DE60110087D1 - Verwendung von Carboanhydrase-Inhibitoren zur Prävention von diabetischer Retinopathie bei Diabetikern - Google Patents
Verwendung von Carboanhydrase-Inhibitoren zur Prävention von diabetischer Retinopathie bei DiabetikernInfo
- Publication number
- DE60110087D1 DE60110087D1 DE60110087T DE60110087T DE60110087D1 DE 60110087 D1 DE60110087 D1 DE 60110087D1 DE 60110087 T DE60110087 T DE 60110087T DE 60110087 T DE60110087 T DE 60110087T DE 60110087 D1 DE60110087 D1 DE 60110087D1
- Authority
- DE
- Germany
- Prior art keywords
- prevention
- diabetic retinopathy
- diabetics
- carbonic anhydrase
- anhydrase inhibitors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 206010012689 Diabetic retinopathy Diseases 0.000 title abstract 2
- 229940006133 antiglaucoma drug and miotics carbonic anhydrase inhibitors Drugs 0.000 title abstract 2
- 239000003489 carbonate dehydratase inhibitor Substances 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title abstract 2
- 206010038923 Retinopathy Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/382—Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/433—Thidiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Ophthalmology & Optometry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22435800P | 2000-08-11 | 2000-08-11 | |
| US224358P | 2000-08-11 | ||
| PCT/IS2001/000015 WO2002013800A2 (en) | 2000-08-11 | 2001-08-10 | Method for the prevention and treatment of retinopathy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60110087D1 true DE60110087D1 (de) | 2005-05-19 |
| DE60110087T2 DE60110087T2 (de) | 2005-09-29 |
Family
ID=22840318
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60110087T Expired - Fee Related DE60110087T2 (de) | 2000-08-11 | 2001-08-10 | Verwendung von Carboanhydrase-Inhibitoren zur Prävention von diabetischer Retinopathie bei Diabetikern |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20020055458A1 (de) |
| EP (1) | EP1307185B1 (de) |
| AT (1) | ATE292964T1 (de) |
| AU (1) | AU2001280093A1 (de) |
| CA (1) | CA2419158A1 (de) |
| DE (1) | DE60110087T2 (de) |
| WO (1) | WO2002013800A2 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030100594A1 (en) * | 2001-08-10 | 2003-05-29 | Pharmacia Corporation | Carbonic anhydrase inhibitor |
| WO2004108135A1 (en) * | 2003-05-30 | 2004-12-16 | Merck & Co., Inc. | Composition and method for treating macular disorders |
| WO2006091459A2 (en) * | 2005-02-24 | 2006-08-31 | Joslin Diabetes Center, Inc. | Compositions and methods for treating vascular permeability |
| US7670794B2 (en) * | 2005-11-04 | 2010-03-02 | Washington University | Managing glycemia status in diabetic patients |
| US20070110707A1 (en) * | 2005-11-04 | 2007-05-17 | Washington University | Method of treating diseases involving non-enzymatic glycation |
| PL2106260T3 (pl) * | 2007-01-25 | 2018-06-29 | NAIA Metabolic, Inc. | Środki uwrażliwiające na insulinę i sposoby leczenia |
| WO2008091692A2 (en) * | 2007-01-25 | 2008-07-31 | Joslin Diabetes Center, Inc. | Methods of diagnosing, treating, and preventing increased vascular permeability |
| HK1209041A1 (en) * | 2012-05-24 | 2016-03-24 | Verva Pharmaceuticals Ltd | A method of weight reduction |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4386098A (en) * | 1981-11-03 | 1983-05-31 | Merck & Co., Inc. | 6-Hydroxy-2-benzothiazolesulfonamide for the topical treatment of elevated intraocular pressure |
| US4797413A (en) * | 1986-05-14 | 1989-01-10 | Merck & Co., Inc. | Thieno thiopyran sulfonamide derivatives, pharmaceutical compositions and use |
| US4677115A (en) * | 1984-12-12 | 1987-06-30 | Merck & Co., Inc. | Antiglaucoma thieno-thiopyran and thieno-thiepin sulfonamide derivatives, compositions, and method of use thereof |
| US6156785A (en) * | 1998-01-23 | 2000-12-05 | Merck Sharp & Dohme B.V. | Method for increasing oxygen tension in the optic nerve and retina |
| WO1999044603A1 (en) * | 1998-03-06 | 1999-09-10 | Sponsel William E | Composition and method for treating macular disorders |
| US5948801A (en) * | 1998-03-09 | 1999-09-07 | Alcon Laboratories, Inc. | Treatment of retinal edema with brinzolamide |
| US6242442B1 (en) * | 1998-12-17 | 2001-06-05 | Alcon Laboratories, Inc. | Brinzolamide and brimonidine for treating ocular conditions |
-
2001
- 2001-08-10 US US09/925,659 patent/US20020055458A1/en not_active Abandoned
- 2001-08-10 AU AU2001280093A patent/AU2001280093A1/en not_active Abandoned
- 2001-08-10 WO PCT/IS2001/000015 patent/WO2002013800A2/en not_active Ceased
- 2001-08-10 AT AT01958375T patent/ATE292964T1/de not_active IP Right Cessation
- 2001-08-10 CA CA002419158A patent/CA2419158A1/en not_active Abandoned
- 2001-08-10 EP EP01958375A patent/EP1307185B1/de not_active Expired - Lifetime
- 2001-08-10 DE DE60110087T patent/DE60110087T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1307185A2 (de) | 2003-05-07 |
| CA2419158A1 (en) | 2002-02-21 |
| AU2001280093A1 (en) | 2002-02-25 |
| WO2002013800A3 (en) | 2002-05-02 |
| ATE292964T1 (de) | 2005-04-15 |
| WO2002013800A2 (en) | 2002-02-21 |
| EP1307185B1 (de) | 2005-04-13 |
| DE60110087T2 (de) | 2005-09-29 |
| US20020055458A1 (en) | 2002-05-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |