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DE60134265D1 - Herstellung grosser liposome durch infusion in peg - Google Patents

Herstellung grosser liposome durch infusion in peg

Info

Publication number
DE60134265D1
DE60134265D1 DE60134265T DE60134265T DE60134265D1 DE 60134265 D1 DE60134265 D1 DE 60134265D1 DE 60134265 T DE60134265 T DE 60134265T DE 60134265 T DE60134265 T DE 60134265T DE 60134265 D1 DE60134265 D1 DE 60134265D1
Authority
DE
Germany
Prior art keywords
polymer
liposome
lipid
infusion
peg
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60134265T
Other languages
English (en)
Inventor
Lawrence Boni
Fangjun Wu
Roy Fennimore
Michael M Batenjany
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oncothyreon Canada Inc
Original Assignee
Biomira Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomira Inc filed Critical Biomira Inc
Application granted granted Critical
Publication of DE60134265D1 publication Critical patent/DE60134265D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001169—Tumor associated carbohydrates
    • A61K39/00117—Mucins, e.g. MUC-1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
DE60134265T 2000-12-01 2001-12-03 Herstellung grosser liposome durch infusion in peg Expired - Fee Related DE60134265D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25012400P 2000-12-01 2000-12-01
PCT/US2001/045142 WO2002043699A2 (en) 2000-12-01 2001-12-03 Preparation of large liposomes by infusion into peg

Publications (1)

Publication Number Publication Date
DE60134265D1 true DE60134265D1 (de) 2008-07-10

Family

ID=22946382

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60134265T Expired - Fee Related DE60134265D1 (de) 2000-12-01 2001-12-03 Herstellung grosser liposome durch infusion in peg

Country Status (8)

Country Link
US (1) US20020160039A1 (de)
EP (1) EP1343476B1 (de)
JP (1) JP2004522717A (de)
AT (1) ATE396707T1 (de)
AU (2) AU2002219998B2 (de)
CA (1) CA2436348A1 (de)
DE (1) DE60134265D1 (de)
WO (1) WO2002043699A2 (de)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1377275B1 (de) 2001-03-27 2006-10-25 Biomira, Inc. Impfstoff zur modulation zwischen t1 und t2 immunantworten
US20040082521A1 (en) * 2002-03-29 2004-04-29 Azaya Therapeutics Inc. Novel formulations of digitalis glycosides for treating cell-proliferative and other diseases
ATE485031T1 (de) 2002-06-28 2010-11-15 Protiva Biotherapeutics Inc Verfahren und vorrichtung zur herstellung von liposomen
US7718189B2 (en) 2002-10-29 2010-05-18 Transave, Inc. Sustained release of antiinfectives
CA2505520C (en) * 2002-11-06 2012-07-17 Azaya Therapeutics, Inc. Protein-stabilized liposomal formulations of pharmaceutical agents
TW201204410A (en) * 2004-04-01 2012-02-01 Oncothyreon Inc Mucinous glycoprotein (MUC-1) vaccine
TW201615208A (zh) 2005-06-28 2016-05-01 安柯席爾伊恩股份有限公司 以黏液性糖蛋白（ｍｕｃ-１）疫苗治療病人之方法
EP1937213B1 (de) 2005-07-27 2017-10-25 Protiva Biotherapeutics Inc. Systeme und verfahren zur herstellung von liposomen
CA2523032A1 (en) 2005-10-07 2007-04-07 Immunovaccine Technologies Inc. Vaccines for cancer therapy
EP3067046B1 (de) 2005-12-08 2020-03-25 Insmed Incorporated Antiinfektive zusammensetzungen auf lipidbasis zur behandlung von lungeninfekten
WO2007079448A2 (en) 2006-01-03 2007-07-12 University Of Georgia Research Foundation, Inc. Three component carbohydrate vaccine
WO2010002478A2 (en) 2008-07-03 2010-01-07 University Of Georgia Research Foundation, Inc. Glycopeptide and uses thereof
WO2008137717A1 (en) 2007-05-04 2008-11-13 Transave, Inc. Compositions of multicationic drugs for reducing interactions with polyanionic biomolecules and methods and uses thereof
US9119783B2 (en) 2007-05-07 2015-09-01 Insmed Incorporated Method of treating pulmonary disorders with liposomal amikacin formulations
US9333214B2 (en) 2007-05-07 2016-05-10 Insmed Incorporated Method for treating pulmonary disorders with liposomal amikacin formulations
US9114081B2 (en) 2007-05-07 2015-08-25 Insmed Incorporated Methods of treating pulmonary disorders with liposomal amikacin formulations
AU2008303023B2 (en) 2007-09-27 2014-01-09 Immunovaccine Technologies Inc. Use of liposomes in a carrier comprising a continuous hydrophobic phase for delivery of polynucleotides in vivo
CN102056622B (zh) 2008-06-05 2016-04-06 免疫疫苗技术有限公司 包含脂质体、抗原、多核苷酸和含疏水物质的连续相的载体的组合物
JP5808107B2 (ja) * 2008-12-17 2015-11-10 学校法人慶應義塾 細胞特異的能動集積性を有する光線力学療法剤
CA2747182C (en) * 2008-12-17 2014-11-18 Robert A. Dupuit Method of making small liposomes
CA2735968A1 (en) * 2008-12-24 2010-07-01 Biomedcore Inc. Method for producing liposome and method for dissolving cholesterol
JP5771366B2 (ja) 2009-09-02 2015-08-26 株式会社バイオメッドコア リポソーム製造装置及び方法
JP4829351B2 (ja) * 2010-02-05 2011-12-07 ナノキャリア株式会社 易崩壊型ポリマーミセル組成物
BR112013021779A2 (pt) 2011-02-24 2017-09-19 Oncothyreon Inc vacina de glicolipopeptídeo baseada em muc1 com adjuvante.
EP2763698B1 (de) 2011-10-06 2020-12-02 ImmunoVaccine Technologies Inc. Liposomzusammensetzungen mit einem adjuvans zur aktivierung oder steigerung der aktivität von tlr2 und verwendungen davon
JP6207007B2 (ja) * 2012-05-15 2017-10-04 国立大学法人 千葉大学 リポソームおよびその作製方法
EP4331675A3 (de) 2012-05-21 2024-05-29 Insmed Incorporated Systeme zur behandlung von lungeninfektionen
US10124066B2 (en) 2012-11-29 2018-11-13 Insmed Incorporated Stabilized vancomycin formulations
CN106535877A (zh) 2014-05-15 2017-03-22 英斯梅德股份有限公司 用于治疗肺部非结核性分枝杆菌感染的方法
US12491261B2 (en) 2016-10-26 2025-12-09 Acuitas Therapeutics, Inc. Lipid nanoparticle formulations
WO2019191627A1 (en) 2018-03-30 2019-10-03 Insmed Incorporated Methods for continuous manufacture of liposomal drug products
AU2021308681A1 (en) 2020-07-16 2023-03-09 Acuitas Therapeutics, Inc. Cationic lipids for use in lipid nanoparticles
KR20240123832A (ko) 2021-12-16 2024-08-14 아퀴타스 테라퓨틱스 인크. 지질 나노입자 제형에 사용하기 위한 지질

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH621479A5 (de) * 1977-08-05 1981-02-13 Battelle Memorial Institute
US4880635B1 (en) * 1984-08-08 1996-07-02 Liposome Company Dehydrated liposomes
ES2087151T3 (es) * 1989-03-31 1996-07-16 Univ California Preparacion de composiciones complejas de liposomas y lipidos.
CA2318556A1 (en) * 1998-01-16 1999-07-22 Biomira, Inc. Lipomatrix preparation

Also Published As

Publication number Publication date
CA2436348A1 (en) 2002-06-06
ATE396707T1 (de) 2008-06-15
WO2002043699A3 (en) 2002-10-17
US20020160039A1 (en) 2002-10-31
JP2004522717A (ja) 2004-07-29
EP1343476A2 (de) 2003-09-17
AU2002219998B2 (en) 2006-03-02
AU1999802A (en) 2002-06-11
EP1343476B1 (de) 2008-05-28
WO2002043699A2 (en) 2002-06-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee