[go: up one dir, main page]

DE60107234D1 - Antitubulinanordnung und zellenwachstumshemmstoff "dioxostatin" - Google Patents

Antitubulinanordnung und zellenwachstumshemmstoff "dioxostatin"

Info

Publication number
DE60107234D1
DE60107234D1 DE60107234T DE60107234T DE60107234D1 DE 60107234 D1 DE60107234 D1 DE 60107234D1 DE 60107234 T DE60107234 T DE 60107234T DE 60107234 T DE60107234 T DE 60107234T DE 60107234 D1 DE60107234 D1 DE 60107234D1
Authority
DE
Germany
Prior art keywords
dioxostatin
inhibitant
antitubulin
arrangement
cell growth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60107234T
Other languages
English (en)
Other versions
DE60107234T2 (de
Inventor
R Pettit
W Lippert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arizona State University ASU
Original Assignee
Arizona State University ASU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arizona State University ASU filed Critical Arizona State University ASU
Application granted granted Critical
Publication of DE60107234D1 publication Critical patent/DE60107234D1/de
Publication of DE60107234T2 publication Critical patent/DE60107234T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/22—Radicals substituted by singly bound oxygen or sulfur atoms etherified
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60107234T 2000-05-09 2001-05-08 Antitubulinanordnung und zellenwachstumshemmstoff "dioxostatin" Expired - Fee Related DE60107234T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20277000P 2000-05-09 2000-05-09
US202770P 2000-05-09
PCT/US2001/014790 WO2001084929A1 (en) 2000-05-09 2001-05-08 Antitubulin assembly and cell growth inhibitor denominated 'dioxostatin'

Publications (2)

Publication Number Publication Date
DE60107234D1 true DE60107234D1 (de) 2004-12-23
DE60107234T2 DE60107234T2 (de) 2005-10-27

Family

ID=22751187

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60107234T Expired - Fee Related DE60107234T2 (de) 2000-05-09 2001-05-08 Antitubulinanordnung und zellenwachstumshemmstoff "dioxostatin"

Country Status (7)

Country Link
US (1) US20040122083A1 (de)
EP (1) EP1283672B1 (de)
JP (1) JP2004515452A (de)
AT (1) ATE282313T1 (de)
CA (1) CA2408220A1 (de)
DE (1) DE60107234T2 (de)
WO (1) WO2001084929A1 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7244230B2 (en) * 2002-11-08 2007-07-17 Siemens Medical Solutions Usa, Inc. Computer aided diagnostic assistance for medical imaging
US20050131837A1 (en) 2003-12-15 2005-06-16 Sanctis Jeanne D. Method, system and program product for communicating e-commerce content over-the-air to mobile devices
US8370269B2 (en) 2004-06-02 2013-02-05 Overstock.Com, Inc. System and methods for electronic commerce using personal and business networks
US7879369B2 (en) 2007-09-18 2011-02-01 Selvamedica, Llc Combretum laurifolium Mart. extract and methods of extracting and using such extract
WO2009067706A1 (en) 2007-11-21 2009-05-28 Oxigene, Inc. Method for treating hematopoietic neoplasms
US8583480B2 (en) 2007-12-21 2013-11-12 Overstock.Com, Inc. System, program product, and methods for social network advertising and incentives for same
US9747622B1 (en) 2009-03-24 2017-08-29 Overstock.Com, Inc. Point-and-shoot product lister
US9047642B2 (en) 2011-03-24 2015-06-02 Overstock.Com, Inc. Social choice engine
US10546262B2 (en) 2012-10-19 2020-01-28 Overstock.Com, Inc. Supply chain management system
US10949876B2 (en) 2012-10-29 2021-03-16 Overstock.Com, Inc. System and method for management of email marketing campaigns
WO2014089177A2 (en) 2012-12-04 2014-06-12 Massachusetts Institute Of Technology Compounds, conjugates and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines
US11676192B1 (en) 2013-03-15 2023-06-13 Overstock.Com, Inc. Localized sort of ranked product recommendations based on predicted user intent
CA2905509A1 (en) 2013-03-15 2014-09-18 Memorial Sloan-Kettering Cancer Center Hsp90-targeted cardiac imaging and therapy
US11023947B1 (en) 2013-03-15 2021-06-01 Overstock.Com, Inc. Generating product recommendations using a blend of collaborative and content-based data
US10810654B1 (en) 2013-05-06 2020-10-20 Overstock.Com, Inc. System and method of mapping product attributes between different schemas
US9483788B2 (en) 2013-06-25 2016-11-01 Overstock.Com, Inc. System and method for graphically building weighted search queries
US10929890B2 (en) 2013-08-15 2021-02-23 Overstock.Com, Inc. System and method of personalizing online marketing campaigns
US10872350B1 (en) 2013-12-06 2020-12-22 Overstock.Com, Inc. System and method for optimizing online marketing based upon relative advertisement placement
FR3029911B1 (fr) * 2014-12-12 2018-03-09 L'oreal Nouveaux composes 1,2-diphenylethylene glycol pour lutter contre le vieillissement cutane et utilisation en cosmetique
WO2016130969A1 (en) 2015-02-13 2016-08-18 George Robert Pettit Silstatin compounds
JP2018523712A (ja) 2015-08-18 2018-08-23 マテオン セラピューティクス, インク.Mateon Therapeutics, Inc. 腫瘍に対する免疫調節療法を向上させる為のｖｄａｓの使用
WO2017197045A1 (en) 2016-05-11 2017-11-16 Movassaghi Mohammad Convergent and enantioselective total synthesis of communesin analogs
US10534845B2 (en) 2016-05-11 2020-01-14 Overstock.Com, Inc. System and method for optimizing electronic document layouts
US10970769B2 (en) 2017-03-02 2021-04-06 Overstock.Com, Inc. Method and system for optimizing website searching with user pathing
WO2018209239A1 (en) 2017-05-11 2018-11-15 Massachusetts Institute Of Technology Potent agelastatin derivatives as modulators for cancer invasion and metastasis
US10640508B2 (en) 2017-10-13 2020-05-05 Massachusetts Institute Of Technology Diazene directed modular synthesis of compounds with quaternary carbon centers
WO2019094709A1 (en) 2017-11-09 2019-05-16 Pettit George R Betulastatin compounds
US11514493B1 (en) 2019-03-25 2022-11-29 Overstock.Com, Inc. System and method for conversational commerce online
US11205179B1 (en) 2019-04-26 2021-12-21 Overstock.Com, Inc. System, method, and program product for recognizing and rejecting fraudulent purchase attempts in e-commerce
US11535634B2 (en) 2019-06-05 2022-12-27 Massachusetts Institute Of Technology Compounds, conjugates, and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines and uses thereof
US11734368B1 (en) 2019-09-26 2023-08-22 Overstock.Com, Inc. System and method for creating a consistent personalized web experience across multiple platforms and channels
US12030888B2 (en) 2021-02-24 2024-07-09 Massachusetts Institute Of Technology Himastatin derivatives, and processes of preparation thereof, and uses thereof
CN113511962A (zh) * 2021-06-30 2021-10-19 上海应用技术大学 一种氟代乙氧基毛兰素及其制备方法与应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW325458B (en) * 1993-09-08 1998-01-21 Ajinomoto Kk Stilbene derivatives and pharmaceutical compositions comprising the same for anti-cancer
JP4187441B2 (ja) * 1999-09-17 2008-11-26 ベイラー・ユニバーシテイ インドール含有およびコンブレタスタチン関連の抗有糸分裂および抗チューブリン重合薬剤

Also Published As

Publication number Publication date
CA2408220A1 (en) 2001-11-15
EP1283672B1 (de) 2004-11-17
US20040122083A1 (en) 2004-06-24
DE60107234T2 (de) 2005-10-27
JP2004515452A (ja) 2004-05-27
EP1283672A1 (de) 2003-02-19
ATE282313T1 (de) 2004-12-15
EP1283672A4 (de) 2003-06-04
WO2001084929A1 (en) 2001-11-15

Similar Documents

Publication Publication Date Title
ATE282313T1 (de) ANTITUBULINANORDNUNG UND ZELLENWACHSTUMSHEMMSTOFF ßDIOXOSTATINß
DE60012188D1 (de) Fungizide
PT1413582E (pt) Pirrolobenzodiazepinas dimericas
BG105967A (en) C(7) ester substituted taxanes and their use as antitumor agents
GB0128996D0 (en) Organic compounds
NO20034660D0 (no) Spiropyrazolforbindelser
ID29076A (id) Kombinasi senyawa aktif fungisida
IL145639A0 (en) C10 heterosubstituted acetate taxanes as antitumor agents
SE0004245D0 (sv) Novel compounds and their use
BRPI0112375B8 (pt) aplidinas como derivados antitumorais
EP1180024A4 (de) Z-styryl sulfonen als anti-krebsmittel
TR200201128T2 (tr) PDE4 inhibitörleri olarak tetrahidrotiyopiranfitalazinon türevleri.
EP1667976A4 (de) Isochinolinon-kaliumkanalinhibitoren
DK1204659T3 (da) Serotonerge benzofuraner
BG105964A (en) C(10) carbonate substituted taxanes and their use as antitumor agents
NO20014758L (no) C(7)-heterosubstituerte acetattaxaner som antitumormidler
BG105966A (en) C7 carbonate substituted taxanes and their application as antitumor agents
BG105965A (en) C10 ester substituted taxanes and their application as antitumor agents
NO20014757D0 (no) C(7)-karbamoyloksysubstituerte taksaner som antitumormidler
NO20014760L (no) C(10)-karbamoyloksysubstituerte taksaner som antitumormidler
ES2166710A1 (es) Nuevos compuestos heterociclicos con actividad antiinflamatoria.
GB0011927D0 (en) New use of citreamicins
WO2003033523A3 (en) Cytotoxic compounds
WO2003095459A3 (fr) Composes derives d'alcaloides et leur utilisation dans le traitement de malaria et cancer
ECSP982682A (es) Nueva 3, 4 diariltiazolina 2- uno o 2- tiono derivados, sus metodos de preparacion y su uso terapeutico

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee