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DE69635783D1 - Antigen omp26 aus haemophilus influenzae - Google Patents

Antigen omp26 aus haemophilus influenzae

Info

Publication number
DE69635783D1
DE69635783D1 DE69635783T DE69635783T DE69635783D1 DE 69635783 D1 DE69635783 D1 DE 69635783D1 DE 69635783 T DE69635783 T DE 69635783T DE 69635783 T DE69635783 T DE 69635783T DE 69635783 D1 DE69635783 D1 DE 69635783D1
Authority
DE
Germany
Prior art keywords
methods
influenzae
omp26
antigen
haemophilus influenzae
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69635783T
Other languages
English (en)
Other versions
DE69635783T2 (de
Inventor
Jennelle Kyd
Allan Cripps
John Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CORTECS INTERNAT Ltd
Original Assignee
CORTECS INTERNAT Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CORTECS INTERNAT Ltd filed Critical CORTECS INTERNAT Ltd
Application granted granted Critical
Publication of DE69635783D1 publication Critical patent/DE69635783D1/de
Publication of DE69635783T2 publication Critical patent/DE69635783T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/285Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/102Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/975Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
DE69635783T 1995-06-27 1996-06-27 Antigen omp26 aus haemophilus influenzae Expired - Lifetime DE69635783T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9513074.6A GB9513074D0 (en) 1995-06-27 1995-06-27 Novel anigen
GB9513074 1995-06-27
PCT/GB1996/001549 WO1997001638A1 (en) 1995-06-27 1996-06-27 Omp26 antigen from haemophilus influenzae

Publications (2)

Publication Number Publication Date
DE69635783D1 true DE69635783D1 (de) 2006-04-13
DE69635783T2 DE69635783T2 (de) 2006-11-02

Family

ID=10776746

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69635783T Expired - Lifetime DE69635783T2 (de) 1995-06-27 1996-06-27 Antigen omp26 aus haemophilus influenzae

Country Status (18)

Country Link
US (4) US6245338B1 (de)
EP (1) EP0835313B1 (de)
JP (2) JPH11510373A (de)
KR (1) KR19990028423A (de)
CN (1) CN1144875C (de)
AT (1) ATE317013T1 (de)
AU (1) AU708061B2 (de)
CA (1) CA2225405A1 (de)
DE (1) DE69635783T2 (de)
ES (1) ES2259443T3 (de)
GB (1) GB9513074D0 (de)
MX (1) MX9710412A (de)
NO (1) NO976119L (de)
NZ (1) NZ311120A (de)
RU (1) RU2221045C2 (de)
TW (1) TW457247B (de)
WO (1) WO1997001638A1 (de)
ZA (1) ZA965482B (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6355450B1 (en) 1995-04-21 2002-03-12 Human Genome Sciences, Inc. Computer readable genomic sequence of Haemophilus influenzae Rd, fragments thereof, and uses thereof
US6468765B1 (en) 1995-04-21 2002-10-22 Human Genome Sciences, Inc. Selected Haemophilus influenzae Rd polynucleotides and polypeptides
GB9904183D0 (en) * 1999-02-24 1999-04-14 Smithkline Beecham Biolog Novel compounds
EP1162999B1 (de) 1999-03-19 2006-11-29 Glaxosmithkline Biologicals S.A. Impstoff gegen Streptococcus pneumoniae
GB0022742D0 (en) 2000-09-15 2000-11-01 Smithkline Beecham Biolog Vaccine
EP2270171B1 (de) * 2000-10-02 2013-09-04 ID Biomedical Corporation of Quebec Haemophilus influenzae-Antigene und entsprechende DNA-Fragmente
RU2185191C1 (ru) * 2001-02-01 2002-07-20 Ростовский научно-исследовательский институт микробиологии и паразитологии Способ получения антигенного препарата haemophilus influenzae типа b (hib)
GB0103171D0 (en) 2001-02-08 2001-03-28 Smithkline Beecham Biolog Vaccine composition
DE20321889U1 (de) 2002-08-02 2012-03-12 Glaxosmithkline Biologicals S.A. Impfstoffzusammensetzung
WO2006110413A2 (en) * 2005-03-30 2006-10-19 Novartis Vaccines And Diagnostics Inc. Haemophilus influenzae type b
CN100357318C (zh) * 2005-10-11 2007-12-26 中山大学 美人鱼发光杆菌外膜蛋白w和编码序列及其制备方法和应用
KR100743604B1 (ko) * 2005-12-05 2007-07-27 볼보 컨스트럭션 이키프먼트 홀딩 스웨덴 에이비 차량용 머플러 구조
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
ES2707499T3 (es) 2005-12-22 2019-04-03 Glaxosmithkline Biologicals Sa Vacuna de conjugado de polisacárido neumocócico
GB0607088D0 (en) 2006-04-07 2006-05-17 Glaxosmithkline Biolog Sa Vaccine
ZA200805602B (en) 2006-01-17 2009-12-30 Arne Forsgren A novel surface exposed haemophilus influenzae protein (protein E; pE)
EA201391788A1 (ru) 2007-06-26 2014-08-29 Глаксосмитклайн Байолоджикалс С.А. Вакцина, содержащая конъюгаты капсульных полисахаридов streptococcus pneumoniae
GB201003922D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Conjugation process
GB201003924D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Immunogenic composition
US9567377B2 (en) 2010-03-10 2017-02-14 Glaxosmithkline Biologicals Sa Immunogenic composition
GB201103836D0 (en) 2011-03-07 2011-04-20 Glaxosmithkline Biolog Sa Conjugation process
EP2717909B1 (de) 2011-06-04 2017-12-06 Rochester General Hospital Research Institute Zusammensetzungen und verfahren in zusammenhang mit p6 von haemophilus influenzae
ES2837825T3 (es) * 2012-04-26 2021-07-01 Glaxosmithkline Biologicals Sa Antígenos y combinaciones de antígenos
CN104370997B (zh) * 2014-09-24 2018-07-31 陈辉 去除生物制品中细菌内毒素的试剂盒、方法及其生物制品的制备方法
GB201518684D0 (en) 2015-10-21 2015-12-02 Glaxosmithkline Biolog Sa Vaccine
GB201621686D0 (en) 2016-12-20 2017-02-01 Glaxosmithkline Biologicals Sa Novel methods for inducing an immune response
GB2600654B (en) 2017-05-30 2022-11-02 Glaxosmithkline Biologicals Sa Novel devices
MX2020005481A (es) 2017-12-01 2020-12-07 Glaxosmithkline Biologicals Sa Purificacion de saponina.
BR112021000965A2 (pt) 2018-08-07 2021-04-27 Glaxosmithkline Biologicals S.A. processos e vacinas
WO2020109365A1 (en) 2018-11-29 2020-06-04 Glaxosmithkline Biologicals Sa Methods for manufacturing an adjuvant
US20220235095A1 (en) 2019-06-05 2022-07-28 Glaxosmithkline Biologicals Sa Saponin purification
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine
GB202205833D0 (en) 2022-04-21 2022-06-08 Glaxosmithkline Biologicals Sa Bacteriophage
WO2024017827A1 (en) 2022-07-19 2024-01-25 Glaxosmithkline Biologicals Sa Continuous process for vaccine production

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990010458A1 (en) * 1989-03-09 1990-09-20 Praxis Biologics, Inc. Vaccines for nontypable haemophilus influenzae
GB8924473D0 (en) * 1989-10-31 1989-12-20 Connaught Lab Outer membrane protein p1 and peptides of haemophilus influenzae b
GB9224584D0 (en) * 1992-11-23 1993-01-13 Connaught Lab Use of outer membrane protein d15 and its peptides as vaccine against haempohilus influenzae diseases

Also Published As

Publication number Publication date
KR19990028423A (ko) 1999-04-15
CA2225405A1 (en) 1997-01-16
US6313281B1 (en) 2001-11-06
AU6236396A (en) 1997-01-30
ES2259443T3 (es) 2006-10-01
JPH11510373A (ja) 1999-09-14
AU708061B2 (en) 1999-07-29
NZ311120A (en) 1999-10-28
TW457247B (en) 2001-10-01
US6254875B1 (en) 2001-07-03
NO976119L (no) 1998-02-26
ATE317013T1 (de) 2006-02-15
EP0835313B1 (de) 2006-02-01
CN1144875C (zh) 2004-04-07
CN1189186A (zh) 1998-07-29
EP0835313A1 (de) 1998-04-15
US6245338B1 (en) 2001-06-12
NO976119D0 (no) 1997-12-29
MX9710412A (es) 1998-07-31
JP2009034107A (ja) 2009-02-19
ZA965482B (en) 1997-12-29
US6284477B1 (en) 2001-09-04
DE69635783T2 (de) 2006-11-02
GB9513074D0 (en) 1995-08-30
WO1997001638A1 (en) 1997-01-16
RU2221045C2 (ru) 2004-01-10

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