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DE60126321D1 - Gelsystem zur ocularen verabreichung von arzneimitteln - Google Patents

Gelsystem zur ocularen verabreichung von arzneimitteln

Info

Publication number
DE60126321D1
DE60126321D1 DE60126321T DE60126321T DE60126321D1 DE 60126321 D1 DE60126321 D1 DE 60126321D1 DE 60126321 T DE60126321 T DE 60126321T DE 60126321 T DE60126321 T DE 60126321T DE 60126321 D1 DE60126321 D1 DE 60126321D1
Authority
DE
Germany
Prior art keywords
gelsystem
medicinal products
ocular administration
ocular
administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60126321T
Other languages
English (en)
Other versions
DE60126321T2 (de
Inventor
Erning Xia
V Smerbeck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bausch and Lomb Inc
Original Assignee
Bausch and Lomb Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bausch and Lomb Inc filed Critical Bausch and Lomb Inc
Publication of DE60126321D1 publication Critical patent/DE60126321D1/de
Application granted granted Critical
Publication of DE60126321T2 publication Critical patent/DE60126321T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
DE60126321T 2000-12-06 2001-12-03 Gelsystem zur ocularen verabreichung von arzneimitteln Expired - Lifetime DE60126321T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US731290 2000-12-06
US09/731,290 US6703039B2 (en) 2000-12-06 2000-12-06 Reversible gelling system for ocular drug delivery
PCT/US2001/046498 WO2002045683A2 (en) 2000-12-06 2001-12-03 Reversible gelling system for ocular drug delivery

Publications (2)

Publication Number Publication Date
DE60126321D1 true DE60126321D1 (de) 2007-03-15
DE60126321T2 DE60126321T2 (de) 2007-06-21

Family

ID=24938883

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60126321T Expired - Lifetime DE60126321T2 (de) 2000-12-06 2001-12-03 Gelsystem zur ocularen verabreichung von arzneimitteln

Country Status (12)

Country Link
US (1) US6703039B2 (de)
EP (1) EP1339386B1 (de)
JP (1) JP2004514731A (de)
KR (1) KR100840438B1 (de)
CN (1) CN100350976C (de)
AU (2) AU2002233978B2 (de)
BR (1) BR0116186A (de)
CA (1) CA2430995C (de)
DE (1) DE60126321T2 (de)
ES (1) ES2278799T3 (de)
MX (1) MXPA03005044A (de)
WO (1) WO2002045683A2 (de)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7935332B2 (en) * 2000-08-16 2011-05-03 Encore Health, Llc Presbyopia treatment by lens alteration
US8795706B2 (en) * 2000-08-16 2014-08-05 Encore Health, Llc Methods of treating ocular diseases using derivatives of lipoic acid
US8697109B2 (en) * 2000-08-16 2014-04-15 Encore Health, Llc Caged mercaptan and seleno-mercaptan compounds and methods of using them
US7914815B2 (en) * 2000-08-16 2011-03-29 Encore Health, Llc Method for delivery of pharmaceuticals for treating or preventing presbyopia
US8647612B2 (en) * 2008-03-05 2014-02-11 Encore Health, Llc Dithiol compounds, derivatives, and treatment of presbyopia
AU2005299748B2 (en) * 2004-10-21 2009-04-09 Tgel Bio Co., Ltd In situ controlled release drug delivery system
US8349352B2 (en) * 2005-02-04 2013-01-08 Auburn University Therapeutic contact lenses with anti-fungal delivery
US9238003B2 (en) 2005-02-04 2016-01-19 Auburn University Extended or continuous wear silicone hydrogel contact lenses for the extended release of comfort molecules
CA2597219C (en) * 2005-02-04 2014-04-15 Auburn University Contact drug delivery system
US8388995B1 (en) 2006-02-03 2013-03-05 Auburn University Controlled and extended delivery of hyaluronic acid and comfort molecules via a contact lens platform
US20080138408A1 (en) 2006-11-13 2008-06-12 Siddharth Venkatesh Drug delivery system and method
WO2008067403A2 (en) * 2006-11-28 2008-06-05 Encore Health Llc Presbyopia treatment by lens alteration
US9125807B2 (en) 2007-07-09 2015-09-08 Incept Llc Adhesive hydrogels for ophthalmic drug delivery
US20090142292A1 (en) * 2007-12-03 2009-06-04 Blackwell Richard I Method For The Mitigation of Symptoms of Dry Eye
US9044439B2 (en) * 2008-03-05 2015-06-02 Encore Health, Llc Low dose lipoic and pharmaceutical compositions and methods
WO2009111635A2 (en) 2008-03-05 2009-09-11 Encore Health, Llc Dithiol compounds, derivatives, and uses therefor
EP2396070B1 (de) 2009-02-12 2024-12-04 Incept Llc Wirkstofffreisetzung mit hydrogel-plugs
BRPI1008602A8 (pt) 2009-02-18 2018-01-02 Eyeon Particle Sciences Llc uso de co-polímero bi-funcional para as aplicações oftálmicas e outras aplicações tópicas e locais
PT2442645E (pt) * 2009-06-15 2014-11-05 Encore Health Llc Ésteres de colina
ES2634551T3 (es) 2010-04-03 2017-09-28 Praful Doshi Métodos para revestir una lente de contacto
US10413506B2 (en) 2010-04-03 2019-09-17 Praful Doshi Medical devices including medicaments and methods of making and using same including enhancing comfort, enhancing drug penetration, and treatment of myopia
US8961501B2 (en) 2010-09-17 2015-02-24 Incept, Llc Method for applying flowable hydrogels to a cornea
MX2013012308A (es) * 2011-04-22 2014-01-31 Alcon Res Ltd Composicion oftalmica con un sistema de mejoramiento de viscosidad de dos agentes mejoradores de viscosidad diferentes.
US10226417B2 (en) 2011-09-16 2019-03-12 Peter Jarrett Drug delivery systems and applications
US9827191B2 (en) 2012-05-03 2017-11-28 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
US11596599B2 (en) 2012-05-03 2023-03-07 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
EP3808339B1 (de) 2012-05-03 2025-11-12 Alcon Inc. Pharmazeutische nanopartikel mit verbessertem mukosalem transport
HK1208162A1 (en) 2012-05-03 2016-02-26 Kala Pharmaceuticals, Inc. Pharmaceutical nanoparticles showing improved mucosal transport
EP3021835B1 (de) * 2013-07-17 2017-05-10 Dow Global Technologies LLC Zusammensetzung zur anwendung auf einer schleimhaut mit hydroxyalkyl-methylcellulose
EP3113613A4 (de) 2014-03-03 2019-03-13 Encore Vision, Inc. Liponsäure-cholinester-zusammensetzungen und verfahren zur verwendung davon
EP3179988A4 (de) 2014-08-11 2018-11-14 Board of Supervisors of Lousiana State University Verabreichung von bioaktiven, nanoverkapselten antioxidantien
MX395496B (es) 2016-07-06 2025-03-25 Eyeon Particle Sciences Llc Uso de co-polímero bi-funcional para aplicaciones oftálmicas y otras aplicaciones tópicas y locales.
CN112203666A (zh) * 2018-05-29 2021-01-08 学校法人神野学园 外用组合物
CN115919754B (zh) * 2023-01-06 2023-09-12 广州家安化妆品有限公司 一种用于灭活病毒的粘膜消毒凝胶及其制备方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2703777A (en) 1950-05-02 1955-03-08 Iso Sol Company Inc Ophthalmological preparations and vehicles and method of making the same
US3549747A (en) 1968-02-20 1970-12-22 Flow Pharma Inc Contact lens wetting solution and method of using same
US3947573A (en) 1969-12-01 1976-03-30 Burton, Parsons And Company, Inc. Opthalmic solution
US3856919A (en) 1970-06-08 1974-12-24 Burton Parsons Chemicals Inc Ophthalmic solution
US3767788A (en) 1970-06-08 1973-10-23 Burton Parsons Chemicals Inc Ophthalmic solution
US3767789A (en) 1971-06-21 1973-10-23 Burton Parsons & Co Inc Method of providing a synthetic mucus in vivo
US3987163A (en) 1973-07-27 1976-10-19 Burton, Parsons And Company, Inc. Polystyrene sulfonate containing opthalmic solutions
US3907985A (en) 1973-07-27 1975-09-23 Burton Parsons And Company Inc Polystyrene sulfonate containing opthalmic solutions
US4029817A (en) 1973-09-24 1977-06-14 Allergan Pharmaceuticals Soft contact lens preserving solutions
US4120949A (en) 1977-10-05 1978-10-17 Cooper Laboratories, Inc. Ophthalmic solution
US4131651A (en) 1977-10-25 1978-12-26 Barnes-Hind Pharmaceuticals, Inc. Treatment of dry eye
US4409205A (en) 1979-03-05 1983-10-11 Cooper Laboratories, Inc. Ophthalmic solution
US4525346A (en) 1981-09-28 1985-06-25 Alcon Laboratories, Inc. Aqueous antimicrobial ophthalmic solutions
IL80298A (en) 1986-10-14 1993-01-31 Res & Dev Co Ltd Eye drops
GB2203039B (en) 1987-03-02 1990-10-24 American Cyanamid Co Stable ophthalmic preparations containing acetazolamide
US5141665A (en) 1987-03-31 1992-08-25 Sherman Laboratories, Inc. Cleaning, conditioning, storing and wetting system and method for rigid gas permeable contact lenses and other contact lenses
US5457093A (en) 1987-09-18 1995-10-10 Ethicon, Inc. Gel formulations containing growth factors
US5705485A (en) * 1987-09-18 1998-01-06 Ethicon, Inc. Gel formulations containing growth factors
US5405878A (en) * 1993-06-18 1995-04-11 Wilmington Partners L.P. Contact lens solution containing cationic glycoside
CA2125060C (en) 1993-07-02 1999-03-30 Henry P. Dabrowski Ophthalmic solution for artificial tears
US5585108A (en) 1994-12-30 1996-12-17 Nanosystems L.L.C. Formulations of oral gastrointestinal therapeutic agents in combination with pharmaceutically acceptable clays

Also Published As

Publication number Publication date
EP1339386A2 (de) 2003-09-03
ES2278799T3 (es) 2007-08-16
CA2430995C (en) 2008-10-14
CN1479631A (zh) 2004-03-03
WO2002045683A2 (en) 2002-06-13
AU3397802A (en) 2002-06-18
KR100840438B1 (ko) 2008-06-20
KR20030060977A (ko) 2003-07-16
CN100350976C (zh) 2007-11-28
US6703039B2 (en) 2004-03-09
EP1339386B1 (de) 2007-01-24
HK1059728A1 (en) 2004-07-16
MXPA03005044A (es) 2003-09-05
BR0116186A (pt) 2003-12-16
CA2430995A1 (en) 2002-06-13
US20020114778A1 (en) 2002-08-22
AU2002233978B2 (en) 2006-05-18
JP2004514731A (ja) 2004-05-20
DE60126321T2 (de) 2007-06-21
WO2002045683A3 (en) 2003-01-16

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Legal Events

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