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DE60132094D1 - Verfahren zur Herstellung von gereinigten Partikeln - Google Patents

Verfahren zur Herstellung von gereinigten Partikeln

Info

Publication number
DE60132094D1
DE60132094D1 DE60132094T DE60132094T DE60132094D1 DE 60132094 D1 DE60132094 D1 DE 60132094D1 DE 60132094 T DE60132094 T DE 60132094T DE 60132094 T DE60132094 T DE 60132094T DE 60132094 D1 DE60132094 D1 DE 60132094D1
Authority
DE
Germany
Prior art keywords
microparticles
preparation
purified particles
carry
purifying
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60132094T
Other languages
English (en)
Other versions
DE60132094T2 (de
DE60132094T3 (de
Inventor
Buitenen Adrianus Francisc Van
Rudolf Verrijk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Octoplus Polyactive Sciences Bv Leiden Nl
Original Assignee
OctoPlus Technologies BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8181147&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60132094(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by OctoPlus Technologies BV filed Critical OctoPlus Technologies BV
Priority to DE60132094T priority Critical patent/DE60132094T3/de
Publication of DE60132094D1 publication Critical patent/DE60132094D1/de
Publication of DE60132094T2 publication Critical patent/DE60132094T2/de
Application granted granted Critical
Publication of DE60132094T3 publication Critical patent/DE60132094T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/145—Ultrafiltration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/16—Feed pretreatment
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/10—Complex coacervation, i.e. interaction of oppositely charged particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/12—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/14—Polymerisation; cross-linking
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/18—Stationary reactors having moving elements inside
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2311/00—Details relating to membrane separation process operations and control
    • B01D2311/04—Specific process operations in the feed stream; Feed pretreatment
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2311/00—Details relating to membrane separation process operations and control
    • B01D2311/08—Specific process operations in the concentrate stream
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00002—Chemical plants
    • B01J2219/00004—Scale aspects
    • B01J2219/00006—Large-scale industrial plants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00002—Chemical plants
    • B01J2219/00027—Process aspects
    • B01J2219/00033—Continuous processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00002—Chemical plants
    • B01J2219/00027—Process aspects
    • B01J2219/0004—Processes in series

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE60132094T 2001-10-26 2001-10-26 Verfahren zur Herstellung von gereinigten Partikeln Expired - Lifetime DE60132094T3 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE60132094T DE60132094T3 (de) 2001-10-26 2001-10-26 Verfahren zur Herstellung von gereinigten Partikeln

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE60132094T DE60132094T3 (de) 2001-10-26 2001-10-26 Verfahren zur Herstellung von gereinigten Partikeln
EP01204096A EP1306127B2 (de) 2001-10-26 2001-10-26 Verfahren zur Herstellung von gereinigten Partikeln

Publications (3)

Publication Number Publication Date
DE60132094D1 true DE60132094D1 (de) 2008-02-07
DE60132094T2 DE60132094T2 (de) 2008-12-11
DE60132094T3 DE60132094T3 (de) 2012-02-02

Family

ID=8181147

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60132094T Expired - Lifetime DE60132094T3 (de) 2001-10-26 2001-10-26 Verfahren zur Herstellung von gereinigten Partikeln

Country Status (6)

Country Link
US (1) US7468151B2 (de)
EP (2) EP1306127B2 (de)
AT (1) ATE381963T1 (de)
CA (1) CA2464668C (de)
DE (1) DE60132094T3 (de)
WO (1) WO2003035244A1 (de)

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DE10205362A1 (de) * 2002-02-08 2003-08-21 Abbott Gmbh & Co Kg Verfahren zur Herstellung wasserdispergierbarer Trockenpulver von in Wasser schwer löslichen Verbindungen
EP1595534A1 (de) 2004-05-13 2005-11-16 Universiteit Utrecht Holding B.V. Gelzusammensetzung enthaltend geladenepolymere
EP2034954B1 (de) 2006-03-30 2019-02-20 Engene, Inc. Nicht virale zusammensetzungen und verfahren zur in-vivo-transfektion von darmzellen
WO2008003043A2 (en) * 2006-06-28 2008-01-03 Surmodics, Inc. Combination degradable and non-degradable matrices for active agent delivery
DE602007008125D1 (de) * 2006-10-31 2010-09-09 Surmodics Pharmaceuticals Inc Kugelförmige polymer-teilchen
SG187403A1 (en) 2007-09-28 2013-02-28 Engene Inc High concentration chitosan-nucleic acid polyplex compositions
US7988859B2 (en) * 2009-02-05 2011-08-02 Chromatan Inc. Countercurrent tangential chromatography methods, systems, and apparatus
WO2010102066A1 (en) 2009-03-05 2010-09-10 Bend Research, Inc. Dextran polymer powder for inhalation administration of pharmaceuticals
RU2554740C2 (ru) * 2009-05-01 2015-06-27 Апталис Фарматек, Инк. Композиции перорально распадающихся таблеток, содержащие комбинации высоко- и низкодозовых лекарственных средств
MA33466B1 (fr) 2009-07-31 2012-07-03 Sanofi Aventis Deutschland Composition d'insuline à longue duree d'action
NZ598021A (en) 2009-07-31 2014-05-30 Sanofi Aventis Deutschland Prodrugs comprising an insulin linker conjugate
CN102686245B (zh) 2009-10-29 2015-09-30 阿森迪斯药物股份有限公司 可生物降解水凝胶的消毒
EP2525899A1 (de) * 2010-01-22 2012-11-28 Lonza Walkersville, Inc. Verfahren und vorrichtung mit hohem ertrag für volumenreduzierung und waschung therapeutischer zellen durch tangentialflussfilterung
WO2011100458A2 (en) * 2010-02-10 2011-08-18 Bioo Scientific Corporation Methods for fractionating and processing microparticles from biological samples and using them for biomarker discovery
EP2555752B1 (de) 2010-04-09 2019-06-26 Pacira Pharmaceuticals, Inc. Verfahren zur formulierung von multivesikulären liposomen
US8815294B2 (en) 2010-09-03 2014-08-26 Bend Research, Inc. Pharmaceutical compositions of dextran polymer derivatives and a carrier material
EP2438930A1 (de) 2010-09-17 2012-04-11 Sanofi-Aventis Deutschland GmbH Prodrug mit einem exendinbindenden Konjugat
US9084727B2 (en) 2011-05-10 2015-07-21 Bend Research, Inc. Methods and compositions for maintaining active agents in intra-articular spaces
KR102046968B1 (ko) 2011-11-04 2019-12-02 닛토덴코 가부시키가이샤 지질-핵산입자를 멸균생성을 위한 단일 용도 시스템
EP2682168A1 (de) 2012-07-02 2014-01-08 Millipore Corporation Reinigung biologischer Moleküle
EP2730333A1 (de) 2012-11-08 2014-05-14 Sanofi-Aventis Deutschland GmbH Mischsystem zum Verarbeiten empfindlicher Substanzen
KR102274714B1 (ko) 2013-03-13 2021-07-09 씨젠 인크. 사이클로덱스트린 및 항체-약물 포합체 제형
EP3148713B1 (de) * 2014-05-27 2025-02-12 Artificial Cell Technologies, Inc. Automatischer schicht-für-schichtaufbau von mehrschichtigen überzogenen kernen durch tff
US9439864B2 (en) 2014-07-07 2016-09-13 Antriabio, Inc. Solvent extraction from biodegradable microparticles
PT108368B (pt) * 2015-03-31 2018-11-05 Hovione Farm S A Produção contínua de partículas
EP3589666B1 (de) * 2017-02-28 2021-01-13 Total Research & Technology Feluy Verfahren zur herstellung eines monovinylaromatischen polymers, das recyceltes post-verbraucher-polystyrol enthält und anlage zur herstellung eines monovinylaromatischen polymers, das recyceltes post-verbraucher-polystyrol enthält
WO2019173752A1 (en) 2018-03-08 2019-09-12 Repligen Corporation Tangential flow depth filtration systems and methods of filtration using same
JP7519912B2 (ja) * 2018-05-25 2024-07-22 レプリゲン・コーポレイション タンジェンシャルフローフィルトレーションのシステムおよび方法
CN110038350A (zh) * 2019-04-18 2019-07-23 苏州星烁纳米科技有限公司 纯化纳米晶溶液的装置及纯化方法
CN112870533B (zh) * 2020-12-21 2022-06-14 科塞尔医疗科技（苏州）有限公司 载药微球制备装置
CN112808188A (zh) * 2021-02-07 2021-05-18 浙江美华鼎昌医药科技有限公司 一种物料转移速度可控的相分离装置
WO2023099536A1 (en) * 2021-12-02 2023-06-08 Microcaps Ag Capsule gelation quenching unit

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Also Published As

Publication number Publication date
ATE381963T1 (de) 2008-01-15
EP1444033A1 (de) 2004-08-11
WO2003035244A1 (en) 2003-05-01
EP1306127A1 (de) 2003-05-02
CA2464668C (en) 2011-06-14
CA2464668A1 (en) 2003-05-01
EP1306127B2 (de) 2011-09-07
EP1306127B1 (de) 2007-12-26
DE60132094T2 (de) 2008-12-11
US7468151B2 (en) 2008-12-23
US20050084536A1 (en) 2005-04-21
DE60132094T3 (de) 2012-02-02

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: OCTOPLUS SCIENCES B.V., LEIDEN, NL

8363 Opposition against the patent
8327 Change in the person/name/address of the patent owner

Owner name: OCTOPLUS POLYACTIVE SCIENCES B.V., LEIDEN, NL

R102 Epo decision maintaining patent in amended form now final

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