediarios y procedimiento para su preparacion |
| WO1999036069A1 (en) * | 1998-01-16 | 1999-07-22 | Smithkline Beecham Corporation | Il-8 receptor antagonists |
-
1998
- 1998-01-22 AR ARP980100284A patent/AR008331A1/es not_active Application Discontinuation
- 1998-01-23 PL PL98334774A patent/PL334774A1/xx unknown
- 1998-01-23 HU HU0001940A patent/HUP0001940A3/hu unknown
- 1998-01-23 KR KR1019997006602A patent/KR20000070369A/ko not_active Ceased
- 1998-01-23 EP EP98901852A patent/EP1005341B1/de not_active Expired - Lifetime
- 1998-01-23 BR BR9807085-1A patent/BR9807085A/pt not_active Application Discontinuation
- 1998-01-23 TR TR1999/01761T patent/TR199901761T2/xx unknown
- 1998-01-23 AU AU58278/98A patent/AU729893B2/en not_active Ceased
- 1998-01-23 US US09/341,382 patent/US6166055A/en not_active Expired - Fee Related
- 1998-01-23 DE DE69838874T patent/DE69838874T2/de not_active Expired - Fee Related
- 1998-01-23 ES ES98901852T patent/ES2299200T3/es not_active Expired - Lifetime
- 1998-01-23 JP JP53213998A patent/JP2002515055A/ja not_active Ceased
- 1998-01-23 IL IL13100598A patent/IL131005A0/xx unknown
- 1998-01-23 NZ NZ336859A patent/NZ336859A/xx unknown
- 1998-01-23 CN CN98803564A patent/CN1253501A/zh active Pending
- 1998-01-23 AT AT98901852T patent/ATE381330T1/de not_active IP Right Cessation
- 1998-01-23 WO PCT/US1998/001292 patent/WO1998032438A1/en not_active Ceased
- 1998-01-23 CA CA002278427A patent/CA2278427A1/en not_active Abandoned
- 1998-07-22 PE PE1998000656A patent/PE103699A1/es not_active Application Discontinuation
-
1999
- 1999-07-22 NO NO19993585A patent/NO313913B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US6166055A (en) | 2000-12-26 |
| BR9807085A (pt) | 2000-04-18 |
| EP1005341A1 (de) | 2000-06-07 |
| NZ336859A (en) | 2001-01-26 |
| PE103699A1 (es) | 1999-12-30 |
| TR199901761T2 (xx) | 1999-10-21 |
| PL334774A1 (en) | 2000-03-13 |
| AR008331A1 (es) | 1999-12-29 |
| WO1998032438A1 (en) | 1998-07-30 |
| AU729893B2 (en) | 2001-02-15 |
| EP1005341B1 (de) | 2007-12-19 |
| AU5827898A (en) | 1998-08-18 |
| ES2299200T3 (es) | 2008-05-16 |
| IL131005A0 (en) | 2001-01-28 |
| KR20000070369A (ko) | 2000-11-25 |
| HUP0001940A3 (en) | 2002-09-30 |
| NO993585L (no) | 1999-09-21 |
| JP2002515055A (ja) | 2002-05-21 |
| CN1253501A (zh) | 2000-05-17 |
| EP1005341A4 (de) | 2004-09-08 |
| NO313913B1 (no) | 2002-12-23 |
| NO993585D0 (no) | 1999-07-22 |
| HUP0001940A2 (hu) | 2001-01-29 |
| DE69838874T2 (de) | 2008-12-04 |
| ATE381330T1 (de) | 2008-01-15 |
| CA2278427A1 (en) | 1998-07-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |