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DE60228184D1 - Verfahren zur Herstellung von Chondroitinsulfaten aus K4-Polysaccharid und so hergestellte Produkte - Google Patents

Verfahren zur Herstellung von Chondroitinsulfaten aus K4-Polysaccharid und so hergestellte Produkte

Info

Publication number
DE60228184D1
DE60228184D1 DE60228184T DE60228184T DE60228184D1 DE 60228184 D1 DE60228184 D1 DE 60228184D1 DE 60228184 T DE60228184 T DE 60228184T DE 60228184 T DE60228184 T DE 60228184T DE 60228184 D1 DE60228184 D1 DE 60228184D1
Authority
DE
Germany
Prior art keywords
preparation
polysaccharide
products
produced
chondroitin sulfates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60228184T
Other languages
English (en)
Inventor
Giorgio Zoppetti
Pasqua Oreste
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IBSA Institut Biochimique SA
Original Assignee
IBSA Institut Biochimique SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IBSA Institut Biochimique SA filed Critical IBSA Institut Biochimique SA
Application granted granted Critical
Publication of DE60228184D1 publication Critical patent/DE60228184D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60228184T 2001-10-22 2002-10-18 Verfahren zur Herstellung von Chondroitinsulfaten aus K4-Polysaccharid und so hergestellte Produkte Expired - Lifetime DE60228184D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2001MI002200A ITMI20012200A1 (it) 2001-10-22 2001-10-22 Processo per la preparazione di condroitin solfati dal polisaccaride k4 e prodotti ottenuti

Publications (1)

Publication Number Publication Date
DE60228184D1 true DE60228184D1 (de) 2008-09-25

Family

ID=11448534

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60228184T Expired - Lifetime DE60228184D1 (de) 2001-10-22 2002-10-18 Verfahren zur Herstellung von Chondroitinsulfaten aus K4-Polysaccharid und so hergestellte Produkte

Country Status (7)

Country Link
US (1) US6777398B2 (de)
EP (1) EP1304338B1 (de)
AT (1) ATE404588T1 (de)
CA (1) CA2408681A1 (de)
DE (1) DE60228184D1 (de)
ES (1) ES2312519T3 (de)
IT (1) ITMI20012200A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080108110A1 (en) * 1998-04-02 2008-05-08 Deangelis Paul L Targeted glycosaminoglycan polymers by polymer grafting and methods of making and using same
US7223571B2 (en) 1998-04-02 2007-05-29 The Board Of Regents Of The Universtiy Of Oklahoma Targeted glycosaminoglycan polymers by polymer grafting and methods of making and using same
US20060188966A1 (en) 1998-04-02 2006-08-24 Deangelis Paul L Natural, chimeric and hybrid glycosaminoglycan polymers and methods of making and using same
US20030104601A1 (en) 1999-04-01 2003-06-05 Deangelis Paul L. Chondroitin synthase gene and methods of making and using same
US7642071B2 (en) 1999-04-01 2010-01-05 The Board Of Regents Of The University Of Oklahoma Methods of expressing gram-negative glycosaminoglycan synthase genes in gram-positive hosts
ITMI20032498A1 (it) 2003-12-17 2005-06-18 Pasqua Anna Oreste Polisaccaridi antitrombotici a basso peso molecolare e
ITMI20010397A1 (it) * 2001-02-27 2002-08-27 Giorgio Zoppetti Derivati altamente n,o-solfatati del polisaccaride k5 e loro preparazione
US8513407B2 (en) * 2002-06-18 2013-08-20 Glycores 2000 S.R.L. Process for the preparation of N-acyl-(epi)K5-amine-O-sulfate-derivatives and products thus obtained
US7838644B2 (en) * 2002-06-18 2010-11-23 Glycores 2000 S.R.L. Epimerized derivatives of K5 polysaccharide with a very high degree of sulfation
ES2405314T3 (es) 2008-05-13 2013-05-30 Apharm S.R.L. Composiciones y uso oral de glicosaminoglicanos
WO2009149155A1 (en) * 2008-06-04 2009-12-10 Amano Enzyme Usa., Ltd. Microbial-derived chondroitin sulfate
IT1394311B1 (it) * 2009-05-25 2012-06-06 Altergon Sa Produzione biotecnologica di condroitina
ITMI20110505A1 (it) * 2011-03-29 2012-09-30 Altergon Sa Processo per la preparazione di condroitine solfatate in posizione 3 sull'acido glucuronico
ITMI20120136A1 (it) * 2012-02-02 2013-08-03 Gnosis Spa Condroitin solfato biotecnologico a basso peso molecolare solfatato in posizione 4 o 6 sulla stessa catena polisaccaridica dotato di attivita' antiinfiammatoria e antiartritica e procedimento per la sua preparazione
CN103582653B (zh) * 2011-05-12 2016-08-17 诺西斯有限公司 在同一多糖链的4位或6位生物技术硫酸化的硫酸软骨素及其制备方法
ITMI20110829A1 (it) * 2011-05-12 2012-11-13 Gnosis Spa Condroitin solfato biotecnologico solfatato in posizione 4 o 6 sulla stessa catena polisaccaridica e procedimento per la sua preparazione
US8664196B2 (en) 2011-05-20 2014-03-04 Gnosis S.P.A. Shark-like chondroitin sulphate and process for the preparation thereof
AU2011369262B2 (en) * 2011-05-20 2017-02-02 Lesaffre Et Compagnie Shark-like chondroitin sulphate and process for the preparation thereof
CN102618597A (zh) * 2012-04-06 2012-08-01 江南大学 大肠杆菌工程菌及其生产软骨素的方法
ITMI20120880A1 (it) 2012-05-22 2013-11-23 Gnosis Spa Condroitin 6-solfato biotecnologico a basso peso molecolare dotato di attivita' antiinfiammatoria e antiartritica e suo uso nel trattamento e nella prevenzione dell'osteoartrite
ITMI20120896A1 (it) 2012-05-23 2013-11-24 Bongulielmi Reto Condroitina per uso in medicina
ITMI20121316A1 (it) 2012-07-27 2014-01-28 Altergon Sa Complessi di condroitina ad assorbimento transcutaneo
ITMI20130117A1 (it) * 2013-01-25 2014-07-26 Gnosis Spa Composizioni comprendenti condroitin solfato, enzimi proteolitici e composti sulfidrilati capaci di migliorare la biodisponibilita' del condroitin solfato
CN104163877B (zh) * 2014-08-26 2016-05-18 淮安麦德森制药有限公司 硫酸软骨素的制备方法
EP3240550B1 (de) 2015-10-01 2019-04-10 Apharm S.r.l. Kombination aus glucosaminoglykanen und einem antazidum und zusammensetzungen davon
CN108484795B (zh) * 2018-04-28 2021-02-09 山东第一医科大学第二附属医院 硫酸软骨素锂及其制备方法和应用
CN111662394B (zh) * 2019-03-05 2022-11-04 中国医学科学院药物研究所 硫酸软骨素多糖半合成制备方法和应用
IT202000013633A1 (it) * 2020-06-08 2021-12-08 Vivatis Pharma Gmbh Processo di estrazione di una condroitina solfato da un fungo, una condroitina solfato di origine vegetale e suo uso
CN115353574B (zh) * 2022-09-06 2023-06-13 福建省深蓝生物科技有限公司 高硫酸化度的硫酸软骨素cs-e及其提取方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3895107A (en) * 1970-04-15 1975-07-15 Morrison L M CSA and CSC in man and mammals to inhibit atherosclerosis and the recurrence of cardiovascular incidents in atherosclerotic mammals
US4302577A (en) * 1979-10-05 1981-11-24 Biomed Research Inc. Process for preparing CSA or CSC
IT1289613B1 (it) * 1997-02-07 1998-10-15 Inalco Spa Polisaccaridi batterici o-solfatati
ITMI991465A1 (it) 1999-07-02 2001-01-02 Inalco Spa Processo per la preparazione dei polisaccaridi k4 e k5 da escherichiacoli

Also Published As

Publication number Publication date
ITMI20012200A1 (it) 2003-04-22
US6777398B2 (en) 2004-08-17
ATE404588T1 (de) 2008-08-15
EP1304338A1 (de) 2003-04-23
ES2312519T3 (es) 2009-03-01
US20030100534A1 (en) 2003-05-29
EP1304338B1 (de) 2008-08-13
CA2408681A1 (en) 2003-04-22

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