DE69535704D1 - EXPRESSIONSPLASMIDE, DURCH EINEN osmB PROMOTER REGULIERT - Google Patents
EXPRESSIONSPLASMIDE, DURCH EINEN osmB PROMOTER REGULIERTInfo
- Publication number
- DE69535704D1 DE69535704D1 DE69535704T DE69535704T DE69535704D1 DE 69535704 D1 DE69535704 D1 DE 69535704D1 DE 69535704 T DE69535704 T DE 69535704T DE 69535704 T DE69535704 T DE 69535704T DE 69535704 D1 DE69535704 D1 DE 69535704D1
- Authority
- DE
- Germany
- Prior art keywords
- regulated
- osmb promoter
- plasmids
- expression
- plasmide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 101150004298 osmB gene Proteins 0.000 title abstract 2
- 230000001105 regulatory effect Effects 0.000 title 1
- 239000013612 plasmid Substances 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 102000012440 Acetylcholinesterase Human genes 0.000 abstract 1
- 108010022752 Acetylcholinesterase Proteins 0.000 abstract 1
- 102000019197 Superoxide Dismutase Human genes 0.000 abstract 1
- 108010012715 Superoxide dismutase Proteins 0.000 abstract 1
- 229940022698 acetylcholinesterase Drugs 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 239000000122 growth hormone Substances 0.000 abstract 1
- 208000006454 hepatitis Diseases 0.000 abstract 1
- 231100000283 hepatitis Toxicity 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0089—Oxidoreductases (1.) acting on superoxide as acceptor (1.15)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US216851 | 1994-03-22 | ||
| US08/216,851 US5795776A (en) | 1994-03-22 | 1994-03-22 | Expression plasmids regulated by an OSMB promoter |
| PCT/US1995/003622 WO1995025785A1 (en) | 1994-03-22 | 1995-03-22 | EXPRESSION PLASMIDS REGULATED BY AN osmB PROMOTER |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69535704D1 true DE69535704D1 (de) | 2008-03-27 |
| DE69535704T2 DE69535704T2 (de) | 2009-02-12 |
Family
ID=22808753
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69535704T Expired - Lifetime DE69535704T2 (de) | 1994-03-22 | 1995-03-22 | EXPRESSIONSPLASMIDE, DURCH EINEN osmB PROMOTER REGULIERT |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US5795776A (de) |
| EP (1) | EP0764202B1 (de) |
| JP (2) | JP3878207B2 (de) |
| AT (1) | ATE386101T1 (de) |
| AU (1) | AU2126695A (de) |
| DE (1) | DE69535704T2 (de) |
| IL (1) | IL113031A (de) |
| WO (1) | WO1995025785A1 (de) |
| ZA (1) | ZA952056B (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2316475T (pt) | 1998-08-06 | 2017-12-21 | Univ Duke | Uricase tetramérica isolada |
| US20040001839A1 (en) * | 2000-12-29 | 2004-01-01 | Avigdor Levanon | Multimers - isolated molecules comprising epitopes containing sulfated moieties, antibodies to such epitopes, and uses thereof |
| US20040001822A1 (en) * | 2000-12-29 | 2004-01-01 | Avigdor Levanon | Y1-isolated molecules comprising epitopes containing sulfated moieties, antibodies to such epitopes, and uses thereof |
| US7132510B2 (en) * | 2000-12-29 | 2006-11-07 | Bio-Technology General (Israel) Ltd. | Specific human antibodies for selective cancer therapy |
| US20040002450A1 (en) * | 2000-12-29 | 2004-01-01 | Janette Lazarovits | Y17 - isolated molecules comprising epitopes containing sulfated moieties, antibodies to such epitopes, and uses thereof |
| US20040208877A1 (en) * | 2002-07-01 | 2004-10-21 | Avigdor Levanon | Antibodies and uses thereof |
| US20040202665A1 (en) * | 2002-07-01 | 2004-10-14 | Janette Lazarovits | Compositions and methods for therapeutic treatment |
| US20050152906A1 (en) * | 2003-06-30 | 2005-07-14 | Avigdor Levanon | Specific human antibodies |
| US20050266009A1 (en) * | 2003-06-30 | 2005-12-01 | Savient Pharmaceuticals, Inc. | Antibodies and uses thereof |
| US20050069955A1 (en) * | 2003-06-30 | 2005-03-31 | Daniel Plaksin | Antibodies and uses thereof |
| HU229626B1 (hu) | 2005-04-11 | 2014-03-28 | Savient Pharmaceuticals | Urát oxidáz változat és alkalmazása |
| EP1871874B1 (de) | 2005-04-11 | 2015-04-08 | Crealta Pharmaceuticals LLC | Varianten der uricase und deren verwendung |
| RU2535038C2 (ru) | 2009-06-25 | 2014-12-10 | Криэлта Фармасьютикалз ЭлЭлСи | Способы и наборы для прогнозирования риска инфузионных реакций и опосредованной антителами потери ответа при терапии пэгилированной уриказой с помощью мониторинга содержания мочевой кислоты в сыворотке крови |
| EP2784159B1 (de) * | 2011-11-25 | 2018-05-09 | SNU R&DB Foundation | Cis-regulierendes element aus hepatitis-b-virus und dessen verwendung |
| CN108291243A (zh) | 2015-11-27 | 2018-07-17 | 赢创德固赛有限公司 | 生产l-甲硫氨酸的方法 |
| CN110234340A (zh) | 2016-11-11 | 2019-09-13 | 好利恩风湿病制药有限责任公司 | 泼尼松和尿酸酶分子的组合疗法及其用途 |
| WO2020160325A1 (en) | 2019-01-30 | 2020-08-06 | Horizon Pharma Rheumatology Llc | Reducing immunogenicity to pegloticase |
| CA3213902A1 (en) | 2021-04-01 | 2022-10-06 | Markus Potter | Enzymatic method for producing l-glufosinate and its phosphoesters |
| EP4105335A1 (de) | 2021-06-16 | 2022-12-21 | Evonik Operations GmbH | Enzymatisches verfahren zur herstellung von l-glufosinat-p-alkylestern |
| WO2023174511A1 (en) | 2022-03-14 | 2023-09-21 | Evonik Operations Gmbh | Enzymatic method for the production of l-glufosinate p-esters |
| WO2023222227A1 (en) | 2022-05-19 | 2023-11-23 | Evonik Operations Gmbh | Enzymatic method for producing l-glufosinate |
| WO2023222226A1 (en) | 2022-05-19 | 2023-11-23 | Evonik Operations Gmbh | Enzymatic method for producing l-glufosinate |
| WO2023232225A1 (en) | 2022-05-31 | 2023-12-07 | Evonik Operations Gmbh | Enzymatic method for the diastereoselective production of l-glufosinate p-esters |
| AU2022479282A1 (en) | 2022-09-21 | 2025-05-01 | Evonik Operations Gmbh | Enzymatic method for producing l-glufosinate and its phosphoesters |
| WO2024061456A1 (en) | 2022-09-21 | 2024-03-28 | Evonik Operations Gmbh | Enzymatic method for producing l-glufosinate and its phosphoesters |
| US12269875B2 (en) | 2023-08-03 | 2025-04-08 | Jeff R. Peterson | Gout flare prevention methods using IL-1BETA blockers |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4666836A (en) * | 1981-01-02 | 1987-05-19 | The Research Foundation Of State University Of New York | Novel cloning vehicles for polypeptide expression in microbial hosts |
| US4624926A (en) * | 1981-01-02 | 1986-11-25 | The Research Foundation Of State University Of New York | Novel cloning vehicles for polypeptide expression in microbial hosts |
| DK582381A (da) * | 1981-01-02 | 1982-07-03 | Univ New York | Remkombinat plasmid til anvendelse ved bakteriel kloning |
| US4863855A (en) * | 1982-05-14 | 1989-09-05 | The Research Foundation Of State University Of New York | Novel cloning vehicles for polypeptide expression in microbial hosts |
| US4745069A (en) * | 1982-05-25 | 1988-05-17 | Eli Lilly And Company | Cloning vectors for expression of exogenous protein |
| GB2121054B (en) * | 1982-05-25 | 1986-02-26 | Lilly Co Eli | Cloning vectors for expression of exogenous protein |
| JPS59203495A (ja) * | 1983-04-28 | 1984-11-17 | Kyowa Hakko Kogyo Co Ltd | 外来遺伝子の新規な発現方法 |
| US4757013A (en) * | 1983-07-25 | 1988-07-12 | The Research Foundation Of State University Of New York | Cloning vehicles for polypeptide expression in microbial hosts |
| US4643969A (en) * | 1983-07-25 | 1987-02-17 | The Research Foundation Of State University Of New York | Novel cloning vehicles for polypeptide expression in microbial hosts |
| DE3445517C2 (de) * | 1984-12-13 | 1993-11-18 | Ciba Geigy | Für ein Hirudin-ähnliches Protein codierende DNA-Sequenz und Verfahren zur Herstellung eines Hirudin-ähnlichen Proteins |
| US4987070A (en) * | 1987-03-04 | 1991-01-22 | Suntory Limited | Use of a 97 amino acid leader sequence from the E. coli B-galactosidase gene for the production of hanp and hptc as fusion proteins |
| US5063158A (en) * | 1987-11-09 | 1991-11-05 | Eli Lilly And Company | Recombinant DNA expression vector comprising both transcriptional and translational activating sequences |
| US5348867A (en) * | 1991-11-15 | 1994-09-20 | George Georgiou | Expression of proteins on bacterial surface |
-
1994
- 1994-03-22 US US08/216,851 patent/US5795776A/en not_active Expired - Lifetime
-
1995
- 1995-03-13 ZA ZA952056A patent/ZA952056B/xx unknown
- 1995-03-19 IL IL113031A patent/IL113031A/en not_active IP Right Cessation
- 1995-03-22 JP JP52481395A patent/JP3878207B2/ja not_active Expired - Lifetime
- 1995-03-22 AU AU21266/95A patent/AU2126695A/en not_active Abandoned
- 1995-03-22 WO PCT/US1995/003622 patent/WO1995025785A1/en not_active Ceased
- 1995-03-22 EP EP95914162A patent/EP0764202B1/de not_active Expired - Lifetime
- 1995-03-22 AT AT95914162T patent/ATE386101T1/de not_active IP Right Cessation
- 1995-03-22 DE DE69535704T patent/DE69535704T2/de not_active Expired - Lifetime
-
1997
- 1997-07-18 US US08/897,043 patent/US5945304A/en not_active Expired - Lifetime
-
2005
- 2005-10-05 JP JP2005292784A patent/JP2006068019A/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| ATE386101T1 (de) | 2008-03-15 |
| EP0764202A1 (de) | 1997-03-26 |
| EP0764202A4 (de) | 1998-01-07 |
| EP0764202B1 (de) | 2008-02-13 |
| IL113031A0 (en) | 1995-06-29 |
| WO1995025785A1 (en) | 1995-09-28 |
| IL113031A (en) | 2006-07-05 |
| AU2126695A (en) | 1995-10-09 |
| US5945304A (en) | 1999-08-31 |
| JP2006068019A (ja) | 2006-03-16 |
| ZA952056B (en) | 1995-12-11 |
| DE69535704T2 (de) | 2009-02-12 |
| JPH10500565A (ja) | 1998-01-20 |
| US5795776A (en) | 1998-08-18 |
| JP3878207B2 (ja) | 2007-02-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |