DE60138760D1 - Phosphonocephem-verbindung - Google Patents

Phosphonocephem-verbindung

Info

Publication number: DE60138760D1
Authority: DE; Germany
Prior art keywords: phosphonocephem; connection; formula; compound represented; disodium salt
Prior art date: 2000-08-10
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE60138760T

Other languages

English (en)

Inventor

Tomoyasu Ishikawa

Shohei Hashiguchi

Yuji Iizawa

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Takeda Pharmaceutical Co Ltd

Original Assignee

Takeda Pharmaceutical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-08-10

Filing date

2001-08-10

Publication date

2009-07-02

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26598061&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60138760(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2001-08-10 Application filed by Takeda Pharmaceutical Co Ltd filed Critical Takeda Pharmaceutical Co Ltd

2009-07-02 Application granted granted Critical

2009-07-02 Publication of DE60138760D1 publication Critical patent/DE60138760D1/de

2021-08-11 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- C07F9/65613—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system (X = CH2, O, S, NH) optionally with an additional double bond and/or substituents, e.g. cephalosporins and analogs

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cephalosporin Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

DE60138760T 2000-08-10 2001-08-10 Phosphonocephem-verbindung Expired - Lifetime DE60138760D1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP2000247966		2000-08-10
JP2000354959		2000-11-21
PCT/JP2001/006904 WO2002014333A1 (en)	2000-08-10	2001-08-10	Phosphonocephem compound

Publications (1)

Publication Number	Publication Date
DE60138760D1 true DE60138760D1 (de)	2009-07-02

Family

ID=26598061

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE60138760T Expired - Lifetime DE60138760D1 (de)	2000-08-10	2001-08-10	Phosphonocephem-verbindung

Country Status (13)

Country	Link
US (2)	US6906055B2 (de)
EP (2)	EP2020416A1 (de)
KR (1)	KR100826487B1 (de)
CN (1)	CN1189471C (de)
AT (1)	ATE431827T1 (de)
AU (1)	AU2001277753A1 (de)
CA (1)	CA2418614C (de)
CY (1)	CY1109313T1 (de)
DE (1)	DE60138760D1 (de)
DK (1)	DK1310502T3 (de)
ES (1)	ES2323759T3 (de)
PT (1)	PT1310502E (de)
WO (1)	WO2002014333A1 (de)

Families Citing this family (34)

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Publication number	Priority date	Publication date	Assignee	Title
CN1189471C (zh) *	2000-08-10	2005-02-16	武田药品工业株式会社	膦酰基头孢烯化合物
AT501931B1 (de) *	2004-12-10	2007-08-15	Chemiefaser Lenzing Ag	Cellulosestapelfaser und ihre verwendung
US20070238719A1 (en) *	2005-05-10	2007-10-11	Hopkins Scott J	Method for reducing the risk of or preventing infection due to surgical or invasive medical procedures
US20070249577A1 (en) *	2005-05-10	2007-10-25	Hopkins Scott J	Method for reducing the risk of or preventing infection due to surgical or invasive medical procedures
US20070238720A1 (en) *	2005-05-10	2007-10-11	Hopkins Scott J	Method for reducing the risk of or preventing infection due to surgical or invasive medical procedures
CN101868240A (zh) *	2007-09-21	2010-10-20	阿斯利康(瑞典)有限公司	适合肠胃外给药的包含头孢烯衍生物的可溶剂型
US20100197650A1 (en) *	2008-08-28	2010-08-05	Forest Laboratories Holdings Ltd.	Compositions and methods of treatment comprising ceftaroline
CA2753387C (en) *	2009-02-23	2017-01-24	Forest Laboratories Holdings Limited	Novel cephem compounds useful for the treatment of bacterial infections
AU2010295269B2 (en) *	2009-09-21	2014-06-05	Pfizer Anti-Infectives Ab	Compositions and methods for treating bacterial infections using ceftaroline
FR2951171A1 (fr)	2009-10-09	2011-04-15	Novexel	Nouveau sel de sodium d'un compose azabicyclique sous forme enantiomere cristallisee et nouvelles formes polymorphes et pseudopolymorphes ainsi que leur preparation
WO2012172368A1 (en)	2011-06-17	2012-12-20	Astrazeneca Ab	Process for preparing heterocyclic compounds including trans-7-oxo-6-(sulphooxy)-1,6-diazabicyclo[3,2,1]octane-2-carboxamide and salts thereof
PT2753620T (pt)	2011-09-09	2017-05-26	Sandoz Ag	Novo processo para a preparação de ceftarolina fosamil
US20140350240A1 (en)	2011-12-07	2014-11-27	Ranbaxy Laboratories Limited	Process for preparing ceftaroline salts or hydrates thereof
USRE47787E1 (en) *	2012-10-19	2019-12-31	Sandoz Ag	Process for preparing ceftaroline fosamil
CN102977124B (zh) *	2012-12-13	2014-11-26	山东诚创医药技术开发有限公司	7β-[(苯乙酰)氨基]-3-[4-(1-甲基-4-吡啶鎓)-2-噻唑硫基]-3-头孢烯-4-羧酸二苯甲基酯的制备方法
US9534004B2 (en) *	2012-12-20	2017-01-03	Sandoz Ag	Crystalline forms of ceftaroline fosamil
JP6671303B2 (ja)	2014-02-21	2020-03-25	ミクウルクファーマシューティカルズ，インコーポレイテッド	治療的投与のための水溶性ｏ−カルボニルホスホルアミダートプロドラッグ
WO2016008393A1 (zh) *	2014-07-14	2016-01-21	正大天晴药业集团股份有限公司	头孢罗膦氨基酸盐及其结晶
CN104177408B (zh) *	2014-09-12	2016-09-07	衡水衡林生物科技有限公司	（z）-2-(5-二氯磷酰氨基-1,2,4-噻二唑-3-基)-2-乙氧亚胺基乙酰氯的制备方法
WO2016066631A1 (en)	2014-10-28	2016-05-06	Sandoz Ag	Pharmaceutical composition consisting of ceftaroline fosamil acetic acid solvate particles and arginine particles, both having a specific particle size distribution
WO2016128580A1 (en) *	2015-02-13	2016-08-18	Fresenius Kabi Anti-Infectives Srl	Cephalosporin intermediate and process for its preparation
CN104725425B (zh) *	2015-04-09	2017-01-04	山东罗欣药业集团股份有限公司	一种头孢洛林酯的制备方法
CN104892674B (zh) *	2015-06-18	2017-01-18	河北大学	一种头孢洛林酯的制备方法
CN107216353B (zh) *	2016-03-21	2020-05-19	山东诚创医药技术开发有限公司	一种头孢洛林酯咪唑盐的精制方法
CN106565784B (zh) *	2016-10-31	2019-02-26	瑞阳制药有限公司	头孢洛林酯二钠盐的纯化方法
CN106749410B (zh) *	2016-12-02	2018-06-12	齐鲁安替制药有限公司	一种高收率头孢洛林酯的制备方法
CN107325114B (zh) *	2017-07-04	2019-06-11	吉林省爱诺德生物工程有限公司	一种头孢洛林酯中间体的制备方法
CN108440566A (zh) *	2018-01-04	2018-08-24	北京满格医药科技有限公司	一种头孢洛林酯中间体1的精制方法
CN110872322B (zh) *	2018-08-29	2022-08-02	上海博志研新药物技术有限公司	乙酸头孢罗膦一水合物及其中间体的制备方法
KR102205496B1 (ko) *	2019-02-27	2021-01-21	국제약품(주)	세팔로스포린 화합물 제조용 중간체의 제조방법 및 그로부터 제조된 세프타롤린 포사밀 금속염
CN113214323A (zh) *	2021-04-30	2021-08-06	瑞阳制药股份有限公司	分段式头孢罗膦高效稳定析晶方法
CN113336775A (zh) *	2021-06-21	2021-09-03	湖北凌晟药业有限公司	一种头孢维星中间体的合成方法
CN115417886B (zh) *	2022-09-19	2024-06-14	瑞阳制药股份有限公司	头孢类医药中间体的高效制备方法
CN120098038A (zh) *	2025-05-07	2025-06-06	广东立国制药有限公司	一种头孢洛林酯的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4142059A (en) *	1976-04-02	1979-02-27	Eli Lilly And Company	Spray drying sodium and potassium 2-ethylhexanoate
US5948774A (en) *	1995-05-29	1999-09-07	Takeda Chemical Industries, Ltd.	Cephem compounds, their production and use
JP3927262B2 (ja)	1995-07-19	2007-06-06	武田薬品工業株式会社	セフェム化合物、その製造法および抗菌組成物
TW473479B (en) *	1997-12-19	2002-01-21	Takeda Chemical Industries Ltd	Phosphonocephem derivatives, their production and use
JP2000247966A (ja)	1999-03-01	2000-09-12	Wakunaga Pharmaceut Co Ltd	２，６−ジアルキル−γ―ピロン誘導体の製造法及びその製造中間体
US6050882A (en)	1999-06-10	2000-04-18	Applied Materials, Inc.	Carrier head to apply pressure to and retain a substrate
CN1189471C (zh) *	2000-08-10	2005-02-16	武田药品工业株式会社	膦酰基头孢烯化合物

2001
- 2001-08-10 CN CNB018160956A patent/CN1189471C/zh not_active Expired - Lifetime
- 2001-08-10 KR KR1020037001957A patent/KR100826487B1/ko not_active Expired - Lifetime
- 2001-08-10 DE DE60138760T patent/DE60138760D1/de not_active Expired - Lifetime
- 2001-08-10 AT AT01955659T patent/ATE431827T1/de active
- 2001-08-10 US US10/343,285 patent/US6906055B2/en not_active Expired - Lifetime
- 2001-08-10 DK DK01955659T patent/DK1310502T3/da active
- 2001-08-10 EP EP08075636A patent/EP2020416A1/de not_active Withdrawn
- 2001-08-10 EP EP01955659A patent/EP1310502B1/de not_active Expired - Lifetime
- 2001-08-10 CA CA002418614A patent/CA2418614C/en not_active Expired - Lifetime
- 2001-08-10 AU AU2001277753A patent/AU2001277753A1/en not_active Abandoned
- 2001-08-10 WO PCT/JP2001/006904 patent/WO2002014333A1/ja not_active Ceased
- 2001-08-10 PT PT01955659T patent/PT1310502E/pt unknown
- 2001-08-10 ES ES01955659T patent/ES2323759T3/es not_active Expired - Lifetime
2005
- 2005-02-23 US US11/063,715 patent/US7419973B2/en not_active Expired - Lifetime
2009
- 2009-08-12 CY CY20091100867T patent/CY1109313T1/el unknown

Also Published As

Publication number	Publication date
EP1310502A1 (de)	2003-05-14
CN1462275A (zh)	2003-12-17
EP1310502B1 (de)	2009-05-20
PT1310502E (pt)	2009-07-31
CA2418614A1 (en)	2003-02-04
US6906055B2 (en)	2005-06-14
ES2323759T3 (es)	2009-07-24
DK1310502T3 (da)	2009-09-07
WO2002014333A1 (en)	2002-02-21
US20050176697A1 (en)	2005-08-11
KR100826487B1 (ko)	2008-05-02
AU2001277753A1 (en)	2002-02-25
EP2020416A1 (de)	2009-02-04
US20040023943A1 (en)	2004-02-05
CA2418614C (en)	2008-06-10
ATE431827T1 (de)	2009-06-15
EP1310502A4 (de)	2007-08-01
US7419973B2 (en)	2008-09-02
CY1109313T1 (el)	2014-07-02
KR20030022891A (ko)	2003-03-17
CN1189471C (zh)	2005-02-16

Publication	Publication Date	Title
DE60138760D1 (de)	2009-07-02	Phosphonocephem-verbindung
CY1113657T1 (el)	2016-06-22	Νεα παραγωγα βενζοφαινονης ή αλατα αυτων
DE60229736D1 (de)	2008-12-18	Spiroinden- und spiroindan-verbindungen
CY1113578T1 (el)	2016-06-22	2,3-διυδρο-6-νιτροϊμιδαζο 2,1 -b-οξαζολια
CY1108738T1 (el)	2014-07-02	Θεραπευτικοι παραγοντες χρησιμοι για την αγωγη του πονου
CY1114008T1 (el)	2016-07-27	Θειενοπυριμιδινικες ενωσεις και χρηση τους
ATE491703T1 (de)	2011-01-15	Phthalazinonderivate
SE0000540D0 (sv)	2000-02-18	New compounds
DOP2001000151A (es)	2002-05-15	Derivados de imidazopirimidina y derivados de triazolopimidina.
SE0100902D0 (sv)	2001-03-15	Compounds
CY1106247T1 (el)	2011-06-08	Θειοφαινο- και θειαζολοσουλφοναμιδες ως αντινεοπλαστικοι παραγοντες
IT1311922B1 (it)	2002-03-20	Composti farmaceutici.
ATE198739T1 (de)	2001-02-15	2,3-diaminopropionsäurederivate
CR6574A (es)	2004-10-28	Sales de avermectinas substituidas en la posicion 4 con propiedades plaguicidas
ID24846A (id)	2000-08-24	Turunan-turunan bifenilamidina
DOP2002000371A (es)	2002-10-15	Fenil-heterociclil-eteres
DE60223904D1 (de)	2008-01-17	Benzylaminanalogen
DE60125378D1 (de)	2007-02-01	Verfahren zur herstellung von 2-aminomethyl-halogen-pyridinen
DE60039695D1 (de)	2008-09-11	Antifucoidan antikörper
DK1085019T3 (da)	2003-05-26	Omoprazolsyntese
HN1999000038A (es)	2000-03-14	Nuevos compuestos fungicidas
EP1557407A4 (de)	2006-11-15	Neue alpha-ketoamidderivate und deren verwendung
DK1311518T3 (da)	2006-02-13	Fremstilling af N-beskyttede-3-pyrroliden-lactam-substituerede phosphoniumsalte
DK0645374T3 (da)	1996-12-23	5-Amino-2-phenoxylsulfonanilidforbindelse
UY26778A1 (es)	2002-01-31	Derivados de ácido heteroarilalcanoico.

Legal Events

Date	Code	Title	Description
2010-06-10	8364	No opposition during term of opposition