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DE60133674D1 - Zwischenprodukte für die herstellung von mirtazapin und verfahren zu deren herstellung - Google Patents

Zwischenprodukte für die herstellung von mirtazapin und verfahren zu deren herstellung

Info

Publication number
DE60133674D1
DE60133674D1 DE60133674T DE60133674T DE60133674D1 DE 60133674 D1 DE60133674 D1 DE 60133674D1 DE 60133674 T DE60133674 T DE 60133674T DE 60133674 T DE60133674 T DE 60133674T DE 60133674 D1 DE60133674 D1 DE 60133674D1
Authority
DE
Germany
Prior art keywords
obtaining
mirtazapin
manufacture
production
intermediate products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60133674T
Other languages
English (en)
Inventor
I Llado Jordi Bosch
Garcia Pelayo Camps
Lascorz Juan Contreras
Miguel Ma Carmen Onrubia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medichem SA
Original Assignee
Medichem SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medichem SA filed Critical Medichem SA
Application granted granted Critical
Publication of DE60133674D1 publication Critical patent/DE60133674D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE60133674T 2001-09-14 2001-09-14 Zwischenprodukte für die herstellung von mirtazapin und verfahren zu deren herstellung Expired - Lifetime DE60133674D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/ES2001/000347 WO2003024918A1 (es) 2001-09-14 2001-09-14 Compuestos intermedios para la preparación de mirtazapina y sus procedimientos de obtención

Publications (1)

Publication Number Publication Date
DE60133674D1 true DE60133674D1 (de) 2008-05-29

Family

ID=8244377

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60133674T Expired - Lifetime DE60133674D1 (de) 2001-09-14 2001-09-14 Zwischenprodukte für die herstellung von mirtazapin und verfahren zu deren herstellung

Country Status (8)

Country Link
US (1) US7265223B2 (de)
EP (1) EP1426356B1 (de)
AT (1) ATE392410T1 (de)
CA (1) CA2460571A1 (de)
DE (1) DE60133674D1 (de)
HU (1) HUP0401921A3 (de)
IL (1) IL160694A0 (de)
WO (1) WO2003024918A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7041826B2 (en) * 2003-06-02 2006-05-09 Aurobindo Pharma Ltd. Process for preparing 1-methyl-3-phenylpiperazine using a novel intermediate
TW200815370A (en) * 2006-06-16 2008-04-01 Organon Nv Stereoselective synthesis of (S)-1-methyl-3-phenylpiperazine
MX2009010967A (es) 2007-04-11 2009-12-15 Organon Nv Un metodo para la preparacion de mirtazapina.
CN112094241B (zh) * 2020-09-19 2023-04-18 浙江凯普化工有限公司 一种1,4-二氮杂螺[5,5]十一烷-3-酮的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3102068A (en) * 1961-10-10 1963-08-27 Michigan State University Of A Method of controlling bacterial diseases of fruit trees
US5378729A (en) * 1985-02-15 1995-01-03 Research Corporation Technologies, Inc. Amino acid derivative anticonvulsant
FR2585702B1 (fr) 1985-07-31 1989-03-03 Lafon Labor Derives de phenyl-piperazine, procede de preparation et utilisation en therapeutique
GB9305175D0 (en) * 1993-03-13 1993-04-28 Smithkline Beecham Plc Novel process
IL146024A0 (en) 1999-04-19 2002-07-25 Teva Pharma Novel synthesis of piperazine ring

Also Published As

Publication number Publication date
US7265223B2 (en) 2007-09-04
HUP0401921A3 (en) 2008-03-28
IL160694A0 (en) 2004-08-31
EP1426356B1 (de) 2008-04-16
HUP0401921A2 (hu) 2005-01-28
ATE392410T1 (de) 2008-05-15
US20040236107A1 (en) 2004-11-25
CA2460571A1 (en) 2003-03-27
WO2003024918A1 (es) 2003-03-27
EP1426356A1 (de) 2004-06-09

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Legal Events

Date Code Title Description
8332 No legal effect for de