[go: up one dir, main page]

DE60130394D1 - Gene, die im Zusammenhang mit der Biosynthese von ML-236B stehen - Google Patents

Gene, die im Zusammenhang mit der Biosynthese von ML-236B stehen

Info

Publication number
DE60130394D1
DE60130394D1 DE60130394T DE60130394T DE60130394D1 DE 60130394 D1 DE60130394 D1 DE 60130394D1 DE 60130394 T DE60130394 T DE 60130394T DE 60130394 T DE60130394 T DE 60130394T DE 60130394 D1 DE60130394 D1 DE 60130394D1
Authority
DE
Germany
Prior art keywords
biosynthesis
genes related
genes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60130394T
Other languages
English (en)
Other versions
DE60130394T2 (de
Inventor
Hiroji Yoshikawa
Yuki Abe
Chiho Ono
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Sankyo Co Ltd
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Application granted granted Critical
Publication of DE60130394D1 publication Critical patent/DE60130394D1/de
Publication of DE60130394T2 publication Critical patent/DE60130394T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/385—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from Penicillium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60130394T 2000-04-18 2001-04-18 Gene, die im Zusammenhang mit der Biosynthese von ML-236B stehen Expired - Lifetime DE60130394T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2000116591 2000-04-18
JP2000116591 2000-04-18
JP2000117458 2000-04-19
JP2000117458 2000-04-19

Publications (2)

Publication Number Publication Date
DE60130394D1 true DE60130394D1 (de) 2007-10-25
DE60130394T2 DE60130394T2 (de) 2008-06-19

Family

ID=26590305

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60130394T Expired - Lifetime DE60130394T2 (de) 2000-04-18 2001-04-18 Gene, die im Zusammenhang mit der Biosynthese von ML-236B stehen

Country Status (23)

Country Link
US (3) US7056710B2 (de)
EP (1) EP1149919B1 (de)
KR (1) KR100632174B1 (de)
CN (1) CN1325959B (de)
AR (1) AR034550A1 (de)
AT (1) ATE373101T1 (de)
AU (1) AU783319B2 (de)
BR (1) BR0101518A (de)
CA (1) CA2342397C (de)
CY (1) CY1106985T1 (de)
CZ (1) CZ20011367A3 (de)
DE (1) DE60130394T2 (de)
DK (1) DK1149919T3 (de)
ES (1) ES2293966T3 (de)
HU (1) HUP0101569A3 (de)
IL (1) IL142619A (de)
MX (1) MXPA01003913A (de)
NO (1) NO328653B1 (de)
NZ (1) NZ511166A (de)
PL (1) PL202457B1 (de)
PT (1) PT1149919E (de)
RU (1) RU2236463C2 (de)
TW (1) TWI312807B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007147827A2 (en) * 2006-06-22 2007-12-27 Dsm Ip Assets B.V. Production of pravastatin
CN102171328A (zh) * 2008-09-24 2011-08-31 帝斯曼知识产权资产管理有限公司 经改进的斯达汀生产
WO2010069914A1 (en) * 2008-12-19 2010-06-24 Dsm Ip Assets B.V. Statin transcription regulators
EP3134098A1 (de) * 2014-04-23 2017-03-01 Danmarks Tekniske Universitet Statinwiderstand und -export
CN115851654B (zh) * 2022-11-09 2025-02-07 江西省农业科学院植物保护研究所 一种芦笋茎枯病菌聚酮体合成酶及其编码基因和应用
CN119735638B (zh) * 2024-12-30 2025-08-15 广东海洋大学深圳研究院 咸鲜双功能呈味肽及其制备方法和应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS572240A (en) 1980-06-06 1982-01-07 Sankyo Co Ltd Ml-236b derivative
US5179013A (en) * 1987-02-02 1993-01-12 Sankyo Company, Limited Cytochrome P-450 enzymes
US5849541A (en) 1993-11-02 1998-12-15 Merck & Co., Inc. DNA encoding triol polyketide synthase
NZ299835A (en) * 1995-11-29 1997-08-22 Sankyo Co Actinomycete promoter for the expression of p-450 cytochromes
KR100186758B1 (ko) * 1996-08-09 1999-04-01 영진약품공업 주식회사 프라바스타틴(pravastatin)전구체의제조방법
US6391583B1 (en) 1998-12-18 2002-05-21 Wisconsin Alumni Research Foundation Method of producing antihypercholesterolemic agents
WO2001012814A1 (fr) 1999-08-11 2001-02-22 Sankyo Company, Limited Adn lie a la biosynthese ml-236b
FR2801648B1 (fr) * 1999-11-30 2002-06-21 Commissariat Energie Atomique Injecteur a vapeur haute pression comportant un drain axial

Also Published As

Publication number Publication date
PL202457B1 (pl) 2009-06-30
HUP0101569A2 (hu) 2002-05-29
RU2236463C2 (ru) 2004-09-20
EP1149919A2 (de) 2001-10-31
NO20011890L (no) 2001-10-19
NZ511166A (en) 2002-11-26
AU3709201A (en) 2001-10-25
MXPA01003913A (es) 2003-08-20
PT1149919E (pt) 2007-12-17
CY1106985T1 (el) 2012-09-26
CA2342397C (en) 2011-08-23
CZ20011367A3 (cs) 2001-12-12
NO20011890D0 (no) 2001-04-17
US20030078395A1 (en) 2003-04-24
IL142619A (en) 2008-03-20
HU0101569D0 (en) 2001-06-28
US20050214909A1 (en) 2005-09-29
US20070111293A1 (en) 2007-05-17
EP1149919B1 (de) 2007-09-12
ES2293966T3 (es) 2008-04-01
NO328653B1 (no) 2010-04-19
HUP0101569A3 (en) 2005-01-28
HK1037683A1 (en) 2002-02-15
DK1149919T3 (da) 2007-12-03
ATE373101T1 (de) 2007-09-15
TWI312807B (en) 2009-08-01
AR034550A1 (es) 2004-03-03
DE60130394T2 (de) 2008-06-19
EP1149919A3 (de) 2002-02-06
CN1325959A (zh) 2001-12-12
PL347118A1 (en) 2001-10-22
KR100632174B1 (ko) 2006-10-11
AU783319B2 (en) 2005-10-13
KR20010098713A (ko) 2001-11-08
CA2342397A1 (en) 2001-10-18
US7056710B2 (en) 2006-06-06
BR0101518A (pt) 2001-11-13
CN1325959B (zh) 2010-05-05

Similar Documents

Publication Publication Date Title
AU2002329667A1 (en) Specific inhibition of gene expression by small double stranded rnas
AU2002245184A1 (en) Nucleic acid amplification
EP1438392A4 (de) Zellpopulationen, die cd49c und cd90 exprimieren
MXPA02001741A (es) Procedimiento para generar informacion del hueco de ascensor que sirve a un mando de ascensor.
AU2002306374A1 (en) Genes with ES cell-specific expression
AU2003220249A1 (en) Improved nucleic acid amplification
DE60130394D1 (de) Gene, die im Zusammenhang mit der Biosynthese von ML-236B stehen
BR0214201B1 (pt) sabonete em barra.
MXPA03004166A (es) Nuevos usos de combinaciones de agonistas de 5-ht1a e inhibidores de la recaptacion de serotonina.
AU2002366435A1 (en) Nucleic acid amplification
GB0122232D0 (en) Gene expression
AU2001247444A1 (en) Erbeta-mediated gene expression
IT1319226B1 (it) Cerchione con rivestimento decorativo.
DK1325138T3 (da) Optimeret messenger rna
FR2883297B1 (fr) Genes de la biosynthese de la monacoline k
IT1317864B1 (it) Composizioni di polimeri acrilici.
AU2002211600A1 (en) Gene expression profiling of antidepressant action in the brain
ATE517988T1 (de) Neue gene, die neue proteolytische enzyme codieren
IT1314521B1 (it) Computer per immersioni.
AUPR232800A0 (en) Gene expression
IT251459Y1 (it) Cassetta per le lettere, atta a segnalare la presenza della postanella stessa.
ITBG20020013A1 (it) Carrello intelligente per supermercati.
IT1306686B1 (it) Aceto di birra.
BR8100632Y1 (pt) disposição construtiva aplicada em contentor.
ES1043227Y (es) Revestimiento acrilico mejorado.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition