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DE60109938D1 - Zusammenstellungen die aktive stilbenoidverbindungen enthalten zur senkung des triglyceridspiegels - Google Patents

Zusammenstellungen die aktive stilbenoidverbindungen enthalten zur senkung des triglyceridspiegels

Info

Publication number
DE60109938D1
DE60109938D1 DE60109938T DE60109938T DE60109938D1 DE 60109938 D1 DE60109938 D1 DE 60109938D1 DE 60109938 T DE60109938 T DE 60109938T DE 60109938 T DE60109938 T DE 60109938T DE 60109938 D1 DE60109938 D1 DE 60109938D1
Authority
DE
Germany
Prior art keywords
styleneoid
triglycerid
mirror
compositions
active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60109938T
Other languages
English (en)
Other versions
DE60109938T2 (de
Inventor
D Inman
Craig Hoppe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Insmed Inc
Original Assignee
Insmed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Insmed Inc filed Critical Insmed Inc
Application granted granted Critical
Publication of DE60109938D1 publication Critical patent/DE60109938D1/de
Publication of DE60109938T2 publication Critical patent/DE60109938T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Seasonings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Optical Head (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60109938T 2000-08-16 2001-08-15 Zusammenstellungen die aktive stilbenoidverbindungen enthalten zur senkung des triglyceridspiegels Expired - Lifetime DE60109938T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US22570400P 2000-08-16 2000-08-16
US225704P 2000-08-16
US09/920,304 US6541522B2 (en) 2000-08-16 2001-08-02 Methods of using compositions containing hypotriglyceridemically active stilbenoids
US920304 2001-08-02
PCT/US2001/025383 WO2002013806A2 (en) 2000-08-16 2001-08-15 Compositions containing hypotriglyceridemically active stilbenoids

Publications (2)

Publication Number Publication Date
DE60109938D1 true DE60109938D1 (de) 2005-05-12
DE60109938T2 DE60109938T2 (de) 2005-09-08

Family

ID=26919840

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60109938T Expired - Lifetime DE60109938T2 (de) 2000-08-16 2001-08-15 Zusammenstellungen die aktive stilbenoidverbindungen enthalten zur senkung des triglyceridspiegels

Country Status (6)

Country Link
US (1) US6541522B2 (de)
EP (1) EP1311258B1 (de)
AT (1) ATE292460T1 (de)
AU (1) AU2001283355A1 (de)
DE (1) DE60109938T2 (de)
WO (1) WO2002013806A2 (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020058708A1 (en) * 2000-08-16 2002-05-16 Inman Wayne D. Compositions containing hypotriglyceridemically active stilbenoids
US6552085B2 (en) * 2000-08-16 2003-04-22 Insmed Incorporated Compositions containing hypoglycemically active stilbenoids
US6410596B1 (en) * 2000-08-16 2002-06-25 Insmed Incorporated Compositions containing hypoglycemically active stillbenoids
US7977049B2 (en) * 2002-08-09 2011-07-12 President And Fellows Of Harvard College Methods and compositions for extending the life span and increasing the stress resistance of cells and organisms
US20050080021A1 (en) * 2002-08-15 2005-04-14 Joseph Tucker Nitric oxide donating derivatives of stilbenes, polyphenols and flavonoids for the treatment of cardiovascular disorders
US20050080024A1 (en) * 2002-08-15 2005-04-14 Joseph Tucker Nitric oxide donating derivatives for the treatment of cardiovascular disorders
US20060025337A1 (en) * 2003-07-01 2006-02-02 President And Fellows Of Harvard College Sirtuin related therapeutics and diagnostics for neurodegenerative diseases
JP2007530417A (ja) * 2003-07-01 2007-11-01 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 細胞及び生物の寿命及びストレス応答を操作するための組成物
CN101247793B (zh) 2003-12-29 2013-04-10 哈佛大学校长及研究员协会 治疗或预防肥胖和胰岛素抗性病症的组合物
US8017634B2 (en) * 2003-12-29 2011-09-13 President And Fellows Of Harvard College Compositions for treating obesity and insulin resistance disorders
AR047658A1 (es) 2004-02-03 2006-02-01 Cargill Inc Concentrado de proteinas y corriente acuosa con carbohidratos hidrosolubles
JP2008503479A (ja) * 2004-06-16 2008-02-07 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ Ｂａｘ媒介性アポトーシスを調節する方法及び組成物
WO2006004722A2 (en) * 2004-06-30 2006-01-12 Biomol Research Laboratories, Inc. Compositions and methods for selectively activating human sirtuins
CA2584485C (en) * 2004-10-20 2013-12-31 Resverlogix Corp. Stilbenes and chalcones for the prevention and treatment of cardiovascular diseases
WO2006138418A2 (en) * 2005-06-14 2006-12-28 President And Fellows Of Harvard College Improvement of cognitive performance with sirtuin activators
US20070149466A1 (en) * 2005-07-07 2007-06-28 Michael Milburn Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders
EP1909788A2 (de) * 2005-07-29 2008-04-16 Resverlogix Corp. Pharmazeutische zusammensetzungen zur prävention und behandlung komplexer erkrankungen und deren freisetzung mittels einsetzbarer medizinprodukte
US20070029101A1 (en) * 2005-08-05 2007-02-08 Paul Croas Hammerhead forcible entry tool used to defeat burglar bars
WO2008075528A1 (ja) * 2006-12-20 2008-06-26 Kurohime Medical Co., Ltd. 甘茶の用途
SI2118074T1 (sl) 2007-02-01 2014-05-30 Resverlogix Corp. Spojine za preprečevanje in zdravljenje kardiovaskularnih bolezni
US7824714B2 (en) * 2008-06-13 2010-11-02 Development Center For Biotechnology Chinese herb extract for treating dementia and preparation method thereof
AU2009262252B2 (en) 2008-06-26 2013-05-02 Resverlogix Corp. Methods of preparing quinazolinone derivatives
NZ594332A (en) 2009-01-08 2013-09-27 Resverlogix Corp Compounds for the prevention and treatment of cardiovascular disease
CN105859639A (zh) 2009-03-18 2016-08-17 雷斯韦洛吉克斯公司 新的抗炎剂
BRPI1014956B8 (pt) 2009-04-22 2021-05-25 Resverlogix Corp agentes anti-inflamatórios
US8815310B2 (en) * 2011-01-10 2014-08-26 Morteza Naghavi Compositions for boosting metabolism, assisting weight loss, and promoting cardiovascular health
AU2012330885B2 (en) 2011-11-01 2016-10-06 Resverlogix Corp. Oral immediate release formulations for substituted quinazolinones
CN105030750B (zh) * 2011-12-23 2018-08-28 中国医学科学院医药生物技术研究所 一组木豆素结构类似化合物在抗丙肝病毒和抗艾滋病毒的应用
US9765039B2 (en) 2012-11-21 2017-09-19 Zenith Epigenetics Ltd. Biaryl derivatives as bromodomain inhibitors
US9073878B2 (en) 2012-11-21 2015-07-07 Zenith Epigenetics Corp. Cyclic amines as bromodomain inhibitors
CA2895905A1 (en) 2012-12-21 2014-06-26 Zenith Epigenetics Corp. Novel heterocyclic compounds as bromodomain inhibitors
EP2801357A1 (de) * 2013-05-10 2014-11-12 IMD Natural Solutions GmbH Carboxylierte Stilbene zur Aktivierung von AMPK und Sirtuinen
CN103992290B (zh) * 2013-05-14 2016-07-06 中国医学科学院医药生物技术研究所 二芳基乙烯结构类似化合物及其制备方法和应用
CN104547001A (zh) * 2015-01-09 2015-04-29 刘长河 一种从木豆叶中提取抗骨质疏松和降脂物的工艺
JO3789B1 (ar) 2015-03-13 2021-01-31 Resverlogix Corp التراكيب والوسائل العلاجية المعتمدة لمعالجة الامراض المتعلقة بالمتممة
EP3641564B1 (de) * 2017-06-22 2024-05-22 Symrise AG Geschmacksmodulierende aromastoffe
CN112175856B (zh) * 2019-07-05 2022-10-21 中粮生物科技股份有限公司 用于枯草芽孢杆菌发酵的固体培养基以及枯草芽孢杆菌固体菌剂及其制备方法和应用
CN116761791A (zh) * 2020-11-05 2023-09-15 雀巢产品有限公司 作为ampk活化剂的取代的雷琐酸化合物及其用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62270529A (ja) * 1986-05-19 1987-11-24 Nippon Haipotsukusu:Kk 抗アレルギ−剤
US5827898A (en) 1996-10-07 1998-10-27 Shaman Pharmaceuticals, Inc. Use of bisphenolic compounds to treat type II diabetes
FR2778337B1 (fr) 1998-05-05 2001-08-31 Inst Nat Sante Rech Med Antagonistes des ligands du recepteur des arylhydrocarbures
BR9915687A (pt) 1998-11-25 2001-12-04 Nutri Pharma As Composição compreendendo proteìna de soja,fibras de dieta e um composto fitoestrogênio eseu uso na prevenção e/ou tratamento de doençascardiovasculares
DE10015525A1 (de) 2000-03-30 2001-10-11 Deutsches Krebsforsch Synthetische Derivate von Lunularsäure, Arzneimittel enthaltend diese Verbindung, Verfahren zur Herstellung der Lunularsäurederivate sowie deren Verwendung
US20020058708A1 (en) 2000-08-16 2002-05-16 Inman Wayne D. Compositions containing hypotriglyceridemically active stilbenoids
US6410596B1 (en) 2000-08-16 2002-06-25 Insmed Incorporated Compositions containing hypoglycemically active stillbenoids
US6552085B2 (en) 2000-08-16 2003-04-22 Insmed Incorporated Compositions containing hypoglycemically active stilbenoids

Also Published As

Publication number Publication date
ATE292460T1 (de) 2005-04-15
WO2002013806A3 (en) 2002-10-31
EP1311258A2 (de) 2003-05-21
DE60109938T2 (de) 2005-09-08
US20020055541A1 (en) 2002-05-09
US6541522B2 (en) 2003-04-01
AU2001283355A1 (en) 2002-02-25
WO2002013806A2 (en) 2002-02-21
EP1311258B1 (de) 2005-04-06

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Legal Events

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