DE69500673D1 - Arzneimittel zur therapeutischen und prophylaktischen Behandlung von Krankheiten, die durch Hyperplasie der glatten Muskelzellen bedingt sind - Google Patents
Arzneimittel zur therapeutischen und prophylaktischen Behandlung von Krankheiten, die durch Hyperplasie der glatten Muskelzellen bedingt sindInfo
- Publication number
- DE69500673D1 DE69500673D1 DE69500673T DE69500673T DE69500673D1 DE 69500673 D1 DE69500673 D1 DE 69500673D1 DE 69500673 T DE69500673 T DE 69500673T DE 69500673 T DE69500673 T DE 69500673T DE 69500673 D1 DE69500673 D1 DE 69500673D1
- Authority
- DE
- Germany
- Prior art keywords
- therapeutic
- smooth muscle
- prophylactic treatment
- hyperplasia
- medicines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 206010020718 hyperplasia Diseases 0.000 title abstract 2
- 238000011321 prophylaxis Methods 0.000 title abstract 2
- 210000000329 smooth muscle myocyte Anatomy 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- LETVJWLLIMJADE-UHFFFAOYSA-N pyridazin-3-amine Chemical class NC1=CC=CN=N1 LETVJWLLIMJADE-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10536794 | 1994-05-19 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69500673D1 true DE69500673D1 (de) | 1997-10-16 |
| DE69500673T2 DE69500673T2 (de) | 1998-03-19 |
Family
ID=14405751
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69500673T Expired - Fee Related DE69500673T2 (de) | 1994-05-19 | 1995-05-16 | Arzneimittel zur therapeutischen und prophylaktischen Behandlung von Krankheiten, die durch Hyperplasie der glatten Muskelzellen bedingt sind |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5643911A (de) |
| EP (1) | EP0682947B1 (de) |
| CN (1) | CN1116526A (de) |
| AT (1) | ATE157871T1 (de) |
| CA (1) | CA2149691A1 (de) |
| DE (1) | DE69500673T2 (de) |
| DK (1) | DK0682947T3 (de) |
| ES (1) | ES2109752T3 (de) |
| GR (1) | GR3025568T3 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5716956A (en) * | 1995-06-07 | 1998-02-10 | Bearsden Bearsden Bio, Inc. | Dihydrophthalazine antagonists of excitatory amino acid receptors |
| CN1103591C (zh) * | 1996-05-22 | 2003-03-26 | 永光制药有限公司 | 取代的1,4,5,6－四氢哒嗪并[4,5－c]哒嗪－5－酮类化合物之药物组合物及其应用和制备方法 |
| US6689883B1 (en) | 1999-09-28 | 2004-02-10 | Bayer Pharmaceuticals Corporation | Substituted pyridines and pyridazines with angiogenesis inhibiting activity |
| US7977333B2 (en) | 2000-04-20 | 2011-07-12 | Bayer Healthcare Llc | Substituted pyridines and pyridazines with angiogenesis inhibiting activity |
| US6903101B1 (en) | 2000-08-10 | 2005-06-07 | Bayer Pharmaceuticals Corporation | Substituted pyridazines and fused pyridazines with angiogenesis inhibiting activity |
| ATE480527T1 (de) * | 2001-12-11 | 2010-09-15 | Kyowa Hakko Kirin Co Ltd | Thiadiazolinderivate zur krebsbehandlung |
| CA2504540C (en) * | 2002-11-08 | 2012-01-24 | Tyco Healthcare Group Lp | Self-sealing cannula |
| EP1616576A4 (de) * | 2003-04-08 | 2010-02-10 | Mitsubishi Tanabe Pharma Corp | Spezifischer nad(p)h oxidase-hemmer |
| ES2394850T3 (es) | 2003-04-18 | 2013-02-06 | Kyowa Hakko Kirin Co., Ltd. | Inhibidor de cinesina mitótica |
| KR20060014071A (ko) * | 2003-06-10 | 2006-02-14 | 교와 핫꼬 고교 가부시끼가이샤 | 티아디아졸린 유도체 |
| JPWO2006101103A1 (ja) * | 2005-03-22 | 2008-09-04 | 協和醗酵工業株式会社 | 造血器腫瘍治療剤 |
| TW200714593A (en) * | 2005-03-22 | 2007-04-16 | Kyowa Hakko Kogyo Kk | Agent for treatment of solid tumor |
| JPWO2006137490A1 (ja) * | 2005-06-24 | 2009-01-22 | 協和発酵キリン株式会社 | 再狭窄治療剤 |
| US8025640B2 (en) | 2008-06-27 | 2011-09-27 | Tyco Healthcare Group Lp | Pressurized surgical valve |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3738371A (en) | 1970-12-11 | 1973-06-12 | Esb Inc | Cardiac pacers with source condition-responsive rate |
| JPS5748972A (en) | 1980-09-10 | 1982-03-20 | Mitsubishi Yuka Yakuhin Kk | 4-phenylphthalazine derivative |
| JPS5653660A (en) | 1979-10-09 | 1981-05-13 | Mitsubishi Yuka Yakuhin Kk | 4-phenylphthalazine derivative |
| JPS5653659A (en) | 1979-10-09 | 1981-05-13 | Mitsubishi Yuka Yakuhin Kk | Blood platelet coagulation suppressing agent |
| JPS5738715A (en) | 1980-08-18 | 1982-03-03 | Mochida Pharmaceut Co Ltd | Medical composition having activity of prohibiting artery wall from thickening |
| JPS60218377A (ja) | 1984-04-16 | 1985-11-01 | Mitsubishi Yuka Yakuhin Kk | ４−フエニルフタラジン誘導体及びそれを有効成分とする循環改善剤 |
| JPS60243074A (ja) | 1985-04-15 | 1985-12-03 | Mitsubishi Yuka Yakuhin Kk | ４−フエニルフタラジン誘導体 |
| ZA896851B (en) | 1988-09-14 | 1990-06-27 | Hoffmann La Roche | Use of ace-inhibitors |
| DE3926606A1 (de) | 1989-08-11 | 1991-02-14 | Hoechst Ag | Verfahren zur behandlung der cardialen sowie der vasculaeren hypertrophie und hyperplasie |
| JPH0383923A (ja) | 1989-08-25 | 1991-04-09 | Terumo Corp | 中膜平滑筋細胞の遊走阻害剤 |
| JPH03106873A (ja) * | 1989-09-20 | 1991-05-07 | Morishita Pharmaceut Co Ltd | １―ピリジルフタラジン誘導体及びそれらを含有する血小板凝集抑制剤 |
| JP2852538B2 (ja) | 1989-09-29 | 1999-02-03 | 第一製薬株式会社 | 〔１，２，４〕トリアゾロ〔１，５―ａ〕ピリミジン誘導体 |
| DE69105572T2 (de) * | 1990-03-30 | 1995-05-11 | Mitsubishi Chem Ind | 4-Phenylphthalazin-Derivate. |
| JPH04211666A (ja) | 1990-03-30 | 1992-08-03 | Mitsubishi Kasei Corp | ４−フェニルフタラジン誘導体 |
| JP2999808B2 (ja) | 1990-08-20 | 2000-01-17 | 第一製薬株式会社 | ２位置換トリアゾロピリミジン類 |
| JPH04154720A (ja) | 1990-10-16 | 1992-05-27 | Terumo Corp | カテコール誘導体及びこれを含有する血管壁肥厚防止薬 |
| TW279162B (de) | 1991-09-26 | 1996-06-21 | Mitsubishi Chem Corp |
-
1995
- 1995-05-16 AT AT95107372T patent/ATE157871T1/de not_active IP Right Cessation
- 1995-05-16 EP EP95107372A patent/EP0682947B1/de not_active Expired - Lifetime
- 1995-05-16 US US08/441,743 patent/US5643911A/en not_active Expired - Fee Related
- 1995-05-16 DE DE69500673T patent/DE69500673T2/de not_active Expired - Fee Related
- 1995-05-16 DK DK95107372.5T patent/DK0682947T3/da active
- 1995-05-16 ES ES95107372T patent/ES2109752T3/es not_active Expired - Lifetime
- 1995-05-18 CA CA002149691A patent/CA2149691A1/en not_active Abandoned
- 1995-05-18 CN CN95106317.0A patent/CN1116526A/zh active Pending
-
1997
- 1997-12-02 GR GR970403218T patent/GR3025568T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US5643911A (en) | 1997-07-01 |
| EP0682947B1 (de) | 1997-09-10 |
| DE69500673T2 (de) | 1998-03-19 |
| ES2109752T3 (es) | 1998-01-16 |
| CA2149691A1 (en) | 1995-11-20 |
| DK0682947T3 (da) | 1998-05-04 |
| GR3025568T3 (en) | 1998-03-31 |
| CN1116526A (zh) | 1996-02-14 |
| EP0682947A1 (de) | 1995-11-22 |
| ATE157871T1 (de) | 1997-09-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |