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DE69703689D1 - Therapeutische anwendungen von bpi-protein-produkten zur behandlung von humaner meningococcämia - Google Patents

Therapeutische anwendungen von bpi-protein-produkten zur behandlung von humaner meningococcämia

Info

Publication number
DE69703689D1
DE69703689D1 DE69703689T DE69703689T DE69703689D1 DE 69703689 D1 DE69703689 D1 DE 69703689D1 DE 69703689 T DE69703689 T DE 69703689T DE 69703689 T DE69703689 T DE 69703689T DE 69703689 D1 DE69703689 D1 DE 69703689D1
Authority
DE
Germany
Prior art keywords
meningococcämia
protein products
bpi protein
therapeutic applications
treating human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69703689T
Other languages
English (en)
Other versions
DE69703689T2 (de
Inventor
P Giroir
J Scannon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Xoma Technology Ltd USA
Original Assignee
Xoma Technology Ltd USA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xoma Technology Ltd USA filed Critical Xoma Technology Ltd USA
Application granted granted Critical
Publication of DE69703689D1 publication Critical patent/DE69703689D1/de
Publication of DE69703689T2 publication Critical patent/DE69703689T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4742—Bactericidal/Permeability-increasing protein [BPI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1751—Bactericidal/permeability-increasing protein [BPI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69703689T 1996-05-10 1997-05-09 Therapeutische anwendungen von bpi-protein-produkten zur behandlung von humaner meningococcämia Expired - Fee Related DE69703689T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64428796A 1996-05-10 1996-05-10
PCT/US1997/008016 WO1997042966A1 (en) 1996-05-10 1997-05-09 Therapeutic uses of bpi protein products for human meningococcemia

Publications (2)

Publication Number Publication Date
DE69703689D1 true DE69703689D1 (de) 2001-01-18
DE69703689T2 DE69703689T2 (de) 2001-05-10

Family

ID=24584256

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69703689T Expired - Fee Related DE69703689T2 (de) 1996-05-10 1997-05-09 Therapeutische anwendungen von bpi-protein-produkten zur behandlung von humaner meningococcämia

Country Status (14)

Country Link
US (4) US5888977A (de)
EP (1) EP0914144B1 (de)
JP (1) JP2000510845A (de)
CN (1) CN1236320A (de)
AT (1) ATE198050T1 (de)
AU (1) AU735058B2 (de)
CA (1) CA2253837C (de)
DE (1) DE69703689T2 (de)
DK (1) DK0914144T3 (de)
ES (1) ES2153665T3 (de)
GR (1) GR3035440T3 (de)
NZ (2) NZ505070A (de)
PT (1) PT914144E (de)
WO (1) WO1997042966A1 (de)

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US5198541A (en) * 1987-08-11 1993-03-30 New York University Dna encoding bactericidal/permeability-increasing proteins
US6214789B1 (en) * 1993-03-12 2001-04-10 Xoma Corporation Treatment of mycobacterial diseases by administration of bactericidal/permeability-increasing protein products
US5652332A (en) * 1993-03-12 1997-07-29 Xoma Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof
US6071274A (en) 1996-12-19 2000-06-06 Ep Technologies, Inc. Loop structures for supporting multiple electrode elements
US6464700B1 (en) 1994-10-07 2002-10-15 Scimed Life Systems, Inc. Loop structures for positioning a diagnostic or therapeutic element on the epicardium or other organ surface
WO1997004008A1 (en) * 1995-07-20 1997-02-06 Xoma Corporation Anti-fungal peptides
CA2253837C (en) * 1996-05-10 2002-07-02 Xoma Corporation Therapeutic uses of bpi protein products for human meningococcemia
US5888973A (en) 1996-08-09 1999-03-30 Xoma Corporation Anti-chlamydial uses of BPI protein products
US6482796B2 (en) 1996-11-01 2002-11-19 Xoma Corporation Therapeutic uses of N-terminal BPI protein products in ANCA-positive patients
US6203525B1 (en) 1996-12-19 2001-03-20 Ep Technologies, Inc. Catheterdistal assembly with pull wires
US6048329A (en) * 1996-12-19 2000-04-11 Ep Technologies, Inc. Catheter distal assembly with pull wires
US6071279A (en) 1996-12-19 2000-06-06 Ep Technologies, Inc. Branched structures for supporting multiple electrode elements
US6332880B1 (en) 1996-12-19 2001-12-25 Ep Technologies, Inc. Loop structures for supporting multiple electrode elements
US6093573A (en) * 1997-06-20 2000-07-25 Xoma Three-dimensional structure of bactericidal/permeability-increasing protein (BPI)
US6610055B1 (en) 1997-10-10 2003-08-26 Scimed Life Systems, Inc. Surgical method for positioning a diagnostic or therapeutic element on the epicardium or other organ surface
DE69937419T2 (de) * 1998-05-01 2008-07-24 Novartis Vaccines and Diagnostics, Inc., Emeryville Neisseria Meningitidis Antigene und Zusammenstellungen
US6013631A (en) 1998-06-19 2000-01-11 Xoma Corporation Bactericidal/permeability-increasing protein (BPI) deletion analogs
MXPA01007031A (es) * 1999-01-22 2004-08-12 Xoma Technology Ltd Metodo para tratar enfermedades acrdiacas cronicas.
US6217528B1 (en) 1999-02-11 2001-04-17 Scimed Life Systems, Inc. Loop structure having improved tissue contact capability
US6529756B1 (en) 1999-11-22 2003-03-04 Scimed Life Systems, Inc. Apparatus for mapping and coagulating soft tissue in or around body orifices
US6645199B1 (en) 1999-11-22 2003-11-11 Scimed Life Systems, Inc. Loop structures for supporting diagnostic and therapeutic elements contact with body tissue and expandable push devices for use with same
US6542781B1 (en) 1999-11-22 2003-04-01 Scimed Life Systems, Inc. Loop structures for supporting diagnostic and therapeutic elements in contact with body tissue
US6613046B1 (en) 1999-11-22 2003-09-02 Scimed Life Systems, Inc. Loop structures for supporting diagnostic and therapeutic elements in contact with body tissue
US20010048951A1 (en) * 2000-04-14 2001-12-06 Hal Sternberg Methods of administering a synthetic plasma like solution, and systems and kits for use in practicing the same
CA2430588A1 (en) * 2000-12-01 2002-07-18 Xoma Technology Ltd. Modulation of pericyte proliferation using bpi protein products or bpi inhibitors
EP1741440A1 (de) 2005-07-08 2007-01-10 Mellitus S.L. Verwendung von BPI-proteine zur Behandlung von stoffwechselbedingten Erkrankungen und Herzkreislaufstörungen
EP2265310A2 (de) * 2008-04-09 2010-12-29 Microlin, LLC Vorrichtung und verfahren für transdermale sauerstofffreisetzung
DE102010015682B4 (de) 2010-04-21 2014-01-02 Peter Arnold Vorrichtung zum Erfassen der Prozessstrahlung bei der Lasermaterialbearbeitung
GB201319620D0 (en) 2013-11-06 2013-12-18 Norwegian University Of Science And Technology Immunosuppressive agents and their use in therapy
GB201319621D0 (en) 2013-11-06 2013-12-18 Norwegian University Of Science And Technology Antimicrobial agents and their use in therapy

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US5245013A (en) * 1985-04-30 1993-09-14 Richard Ulevitch Acute phase protein modulating endotoxic activity of lipopolysaccharides, assay methods and polypeptides
US5198541A (en) * 1987-08-11 1993-03-30 New York University Dna encoding bactericidal/permeability-increasing proteins
US5576292A (en) * 1987-08-11 1996-11-19 New York University Biologically active bactericidal/permeability-increasing protein fragments
US5334584A (en) * 1989-02-14 1994-08-02 Incyte Pharamaceuticals, Inc. Recombinant, non-glycosylated bpi protein and uses thereof
US5308834A (en) * 1989-02-14 1994-05-03 Incyte Pharmaceuticals, Inc. Treatment of endotoxin-associated shock and prevention thereof using a BPI protein
US5089274A (en) * 1989-02-14 1992-02-18 Incyte Pharmaceuticals, Inc. Use of bactericidal/permeability increasing protein or biologically active analogs thereof to treat endotoxin-related disorders
US5171739A (en) * 1989-02-14 1992-12-15 Incyte Pharmaceuticals, Inc. Treatment of endotoxin-associated shock and preventation thereof using a BPI protein
US5234912A (en) * 1989-02-14 1993-08-10 Incyte Pharmaceuticals, Inc. Pharmaceutical compositions comprising recombinant BPI proteins and a lipid carrier and uses thereof
WO1991001639A1 (en) * 1989-08-01 1991-02-21 Scripps Clinic And Research Foundation Methods and compositions for ameliorating the symptoms of sepsis
DE69128968T2 (de) * 1990-12-03 1998-10-08 Univ New York Biologisch aktive bakterizide/permeabilitätserhöhende proteinbruchstücke
JPH07502642A (ja) * 1991-09-26 1995-03-23 インサイト　ファーマシューティカルズ，インコーポレイテッド 新規な形態のリポ糖結合性タンパク質（ｌｂｐ）
US5643570A (en) * 1992-05-19 1997-07-01 Xoma Corporation BPI-immunoglobulin fusion proteins
AU669723B2 (en) * 1992-05-19 1996-06-20 Xoma Corporation Improved methods for the preparation of endotoxin-binding proteins
US5488034A (en) * 1993-02-02 1996-01-30 Xoma Corporation Pharmaceutical composition comprising BPI proteins
US5420019A (en) * 1993-02-02 1995-05-30 Xoma Corporation Stable bactericidal/permeability-increasing protein muteins
US5733872A (en) * 1993-03-12 1998-03-31 Xoma Corporation Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof
CA2158058C (en) * 1993-03-12 2000-08-01 Roger G. Ii Little Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof
ES2157981T3 (es) * 1993-03-12 2001-09-01 Xoma Technology Ltd Usos terapeuticos de productos proteicos bactericidas/aumentadores de la permeabilidad.
US5348942A (en) * 1993-03-12 1994-09-20 Xoma Corporation Therapeutic uses of bactericidal/permeability increasing protein products
WO1994020129A1 (en) * 1993-03-12 1994-09-15 Xoma Corporation Treatment of mycobacterial diseases by administration of bactericidal/permeability-increasing protein products
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JPH08511682A (ja) * 1993-04-30 1996-12-10 インサイト ファーマシューティカルズ，インク． 組み換えｂｐｉ蛋白およびｌｂｐ蛋白、それをコードする核酸分子、その生産方法並びにそれらの使用
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US5643875A (en) * 1994-01-24 1997-07-01 Friedmann; Nadav Human therapeutic uses of bactericidal/permeability increasing (BPI) protein products
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Also Published As

Publication number Publication date
DE69703689T2 (de) 2001-05-10
CA2253837A1 (en) 1997-11-20
NZ332720A (en) 2000-07-28
CN1236320A (zh) 1999-11-24
EP0914144A1 (de) 1999-05-12
GR3035440T3 (en) 2001-05-31
WO1997042966A1 (en) 1997-11-20
DK0914144T3 (da) 2001-04-09
CA2253837C (en) 2002-07-02
NZ505070A (en) 2005-01-28
US6242418B1 (en) 2001-06-05
JP2000510845A (ja) 2000-08-22
ES2153665T3 (es) 2001-03-01
AU735058B2 (en) 2001-06-28
ATE198050T1 (de) 2000-12-15
US5888977A (en) 1999-03-30
US6596691B2 (en) 2003-07-22
US5990086A (en) 1999-11-23
US20020103114A1 (en) 2002-08-01
HK1019856A1 (en) 2000-03-03
EP0914144B1 (de) 2000-12-13
PT914144E (pt) 2001-05-31
AU3004397A (en) 1997-12-05

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: XOMA TECHNOLOGY LTD., BERKELEY, CALIF., US BOARD O

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee