[go: up one dir, main page]

DE69630444D1 - Spritze zur lyophilisation, rekonstitution und verabreichung - Google Patents

Spritze zur lyophilisation, rekonstitution und verabreichung

Info

Publication number
DE69630444D1
DE69630444D1 DE69630444T DE69630444T DE69630444D1 DE 69630444 D1 DE69630444 D1 DE 69630444D1 DE 69630444 T DE69630444 T DE 69630444T DE 69630444 T DE69630444 T DE 69630444T DE 69630444 D1 DE69630444 D1 DE 69630444D1
Authority
DE
Germany
Prior art keywords
barrel
syringe
channels
open end
delivery passage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69630444T
Other languages
English (en)
Other versions
DE69630444T2 (de
Inventor
W Grabenkort
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of DE69630444D1 publication Critical patent/DE69630444D1/de
Application granted granted Critical
Publication of DE69630444T2 publication Critical patent/DE69630444T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3103—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
    • A61M2005/3104—Caps for syringes without needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3103—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
    • A61M2005/3106—Plugs for syringes without needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3123—Details having air entrapping or venting means, e.g. purging channels in pistons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3128—Incorporating one-way valves, e.g. pressure-relief or non-return valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
    • A61M2005/31598—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing having multiple telescopically sliding coaxial pistons encompassing volumes for components to be mixed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A61M5/3135—Syringe barrels characterised by constructional features of the proximal end

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Drying Of Solid Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69630444T 1995-03-29 1996-03-27 Spritze zur lyophilisation, rekonstitution und verabreichung Expired - Fee Related DE69630444T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US41262395A 1995-03-29 1995-03-29
US412623 1995-03-29
US08/620,061 US5779668A (en) 1995-03-29 1996-03-21 Syringe barrel for lyophilization, reconstitution and administration
US620061 1996-03-21
PCT/US1996/004144 WO1996030066A1 (en) 1995-03-29 1996-03-27 Syringe barrel for lyophilization, reconstitution and administration

Publications (2)

Publication Number Publication Date
DE69630444D1 true DE69630444D1 (de) 2003-11-27
DE69630444T2 DE69630444T2 (de) 2004-08-12

Family

ID=27021836

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69630444T Expired - Fee Related DE69630444T2 (de) 1995-03-29 1996-03-27 Spritze zur lyophilisation, rekonstitution und verabreichung

Country Status (11)

Country Link
US (1) US5779668A (de)
EP (1) EP0821599B1 (de)
JP (1) JP3803934B2 (de)
AT (1) ATE252400T1 (de)
AU (1) AU712959B2 (de)
CA (1) CA2216926C (de)
DE (1) DE69630444T2 (de)
DK (1) DK0821599T3 (de)
ES (1) ES2210355T3 (de)
PT (1) PT821599E (de)
WO (1) WO1996030066A1 (de)

Families Citing this family (197)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6681810B2 (en) 1994-12-20 2004-01-27 Aradigm Corporation Filling device for a needleless injector cartridge
US5876372A (en) * 1995-03-22 1999-03-02 Abbott Laboratories Syringe system accomodating seperate prefilled barrels for two constituents
WO2000071185A2 (en) * 1999-05-19 2000-11-30 Weston Medical Ltd Needleless injector drug capsule
WO1997036785A1 (en) 1996-04-02 1997-10-09 Weston Medical Limited Method of filling a drug capsule and article produced thereby
JP2001502938A (ja) * 1996-09-27 2001-03-06 アボツト・ラボラトリーズ ２成分の別個の充填済みバレルを含むシリンジシステム
US5782803A (en) * 1996-11-26 1998-07-21 Jentzen; S. William Low dead space, interchangeable needle syringe
JPH11155951A (ja) * 1997-12-01 1999-06-15 Kaken Pharmaceut Co Ltd 減圧シリンジおよびその製造方法
US6135771A (en) * 1997-12-02 2000-10-24 Centrix, Inc. Dental cartridge having an attachable delivery portion
US5931816A (en) * 1998-03-24 1999-08-03 Novinkov; Oleg L. Syringe and method of using same
US6907679B2 (en) * 1998-11-12 2005-06-21 Qlt Usa, Inc. Method for lyophilizing an active agent
US6641565B1 (en) 1998-11-13 2003-11-04 Elan Pharma International Limited drug delivery systems and methods
US6406455B1 (en) * 1998-12-18 2002-06-18 Biovalve Technologies, Inc. Injection devices
GB9905258D0 (en) * 1999-03-09 1999-04-28 Nmt Group Plc Syringe for use with hypodermic needle
US6527738B1 (en) * 1999-04-30 2003-03-04 Prismedical Corporation Drug delivery pack
US8226598B2 (en) * 1999-09-24 2012-07-24 Tolmar Therapeutics, Inc. Coupling syringe system and methods for obtaining a mixed composition
US20020055708A1 (en) * 1999-09-24 2002-05-09 Peterson Kenneth R. Coupling syringe system and methods for obtaining a mixed composition
SE9904539D0 (sv) * 1999-12-10 1999-12-10 Alphahelix Ab Method and device for the handling of samples and reagents
CA2395902A1 (en) * 1999-12-28 2001-07-05 Asger Lau Dalmose Dual chamber syringe with a dual function piston
US20010037091A1 (en) * 1999-12-29 2001-11-01 Wironen John F. System for reconstituting pastes and methods of using same
ATE297769T1 (de) * 2000-02-23 2005-07-15 Hospira Inc Spritzen und spritzensysteme zur selektiven verabreichung von kontrollierten mengen einer therapeutischen substanz
US6566144B1 (en) 2000-03-27 2003-05-20 Atrix Laboratories Cover plate for use in lyophilization
US6626870B1 (en) * 2000-03-27 2003-09-30 Artix Laboratories, Inc. Stoppering method to maintain sterility
US6440101B1 (en) * 2000-05-31 2002-08-27 Abbott Laboratories Syringe systems for lyophilized drugs and methods for making the same
US6936031B2 (en) 2000-12-12 2005-08-30 Gambro Dasco S.P.A. Site for access to the inside of a channel, and corresponding cannula
AU2002232104A1 (en) * 2001-02-26 2002-09-12 Ben-Ami Ballin Syringe for use in blood analysis
US20030032935A1 (en) * 2001-08-10 2003-02-13 Scimed Life Systems, Inc. Packages facilitating convenient mixing and delivery of liquids
WO2003028785A2 (en) * 2001-10-03 2003-04-10 Medical Instill Technologies, Inc. Syringe and reconstitution syringe
US7798185B2 (en) * 2005-08-01 2010-09-21 Medical Instill Technologies, Inc. Dispenser and method for storing and dispensing sterile food product
US9226876B2 (en) 2001-10-19 2016-01-05 The Goodyear Tire & Rubber Company Rubber for baby bottle nipples, pacifiers, and syringe plungers
US6871751B2 (en) * 2001-10-19 2005-03-29 The Goodyear Tire & Rubber Company Rubber for baby bottle nipples, pacifiers, & syringe plungers
US7094369B2 (en) 2002-03-29 2006-08-22 Scimed Life Systems, Inc. Processes for manufacturing polymeric microspheres
US7462366B2 (en) 2002-03-29 2008-12-09 Boston Scientific Scimed, Inc. Drug delivery particle
US7131997B2 (en) 2002-03-29 2006-11-07 Scimed Life Systems, Inc. Tissue treatment
US7053134B2 (en) 2002-04-04 2006-05-30 Scimed Life Systems, Inc. Forming a chemically cross-linked particle of a desired shape and diameter
CA2492339A1 (en) 2002-06-12 2003-12-24 Boston Scientific Limited Bulking agents
US7449236B2 (en) 2002-08-09 2008-11-11 Boston Scientific Scimed, Inc. Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
US7842377B2 (en) 2003-08-08 2010-11-30 Boston Scientific Scimed, Inc. Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
US8012454B2 (en) 2002-08-30 2011-09-06 Boston Scientific Scimed, Inc. Embolization
US7135027B2 (en) * 2002-10-04 2006-11-14 Baxter International, Inc. Devices and methods for mixing and extruding medically useful compositions
US7588825B2 (en) 2002-10-23 2009-09-15 Boston Scientific Scimed, Inc. Embolic compositions
US7883490B2 (en) 2002-10-23 2011-02-08 Boston Scientific Scimed, Inc. Mixing and delivery of therapeutic compositions
EP1631496B1 (de) 2003-04-28 2014-02-26 Medical Instill Technologies, Inc. Behälter mit ventilanordnung zum füllen und abgeben von stoffen und vorrichtung und verfahren zum füllen
US20050027255A1 (en) * 2003-07-31 2005-02-03 Sid Technologies, Llc Automatic injector
TWM246502U (en) * 2003-08-19 2004-10-11 Lite On It Corp A sealing design of a piston
US7976823B2 (en) 2003-08-29 2011-07-12 Boston Scientific Scimed, Inc. Ferromagnetic particles and methods
JP2007526023A (ja) * 2003-10-24 2007-09-13 エム ディー シー インベストメント ホールディングス インコーポレイテッド デュアルチャンバー混合シリンジおよびその使用方法
US7901770B2 (en) 2003-11-04 2011-03-08 Boston Scientific Scimed, Inc. Embolic compositions
US7736671B2 (en) 2004-03-02 2010-06-15 Boston Scientific Scimed, Inc. Embolization
US8173176B2 (en) 2004-03-30 2012-05-08 Boston Scientific Scimed, Inc. Embolization
US7677419B2 (en) * 2004-04-21 2010-03-16 Nordson Corporation Syringes and methods of syringe manufacturing
US7101354B2 (en) 2004-05-03 2006-09-05 Infusive Technologies, Llc Mixing syringe with and without flush
US7998106B2 (en) 2004-05-03 2011-08-16 Thorne Jr Gale H Safety dispensing system for hazardous substances
GB2414775B (en) * 2004-05-28 2008-05-21 Cilag Ag Int Releasable coupling and injection device
GB2414409B (en) * 2004-05-28 2009-11-18 Cilag Ag Int Injection device
GB2414400B (en) 2004-05-28 2009-01-14 Cilag Ag Int Injection device
PL1755712T3 (pl) 2004-05-28 2018-06-29 Cilag Gmbh International Urządzenie do iniekcji
GB2414406B (en) * 2004-05-28 2009-03-18 Cilag Ag Int Injection device
GB2414403B (en) 2004-05-28 2009-01-07 Cilag Ag Int Injection device
GB2414401B (en) 2004-05-28 2009-06-17 Cilag Ag Int Injection device
GB2414399B (en) 2004-05-28 2008-12-31 Cilag Ag Int Injection device
GB2414402B (en) 2004-05-28 2009-04-22 Cilag Ag Int Injection device
GB2414405B (en) * 2004-05-28 2009-01-14 Cilag Ag Int Injection device
US7311861B2 (en) 2004-06-01 2007-12-25 Boston Scientific Scimed, Inc. Embolization
US7294119B2 (en) * 2004-06-10 2007-11-13 Safety Syringes, Inc. Passive delivery system diluents mixing and delivery
AU2005285279B2 (en) 2004-09-10 2012-03-22 Becton, Dickinson And Company Reconstituting infusion device
US7766018B2 (en) * 2004-09-30 2010-08-03 Smoke-Break, Inc. Device and composition for reducing the incidence of tobacco smoking
AT500930B1 (de) 2004-10-25 2007-03-15 Pharma Consult Ges M B H & Co Verfahren und vorrichtung zum lyophilisieren, rekonstituieren und verabreichen eines rekonstituierten wirkstoffes
US8425550B2 (en) 2004-12-01 2013-04-23 Boston Scientific Scimed, Inc. Embolic coils
CA2587950C (en) 2004-12-01 2014-02-11 Wlt Distributors Inc. Needle-free injector
WO2006066336A1 (en) * 2004-12-24 2006-06-29 Moore, Ian, Marshall Safety syringe
US20060144869A1 (en) * 2004-12-30 2006-07-06 Chang Byeong S Container closure delivery system
US20060157507A1 (en) * 2004-12-30 2006-07-20 Chang Byeong S Multi-functional container closure delivery system
US7959600B2 (en) 2004-12-30 2011-06-14 Byeong S. Chang Container closure delivery system
US7858183B2 (en) 2005-03-02 2010-12-28 Boston Scientific Scimed, Inc. Particles
US7727555B2 (en) 2005-03-02 2010-06-01 Boston Scientific Scimed, Inc. Particles
GB2425062B (en) 2005-04-06 2010-07-21 Cilag Ag Int Injection device
GB2424838B (en) 2005-04-06 2011-02-23 Cilag Ag Int Injection device (adaptable drive)
GB2424836B (en) 2005-04-06 2010-09-22 Cilag Ag Int Injection device (bayonet cap removal)
GB2427826B (en) 2005-04-06 2010-08-25 Cilag Ag Int Injection device comprising a locking mechanism associated with integrally formed biasing means
GB2424835B (en) 2005-04-06 2010-06-09 Cilag Ag Int Injection device (modified trigger)
US7963287B2 (en) 2005-04-28 2011-06-21 Boston Scientific Scimed, Inc. Tissue-treatment methods
US9463426B2 (en) 2005-06-24 2016-10-11 Boston Scientific Scimed, Inc. Methods and systems for coating particles
DE102005038495A1 (de) * 2005-08-13 2007-02-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Doppelkammer-Behälter und Verfahren zu dessen Befüllung
DE102005038458A1 (de) * 2005-08-13 2007-02-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Doppelkammer-Behälter ohne Bypass im zylindrischen Körper
DE102005038368A1 (de) * 2005-08-13 2007-02-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Doppelkammer-Behälter zur Lyophilisation, Verfahren zu dessen Befüllung und dessen Verwendung
DE102005038497A1 (de) * 2005-08-13 2007-02-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Doppelkammer-Behälter ohne Bypass
EP1759729B1 (de) 2005-08-30 2009-12-23 Cilag GmbH International Nadelvorrichtung für eine vorgefüllte Spritze
FR2890316B1 (fr) * 2005-09-02 2007-10-05 Aguettant Soc Par Actions Simp Seringue destinee a etre remplie puis sterilisee par autoclavage a la vapeur.
US20110098656A1 (en) 2005-09-27 2011-04-28 Burnell Rosie L Auto-injection device with needle protecting cap having outer and inner sleeves
US8007509B2 (en) 2005-10-12 2011-08-30 Boston Scientific Scimed, Inc. Coil assemblies, components and methods
WO2007048016A2 (en) * 2005-10-20 2007-04-26 Synthes (U.S.A.) Perfusion device and method
US8152839B2 (en) 2005-12-19 2012-04-10 Boston Scientific Scimed, Inc. Embolic coils
US8101197B2 (en) 2005-12-19 2012-01-24 Stryker Corporation Forming coils
US7947368B2 (en) 2005-12-21 2011-05-24 Boston Scientific Scimed, Inc. Block copolymer particles
US7501179B2 (en) 2005-12-21 2009-03-10 Boston Scientific Scimed, Inc. Block copolymer particles
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
CN101394880A (zh) * 2006-02-28 2009-03-25 久光制药株式会社 注射筒
US7966746B2 (en) * 2006-04-24 2011-06-28 Medical Instill Technologies, LLC Needle penetrable and laser resealable lyophilization method
US7776010B2 (en) * 2006-05-01 2010-08-17 Ultradent Products, Inc. Syringe-in-syringe hollow inner barrel/plunger with integral seal and rupturable membrane and related kits, systems, and methods
EP2049062B1 (de) 2006-05-25 2013-06-26 Bayer HealthCare, LLC Rekonstitutionsvorrichtung
GB2438590B (en) 2006-06-01 2011-02-09 Cilag Gmbh Int Injection device
GB2438593B (en) 2006-06-01 2011-03-30 Cilag Gmbh Int Injection device (cap removal feature)
GB2438591B (en) 2006-06-01 2011-07-13 Cilag Gmbh Int Injection device
JP2009543902A (ja) 2006-07-10 2009-12-10 メディパックス インコーポレイテッド 超弾性エポキシヒドロゲル
US8517226B2 (en) * 2006-08-09 2013-08-27 Medmix Systems Ag Syringe with a piston
MX2009002455A (es) * 2006-09-07 2009-03-20 Wyeth Corp Sistemas de mezclado de cemento para huesos y metodos relacionados.
US8540683B2 (en) * 2006-10-09 2013-09-24 Acist Medical Systems, Inc. Syringe device and injector system including a vent for relieving a vacuum within a syringe
US8414927B2 (en) 2006-11-03 2013-04-09 Boston Scientific Scimed, Inc. Cross-linked polymer particles
US8382704B2 (en) 2006-12-29 2013-02-26 Medrad, Inc. Systems and methods of delivering a dilated slurry to a patient
JP4628373B2 (ja) * 2007-01-10 2011-02-09 西川商事株式会社 注射器
US8454558B2 (en) 2007-02-09 2013-06-04 Ultradent Products, Inc. Syringe-in-syringe hollow inner barrel/plunger with integral seal and rupturable membrane and related kits, systems and methods
CN101677907A (zh) * 2007-04-10 2010-03-24 桑多斯股份公司 用于药剂的口服的装置
US9044378B2 (en) 2007-05-31 2015-06-02 Safety Syringes, Inc. Anti-needle stick safety device or system for use with drugs requiring reconstitution
US8231568B2 (en) 2007-10-16 2012-07-31 Nordson Corporation Syringes with a reduced susceptibility to freeze-thaw void formation and methods of manufacturing such syringes
US9995295B2 (en) 2007-12-03 2018-06-12 Medipacs, Inc. Fluid metering device
US8383163B2 (en) * 2008-01-29 2013-02-26 Ultradent Products, Inc. Fluoride varnish compositions including an organo phosphoric acid adhesion promoting agent
US8105292B2 (en) * 2008-02-11 2012-01-31 Safety Syringes, Inc. Reconstitution means for safety device
ATE528068T1 (de) * 2008-02-28 2011-10-15 Medmix Systems Ag Einzelkammervorrichtung zur aufnahme und ausgabe von komponenten
GB2461086B (en) 2008-06-19 2012-12-05 Cilag Gmbh Int Injection device
GB2461087B (en) 2008-06-19 2012-09-26 Cilag Gmbh Int Injection device
GB2461084B (en) 2008-06-19 2012-09-26 Cilag Gmbh Int Fluid transfer assembly
GB2461085B (en) 2008-06-19 2012-08-29 Cilag Gmbh Int Injection device
GB2461089B (en) 2008-06-19 2012-09-19 Cilag Gmbh Int Injection device
KR101645050B1 (ko) * 2008-09-09 2016-08-02 백스터 인터내셔널 인코포레이티드 주입 라인의 프라이밍 표시 장치
US8613730B2 (en) 2008-11-26 2013-12-24 Acist Medical Systems, Inc. Apparatus and methods for fluid pressurizing units of injection systems
US20100249753A1 (en) * 2009-02-25 2010-09-30 Gaisser David M Vented syringe system and method for the containment, mixing and ejection of wetted particulate material
EP2405961A4 (de) 2009-03-09 2012-08-08 Purdue Research Foundation Kompakte vorrichtung für schnelle mischung und verabreichung von stoffen an einen patient
ITAR20090017A1 (it) * 2009-03-23 2010-09-24 Nedo Magrini Siringa, particolarmente per uso medico e veterinario, multicamera, monouso e precaricata
WO2011032011A1 (en) 2009-09-10 2011-03-17 Medipacs, Inc. Low profile actuator and improved method of caregiver controlled administration of therapeutics
US7927563B1 (en) * 2009-10-13 2011-04-19 Cytomedix, Inc. Kit for separation of biological fluids
US9500186B2 (en) 2010-02-01 2016-11-22 Medipacs, Inc. High surface area polymer actuator with gas mitigating components
US8973749B2 (en) 2010-06-29 2015-03-10 Biolyph, L.L.C. Reagent preparation assembly
CN103153367A (zh) * 2010-08-13 2013-06-12 赛诺菲-安万特德国有限公司 用于药物输送装置贮液器的连接器
US8734420B2 (en) 2010-08-25 2014-05-27 Baxter International Inc. Packaging assembly to prevent premature activation
KR102253635B1 (ko) 2010-08-25 2021-05-20 박스앨타 게엠베하 사용자 재구성을 용이하게 하는 어셈블리
CN103327939B (zh) 2010-10-15 2017-05-24 科尼尔赛德生物医学公司 用于进入眼睛的装置
US8292846B2 (en) * 2010-10-28 2012-10-23 Tyco Healthcare Group Lp Applicator tip
WO2012061556A1 (en) 2010-11-03 2012-05-10 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism
WO2012067619A1 (en) 2010-11-18 2012-05-24 Biolyph, Llc Reagent preparation and dispensing device
AU2012205676B2 (en) 2011-01-10 2015-05-28 Byeong Seon Chang Compact medication reconstitution device and method
WO2012110057A1 (en) 2011-02-15 2012-08-23 Chemisches Institut Schaefer Ag Cefuroxime safety kit
DE102011013792A1 (de) * 2011-03-03 2012-09-06 Vetter Pharma-Fertigung GmbH & Co. KG Verschluss für eine Pulverspritze und Pulverspritze
US8992505B2 (en) 2011-04-18 2015-03-31 Thorne Consulting & Intellectual Property, LLC Medical syringe filling and valving
US10434292B2 (en) 2011-06-24 2019-10-08 Access Closure Method and devices for flow occlusion during device exchanges
WO2013043861A2 (en) * 2011-09-20 2013-03-28 Glucago Llc D/B/A Lyogo Reconstitution device
EP2847249A4 (de) 2012-03-14 2016-12-28 Medipacs Inc Intelligente polymermaterialien mit überschüssigen reaktiven molekülen
US8992469B2 (en) 2012-06-26 2015-03-31 Glucago Llc Reconstitution device
JP6391082B2 (ja) * 2012-07-31 2018-09-19 株式会社吉野工業所 混合噴出器
EP2879646A1 (de) * 2012-08-06 2015-06-10 Neomed, Inc. System und verfahren für dosierte enterale ernährung
ES3023054T3 (en) 2012-11-08 2025-05-29 Clearside Biomedical Inc Methods for the treatment of ocular disease in human subjects
US9125995B2 (en) 2012-12-05 2015-09-08 Glucago Llc Reconstitution devices
MX372859B (es) 2013-05-03 2020-07-07 Clearside Biomedical Inc Aparatos y métodos para inyección ocular.
EP3003454B1 (de) * 2013-06-03 2020-01-08 Clearside Biomedical, Inc. Vorrichtung zur wirkstofffreisetzung mit mehreren reservoirs
GB2515032A (en) 2013-06-11 2014-12-17 Cilag Gmbh Int Guide for an injection device
GB2515038A (en) 2013-06-11 2014-12-17 Cilag Gmbh Int Injection device
GB2517896B (en) 2013-06-11 2015-07-08 Cilag Gmbh Int Injection device
GB2515039B (en) 2013-06-11 2015-05-27 Cilag Gmbh Int Injection Device
CA2912357C (en) * 2013-06-21 2019-12-31 Ferrosan Medical Devices A/S Vacuum expanded dry composition and syringe for retaining same
IL312865B2 (en) 2013-09-11 2025-06-01 Eagle Biologics Inc Liquid protein formulations containing viscosity-lowering agents
RU2710491C2 (ru) 2014-06-20 2019-12-26 Клиасайд Байомедикал, Инк. Устройство для инъекции лекарственного средства в глазную ткань и способ инъекции лекарственного средства в глазную ткань
MX388547B (es) 2014-09-09 2025-03-20 Byeong Seon Chang Dispositivo y método de entrega de solución.
MX391067B (es) 2014-10-01 2025-03-21 Eagle Biologics Inc Formulaciones de polisacáridos y ácido nucleico que contienen agentes de reducción de viscosidad.
US10653837B2 (en) 2014-12-24 2020-05-19 Ferrosan Medical Devices A/S Syringe for retaining and mixing first and second substances
US9833572B2 (en) 2015-01-19 2017-12-05 Michael E. Berend Modular dual chamber syringe system
USD831204S1 (en) 2015-03-02 2018-10-16 Neomed, Inc. Enteral syringe
USD831203S1 (en) 2015-03-02 2018-10-16 Neomed, Inc. Enteral syringe
USD807502S1 (en) 2015-03-02 2018-01-09 Neomed, Inc. Enteral syringe
US10143625B2 (en) 2015-03-17 2018-12-04 Recon Therapeutics, Inc. Pharmaceutical reconstitution
US10624817B2 (en) 2015-03-24 2020-04-21 Neomed, Inc. Oral administration coupler for back-of-mouth delivery
WO2017005590A1 (en) 2015-07-03 2017-01-12 Ferrosan Medical Devices A/S Syringe for mixing two components and for retaining a vacuum in a storage condition
US10682287B2 (en) 2015-07-14 2020-06-16 Neomed, Inc. Dosing control coupling for enteral fluid transfer and enteral couplings and syringes
JP6694501B2 (ja) 2015-07-14 2020-05-13 ネオメッド, インクNeomed, Inc. 腸内液体流動用の投薬量制御継手
CN108025136B (zh) * 2015-09-11 2020-10-23 西医药服务有限公司 具有凹槽的医疗施用筒和密封其的方法
GEP20217312B (en) 2016-02-05 2021-11-10 Tolmar International Ltd Vented cover plate for an array of syringes
EP3413851B1 (de) 2016-02-10 2023-09-27 Clearside Biomedical, Inc. Verpackung
WO2017147192A1 (en) 2016-02-25 2017-08-31 Neomed, Inc. Syringe plunger with hinged flange
CA3062845A1 (en) 2016-05-02 2017-11-09 Clearside Biomedical, Inc. Systems and methods for ocular drug delivery
IL305537B2 (en) 2016-08-12 2025-02-01 Clearside Biomedical Inc Devices and methods for adjusting the insertion depth of a needle for administering a drug
GB2556088A (en) * 2016-11-18 2018-05-23 Owen Mumford Ltd Packaging and devices for mixing medicament substances
WO2018129443A1 (en) * 2017-01-09 2018-07-12 Cook Biotech Incorporated Lyophilizer container and method of use thereof
EP3248632A1 (de) * 2017-03-17 2017-11-29 Citros VOF Vorrichtung zur aufbewahrung und rekonstitution einer substanz zur verabreichung an eine person
WO2018204515A1 (en) 2017-05-02 2018-11-08 Georgia Tech Research Corporation Targeted drug delivery methods using a microneedle
EP3655054B1 (de) * 2017-07-17 2023-11-08 Boston Scientific Scimed Inc. Kryotherapeutisches abgabevorrichtung
US11040144B1 (en) * 2017-09-13 2021-06-22 Shao Ma Plunger assembly for a syringe apparatus
US11033678B2 (en) 2017-11-20 2021-06-15 Agist Medical Systems, Inc. Compact injector drive
US11040147B2 (en) 2017-11-21 2021-06-22 Acist Medical Systems, Inc. Injector position sensing
CN112368028A (zh) 2018-05-09 2021-02-12 弗罗桑医疗设备公司 用于制备止血组合物的方法
US11654240B2 (en) * 2018-06-01 2023-05-23 Becton, Dickinson And Company Low dose syringe including an air venting system
USD908916S1 (en) 2018-06-19 2021-01-26 Tolmar Therapeutics, Inc. Syringe restrictor plate
EP3911377A1 (de) * 2019-01-16 2021-11-24 Boston Scientific Scimed Inc. Kryotherapeutische abgabevorrichtung
JP7217003B2 (ja) * 2019-02-08 2023-02-02 ナミックス株式会社 樹脂組成物充填済みシリンジ及びその保存方法
FR3093088A1 (fr) 2019-02-21 2020-08-28 Lyofal Contenant pour le conditionnement de matières sous atmosphère contrôlée et procédé de conditionnement utilisant un tel contenant
AU2020325205B2 (en) * 2019-08-06 2023-11-02 Microvention, Inc. Syringe
CN110538363B (zh) * 2019-09-27 2024-06-14 四川大学华西医院 一种稀释后即注型抢救注射器
CN114712618A (zh) * 2021-01-04 2022-07-08 中国人民解放军军事科学院军事医学研究院 一种双室注射器以及一种装料方法
WO2023095094A1 (en) * 2021-11-29 2023-06-01 University Of Miami Ocular drug transfer and dispensing device
WO2025181800A1 (en) * 2024-02-29 2025-09-04 Dali Medical Devices Ltd Dual chamber container and methods of use thereof

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2475939A (en) * 1946-07-12 1949-07-12 Applezweig Norman Cartridge syringe
US3489147A (en) * 1964-07-21 1970-01-13 Joseph Denman Shaw Combination mixing and injecting medical syringe
US3477432A (en) * 1964-07-21 1969-11-11 Joseph Denman Shaw Combination mixing and injecting medical syringe
US3255752A (en) * 1965-01-28 1966-06-14 Dick Peter Hypodermic syringe
DE1766222B1 (de) * 1968-04-20 1970-12-17 Theo Metten Spritze zum Injizieren einer Loesung aus einer Trockensubstanz und einem Loesungsmittel
BE757195A (fr) * 1969-10-07 1971-03-16 Century Disposable Devices Seringue servant a injecter un melange fraichement prepare de poudre etde liquide
US3678931A (en) * 1970-06-09 1972-07-25 Milton J Cohen Syringe
US3838689A (en) * 1970-11-04 1974-10-01 M Cohen Disposable syringe with slit valve
US3757779A (en) * 1971-05-24 1973-09-11 Century Labor Inc Filter syringe
DE7128705U (de) * 1971-07-26 1971-10-28 Hampel H Steril verpackter spritzenzylinder einer einweg-injektionsspritze mit vom kolben loesbarer kolbenstange
US4153057A (en) * 1975-07-24 1979-05-08 Merck Patent Gesellschaft Mit Beschrankter Haftung Stopper for two-chamber mixing syringe
US4171698A (en) * 1977-08-15 1979-10-23 Abbott Laboratories Prefilled two-compartment syringe
US4172457A (en) * 1977-10-06 1979-10-30 American Hospital Supply Corporation Plural component mixing system and method
US4185628A (en) * 1978-05-31 1980-01-29 Kopfer Rudolph J Compartmental syringe
US4581016A (en) * 1984-02-29 1986-04-08 Gettig Pharmaceutical Instrument Co. Dual cartridge wet/dry syringe
US5088996A (en) * 1984-04-16 1992-02-18 Kopfer Rudolph J Anti-aerosoling drug reconstitution device
US4886495A (en) * 1987-07-08 1989-12-12 Duoject Medical Systems Inc. Vial-based prefilled syringe system for one or two component medicaments
GB2203047B (en) * 1987-02-27 1991-01-30 Gilbert Henry Banks Single-use syringe
DE3816961A1 (de) * 1987-07-21 1989-02-02 Wasserburger Arzneimittelwerk Injektionsspritze fuer medizinische zwecke
US4957637A (en) * 1988-05-23 1990-09-18 Sherwood Medical Company Serum separator system for centrifuge with piercable membrane
FR2641191B2 (fr) * 1988-06-03 1991-03-15 Clotteau Jean Seringue a injection unique
US4936315A (en) * 1988-10-20 1990-06-26 Lineback Paul I Methods and apparatus for obtaining arterial blood samples
US5407431A (en) * 1989-07-11 1995-04-18 Med-Design Inc. Intravenous catheter insertion device with retractable needle
US5135507A (en) * 1990-05-10 1992-08-04 Habley Medical Technology Corporation One-piece syringe
CA2016870C (en) * 1990-05-15 1994-03-29 Arnie Drudik Dispenser for storing and mixing several components
US5114405A (en) * 1990-05-21 1992-05-19 Winter Douglas A Single use tamper resistant syringe
DK174390D0 (da) * 1990-07-20 1990-07-20 Novo Nordisk As Tokammersproejte
US5067948A (en) * 1990-09-27 1991-11-26 Habley Medical Technology Corporation Safety, packaging, injection and disposal system for pre-filled pharmaceutical vials
DK288590D0 (da) * 1990-12-04 1990-12-04 Michael Morris Blandings/oploesnings-sproejte til cytostatika for medicinsk behandling af cancer patienter
US5158546A (en) * 1991-08-07 1992-10-27 Habley Medical Technology Corp. Controlled action self-mixing vial
US5289858A (en) * 1991-12-18 1994-03-01 Abbott Laboratories System for accommodating withdrawal of liquid from a bulk supply
US5496288A (en) * 1992-09-23 1996-03-05 Becton, Dickinson And Company Protective cap for hypodermic syringe
JP3172005B2 (ja) * 1992-11-27 2001-06-04 株式会社大協精工 注射器兼容器
EP0695555B1 (de) * 1992-12-01 2001-06-20 HIGASHIKAWA, Tetsuro Spritze
US5370621A (en) * 1992-12-14 1994-12-06 Mallinckrodt Medical, Inc. Insert device for facilitating limited aspiration of a delivery apparatus
US5298024A (en) * 1992-12-28 1994-03-29 Frank Richmond Multi-liquid medicament delivery system with reflex valves
US5520657A (en) * 1993-08-09 1996-05-28 Sellers; Jackie Method and device for vessel location cannulation utilizing a unique needle and syringe device
US5372586A (en) * 1993-10-20 1994-12-13 Habley Medical Technology Corp. Telescoping pharmaceutical storage and mixing syringe
US5569193A (en) * 1995-03-22 1996-10-29 Abbott Laboratories Syringe system accommodating separately storable prefilled containers for two constituents

Also Published As

Publication number Publication date
JPH11504536A (ja) 1999-04-27
AU5373796A (en) 1996-10-16
WO1996030066A1 (en) 1996-10-03
DE69630444T2 (de) 2004-08-12
US5779668A (en) 1998-07-14
PT821599E (pt) 2004-03-31
CA2216926C (en) 2007-04-24
EP0821599A1 (de) 1998-02-04
ES2210355T3 (es) 2004-07-01
EP0821599B1 (de) 2003-10-22
JP3803934B2 (ja) 2006-08-02
DK0821599T3 (da) 2004-03-01
CA2216926A1 (en) 1996-10-03
ATE252400T1 (de) 2003-11-15
AU712959B2 (en) 1999-11-18

Similar Documents

Publication Publication Date Title
DE69630444D1 (de) Spritze zur lyophilisation, rekonstitution und verabreichung
US3924617A (en) Aspiration and infusion needle
US4994043A (en) Two compartment syringe
AR020991A2 (es) Vial de implante, y disposicion de insercion de implante
DE69702973D1 (de) Verfahren zum füllen einer medizinkapsel und dabei erzeugter gegenstand
US5702019A (en) Vial having resealable membrane assembly activated by a medical delivery device
CA1329569C (en) Closure and port assembly
DK134391D0 (da) Applikator til administrering af en veterinaerfarmakologisk sammensaetning
EP0161797A3 (de) Einrichtung zur Wiederaufbereitung eines Heilmittels ohne Aerosolbildung
AU6490701A (en) Syringe systems for lyophilized drugs and methods for making the same
US20030192791A1 (en) Closure device for a medical container
DE59510531D1 (de) Behältnis zur Lagerung und Verabreichung von Injektions-, Infusions- und Diagnostikpräparaten
FI970568A0 (fi) Säiliö ja sulkukansi sekä menetelmä säiliöiden kaasukuplatonta täyttämistä varten
ES8102041A1 (es) Un dispositivo de cierre de frasco de dosis unitaria para administracion oral de medicamento
ATE179881T1 (de) Einen einwegteil eines stiftartigen injektors bildender behälter für eine gefriergetrocknete verbindung sowie anwendungsverfahren
KR970701079A (ko) 물체를 피하 침적시키기 위한 캐뉼라(Cannula for the subcutaneous deposition of an object)
SE7602832L (sv) Sett och anordning for steril overforing av material
JP2018500097A (ja) 流体薬剤成分を混合及び分注するための容器
KR20170101282A (ko) 2가지 성분을 혼합 및 분배하기 위한 용기
GB8725833D0 (en) Ports for fluid containers
US6003702A (en) Vial with resealable connector assembly having a membrane and a multi-configuration fluid access device
ES538969A0 (es) Tapon farmaceutico, piston o similar y procedimiento para su obtencion.
KR930009585A (ko) 약제용기
IT213756Z2 (it) Cappuccio di sigillo particolarmente per flaconi di antibiotici e di infusione e trasfusione.
SE9601540D0 (sv) Improved medical containers

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee