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DE60309926D1 - Steroid-verbindungen mit anti-tumoraler wirkung - Google Patents

Steroid-verbindungen mit anti-tumoraler wirkung

Info

Publication number
DE60309926D1
DE60309926D1 DE60309926T DE60309926T DE60309926D1 DE 60309926 D1 DE60309926 D1 DE 60309926D1 DE 60309926 T DE60309926 T DE 60309926T DE 60309926 T DE60309926 T DE 60309926T DE 60309926 D1 DE60309926 D1 DE 60309926D1
Authority
DE
Germany
Prior art keywords
steroid compounds
present
steroid
relates
tumoral effect
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60309926T
Other languages
English (en)
Other versions
DE60309926T2 (de
Inventor
Jean-Claude Braekman
Quaquebeke Eric Van
Laurent Ingrassia
Janique Dewelle
Robert Kiss
Francis Darro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Unibioscreen SA
Universite Libre de Bruxelles ULB
Original Assignee
Unibioscreen SA
Universite Libre de Bruxelles ULB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unibioscreen SA, Universite Libre de Bruxelles ULB filed Critical Unibioscreen SA
Publication of DE60309926D1 publication Critical patent/DE60309926D1/de
Application granted granted Critical
Publication of DE60309926T2 publication Critical patent/DE60309926T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J17/00Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
DE60309926T 2002-12-18 2003-12-18 Steroid-verbindungen mit anti-tumoraler wirkung Expired - Fee Related DE60309926T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP02447257 2002-12-18
EP02447257 2002-12-18
US43583402P 2002-12-20 2002-12-20
US435834P 2002-12-20
PCT/EP2003/014567 WO2004055039A1 (en) 2002-12-18 2003-12-18 Steroid compounds with anti-tumor activity

Publications (2)

Publication Number Publication Date
DE60309926D1 true DE60309926D1 (de) 2007-01-04
DE60309926T2 DE60309926T2 (de) 2007-09-13

Family

ID=32598801

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60309926T Expired - Fee Related DE60309926T2 (de) 2002-12-18 2003-12-18 Steroid-verbindungen mit anti-tumoraler wirkung

Country Status (14)

Country Link
US (1) US20060149045A1 (de)
EP (1) EP1572715B1 (de)
JP (1) JP2006511544A (de)
CN (1) CN100402546C (de)
AT (1) ATE346080T1 (de)
AU (1) AU2003293943B2 (de)
CA (1) CA2509283A1 (de)
DE (1) DE60309926T2 (de)
DK (1) DK1572715T3 (de)
ES (1) ES2277138T3 (de)
MX (1) MXPA05006378A (de)
PT (1) PT1572715E (de)
WO (1) WO2004055039A1 (de)
ZA (1) ZA200504777B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101352635B1 (ko) * 2011-12-29 2014-01-20 연세대학교 산학협력단 신규 혈관누출 차단제
EP3162875B1 (de) * 2015-10-30 2018-05-23 Merck Patent GmbH Polymerisierbare verbindungen und verwendung davon in flüssigkristallanzeigevorrichtungen
US10434106B2 (en) * 2017-05-19 2019-10-08 Warsaw Orthopedic, Inc. Oxysterol-statin compounds for bone growth

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3584050B2 (ja) * 1993-05-14 2004-11-04 株式会社医薬分子設計研究所 ステロイド化合物

Also Published As

Publication number Publication date
ES2277138T3 (es) 2007-07-01
DK1572715T3 (da) 2007-04-02
AU2003293943A1 (en) 2004-07-09
EP1572715A1 (de) 2005-09-14
CN100402546C (zh) 2008-07-16
JP2006511544A (ja) 2006-04-06
PT1572715E (pt) 2007-01-31
WO2004055039A1 (en) 2004-07-01
DE60309926T2 (de) 2007-09-13
EP1572715B1 (de) 2006-11-22
CA2509283A1 (en) 2004-07-01
US20060149045A1 (en) 2006-07-06
CN1745090A (zh) 2006-03-08
ATE346080T1 (de) 2006-12-15
ZA200504777B (en) 2006-04-26
MXPA05006378A (es) 2006-02-08
HK1085744A1 (en) 2006-09-01
AU2003293943B2 (en) 2009-08-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee