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DE60103697D1 - Langwelligabsorbierende Bacteriochlorin-Alkyl-Aether- Analoge - Google Patents

Langwelligabsorbierende Bacteriochlorin-Alkyl-Aether- Analoge

Info

Publication number
DE60103697D1
DE60103697D1 DE60103697T DE60103697T DE60103697D1 DE 60103697 D1 DE60103697 D1 DE 60103697D1 DE 60103697 T DE60103697 T DE 60103697T DE 60103697 T DE60103697 T DE 60103697T DE 60103697 D1 DE60103697 D1 DE 60103697D1
Authority
DE
Germany
Prior art keywords
carbon atoms
alkyl
bacteriochlorin
long
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60103697T
Other languages
English (en)
Other versions
DE60103697T2 (de
Inventor
Ravindra K Pandey
Thomas J Dougherty
William R Potter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Health Research Inc
Original Assignee
Health Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Health Research Inc filed Critical Health Research Inc
Application granted granted Critical
Publication of DE60103697D1 publication Critical patent/DE60103697D1/de
Publication of DE60103697T2 publication Critical patent/DE60103697T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/22Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Shielding Devices Or Components To Electric Or Magnetic Fields (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Optical Modulation, Optical Deflection, Nonlinear Optics, Optical Demodulation, Optical Logic Elements (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DE60103697T 2000-06-12 2001-04-11 Langwelligabsorbierende Bacteriochlorin-Alkyl-Aether- Analoge Expired - Lifetime DE60103697T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US592150 1996-01-26
US09/592,150 US6624187B1 (en) 2000-06-12 2000-06-12 Long wave length absorbing bacteriochlorin alkyl ether analogs

Publications (2)

Publication Number Publication Date
DE60103697D1 true DE60103697D1 (de) 2004-07-15
DE60103697T2 DE60103697T2 (de) 2005-06-09

Family

ID=24369506

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60103697T Expired - Lifetime DE60103697T2 (de) 2000-06-12 2001-04-11 Langwelligabsorbierende Bacteriochlorin-Alkyl-Aether- Analoge

Country Status (7)

Country Link
US (1) US6624187B1 (de)
EP (1) EP1164136B1 (de)
JP (1) JP4976618B2 (de)
AT (1) ATE268777T1 (de)
AU (1) AU2984401A (de)
CA (1) CA2342064C (de)
DE (1) DE60103697T2 (de)

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US6127356A (en) 1993-10-15 2000-10-03 Duke University Oxidant scavengers
CA2309154C (en) * 1997-11-03 2010-02-16 Duke University Substituted porphyrins
AU2412800A (en) 1999-01-15 2000-08-01 Light Sciences Corporation Noninvasive vascular therapy
US6602274B1 (en) 1999-01-15 2003-08-05 Light Sciences Corporation Targeted transcutaneous cancer therapy
WO2000041725A2 (en) * 1999-01-15 2000-07-20 Light Sciences Corporation Therapeutic compositions for metabolic bone disorders or bone metastases
CA2359116C (en) * 1999-01-25 2009-03-17 National Jewish Medical And Research Center Substituted porphyrins
US7897140B2 (en) * 1999-12-23 2011-03-01 Health Research, Inc. Multi DTPA conjugated tetrapyrollic compounds for phototherapeutic contrast agents
EP1267935A2 (de) * 2000-01-12 2003-01-02 Light Sciences Corporation Behandlung von augenerkrankungen
US6624187B1 (en) 2000-06-12 2003-09-23 Health Research, Inc. Long wave length absorbing bacteriochlorin alkyl ether analogs
US20030069281A1 (en) * 2000-06-14 2003-04-10 Irwin Fridovich Tetrapyrroles
US20030050297A1 (en) 2001-01-19 2003-03-13 Crapo James D. Cancer therapy
AU2002312194B8 (en) * 2001-06-01 2008-05-15 Aeolus Sciences, Inc. Oxidant scavengers for treatment of diabetes or use in transplantation or induction of immune tolerance
US7041121B1 (en) * 2002-01-31 2006-05-09 Medtronicvidamed, Inc. Apparatus for treating prostate cancer and method for same
CA2488500A1 (en) * 2002-06-07 2003-12-18 Duke University Substituted porphyrins
EP1517684B1 (de) 2002-06-27 2009-07-22 Health Research, Inc. Fluorinierte chlorin und bacteriochlorin photosensitizer für fotodynamische therapie
EP1606291A2 (de) 2002-07-02 2005-12-21 Health Research, Inc. Effiziente synthese von pyropheophorbid-a und seiner derivate
IL152900A0 (en) * 2002-11-17 2003-06-24 Yeda Res & Dev Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses
JP5283172B2 (ja) 2005-03-28 2013-09-04 ザ ルブリゾル コーポレイション 潤滑剤中の添加剤としてのチタン化合物およびチタン錯体
KR20090108068A (ko) * 2007-01-09 2009-10-14 헬스 리서치 인코포레이티드 Pdt를 위한 치료적 hpph 투여량
CN102105146A (zh) 2008-05-23 2011-06-22 国立犹太保健医院 用于治疗与暴露于烷化物质有关的损伤的方法
GB0819594D0 (en) 2008-10-24 2008-12-03 Univ Coimbrra Process
BR112012022581A2 (pt) 2010-03-10 2016-08-30 Lubrizol Corp compostos e complexos de titânio e molibdênio como aditivos em lubrificantes
CN111171030B (zh) * 2018-11-12 2022-11-22 浙江海正药业股份有限公司 细菌叶绿素衍生物及其制备方法
CN110904016A (zh) * 2019-12-31 2020-03-24 内蒙古工业大学 一株重离子诱变类球红细菌高产辅酶q10的菌株及其应用

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US4753958A (en) 1985-02-07 1988-06-28 University Of Cal Photochemotherapy of epithelial diseases with derivatives of hematoporphyrins
US4883790A (en) 1987-01-20 1989-11-28 University Of British Columbia Wavelength-specific cytotoxic agents
US4968715A (en) 1988-07-06 1990-11-06 Health Research, Inc. Use of purified hematoporphyrin trimers in photodynamic therapy
US5190966A (en) 1988-07-06 1993-03-02 Health Research, Inc. Purified hematoporphyrin dimers and trimers useful in photodynamic therapy
US5093349A (en) 1988-07-20 1992-03-03 Health Research Inc. Photosensitizing agents
US5198460A (en) 1988-07-20 1993-03-30 Health Research Inc. Pyropheophorbides and their use in photodynamic therapy
US5002962A (en) 1988-07-20 1991-03-26 Health Research, Inc. Photosensitizing agents
US5111821A (en) 1988-11-08 1992-05-12 Health Research, Inc. Fluorometric method for detecting abnormal tissue using dual long-wavelength excitation
US5173504A (en) 1989-04-21 1992-12-22 Health Research, Inc. Bacteriochlorophyll-a derivatives useful in photodynamic therapy
US5171741A (en) 1989-04-21 1992-12-15 Health Research, Inc. Bacteriochlorophyll-a derivatives useful in photodynamic therapy
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US5074632A (en) 1990-03-07 1991-12-24 Health Research, Inc. Fiber optic diffusers and methods for manufacture of the same
US5330741A (en) 1992-02-24 1994-07-19 The Regents Of The University Of California Long-wavelength water soluble chlorin photosensitizers useful for photodynamic therapy and diagnosis of tumors
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US5817830A (en) 1992-08-14 1998-10-06 Trustees Of The University Of Pennsylvania Pyrrolic compounds
US5286474A (en) 1992-10-22 1994-02-15 Arizona Board Of Regents, A Body Corporate, Acting For And On Behalf The Arizona State University Use of carotenoporphyrins as tumor localizing agents for diagnosis
DE4310643A1 (de) * 1993-04-01 1994-10-06 Merck Patent Gmbh Cyclische Adhäsionsinhibitoren
DE4427979A1 (de) * 1993-11-15 1996-02-15 Cassella Ag Substituierte 5-Ring-Heterocyclen, ihre Herstellung und ihre Verwendung
US5498710A (en) 1994-04-22 1996-03-12 Health Research, Inc. Alkyl ether analogues of benzoporphyrin derivatives
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US6071944A (en) 1997-11-12 2000-06-06 Bowling Green State University Method of treatment of pigmented cancer cells utilizing photodynamic therapy
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AU4278400A (en) 1999-04-14 2000-11-14 University Of British Columbia, The Improved beta,beta,-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins
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Also Published As

Publication number Publication date
JP4976618B2 (ja) 2012-07-18
DE60103697T2 (de) 2005-06-09
EP1164136B1 (de) 2004-06-09
AU2984401A (en) 2001-12-13
CA2342064A1 (en) 2001-12-12
EP1164136A1 (de) 2001-12-19
ATE268777T1 (de) 2004-06-15
JP2002020389A (ja) 2002-01-23
CA2342064C (en) 2011-05-24
US6624187B1 (en) 2003-09-23

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Legal Events

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