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DE69616956T3 - 3-Amino-2-mercaptobenzoesäure-Derivate und Verfahren zu ihrer Herstellung - Google Patents

3-Amino-2-mercaptobenzoesäure-Derivate und Verfahren zu ihrer Herstellung Download PDF

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Publication number
DE69616956T3
DE69616956T3 DE69616956.8T DE69616956T DE69616956T3 DE 69616956 T3 DE69616956 T3 DE 69616956T3 DE 69616956 T DE69616956 T DE 69616956T DE 69616956 T3 DE69616956 T3 DE 69616956T3
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DE
Germany
Prior art keywords
substituted
unsubstituted
formula
compound
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69616956.8T
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German (de)
English (en)
Other versions
DE69616956T2 (de
DE69616956D1 (de
Inventor
Walter Kunz
Beat Jau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syngenta Participations AG
Original Assignee
Syngenta Participations AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
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Application granted granted Critical
Publication of DE69616956D1 publication Critical patent/DE69616956D1/de
Publication of DE69616956T2 publication Critical patent/DE69616956T2/de
Publication of DE69616956T3 publication Critical patent/DE69616956T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01Five-membered rings
    • C07D285/02Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/14Thiadiazoles; Hydrogenated thiadiazoles condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/02Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/02Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols
    • C07C319/12Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols by reactions not involving the formation of mercapto groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/62Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/63Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00Thiocarboxylic acids
    • C07C327/20Esters of monothiocarboxylic acids
    • C07C327/26Esters of monothiocarboxylic acids having carbon atoms of esterified thiocarboxyl groups bound to carbon atoms of six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04Derivatives of thiourea
    • C07C335/16Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C335/22Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/68Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Cephalosporin Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE69616956.8T 1995-12-21 1996-12-12 3-Amino-2-mercaptobenzoesäure-Derivate und Verfahren zu ihrer Herstellung Expired - Lifetime DE69616956T3 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH363795 1995-12-21
CH363795 1995-12-21
EP96810865.4A EP0780372B3 (en) 1995-12-21 1996-12-12 3-Amino-2-mercaptobenzoic acid derivatives and processes for their preparation
US08/770,353 US5770758A (en) 1995-12-21 1996-12-20 3-amino-2-mercaptobenzoic acid derivatives and processes for their preparation

Publications (3)

Publication Number Publication Date
DE69616956D1 DE69616956D1 (de) 2001-12-20
DE69616956T2 DE69616956T2 (de) 2002-06-20
DE69616956T3 true DE69616956T3 (de) 2014-01-30

Family

ID=25693502

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69616956.8T Expired - Lifetime DE69616956T3 (de) 1995-12-21 1996-12-12 3-Amino-2-mercaptobenzoesäure-Derivate und Verfahren zu ihrer Herstellung

Country Status (21)

Country Link
US (1) US5770758A (es)
EP (1) EP0780372B3 (es)
JP (1) JP4217924B2 (es)
KR (1) KR100470887B1 (es)
CN (2) CN1163491C (es)
AT (1) ATE208760T1 (es)
AU (1) AU713526B2 (es)
BR (1) BR9606092A (es)
CA (1) CA2193460C (es)
CZ (1) CZ291857B6 (es)
DE (1) DE69616956T3 (es)
DK (1) DK0780372T3 (es)
ES (1) ES2168121T7 (es)
HU (1) HU221600B (es)
IL (3) IL133900A (es)
MX (2) MX9606665A (es)
PL (1) PL187885B1 (es)
PT (1) PT780372E (es)
RU (1) RU2176241C2 (es)
SK (1) SK283840B6 (es)
ZA (1) ZA9610774B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6002013A (en) * 1995-12-21 1999-12-14 Novartis Corporation 3-amino-2-mercaptobenzoic acid derivatives and processes for their preparation
GB9724586D0 (en) * 1997-11-20 1998-01-21 Rhone Poulenc Agriculture New herbicides
SK288115B6 (sk) 2002-09-25 2013-09-03 Memory Pharmaceuticals Corporation Indazoles, pharmaceutical compositions comprising them and their use
DE10313887A1 (de) * 2003-03-27 2004-10-28 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren zum selektiven Gewinnen von Gold aus goldhaltigen Materialien
ES2528631T3 (es) 2003-04-08 2015-02-11 Progenics Pharmaceuticals, Inc. Formulaciones farmacéuticas que contienen metilnaltrexona
KR20070007759A (ko) * 2003-07-10 2007-01-16 아칠리온 파르마세우티칼스 인코포레이티드 바이러스 복제 억제제로서 유용한 치환된 아릴티오우레아유도체
MXPA06010852A (es) 2004-03-25 2007-01-16 Memory Pharm Corp Indazoles, benzotiazoles, benzoisotiazoles, bencisoxazoles y preparacion y usos de los mismos.
AR057035A1 (es) 2005-05-25 2007-11-14 Progenics Pharm Inc SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS
AR057325A1 (es) 2005-05-25 2007-11-28 Progenics Pharm Inc Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
CA2644520A1 (en) * 2006-03-02 2007-09-13 Mallinckrodt Inc. Thiadiazole compounds and their use in phototherapy
TWI489984B (zh) 2006-08-04 2015-07-01 Wyeth Corp 用於非經腸道傳輸化合物之配方及其用途
MX2009010550A (es) 2007-03-29 2009-12-14 Progenics Pharm Inc Formas de cristal de bromuro de (r)-n-metilnaltrexona y uso de las mismas.
PA8774201A1 (es) 2007-03-29 2009-06-23 Progenics Pharm Inc Antagonista del receptor
PT2139890E (pt) 2007-03-29 2014-09-03 Wyeth Llc Antagonistas do receptor opióide periférico e respectivas utilizações
CN101959892B (zh) 2008-02-06 2014-01-08 普罗热尼奇制药公司 (r),(r)-2,2’-二-甲基纳曲酮的制备和用途
CA2676881C (en) 2008-09-30 2017-04-25 Wyeth Peripheral opioid receptor antagonists and uses thereof
CN101492429B (zh) * 2008-12-10 2010-12-15 上海泰禾(集团)有限公司 一种苯并-[1,2,3]-噻二唑-7-甲酸三氟乙酯的提纯方法
CN117024373B (zh) * 2023-08-23 2025-07-25 首建科技有限公司 一种2-氨基-4-甲基苯并噻唑的制备工艺

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4150140A (en) * 1976-12-23 1979-04-17 The Upjohn Company Benzothiazolyl oxanic acids, esters and salts
DE2757924A1 (de) * 1977-12-24 1979-07-05 Hoechst Ag Verfahren zur herstellung von vinylchlorid-polymerisaten
DE3601286A1 (de) * 1986-01-17 1987-07-23 Consiglio Nazionale Ricerche Sammelmittel fuer die selektive flotation von blei- und zinkerzen und verfahren zu deren herstellung
ES2052772T3 (es) * 1987-08-21 1994-07-16 Ciba Geigy Ag Procedimiento y agente contra enfermedades de plantas.
DK0384889T3 (da) * 1989-02-21 1993-11-15 Ciba Geigy Ag Middel til beskyttelse af planter mod sygdomme
DE59207481D1 (de) 1991-08-30 1996-12-12 Hoechst Ag Verfahren zur Herstellung von 2-Aminobenzthiazolen
JPH0690518A (ja) * 1992-09-09 1994-03-29 Toshiba Corp 地絡継電器
JP3310104B2 (ja) * 1994-04-04 2002-07-29 三新化学工業株式会社 2−アミノチオフェノール類の製造方法
PL319692A1 (en) * 1994-10-17 1997-08-18 Ciba Geigy Ag Method of obtaining substituted 3-amino benzonitriles

Also Published As

Publication number Publication date
EP0780372B3 (en) 2013-05-22
MX9606665A (es) 1997-06-28
US5770758A (en) 1998-06-23
CZ291857B6 (cs) 2003-06-18
PL317601A1 (en) 1997-06-23
HUP9603527A2 (en) 1997-09-29
ES2168121T3 (es) 2002-06-01
CN1156722A (zh) 1997-08-13
CZ377396A3 (en) 1997-07-16
ES2168121T7 (es) 2013-09-24
JPH09235279A (ja) 1997-09-09
PL187885B1 (pl) 2004-10-29
IL133900A (en) 2004-07-25
HUP9603527A3 (en) 1999-04-28
CN1078888C (zh) 2002-02-06
JP4217924B2 (ja) 2009-02-04
EP0780372B1 (en) 2001-11-14
SK163696A3 (en) 1997-10-08
EP0780372A3 (en) 1997-09-17
AU713526B2 (en) 1999-12-02
ATE208760T1 (de) 2001-11-15
HU221600B (hu) 2002-11-28
IL119819A (en) 2004-07-25
DE69616956T2 (de) 2002-06-20
CN1392144A (zh) 2003-01-22
MXPA02000515A (es) 2002-09-17
DK0780372T3 (da) 2002-03-11
EP0780372A2 (en) 1997-06-25
DE69616956D1 (de) 2001-12-20
RU2176241C2 (ru) 2001-11-27
SK283840B6 (sk) 2004-03-02
BR9606092A (pt) 1998-09-01
CA2193460C (en) 2007-03-27
HU9603527D0 (en) 1997-02-28
CN1163491C (zh) 2004-08-25
CA2193460A1 (en) 1997-06-22
AU7640496A (en) 1997-06-26
KR100470887B1 (ko) 2005-03-14
AU713526C (en) 1997-06-26
PT780372E (pt) 2002-04-29
IL119819A0 (en) 1997-03-18
IL133900A0 (en) 2001-04-30
ZA9610774B (en) 1997-06-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN

8328 Change in the person/name/address of the agent

Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC