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DE60044604D1 - Minimal-invasiver apparat und verfahren zum test zum auffinden von läsionen in der mundhöhle und in ähnlichem epithel - Google Patents

Minimal-invasiver apparat und verfahren zum test zum auffinden von läsionen in der mundhöhle und in ähnlichem epithel

Info

Publication number
DE60044604D1
DE60044604D1 DE60044604T DE60044604T DE60044604D1 DE 60044604 D1 DE60044604 D1 DE 60044604D1 DE 60044604 T DE60044604 T DE 60044604T DE 60044604 T DE60044604 T DE 60044604T DE 60044604 D1 DE60044604 D1 DE 60044604D1
Authority
DE
Germany
Prior art keywords
epithel
similar
minimally invasive
invasive apparatus
cave
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60044604T
Other languages
English (en)
Inventor
Drore Eisen
Stephen Frist
Joel Recht
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CDX LAB Inc
Original Assignee
CDX LAB Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/298,218 external-priority patent/US6284482B1/en
Priority claimed from US09/298,219 external-priority patent/US6297044B1/en
Application filed by CDX LAB Inc filed Critical CDX LAB Inc
Application granted granted Critical
Publication of DE60044604D1 publication Critical patent/DE60044604D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A61B2010/0216—Sampling brushes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1468—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle
    • G01N2015/1472—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle with colour
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1488—Methods for deciding
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/20—Special algorithmic details
    • G06T2207/20084—Artificial neural networks [ANN]
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30024—Cell structures in vitro; Tissue sections in vitro

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Signal Processing (AREA)
  • Quality & Reliability (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Theoretical Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Sewage (AREA)
  • Testing Or Measuring Of Semiconductors Or The Like (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE60044604T 1999-02-23 2000-01-12 Minimal-invasiver apparat und verfahren zum test zum auffinden von läsionen in der mundhöhle und in ähnlichem epithel Expired - Lifetime DE60044604D1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US12125599P 1999-02-23 1999-02-23
US09/298,218 US6284482B1 (en) 1999-04-23 1999-04-23 Method for detection of abnormal keratinization in epithelial tissue
US09/298,219 US6297044B1 (en) 1999-02-23 1999-04-23 Minimally invasive apparatus for testing lesions of the oral cavity and similar epithelium
PCT/US2000/000743 WO2000051066A1 (en) 1999-02-23 2000-01-12 Minimally invasive apparatus and method for testing lesions of the oral cavity and similar epithelium

Publications (1)

Publication Number Publication Date
DE60044604D1 true DE60044604D1 (de) 2010-08-12

Family

ID=27382597

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60044604T Expired - Lifetime DE60044604D1 (de) 1999-02-23 2000-01-12 Minimal-invasiver apparat und verfahren zum test zum auffinden von läsionen in der mundhöhle und in ähnlichem epithel

Country Status (12)

Country Link
US (1) US20020012938A1 (de)
EP (1) EP1155381B1 (de)
JP (1) JP4748628B2 (de)
CN (1) CN100339862C (de)
AT (1) ATE472775T1 (de)
AU (2) AU769471B2 (de)
CA (1) CA2363833C (de)
DE (1) DE60044604D1 (de)
DK (1) DK1155381T3 (de)
IL (2) IL144933A0 (de)
PT (1) PT1155381E (de)
WO (1) WO2000051066A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005064338A1 (en) * 2003-12-23 2005-07-14 University Of Florida Research Foundation, Inc. Microparticles for use in diagnostic methods
US8099600B2 (en) * 2004-08-23 2012-01-17 International Business Machines Corporation Content distribution site spoofing detection and prevention
CA2610294C (en) 2005-05-09 2023-10-03 Theranos, Inc. Point-of-care fluidic systems and uses thereof
JP2007114076A (ja) * 2005-10-21 2007-05-10 Pola Chem Ind Inc 角層細胞の画像の調整方法
WO2011049886A1 (en) * 2009-10-19 2011-04-28 Theranos, Inc. Integrated health data capture and analysis system
CN108369161B (zh) * 2015-11-05 2021-10-01 株式会社资生堂 角质层采集工具和角质层采集检测用试剂盒
CN106570505B (zh) * 2016-11-01 2020-08-21 北京昆仑医云科技有限公司 对组织病理图像进行分析的方法和系统
US12235272B2 (en) 2020-01-13 2025-02-25 New York University Screening and assessment of potentially malignant oral lesions

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2847990A (en) * 1956-03-20 1958-08-19 Ayre James Ernest Instrument for obtaining cells for cytodiagnosis
JPS5615731A (en) * 1979-07-20 1981-02-16 Olympus Optical Co Manufacture of cell diagnosing brush
US5740270A (en) * 1988-04-08 1998-04-14 Neuromedical Systems, Inc. Automated cytological specimen classification system and method
US5623941A (en) * 1988-05-10 1997-04-29 Nils Stormby Cervical sampling velour brush
CA1340245C (en) * 1989-04-21 1998-12-15 John Samuel Monoclonal antibody for differentiation of squamous cell carcinoma antigens and method of use for same
US5257182B1 (en) * 1991-01-29 1996-05-07 Neuromedical Systems Inc Morphological classification system and method
US5184626A (en) * 1991-05-21 1993-02-09 Hicken William J Brush overlay Pap smear
CA2137282A1 (en) * 1992-08-07 1994-02-17 Katherine W. Klinger Process for obtaining a non-liquid cell sample
US5733721A (en) * 1992-11-20 1998-03-31 The Board Of Regents Of The University Of Oklahoma Cell analysis method using quantitative fluorescence image analysis
DE791205T1 (de) * 1994-09-20 1998-10-22 Neopath, Inc., Redmond, Wash. Apparat zum selbstkalibrieren eines biologischen analysesystems
US5713369A (en) * 1995-09-13 1998-02-03 Vance Products Inc. Uterine endometrial tissue sample brush
US6258044B1 (en) * 1998-07-23 2001-07-10 Oralscan/Trylon Joint Venture Apparatus and method for obtaining transepithelial specimen of a body surface using a non-lacerating technique

Also Published As

Publication number Publication date
CN1341244A (zh) 2002-03-20
IL144933A0 (en) 2002-06-30
AU2004201764B8 (en) 2004-05-27
AU2004201764A1 (en) 2004-05-27
DK1155381T3 (da) 2010-11-01
WO2000051066A1 (en) 2000-08-31
CA2363833A1 (en) 2000-08-31
AU769471B2 (en) 2004-01-29
EP1155381A1 (de) 2001-11-21
IL144933A (en) 2006-07-05
CN100339862C (zh) 2007-09-26
AU2004201764B2 (en) 2007-11-22
EP1155381B1 (de) 2010-06-30
JP4748628B2 (ja) 2011-08-17
EP1155381A4 (de) 2006-01-04
CA2363833C (en) 2007-04-03
ATE472775T1 (de) 2010-07-15
PT1155381E (pt) 2010-10-11
AU2412000A (en) 2000-09-14
US20020012938A1 (en) 2002-01-31
JP2002538441A (ja) 2002-11-12

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