DE60134656D1 - Hilfsmittel und methoden zur transdermalen applikation von felodipin - Google Patents
Hilfsmittel und methoden zur transdermalen applikation von felodipinInfo
- Publication number
- DE60134656D1 DE60134656D1 DE60134656T DE60134656T DE60134656D1 DE 60134656 D1 DE60134656 D1 DE 60134656D1 DE 60134656 T DE60134656 T DE 60134656T DE 60134656 T DE60134656 T DE 60134656T DE 60134656 D1 DE60134656 D1 DE 60134656D1
- Authority
- DE
- Germany
- Prior art keywords
- felodipin
- additives
- methods
- transdermal application
- skin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000000654 additive Substances 0.000 title 1
- 238000009472 formulation Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- RZTAMFZIAATZDJ-HNNXBMFYSA-N 5-o-ethyl 3-o-methyl (4s)-4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate Chemical compound CCOC(=O)C1=C(C)NC(C)=C(C(=O)OC)[C@@H]1C1=CC=CC(Cl)=C1Cl RZTAMFZIAATZDJ-HNNXBMFYSA-N 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 229960003580 felodipine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24251400P | 2000-10-23 | 2000-10-23 | |
| PCT/US2001/049950 WO2002034206A2 (en) | 2000-10-23 | 2001-10-23 | Felodipine transdermal device and methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60134656D1 true DE60134656D1 (de) | 2008-08-14 |
Family
ID=22915068
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60134656T Expired - Lifetime DE60134656D1 (de) | 2000-10-23 | 2001-10-23 | Hilfsmittel und methoden zur transdermalen applikation von felodipin |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1328273B1 (de) |
| AT (1) | ATE399551T1 (de) |
| AU (1) | AU2002232755A1 (de) |
| CY (1) | CY1108368T1 (de) |
| DE (1) | DE60134656D1 (de) |
| DK (1) | DK1328273T3 (de) |
| ES (1) | ES2309107T3 (de) |
| PT (1) | PT1328273E (de) |
| WO (1) | WO2002034206A2 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10305137A1 (de) * | 2003-02-07 | 2004-08-26 | Novosis Ag | Transdermale therapeutische Abgabesysteme mit einem Butenolid |
| DE602005015679D1 (de) * | 2004-01-14 | 2009-09-10 | Lavipharm Lab Inc | Transdermale abgabevorrichtung für dihydropyridin-artige calcium-antagonisten mit 2 fettsäuren |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0661971A1 (de) * | 1991-12-02 | 1995-07-12 | Sepracor, Inc. | Verfahren und zusammensetzungen zur behandlung von hypertonie, angina und anderen erkrankungen unter verwendung von optisch reinem s(-) felodipin |
| US5882676A (en) * | 1995-05-26 | 1999-03-16 | Alza Corporation | Skin permeation enhancer compositions using acyl lactylates |
| US5968547A (en) * | 1997-02-24 | 1999-10-19 | Euro-Celtique, S.A. | Method of providing sustained analgesia with buprenorphine |
| AU2978400A (en) * | 1999-02-02 | 2000-08-25 | Ortho-Mcneil Pharmaceutical, Inc. | Method of manufacture for transdermal matrices |
-
2001
- 2001-10-23 PT PT01988573T patent/PT1328273E/pt unknown
- 2001-10-23 AU AU2002232755A patent/AU2002232755A1/en not_active Abandoned
- 2001-10-23 AT AT01988573T patent/ATE399551T1/de not_active IP Right Cessation
- 2001-10-23 WO PCT/US2001/049950 patent/WO2002034206A2/en not_active Ceased
- 2001-10-23 EP EP01988573A patent/EP1328273B1/de not_active Expired - Lifetime
- 2001-10-23 DE DE60134656T patent/DE60134656D1/de not_active Expired - Lifetime
- 2001-10-23 ES ES01988573T patent/ES2309107T3/es not_active Expired - Lifetime
- 2001-10-23 DK DK01988573T patent/DK1328273T3/da active
-
2008
- 2008-09-24 CY CY20081101041T patent/CY1108368T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1328273B1 (de) | 2008-07-02 |
| WO2002034206A9 (en) | 2003-04-17 |
| ATE399551T1 (de) | 2008-07-15 |
| EP1328273A2 (de) | 2003-07-23 |
| WO2002034206A2 (en) | 2002-05-02 |
| PT1328273E (pt) | 2008-09-23 |
| EP1328273A4 (de) | 2004-09-22 |
| ES2309107T3 (es) | 2008-12-16 |
| CY1108368T1 (el) | 2014-02-12 |
| AU2002232755A1 (en) | 2002-05-06 |
| WO2002034206A3 (en) | 2002-07-18 |
| DK1328273T3 (da) | 2008-10-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |