DE60302764D1 - TEST ON PHOSPHOAMIDASE - Google Patents
TEST ON PHOSPHOAMIDASEInfo
- Publication number
- DE60302764D1 DE60302764D1 DE60302764T DE60302764T DE60302764D1 DE 60302764 D1 DE60302764 D1 DE 60302764D1 DE 60302764 T DE60302764 T DE 60302764T DE 60302764 T DE60302764 T DE 60302764T DE 60302764 D1 DE60302764 D1 DE 60302764D1
- Authority
- DE
- Germany
- Prior art keywords
- phosphoamidases
- phosphoamidase
- test
- phosphoarginine
- phospholysine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 102100025683 Alkaline phosphatase, tissue-nonspecific isozyme Human genes 0.000 title abstract 3
- 108010003781 Phosphoamidase Proteins 0.000 title abstract 3
- HIUQIUQSEYDPNQ-YFKPBYRVSA-N (2s)-6-amino-2-(phosphonoamino)hexanoic acid Chemical compound NCCCC[C@@H](C(O)=O)NP(O)(O)=O HIUQIUQSEYDPNQ-YFKPBYRVSA-N 0.000 abstract 1
- UZGKAASZIMOAMU-UHFFFAOYSA-N 124177-85-1 Chemical compound NP(=O)=O UZGKAASZIMOAMU-UHFFFAOYSA-N 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- CCTIOCVIZPCTGO-BYPYZUCNSA-N phosphoarginine Chemical compound OC(=O)[C@@H](N)CCCNC(=N)NP(O)(O)=O CCTIOCVIZPCTGO-BYPYZUCNSA-N 0.000 abstract 1
- FDIKHVQUPVCJFA-UHFFFAOYSA-N phosphohistidine Chemical compound OP(=O)(O)NC(C(=O)O)CC1=CN=CN1 FDIKHVQUPVCJFA-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/44—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
The present invention relates to the use of compounds and to methods for the qualitative and/or quantitative determination of the activity of phosphoamidases or protein phosphoamidases specific for hydrolyzing phosphoamide (P-N) bonds N-phosphorylated basic amino acids like phospholysine, phosphoarginine and phosphohistidine.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02025128 | 2002-11-09 | ||
| EP02025128 | 2002-11-09 | ||
| PCT/EP2003/011253 WO2004044233A1 (en) | 2002-11-09 | 2003-10-10 | Phosphoamidase assay |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60302764D1 true DE60302764D1 (en) | 2006-01-19 |
| DE60302764T2 DE60302764T2 (en) | 2006-09-14 |
Family
ID=32309331
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60302764T Expired - Fee Related DE60302764T2 (en) | 2002-11-09 | 2003-10-10 | TEST ON PHOSPHOAMIDASE |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7348160B2 (en) |
| EP (1) | EP1468108B1 (en) |
| AT (1) | ATE312941T1 (en) |
| AU (1) | AU2003280359A1 (en) |
| DE (1) | DE60302764T2 (en) |
| ES (1) | ES2254977T3 (en) |
| WO (1) | WO2004044233A1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7217523B2 (en) * | 2004-07-02 | 2007-05-15 | Regents Of The University Of Minnesota | Nucleoside phosphoramidates and nucleoside phosphoramidases |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60038731T2 (en) * | 1999-03-04 | 2009-07-02 | Merck Patent Gmbh | HISTIDINE PROTEIN PHOSPHATASE |
-
2003
- 2003-10-10 ES ES03770968T patent/ES2254977T3/en not_active Expired - Lifetime
- 2003-10-10 WO PCT/EP2003/011253 patent/WO2004044233A1/en not_active Ceased
- 2003-10-10 EP EP03770968A patent/EP1468108B1/en not_active Expired - Lifetime
- 2003-10-10 AU AU2003280359A patent/AU2003280359A1/en not_active Abandoned
- 2003-10-10 DE DE60302764T patent/DE60302764T2/en not_active Expired - Fee Related
- 2003-10-10 AT AT03770968T patent/ATE312941T1/en not_active IP Right Cessation
- 2003-10-10 US US10/501,077 patent/US7348160B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004044233A1 (en) | 2004-05-27 |
| EP1468108A1 (en) | 2004-10-20 |
| US20050124023A1 (en) | 2005-06-09 |
| EP1468108B1 (en) | 2005-12-14 |
| ES2254977T3 (en) | 2006-06-16 |
| ATE312941T1 (en) | 2005-12-15 |
| DE60302764T2 (en) | 2006-09-14 |
| AU2003280359A1 (en) | 2004-06-03 |
| US7348160B2 (en) | 2008-03-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |