DE60143804D1 - Bioprothetischer füller und methoden, insbesondere für die bildung von bandscheibenbioprothesen in situ - Google Patents
Bioprothetischer füller und methoden, insbesondere für die bildung von bandscheibenbioprothesen in situInfo
- Publication number
- DE60143804D1 DE60143804D1 DE60143804T DE60143804T DE60143804D1 DE 60143804 D1 DE60143804 D1 DE 60143804D1 DE 60143804 T DE60143804 T DE 60143804T DE 60143804 T DE60143804 T DE 60143804T DE 60143804 D1 DE60143804 D1 DE 60143804D1
- Authority
- DE
- Germany
- Prior art keywords
- cavity
- biopolymer
- situ
- bioprosthetic
- proteinaceous
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 229920001222 biopolymer Polymers 0.000 abstract 4
- 239000007788 liquid Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 229920001744 Polyaldehyde Polymers 0.000 abstract 1
- 230000009969 flowable effect Effects 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
- A61L27/3645—Connective tissue
- A61L27/3654—Cartilage, e.g. meniscus
- A61L27/3658—Intervertebral discs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/442—Intervertebral or spinal discs, e.g. resilient
- A61F2002/4445—Means for culturing intervertebral disc tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/442—Intervertebral or spinal discs, e.g. resilient
- A61F2002/445—Intervertebral disc tissue harvest sites
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Transplantation (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Botany (AREA)
- Molecular Biology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Composite Materials (AREA)
- Materials Engineering (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24245700P | 2000-10-24 | 2000-10-24 | |
| PCT/US2001/032632 WO2002034111A2 (en) | 2000-10-24 | 2001-10-24 | In situ bioprosthetic filler and methods, particularly for the in situ formation of vertebral disc bioprosthetics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60143804D1 true DE60143804D1 (de) | 2011-02-17 |
Family
ID=22914850
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60143804T Expired - Lifetime DE60143804D1 (de) | 2000-10-24 | 2001-10-24 | Bioprothetischer füller und methoden, insbesondere für die bildung von bandscheibenbioprothesen in situ |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US20020049498A1 (de) |
| EP (1) | EP1328220B1 (de) |
| JP (1) | JP4202749B2 (de) |
| AT (1) | ATE494014T1 (de) |
| AU (2) | AU2002215387B2 (de) |
| CA (1) | CA2422884C (de) |
| DE (1) | DE60143804D1 (de) |
| ES (1) | ES2358498T3 (de) |
| WO (1) | WO2002034111A2 (de) |
Families Citing this family (102)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1230902A1 (de) | 1996-11-15 | 2002-08-14 | Advanced Bio Surfaces, Inc. | Biomateralsystem für in-situ Gewebewiederherstellung |
| JP2003530131A (ja) | 1999-03-07 | 2003-10-14 | ディスクレ リミテッド | コンピューターを利用する手術方法及び装置 |
| US6821276B2 (en) * | 1999-08-18 | 2004-11-23 | Intrinsic Therapeutics, Inc. | Intervertebral diagnostic and manipulation device |
| US20040044412A1 (en) * | 1999-08-18 | 2004-03-04 | Gregory Lambrecht | Devices and method for augmenting a vertebral disc |
| US7998213B2 (en) | 1999-08-18 | 2011-08-16 | Intrinsic Therapeutics, Inc. | Intervertebral disc herniation repair |
| US7507243B2 (en) * | 1999-08-18 | 2009-03-24 | Gregory Lambrecht | Devices and method for augmenting a vertebral disc |
| US7972337B2 (en) | 2005-12-28 | 2011-07-05 | Intrinsic Therapeutics, Inc. | Devices and methods for bone anchoring |
| US7258700B2 (en) | 1999-08-18 | 2007-08-21 | Intrinsic Therapeutics, Inc. | Devices and method for nucleus pulposus augmentation and retention |
| WO2009033100A1 (en) | 2007-09-07 | 2009-03-12 | Intrinsic Therapeutics, Inc. | Bone anchoring systems |
| US7553329B2 (en) | 1999-08-18 | 2009-06-30 | Intrinsic Therapeutics, Inc. | Stabilized intervertebral disc barrier |
| EP1624832A4 (de) | 1999-08-18 | 2008-12-24 | Intrinsic Therapeutics Inc | Vorrichtungen und verfahren zur augmentierung eines wirbelscheiben-nukleus |
| US8323341B2 (en) | 2007-09-07 | 2012-12-04 | Intrinsic Therapeutics, Inc. | Impaction grafting for vertebral fusion |
| US7717961B2 (en) | 1999-08-18 | 2010-05-18 | Intrinsic Therapeutics, Inc. | Apparatus delivery in an intervertebral disc |
| US7220281B2 (en) * | 1999-08-18 | 2007-05-22 | Intrinsic Therapeutics, Inc. | Implant for reinforcing and annulus fibrosis |
| US6805695B2 (en) | 2000-04-04 | 2004-10-19 | Spinalabs, Llc | Devices and methods for annular repair of intervertebral discs |
| US6723335B1 (en) | 2000-04-07 | 2004-04-20 | Jeffrey William Moehlenbruck | Methods and compositions for treating intervertebral disc degeneration |
| DE60143804D1 (de) * | 2000-10-24 | 2011-02-17 | Cryolife Inc | Bioprothetischer füller und methoden, insbesondere für die bildung von bandscheibenbioprothesen in situ |
| ES2662594T3 (es) * | 2000-11-07 | 2018-04-09 | Cryolife, Inc. | Biomateriales expandibles espumados y métodos. |
| EP1227094B1 (de) * | 2001-01-30 | 2005-12-14 | Nissan Chemical Industries Ltd. | Isocyanurate und Verfahren zu deren Herstellung |
| US7144393B2 (en) * | 2001-05-15 | 2006-12-05 | Dipoto Gene P | Structure for receiving surgical instruments |
| AU2002350026A1 (en) | 2001-11-01 | 2003-05-12 | Lawrence M. Boyd | System and method for the pretreatment of the endplates of an intervertebral disc |
| US6812211B2 (en) * | 2002-03-19 | 2004-11-02 | Michael Andrew Slivka | Method for nonsurgical treatment of the intervertebral disc and kit therefor |
| US20050209699A1 (en) * | 2002-03-19 | 2005-09-22 | Slivka Michael A | Method for nonsurgical treatment of the nucleus pulposus of the intervertebral disc using genipin or proanthrocyanidin, and kit therefor |
| US7001433B2 (en) | 2002-05-23 | 2006-02-21 | Pioneer Laboratories, Inc. | Artificial intervertebral disc device |
| US8388684B2 (en) | 2002-05-23 | 2013-03-05 | Pioneer Signal Technology, Inc. | Artificial disc device |
| US20040054414A1 (en) * | 2002-09-18 | 2004-03-18 | Trieu Hai H. | Collagen-based materials and methods for augmenting intervertebral discs |
| US7744651B2 (en) * | 2002-09-18 | 2010-06-29 | Warsaw Orthopedic, Inc | Compositions and methods for treating intervertebral discs with collagen-based materials |
| ES2343951T3 (es) * | 2002-09-24 | 2010-08-13 | Bogomir Gorensek | Dispositivo estabilizador para disco intervertebral y metodos para ello. |
| US6932843B2 (en) | 2002-09-25 | 2005-08-23 | Medicinelodge, Inc. | Apparatus and method for the in-situ formation of a structural prosthesis |
| NZ539779A (en) * | 2002-11-05 | 2009-01-31 | Spineology Inc | A semi-biological intervertebral disc replacement system created by inserting tissue promoting material into a cavity in the disc |
| CN100394989C (zh) * | 2002-11-15 | 2008-06-18 | 华沙整形外科股份有限公司 | 包含微粒状基于胶原材料的组合物的制药应用和包含所述组合物的滑膜关节 |
| US20040186471A1 (en) * | 2002-12-07 | 2004-09-23 | Sdgi Holdings, Inc. | Method and apparatus for intervertebral disc expansion |
| EP1594421A4 (de) * | 2003-01-17 | 2006-02-08 | Psinergi Corp | Künstlicher nucleus pulposus und verfahren zu dessen injektion |
| KR20050092795A (ko) * | 2003-01-31 | 2005-09-22 | 짐머 오르쏘바이올로직스 인코포레이티드 | 수핵 조직을 함유하는 하이드로젤 조성물 |
| FR2854801B1 (fr) * | 2003-05-12 | 2006-09-01 | Khorionyx | Implant injectable de globine insoluble |
| US20040260300A1 (en) * | 2003-06-20 | 2004-12-23 | Bogomir Gorensek | Method of delivering an implant through an annular defect in an intervertebral disc |
| ES2360907T3 (es) * | 2003-06-20 | 2011-06-10 | Intrinsic Therapeutics, Inc. | Dispositivo para administrar un implante a través de un defecto anular en un disco intervertebral. |
| US20050071012A1 (en) * | 2003-09-30 | 2005-03-31 | Hassan Serhan | Methods and devices to replace spinal disc nucleus pulposus |
| US7655012B2 (en) | 2003-10-02 | 2010-02-02 | Zimmer Spine, Inc. | Methods and apparatuses for minimally invasive replacement of intervertebral discs |
| US20050116400A1 (en) * | 2003-11-14 | 2005-06-02 | White Moreno J. | Non-linear fiber/matrix architecture |
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| US7235592B2 (en) | 2004-10-12 | 2007-06-26 | Zimmer Gmbh | PVA hydrogel |
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| US8197545B2 (en) * | 2005-10-27 | 2012-06-12 | Depuy Spine, Inc. | Nucleus augmentation delivery device and technique |
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| JP2007177244A (ja) | 2005-12-22 | 2007-07-12 | Zimmer Inc | ペルフルオロシクロブタン架橋ハイドロゲル |
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| US9408624B2 (en) | 2011-03-31 | 2016-08-09 | Isis Innovation Limited | Intervertebral disc treatment apparatus |
| US20120276008A1 (en) * | 2011-04-26 | 2012-11-01 | Spine Wave, Inc. | Radiopaque injectable nucleus hydrogel compositions |
| US9198769B2 (en) | 2011-12-23 | 2015-12-01 | Pioneer Surgical Technology, Inc. | Bone anchor assembly, bone plate system, and method |
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-
2001
- 2001-10-24 DE DE60143804T patent/DE60143804D1/de not_active Expired - Lifetime
- 2001-10-24 ES ES01984004T patent/ES2358498T3/es not_active Expired - Lifetime
- 2001-10-24 EP EP01984004A patent/EP1328220B1/de not_active Expired - Lifetime
- 2001-10-24 AT AT01984004T patent/ATE494014T1/de active
- 2001-10-24 AU AU2002215387A patent/AU2002215387B2/en not_active Ceased
- 2001-10-24 US US09/983,537 patent/US20020049498A1/en not_active Abandoned
- 2001-10-24 JP JP2002537171A patent/JP4202749B2/ja not_active Expired - Fee Related
- 2001-10-24 CA CA002422884A patent/CA2422884C/en not_active Expired - Fee Related
- 2001-10-24 AU AU1538702A patent/AU1538702A/xx active Pending
- 2001-10-24 WO PCT/US2001/032632 patent/WO2002034111A2/en not_active Ceased
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2004
- 2004-12-10 US US11/008,609 patent/US7621959B2/en not_active Expired - Fee Related
-
2006
- 2006-12-08 US US11/635,928 patent/US7621954B2/en not_active Expired - Fee Related
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2007
- 2007-10-31 US US11/932,066 patent/US7896920B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
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| US20070093902A1 (en) | 2007-04-26 |
| ES2358498T3 (es) | 2011-05-11 |
| US20050102030A1 (en) | 2005-05-12 |
| EP1328220B1 (de) | 2011-01-05 |
| US7896920B2 (en) | 2011-03-01 |
| US20020049498A1 (en) | 2002-04-25 |
| AU1538702A (en) | 2002-05-06 |
| US20080058942A1 (en) | 2008-03-06 |
| CA2422884C (en) | 2009-05-19 |
| JP2004532656A (ja) | 2004-10-28 |
| WO2002034111A3 (en) | 2003-01-16 |
| US7621959B2 (en) | 2009-11-24 |
| EP1328220A4 (de) | 2009-08-19 |
| US7621954B2 (en) | 2009-11-24 |
| EP1328220A2 (de) | 2003-07-23 |
| JP4202749B2 (ja) | 2008-12-24 |
| WO2002034111A2 (en) | 2002-05-02 |
| CA2422884A1 (en) | 2002-05-02 |
| ATE494014T1 (de) | 2011-01-15 |
| AU2002215387B2 (en) | 2005-09-29 |
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