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DE69628194D1 - Verfahren zum nachweis von verbindungen die bestimmte zielmoleküle binden - Google Patents

Verfahren zum nachweis von verbindungen die bestimmte zielmoleküle binden

Info

Publication number
DE69628194D1
DE69628194D1 DE69628194T DE69628194T DE69628194D1 DE 69628194 D1 DE69628194 D1 DE 69628194D1 DE 69628194 T DE69628194 T DE 69628194T DE 69628194 T DE69628194 T DE 69628194T DE 69628194 D1 DE69628194 D1 DE 69628194D1
Authority
DE
Germany
Prior art keywords
target molecules
specific target
target
binding specific
compounds binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69628194T
Other languages
English (en)
Other versions
DE69628194T2 (de
Inventor
Howard Benjamin
Mark A Findeis
L Gefter
Gary Musso
R Signer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Praecis Pharmaceuticals Inc
Original Assignee
Praecis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Praecis Pharmaceuticals Inc filed Critical Praecis Pharmaceuticals Inc
Application granted granted Critical
Publication of DE69628194D1 publication Critical patent/DE69628194D1/de
Publication of DE69628194T2 publication Critical patent/DE69628194T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE69628194T 1995-12-18 1996-12-18 Verfahren zum nachweis von verbindungen die bestimmte zielmoleküle binden Expired - Fee Related DE69628194T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57378695A 1995-12-18 1995-12-18
US573786 1995-12-18
PCT/US1996/020561 WO1997022617A1 (en) 1995-12-18 1996-12-18 Methods for identifying compounds that bind to a target

Publications (2)

Publication Number Publication Date
DE69628194D1 true DE69628194D1 (de) 2003-06-18
DE69628194T2 DE69628194T2 (de) 2004-04-01

Family

ID=24293389

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69628194T Expired - Fee Related DE69628194T2 (de) 1995-12-18 1996-12-18 Verfahren zum nachweis von verbindungen die bestimmte zielmoleküle binden

Country Status (11)

Country Link
US (4) US20030100007A1 (de)
EP (2) EP0868427B1 (de)
JP (1) JP2000502897A (de)
AT (1) ATE240347T1 (de)
AU (1) AU1430297A (de)
CA (1) CA2238995A1 (de)
DE (1) DE69628194T2 (de)
DK (1) DK0868427T3 (de)
ES (1) ES2200084T3 (de)
PT (1) PT868427E (de)
WO (1) WO1997022617A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6326155B1 (en) * 1995-03-20 2001-12-04 Dyax Corp. Engineering affinity ligands for macromolecules
GB9717652D0 (en) * 1997-08-20 1997-10-22 Nycomed Imaging As Method
DE69806066T2 (de) 1997-11-07 2003-02-06 Conjuchem, Inc. Affinitätsmarkierer für menschliches serum albumin
EP1199566B1 (de) * 1997-11-07 2008-08-27 ConjuChem Biotechnologies Inc. Methoden zum Screening von Affinitätsmarker-Bibliotheken
GB9809776D0 (en) * 1998-05-07 1998-07-08 Nycomed Imaging As Method
GB9809780D0 (en) * 1998-05-07 1998-07-08 Nycomed Imaging As Method
ATE455304T1 (de) 2000-04-14 2010-01-15 Genencor Int Verfahren zur selektiven zielen
US7129326B2 (en) 2000-04-14 2006-10-31 Genencor International, Inc. Methods for selective targeting
JP2004530117A (ja) * 2001-02-22 2004-09-30 プラエシス ファーマシューティカルズ インコーポレーテッド 生物プロセスを調節するペプチドを同定する方法
WO2003029409A2 (en) * 2001-09-28 2003-04-10 Selectx Pharmaceuticals, Inc. Methods for generating, selecting, and identifying compounds which bind a target molecule
EP2581383A1 (de) 2002-11-25 2013-04-17 Genencor International, Inc. Haut- oder haarbindende Peptide
WO2005012909A1 (en) * 2003-03-04 2005-02-10 Auburn University Methods of forming monolayers of phage-derived products and uses thereof
EP1940355B1 (de) 2005-09-30 2012-12-19 Auburn University Nanoträger zur gezielten Freisetzung eines Wirkstoffs - enthaltend Ansammlungen von auf ein Ziel ausgerichteten Landschaftsphagenproteinen
WO2010052244A1 (en) 2008-11-05 2010-05-14 Morphosys Ag Deconvolution method
DK3087083T3 (da) 2013-12-27 2019-12-16 Hoffmann La Roche Systemisk opdagelse, modning og forlængelse af peptidbindere til proteiner
US20180340174A1 (en) 2014-11-11 2018-11-29 Nanocore Aps Method for identification of molecules with desired characteristics
EP3286569B1 (de) 2015-04-20 2020-07-22 H. Hoffnabb-La Roche Ag Mittels systemischer entdeckung, reifung und extension identifizierte spezifische peptidbinder an proteine
KR102497769B1 (ko) * 2016-12-22 2023-02-07 니폰 제온 가부시키가이샤 올리고펩타이드의 탐색 방법, 올리고펩타이드, 수식 펩타이드, 및 면역 측정 방법

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0190205B1 (de) * 1984-07-24 1992-10-21 Coselco Mimotopes Pty. Ltd. Verfahren zur bestimmung von mimotopen
US5266684A (en) * 1988-05-02 1993-11-30 The Reagents Of The University Of California Peptide mixtures
US5223409A (en) * 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
DE768377T1 (de) * 1988-09-02 1998-01-02 Dyax Corp Herstellung und Auswahl von Rekombinantproteinen mit verschiedenen Bindestellen
US5096815A (en) * 1989-01-06 1992-03-17 Protein Engineering Corporation Generation and selection of novel dna-binding proteins and polypeptides
US5198346A (en) * 1989-01-06 1993-03-30 Protein Engineering Corp. Generation and selection of novel DNA-binding proteins and polypeptides
US5366862A (en) * 1990-02-14 1994-11-22 Receptor Laboratories, Inc. Method for generating and screening useful peptides
US5723286A (en) * 1990-06-20 1998-03-03 Affymax Technologies N.V. Peptide library and screening systems
US5650489A (en) * 1990-07-02 1997-07-22 The Arizona Board Of Regents Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
US6197529B1 (en) * 1990-11-21 2001-03-06 Torrey Pines Institute For Molecular Studies Linear substituted oligoalkyleneimine libraries
US5331573A (en) * 1990-12-14 1994-07-19 Balaji Vitukudi N Method of design of compounds that mimic conformational features of selected peptides
US5475085A (en) * 1991-02-07 1995-12-12 Molecumetics, Ltd. Conformationally restricted mimetics of beta turns and beta bulges and peptides containing the same
US5270170A (en) * 1991-10-16 1993-12-14 Affymax Technologies N.V. Peptide library and screening method
US5470753A (en) * 1992-09-03 1995-11-28 Selectide Corporation Peptide sequencing using mass spectrometry
IL106106A0 (en) * 1993-06-22 1993-10-20 Interpharm Lab Ltd Library of polymeric molecules and its preparation
FI962371A0 (fi) * 1993-12-09 1996-06-07 Ciba Geigy Ag Menetelmä kombinatoristen yhdistekirjastojen valmistamiseksi
US5861476A (en) * 1994-02-02 1999-01-19 Affymax Technologies N.V. Peptides and compounds that bind to the IL-1 receptor
CA2185918A1 (en) * 1994-04-05 1995-10-12 Genzyme Corporation Determination and identification of active compounds in a compound library
US6475806B1 (en) * 1995-06-07 2002-11-05 Praecis Pharmaceuticals, Inc. Anchor libraries and identification of peptide binding sequences

Also Published As

Publication number Publication date
DE69628194T2 (de) 2004-04-01
EP0868427B1 (de) 2003-05-14
PT868427E (pt) 2003-09-30
AU1430297A (en) 1997-07-14
US20040091904A1 (en) 2004-05-13
US20010006778A1 (en) 2001-07-05
WO1997022617A1 (en) 1997-06-26
ES2200084T3 (es) 2004-03-01
JP2000502897A (ja) 2000-03-14
EP1283212A1 (de) 2003-02-12
DK0868427T3 (da) 2003-09-15
CA2238995A1 (en) 1997-06-26
US20080032896A1 (en) 2008-02-07
EP0868427A1 (de) 1998-10-07
HK1016194A1 (en) 1999-10-29
ATE240347T1 (de) 2003-05-15
US20030100007A1 (en) 2003-05-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: PRAECIS PHARMACEUTICALS INC., WALTHAM, MASS., US

8339 Ceased/non-payment of the annual fee