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DE602004024899D1 - Verfahren und vorrichtung zur handhabung von kleinvolumigen fluidproben - Google Patents

Verfahren und vorrichtung zur handhabung von kleinvolumigen fluidproben

Info

Publication number
DE602004024899D1
DE602004024899D1 DE602004024899T DE602004024899T DE602004024899D1 DE 602004024899 D1 DE602004024899 D1 DE 602004024899D1 DE 602004024899 T DE602004024899 T DE 602004024899T DE 602004024899 T DE602004024899 T DE 602004024899T DE 602004024899 D1 DE602004024899 D1 DE 602004024899D1
Authority
DE
Germany
Prior art keywords
small volume
fluid samples
volume fluid
handling small
valve
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602004024899T
Other languages
English (en)
Inventor
Peter Massaro
Benjamin F Geldhof
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Protedyne Corp
Original Assignee
Protedyne Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Protedyne Corp filed Critical Protedyne Corp
Publication of DE602004024899D1 publication Critical patent/DE602004024899D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1016—Control of the volume dispensed or introduced
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
    • B01L2300/0838—Capillaries
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0666—Solenoid valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1034—Transferring microquantities of liquid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Sampling And Sample Adjustment (AREA)
DE602004024899T 2003-08-15 2004-08-13 Verfahren und vorrichtung zur handhabung von kleinvolumigen fluidproben Expired - Lifetime DE602004024899D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/641,523 US7097070B2 (en) 2003-08-15 2003-08-15 Method and apparatus for handling small volume fluid samples
PCT/US2004/026453 WO2005016535A1 (en) 2003-08-15 2004-08-13 Method and apparatus for handling small volume fluid samples

Publications (1)

Publication Number Publication Date
DE602004024899D1 true DE602004024899D1 (de) 2010-02-11

Family

ID=34136375

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004024899T Expired - Lifetime DE602004024899D1 (de) 2003-08-15 2004-08-13 Verfahren und vorrichtung zur handhabung von kleinvolumigen fluidproben

Country Status (7)

Country Link
US (1) US7097070B2 (de)
EP (1) EP1663494B1 (de)
JP (1) JP2007502986A (de)
AT (1) ATE453451T1 (de)
DE (1) DE602004024899D1 (de)
DK (1) DK1663494T3 (de)
WO (1) WO2005016535A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7597520B2 (en) * 2005-05-24 2009-10-06 Festo Corporation Apparatus and method for transferring samples from a source to a target
US7534081B2 (en) * 2005-05-24 2009-05-19 Festo Corporation Apparatus and method for transferring samples from a source to a target
US7799281B2 (en) * 2007-01-16 2010-09-21 Festo Corporation Flux concentrator for biomagnetic particle transfer device
US8113390B2 (en) * 2007-04-18 2012-02-14 Microlin, Llc Gas generation dispenser apparatus and method for on-demand fluid delivery
US20100176214A1 (en) * 2009-01-13 2010-07-15 Joshi Ashok V Greeting card fragrance delivery system
US8939435B2 (en) 2011-06-03 2015-01-27 Microlin, Llc Device for delivery of volatile liquids to gaseous environment utilizing a gas generating cell
WO2013094373A1 (ja) * 2011-12-22 2013-06-27 三洋電機株式会社 分注装置
EP3043156B1 (de) * 2015-01-07 2018-03-07 CSEM Centre Suisse d'Electronique et de Microtechnique SA - Recherche et Développement Verfahren zur Abgabe oder Ansaugung von Flüssigkeit
US11320295B2 (en) * 2019-04-26 2022-05-03 Festo Se & Co. Kg Dosing unit and method for dosing a liquid
CN112834770B (zh) * 2019-11-22 2025-02-18 山西恒昌荣医疗器械有限公司 一种用于血栓弹力图仪的前处理设备
JP7495867B2 (ja) * 2020-10-30 2024-06-05 株式会社日立ハイテク 自動分析装置

Family Cites Families (134)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2264564A (en) 1937-10-28 1941-12-02 Connor Arthur Albert Air brush for artists' use
US3575220A (en) * 1968-08-12 1971-04-20 Scientific Industries Apparatus for dispensing liquid sample
US4083690A (en) * 1975-10-02 1978-04-11 Kirin Beer Kabushiki Kaisha Automatic preparation of sample for analysis
US4042152A (en) * 1975-11-21 1977-08-16 Coulter Electronics, Inc. Diluting apparatus
US4058367A (en) 1976-05-19 1977-11-15 Gilford Instrument Laboratories Inc. Automatic asynchronous fluid processing apparatus
US4152390A (en) * 1976-12-17 1979-05-01 Eastman Kodak Company Chemical analyzer
JPS55136958A (en) 1979-04-14 1980-10-25 Olympus Optical Co Ltd Automatic analyzer
US4325910A (en) * 1979-07-11 1982-04-20 Technicraft, Inc. Automated multiple-purpose chemical-analysis apparatus
US4352780A (en) 1979-07-13 1982-10-05 Fiatron Systems, Inc. Device for controlled injection of fluids
US4311484A (en) * 1980-04-09 1982-01-19 Cortex Research Corporation Specimen sampling apparatus
US4323537A (en) * 1980-10-20 1982-04-06 Instrumentation Laboratory Inc. Analysis system
US4351799A (en) * 1981-07-15 1982-09-28 Gross Valery N Micrometering liquid sample dispenser
US4436822A (en) * 1981-09-22 1984-03-13 Sherwood Medical Company Reagent mixing system and method
US4482345A (en) 1982-02-16 1984-11-13 E. R. Squibb & Sons, Inc. Automated control for a two-directional pump
US4454095A (en) * 1982-07-21 1984-06-12 Harbor Branch Foundation, Inc. Automatic chemical analysis devices and methods
US4597412A (en) * 1982-09-29 1986-07-01 Stark Anton W Valve for sequential chemical operations
US4503012A (en) * 1983-04-19 1985-03-05 American Monitor Corporation Reagent dispensing system
US4673657A (en) * 1983-08-26 1987-06-16 The Regents Of The University Of California Multiple assay card and system
US5273715A (en) 1984-03-23 1993-12-28 Applied Biosystems, Inc. Automated system for providing a sequence of chemicals to a reaction process
US4876204A (en) 1984-10-11 1989-10-24 Kabushiki Kaisha Kyoto Daiichi Kagaku Method and apparatus of automatic continuous analysis using analytical implement
JPS61198041A (ja) * 1985-02-28 1986-09-02 Konishiroku Photo Ind Co Ltd 生化学分析装置
DE3683573D1 (de) * 1985-06-26 1992-03-05 Japan Tectron Instr Corp Automatischer analysenapparat.
US4681741A (en) * 1985-07-01 1987-07-21 American Hospital Supply Corporation Reagent dispenser for an analyzing system
US4695430A (en) * 1985-10-31 1987-09-22 Bio/Data Corporation Analytical apparatus
US4863066A (en) * 1986-06-02 1989-09-05 Technicon Instruments Corporation System for dispensing precisely metered quantities of a fluid and method of utilizing the system
US4965049A (en) 1986-07-11 1990-10-23 Beckman Instruments, Inc. Modular analyzer system
US4911195A (en) 1986-08-27 1990-03-27 Porton Instruments, Inc. Valve block assembly
GB2196116B (en) * 1986-10-07 1990-08-15 Weston Terence E Apparatus for chemical analysis.
US4980130A (en) 1986-12-16 1990-12-25 Ciba-Geigy Corporation System for preparation of samples for analysis
US4844872A (en) * 1987-07-17 1989-07-04 Fisher Scientific Company Fluid handling
US4906432B1 (en) * 1987-07-17 1991-06-25 Liquid handling
JPH06103315B2 (ja) * 1987-08-14 1994-12-14 株式会社東芝 自動化学分析装置の分注ノズル装置
US5139743A (en) * 1987-09-24 1992-08-18 Fuji Photo Film Co., Ltd. Biochemical analysis apparatus
US5147608A (en) * 1988-04-29 1992-09-15 Millipore Corporation Apparatus and process for performing repetitive chemical processing
US5019348A (en) * 1988-05-26 1991-05-28 Beckman Instruments, Inc. Automated chemical conversion unit in a peptide/protein sequenator
US4900305A (en) 1988-06-27 1990-02-13 Queen's University At Kingston Ambulatory infusion pump
US5012845A (en) * 1988-08-18 1991-05-07 Dynatech Precision Sampling Corporation Fluid injector
US6306594B1 (en) 1988-11-14 2001-10-23 I-Stat Corporation Methods for microdispensing patterened layers
US5037611A (en) * 1988-11-29 1991-08-06 Icr Research Associates, Inc. Sample handling technique
IT1228238B (it) * 1989-01-16 1991-06-05 Nardo Pietro C Apparecchiatura per il trattamento di schede elettroforetiche.
US5223222A (en) * 1989-03-13 1993-06-29 Beckman Instruments, Inc. Automatic chemistry analyzer
US5213762A (en) * 1989-03-13 1993-05-25 Beckman Instruments, Inc. Automatic chemistry analyzer
US5130095A (en) * 1989-03-13 1992-07-14 Beckman Instruments, Inc. Automatic chemistry analyzer
JPH02242162A (ja) * 1989-03-15 1990-09-26 Takara Shuzo Co Ltd 試薬反応装置
US5056462A (en) 1989-11-27 1991-10-15 Nordson Corporation Coating system with correction for non-linear dispensing characteristics
US5595707A (en) * 1990-03-02 1997-01-21 Ventana Medical Systems, Inc. Automated biological reaction apparatus
US5282978A (en) * 1990-07-09 1994-02-01 Cytyc Corporation Specimen processor method and apparatus
US5085832A (en) * 1990-07-20 1992-02-04 Eastman Kodak Company Dispensing mechanism
DE4024545A1 (de) * 1990-08-02 1992-02-06 Boehringer Mannheim Gmbh Verfahren und vorrichtung zum dosierten zufuehren einer biochemischen analysefluessigkeit auf ein target
US5085402A (en) * 1990-08-10 1992-02-04 The Lee Company High speed solenoid valve actuator
US5143118A (en) * 1991-02-14 1992-09-01 Akos Sule Solenoid control valve
JPH06504136A (ja) * 1991-10-31 1994-05-12 マイクロスキャン、インコーポレイテッド 関連する液体分配装置を備えた標本処理及び分析システム
US5240680A (en) * 1991-12-19 1993-08-31 Chiron Corporation Automated apparatus for use in peptide synthesis
US5635364A (en) * 1992-03-27 1997-06-03 Abbott Laboratories Assay verification control for an automated analytical system
US5646049A (en) * 1992-03-27 1997-07-08 Abbott Laboratories Scheduling operation of an automated analytical system
US5332549A (en) * 1992-07-01 1994-07-26 Pb Diagnostic Systems, Inc. Assay module transport apparatus for use in an automated analytical instrument
US5314825A (en) * 1992-07-16 1994-05-24 Schiapparelli Biosystems, Inc. Chemical analyzer
US5284425A (en) * 1992-11-18 1994-02-08 The Lee Company Fluid metering pump
US5324480A (en) * 1992-12-04 1994-06-28 Hamilton Company Liquid handling system
US5507277A (en) 1993-01-29 1996-04-16 Aradigm Corporation Lockout device for controlled release of drug from patient-activateddispenser
US5525515A (en) * 1993-02-03 1996-06-11 Blattner; Frederick R. Process of handling liquids in an automated liquid handling apparatus
US5334353A (en) * 1993-02-03 1994-08-02 Blattner Frederick R Micropipette device
US5320139A (en) * 1993-03-30 1994-06-14 Millipore Corporation Fluid delivery system
ATE208658T1 (de) * 1993-07-28 2001-11-15 Pe Corp Ny Vorrichtung und verfahren zur nukleinsäurevervielfältigung
RU2041263C1 (ru) * 1993-08-11 1995-08-09 Геннадий Моисеевич Ершов Способ микродозирования водных растворов веществ на носитель и устройство для его осуществления
US5509966A (en) * 1993-10-22 1996-04-23 Sykes; Richard H. Graphic arts material extrusion device
US5411065A (en) * 1994-01-10 1995-05-02 Kvm Technologies, Inc. Liquid specimen transfer apparatus and method
JP3364311B2 (ja) * 1994-03-15 2003-01-08 シスメックス株式会社 定量装置
US5624409A (en) * 1994-06-10 1997-04-29 Fluidsense Corporation Variable-pulse dynamic fluid flow controller
US5948360A (en) * 1994-07-11 1999-09-07 Tekmar Company Autosampler with robot arm
US5549141A (en) * 1994-07-19 1996-08-27 Kvm Technologies, Inc. Liquid container sample transfer method and apparatus
US6558633B1 (en) * 1994-09-21 2003-05-06 Isis Pharmaceuticals, Inc. Chemical reaction apparatus and methods
JP3229915B2 (ja) * 1995-01-19 2001-11-19 日本電子株式会社 生化学自動分析装置
US5568882A (en) 1995-02-03 1996-10-29 Abc Techcorp Precise volume fluid dispenser
US5601982A (en) * 1995-02-07 1997-02-11 Sargent; Jeannine P. Method and apparatus for determining the sequence of polynucleotides
CA2185292A1 (en) * 1995-09-15 1997-03-16 James C. Smith Positive displacement liquid drawing and dispensing apparatus and method
US5797515A (en) 1995-10-18 1998-08-25 Adds, Inc. Method for controlling a drug dispensing system
US5763278A (en) * 1995-11-01 1998-06-09 Tecan Ag Automated pipetting of small volumes
US5697409A (en) 1996-02-21 1997-12-16 Biomerieux Vitek, Inc. Diluting and pipetting stations for sample testing machine
US5762873A (en) * 1996-02-21 1998-06-09 Biomerieux Vitek, Inc. Automatic sample testing machine
US5819799A (en) 1996-05-10 1998-10-13 The Lee Company Method and apparatus for rapid fluid dispensing
US5770151A (en) * 1996-06-05 1998-06-23 Molecular Dynamics, Inc. High-speed liquid deposition device for biological molecule array formation
US5743960A (en) * 1996-07-26 1998-04-28 Bio-Dot, Inc. Precision metered solenoid valve dispenser
US5916524A (en) 1997-07-23 1999-06-29 Bio-Dot, Inc. Dispensing apparatus having improved dynamic range
US5738728A (en) * 1996-07-26 1998-04-14 Bio Dot, Inc. Precision metered aerosol dispensing apparatus
US5741554A (en) * 1996-07-26 1998-04-21 Bio Dot, Inc. Method of dispensing a liquid reagent
US5795784A (en) * 1996-09-19 1998-08-18 Abbott Laboratories Method of performing a process for determining an item of interest in a sample
US5856194A (en) * 1996-09-19 1999-01-05 Abbott Laboratories Method for determination of item of interest in a sample
US5882903A (en) * 1996-11-01 1999-03-16 Sarnoff Corporation Assay system and method for conducting assays
DE69722451T2 (de) * 1996-11-22 2004-05-19 Therakos, Inc. Vorrichtung zum pumpen eines fluides mit einer konstanten durchflussrate
US5897837A (en) * 1997-02-06 1999-04-27 Toa Medical Electronics Co., Ltd. Dispensing device and Immunoassay apparatus using the same
US5875967A (en) * 1997-02-07 1999-03-02 The Lee Company Method and apparatus for dispensing fluid having volatile solvent
US5985214A (en) 1997-05-16 1999-11-16 Aurora Biosciences Corporation Systems and methods for rapidly identifying useful chemicals in liquid samples
US5993627A (en) 1997-06-24 1999-11-30 Large Scale Biology Corporation Automated system for two-dimensional electrophoresis
US6045759A (en) * 1997-08-11 2000-04-04 Ventana Medical Systems Fluid dispenser
DE19737173B4 (de) 1997-08-26 2007-04-05 Eppendorf Ag Mikrodosiersystem
US6102068A (en) * 1997-09-23 2000-08-15 Hewlett-Packard Company Selector valve assembly
IL121968A0 (en) * 1997-10-14 1998-03-10 A R T Medical Instr Ltd Method for depositing a microvolume of liquid on a surface and apparatus therefor and a microvolume pump therefor
KR100279552B1 (ko) * 1997-10-18 2001-11-30 박한오 다중단속밸브장치
US5928131A (en) * 1997-11-26 1999-07-27 Vascor, Inc. Magnetically suspended fluid pump and control system
US6063339A (en) * 1998-01-09 2000-05-16 Cartesian Technologies, Inc. Method and apparatus for high-speed dot array dispensing
US20020159919A1 (en) 1998-01-09 2002-10-31 Carl Churchill Method and apparatus for high-speed microfluidic dispensing using text file control
DE19802368C1 (de) * 1998-01-22 1999-08-05 Hahn Schickard Ges Mikrodosiervorrichtung
US6537505B1 (en) 1998-02-20 2003-03-25 Bio Dot, Inc. Reagent dispensing valve
AU2775799A (en) 1998-02-20 1999-09-06 Cartesian Technologies, Inc. Methods for microfluidic aspirating and dispensing
EP1129008A4 (de) 1998-07-07 2001-12-05 Cartesian Technology Inc Spitzengestaltung und direktzugriffsmatrix für mikro-flüssigkeitstransfer
US6913934B2 (en) 1998-08-13 2005-07-05 Symyx Technologies, Inc. Apparatus and methods for parallel processing of multiple reaction mixtures
JP3525757B2 (ja) * 1998-09-18 2004-05-10 株式会社日立製作所 化学分析装置
EP1154857A4 (de) 1999-02-05 2005-01-19 Invitrogen Corp System, verfahren und computerprogramm-produkt zur automatisierten fluid- oder gaslieferung
US6432719B1 (en) * 1999-02-16 2002-08-13 Pe Corporation (Ny) Matrix storage and dispensing system
US6627157B1 (en) 1999-03-04 2003-09-30 Ut-Battelle, Llc Dual manifold system and method for fluid transfer
US20020176801A1 (en) 1999-03-23 2002-11-28 Giebeler Robert H. Fluid delivery and analysis systems
US6143252A (en) 1999-04-12 2000-11-07 The Perkin-Elmer Corporation Pipetting device with pipette tip for solid phase reactions
US6245297B1 (en) * 1999-04-16 2001-06-12 Pe Corporation (Ny) Apparatus and method for transferring small volumes of substances
FR2793261B1 (fr) 1999-05-05 2001-08-17 Genomic Procede et dispositif pour l'extraction d'adn, d'arn et de proteines a partir de prelevement biologiques
US6448090B1 (en) * 1999-07-09 2002-09-10 Orchid Biosciences, Inc. Fluid delivery system for a microfluidic device using alternating pressure waveforms
US6395232B1 (en) * 1999-07-09 2002-05-28 Orchid Biosciences, Inc. Fluid delivery system for a microfluidic device using a pressure pulse
US6429016B1 (en) 1999-10-01 2002-08-06 Isis Pharmaceuticals, Inc. System and method for sample positioning in a robotic system
EP1099483B1 (de) 1999-11-11 2009-02-11 Allegro Technologies Limited Abgabe von flüssigen Tropfen
WO2001057254A2 (en) 2000-02-02 2001-08-09 Cartesian Technologies, Inc. Method and apparatus for developing dna microarrays
US6932895B2 (en) 2000-02-15 2005-08-23 Large Scale Proteomics Corporation Automated electrophoresis gel manipulation apparatus
US7160511B2 (en) 2000-02-18 2007-01-09 Olympus Corporation Liquid pipetting apparatus and micro array manufacturing apparatus
US6387330B1 (en) * 2000-04-12 2002-05-14 George Steven Bova Method and apparatus for storing and dispensing reagents
US6431212B1 (en) 2000-05-24 2002-08-13 Jon W. Hayenga Valve for use in microfluidic structures
GB2380472A (en) 2000-06-05 2003-04-09 Nordson Corp Apparatus and methods for dispensing minute amounts of liquid
US6913879B1 (en) 2000-07-10 2005-07-05 Telechem International Inc. Microarray method of genotyping multiple samples at multiple LOCI
DE60132100T2 (de) 2000-08-30 2008-12-18 Biodot, Inc., Irvine Verfahren zur hochgeschwindigkeits-mikrofluidischen-dispergierung
US6852291B1 (en) 2000-10-11 2005-02-08 Innovadyne Technologies, Inc. Hybrid valve apparatus and method for fluid handling
EP1332000B1 (de) 2000-10-30 2012-06-20 Sequenom, Inc. Verfahren zur aufbringung von submikroliter fluid-volumina auf ein substrat
US6360794B1 (en) * 2000-12-19 2002-03-26 Bechtel Bwxt Idaho, Llc Apparatus and method for delivering a fluid to a container
JP2002228669A (ja) * 2001-01-31 2002-08-14 Shimadzu Corp 液体移送器及び反応容器
US6659142B2 (en) 2001-03-27 2003-12-09 Irm, Llc Apparatus and method for preparing fluid mixtures
CA2442978A1 (en) 2001-04-04 2002-10-17 Bioprocessors Corp. System and method for dispensing liquids
US6982063B2 (en) 2001-05-25 2006-01-03 Matrix Technologies Corp Automated pipetting system

Also Published As

Publication number Publication date
JP2007502986A (ja) 2007-02-15
US20050035143A1 (en) 2005-02-17
ATE453451T1 (de) 2010-01-15
EP1663494B1 (de) 2009-12-30
US7097070B2 (en) 2006-08-29
EP1663494A1 (de) 2006-06-07
WO2005016535A1 (en) 2005-02-24
DK1663494T3 (da) 2010-04-26

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