DE69803653D1 - 1,3,8-Triazaspiro[4,5]decan-4-on-derivate - Google Patents

1,3,8-Triazaspiro[4,5]decan-4-on-derivate

Info

Publication number: DE69803653D1
Authority: DE; Germany
Prior art keywords: triazaspiro; decan; derivatives
Prior art date: 1997-12-05
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE69803653T

Other languages

English (en)

Other versions

DE69803653T2 (de

Inventor

Geo Adam

Andrea Cesura

Guido Galley

Francois Jenck

Stephan Roever

Juergen Wichmann

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

F Hoffmann La Roche AG

Original Assignee

F Hoffmann La Roche AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-12-05

Filing date

1998-11-27

Publication date

2002-03-14

1998-11-27 Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG

2002-03-14 Publication of DE69803653D1 publication Critical patent/DE69803653D1/de

2002-08-29 Application granted granted Critical

2002-08-29 Publication of DE69803653T2 publication Critical patent/DE69803653T2/de

2018-11-28 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Child & Adolescent Psychology (AREA)
Addiction (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Color Printing (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

DE69803653T 1997-12-05 1998-11-27 1,3,8-Triazaspiro[4,5]decan-4-on-derivate Expired - Lifetime DE69803653T2 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP97121427		1997-12-05

Publications (2)

Publication Number	Publication Date
DE69803653D1 true DE69803653D1 (de)	2002-03-14
DE69803653T2 DE69803653T2 (de)	2002-08-29

Family

ID=8227753

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69803653T Expired - Lifetime DE69803653T2 (de)	1997-12-05	1998-11-27	1,3,8-Triazaspiro[4,5]decan-4-on-derivate

Country Status (29)

Country	Link
US (1)	US6043366A (de)
JP (1)	JP3366868B2 (de)
KR (1)	KR19990062800A (de)
CN (1)	CN1118467C (de)
AR (1)	AR016428A1 (de)
AT (1)	ATE212635T1 (de)
AU (1)	AU744338B2 (de)
BR (1)	BR9805297B1 (de)
CA (1)	CA2255171C (de)
CO (1)	CO4990965A1 (de)
CZ (1)	CZ399698A3 (de)
DE (1)	DE69803653T2 (de)
DK (1)	DK0921125T3 (de)
ES (1)	ES2170446T3 (de)
HR (1)	HRP980613A2 (de)
HU (1)	HUP9802807A3 (de)
ID (1)	ID21413A (de)
IL (1)	IL127399A0 (de)
MA (1)	MA26573A1 (de)
NO (1)	NO312161B1 (de)
NZ (1)	NZ333159A (de)
PE (1)	PE135299A1 (de)
PL (1)	PL330062A1 (de)
PT (1)	PT921125E (de)
SG (1)	SG71173A1 (de)
TR (1)	TR199802520A3 (de)
TW (1)	TW408123B (de)
YU (1)	YU55198A (de)
ZA (1)	ZA9811128B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0997464B1 (de) *	1998-10-23	2005-02-16	Pfizer Inc.	1,3,8-Triazaspiro[4,5] decanon Verbindungen als orl1-receptor Agonisten
EP1537110B1 (de) *	1999-12-06	2007-01-17	Euro-Celtique, S.A.	Triazospiroverbindungen mit nociceptin-rezeptoraffinität
US7192964B2 (en) *	2001-07-23	2007-03-20	Banyu Pharmaceutical Co., Ltd.	4-oxoimidazolidine-2-spiropiperidine derivatives
AU2003220886A1 (en)	2002-03-29	2003-10-13	Mitsubishi Pharma Corporation	Remedy for sleep disturbance
MXPA05002622A (es) *	2002-09-09	2005-09-08	Johnson & Johnson	Derivados de 1,3,8,-triazaespiro [4.5]decan-4-ona sustituidos con hidroxialquilo utiles para el tratamiento de desordenes mediados por el receptor opioide huerfano.
WO2004058727A1 (en) *	2002-12-20	2004-07-15	Bayer Pharmaceuticals Corporation	Substituted 3,5-dihydro-4h-imidazol-4-ones for the treatment of obesity
NZ544282A (en) *	2003-05-23	2009-07-31	Zealand Pharma As	Triaza-spiro compounds as nociceptin analogues and uses thereof
BRPI0415833A (pt) *	2003-10-23	2007-01-02	Hoffmann La Roche	derivados de triaza-espiropiperidina para uso como inibidores de glyt-1 no tratamento de distúrbios neurológicos e neuropsiquiátricos
US20060178390A1 (en) *	2004-08-02	2006-08-10	Alfonzo Jordan	1,3,8-Triazaspiro[4,5]decan-4-one derivatives useful for the treatment of ORL-1 receptor mediated disorders
AU2006226447B2 (en) *	2005-03-22	2009-07-16	F. Hoffmann-La Roche Ag	New salt and polymorphs of a DPP-IV inhibitor
AR061522A1 (es) *	2006-06-20	2008-09-03	Wyeth Corp	Derivados de 4-oxo-1, 3, 8-triaza[4.5]decanos como inhibidores del canal de potasio kv1.5, una composicion que los comprende y su empleo en el tratamiento de afecciones cardiacas.
US8703948B2 (en) *	2006-11-28	2014-04-22	Janssen Pharmaceutica Nv	Salts of 3-(3-amino-2-(R)-hydroxy-propyl)-1-(4-fluoro-phenyl)-8-(8-methyl-naphthalen-1-ylmethyl)-1,3,8-triaza-spiro[4.5]decan-4-one
CA2679530C (en) *	2007-03-01	2012-09-25	Mitsubishi Tanabe Pharma Corporation	Benzimidazole compound and pharmaceutical use thereof
JP5490677B2 (ja) *	2007-04-09	2014-05-14	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	不安及び鬱病の処置のためのｏｒｌ−１受容体リガンドとしての１，３，８−三置換−１，３，８−トリアザ−スピロ［４．５］デカン−４−オン誘導体
PA8801401A1 (es) *	2007-10-25	2009-05-15	Janssen Pharmaceutica Nv	Arilindenopirimidinas y su uso como adenosina a2a
TW201016675A (en) *	2008-09-16	2010-05-01	Mitsubishi Tanabe Pharma Corp	Crystalline benzoimidazole compound and salt thereof
US20100076003A1 (en) *	2008-09-19	2010-03-25	Kathleen Battista	5-oxazolidin-2-one substituted 1,3,8-triazaspiro[4.5]decan-4-one derivatives useful as orl-1 receptor modulators
WO2010037081A1 (en) *	2008-09-29	2010-04-01	Palatin Technologies, Inc.	Melanocortin receptor-specific spiro-piperidine compounds
JP2012530136A (ja)	2009-06-16	2012-11-29	メルク・シャープ・エンド・ドーム・コーポレイション	置換−１，３，８−トリアザスピロ［４．５］デカン−２，４−ジオン
WO2017005583A1 (en) *	2015-07-03	2017-01-12	F. Hoffmann-La Roche Ag	Triaza-spirodecanones as ddr1 inhibitors
US20230357168A1 (en) *	2022-04-15	2023-11-09	The Chinese University Of Hong Kong	Carbobicyclic nucleosides for treatment of viral infection

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3155669A (en) *	1962-06-22	1964-11-03	Res Lab Dr C Janssen N V	2, 4, 8-triaza-spiro (4, 5) dec-2-enes
US3155670A (en) *	1962-06-22	1964-11-03	Res Lab Dr C Janssen N V	1-oxo-2, 4, 8, triaza-spiro (4, 5) decanes
US3161644A (en) *	1962-06-22	1964-12-15	Res Lab Dr C Janssen N V	1-benzyl-4-substituted piperidines
US3238216A (en) *	1963-06-20	1966-03-01	Res Lab Dr C Janssen N V	Substituted 1, 3, 8-triaza-spiro (4, 5) decanes
JPS51100084A (de) *	1975-02-28	1976-09-03	Yoshitomi Pharmaceutical
GB1486546A (en) *	1975-02-28	1977-09-21	Yoshitomo Pharma Ind Ltd	4,4-diphenyl-cyclohexylpiperidine compounds and analogues thereof
JPS5212171A (en) *	1975-07-17	1977-01-29	Yoshitomi Pharmaceut Ind Ltd	Process for preparation of cyclohexane derivatives
JPS5934713B2 (ja) *	1976-01-05	1984-08-24	ウェルファイド株式会社	脂環式誘導体
US4076821A (en) *	1976-02-27	1978-02-28	Yoshitomi Pharmaceutical Industries, Ltd.	4,4-Diphenylcycloalkylpiperidines and psychotropic compositions thereof
MA19091A1 (fr) *	1980-03-10	1981-10-01	Janssen Pharmaceutica Nv	Nouveaux derives de i-(4-aryl-cyclohexyl)piperidine .
GR73633B (de) *	1980-03-10	1984-03-26	Janssen Pharmaceutica Nv
US4329353A (en) *	1980-10-22	1982-05-11	Janssen Pharmaceutica, N.V.	1-(4-Aryl-cyclohexyl)piperidine derivatives, method of use thereof and pharmaceutical compositions thereof
EP0114787B1 (de) *	1983-01-25	1991-09-25	Ciba-Geigy Ag	Neue Peptidderivate
JPS6012357B2 (ja) *	1984-01-23	1985-04-01	吉富製薬株式会社	脂環式誘導体
CA2226058C (en) *	1997-01-30	2008-01-29	F. Hoffmann-La Roche Ag	8-substituted-1,3,8-triaza-spiro[4.5]decan-4-one derivatives

1998
- 1998-11-27 ES ES98122511T patent/ES2170446T3/es not_active Expired - Lifetime
- 1998-11-27 DK DK98122511T patent/DK0921125T3/da active
- 1998-11-27 PT PT98122511T patent/PT921125E/pt unknown
- 1998-11-27 AT AT98122511T patent/ATE212635T1/de active
- 1998-11-27 DE DE69803653T patent/DE69803653T2/de not_active Expired - Lifetime
- 1998-12-03 US US09/204,184 patent/US6043366A/en not_active Expired - Fee Related
- 1998-12-03 ID IDP981576A patent/ID21413A/id unknown
- 1998-12-03 NZ NZ333159A patent/NZ333159A/en unknown
- 1998-12-03 PL PL98330062A patent/PL330062A1/xx unknown
- 1998-12-03 AR ARP980106141A patent/AR016428A1/es active IP Right Grant
- 1998-12-03 CA CA002255171A patent/CA2255171C/en not_active Expired - Fee Related
- 1998-12-03 PE PE1998001176A patent/PE135299A1/es not_active Application Discontinuation
- 1998-12-03 SG SG1998005141A patent/SG71173A1/en unknown
- 1998-12-03 YU YU55198A patent/YU55198A/sh unknown
- 1998-12-04 JP JP34527898A patent/JP3366868B2/ja not_active Expired - Fee Related
- 1998-12-04 IL IL12739998A patent/IL127399A0/xx unknown
- 1998-12-04 CO CO98072457A patent/CO4990965A1/es unknown
- 1998-12-04 AU AU96087/98A patent/AU744338B2/en not_active Ceased
- 1998-12-04 TW TW087120132A patent/TW408123B/zh not_active IP Right Cessation
- 1998-12-04 HU HU9802807A patent/HUP9802807A3/hu unknown
- 1998-12-04 MA MA25369A patent/MA26573A1/fr unknown
- 1998-12-04 CZ CZ983996A patent/CZ399698A3/cs unknown
- 1998-12-04 CN CN98122759A patent/CN1118467C/zh not_active Expired - Fee Related
- 1998-12-04 HR HR97121427.5A patent/HRP980613A2/hr not_active Application Discontinuation
- 1998-12-04 BR BRPI9805297-7A patent/BR9805297B1/pt not_active IP Right Cessation
- 1998-12-04 KR KR1019980053080A patent/KR19990062800A/ko not_active Ceased
- 1998-12-04 TR TR1998/02520A patent/TR199802520A3/tr unknown
- 1998-12-04 ZA ZA9811128A patent/ZA9811128B/xx unknown
- 1998-12-04 NO NO19985684A patent/NO312161B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
JP3366868B2 (ja)	2003-01-14
AU9608798A (en)	1999-06-24
TW408123B (en)	2000-10-11
ATE212635T1 (de)	2002-02-15
NO985684D0 (no)	1998-12-04
KR19990062800A (ko)	1999-07-26
PT921125E (pt)	2002-06-28
HUP9802807A3 (en)	2000-01-28
BR9805297A (pt)	2000-02-01
IL127399A0 (en)	1999-10-28
CZ399698A3 (cs)	1999-06-16
CN1118467C (zh)	2003-08-20
HRP980613A2 (en)	1999-08-31
NZ333159A (en)	2000-06-23
HUP9802807A2 (hu)	1999-08-30
YU55198A (sh)	2001-12-26
CO4990965A1 (es)	2000-12-26
NO985684L (no)	1999-06-07
US6043366A (en)	2000-03-28
BR9805297B1 (pt)	2010-07-13
TR199802520A2 (xx)	1999-06-21
NO312161B1 (no)	2002-04-02
TR199802520A3 (tr)	1999-06-21
CN1222521A (zh)	1999-07-14
ZA9811128B (en)	1999-06-07
PE135299A1 (es)	2000-01-18
CA2255171A1 (en)	1999-06-05
HU9802807D0 (en)	1999-02-01
AU744338B2 (en)	2002-02-21
JPH11228575A (ja)	1999-08-24
PL330062A1 (en)	1999-06-07
CA2255171C (en)	2009-09-29
DK0921125T3 (da)	2002-05-13
ES2170446T3 (es)	2002-08-01
AR016428A1 (es)	2001-07-04
MA26573A1 (fr)	2004-12-20
DE69803653T2 (de)	2002-08-29
ID21413A (id)	1999-06-10
SG71173A1 (en)	2000-03-21

Publication	Publication Date	Title
DE69800896D1 (de)	2001-07-19	8-substituierte-1,3,8-Triazaspiro[4,5]decan-4-onderivate
DE69803653D1 (de)	2002-03-14	1,3,8-Triazaspiro[4,5]decan-4-on-derivate
ATE236155T1 (de)	2003-04-15	Naphthyridin-derivate
SI0921125T1 (en)	2002-04-30	1,3,8-Triazaspiro(4,5)decan-4-on derivatives
IS4570A (is)	1997-09-25	Imidazó[1,2-a]pýridín afleiður
DE69804273D1 (de)	2002-04-25	5h-Thiazolo[3,2-a]pyrimidinderivate
CZ20011556A3 (cs)	2001-11-14	Pyrazolopyridinové deriváty
PL334847A1 (en)	2000-03-27	Substituted 3-heterocyclyl-benzoyl derivatives
ATE215950T1 (de)	2002-04-15	Carbolinderivate
NO20013384D0 (no)	2001-07-06	Imidazo[4,5-c]pyridin-4-on-derivater
DE69900220D1 (de)	2001-09-20	Diaza-spiro[3,5]nonan-Derivate
HUP0003692A3 (en)	2002-10-28	Pyrimido[4,5-b]indolyl-alkanecarboxamide derivatives
DE69905798D1 (de)	2003-04-17	Di- oder Triazaspiro[4,5]decanderivate
ZA985559B (en)	1999-01-20	Tetrahydroimidazo Ä2,1-aÜsoquinoline derivatives
DE69515498D1 (de)	2000-04-13	Naphthyridinderivate
PT1010699E (pt)	2005-08-31	Derivados de 3-oxadiazolil-1,6-naftiridina-2(h)-ona substituido em 5
GB2308593B (en)	1999-01-27	Imidazopyridine derivatives
GB9608592D0 (en)	1996-07-03	Imidazopyridine derivatives
ZA966559B (en)	1997-02-19	Imidazopyridine derivatives.
IL121360A0 (en)	1998-01-04	Imidazopyridine derivatives

Legal Events

Date	Code	Title	Description
2003-02-27	8364	No opposition during term of opposition