DE60031504D1 - Fluticasonpropionat arzneizubereitung - Google Patents
Fluticasonpropionat arzneizubereitungInfo
- Publication number
- DE60031504D1 DE60031504D1 DE60031504T DE60031504T DE60031504D1 DE 60031504 D1 DE60031504 D1 DE 60031504D1 DE 60031504 T DE60031504 T DE 60031504T DE 60031504 T DE60031504 T DE 60031504T DE 60031504 D1 DE60031504 D1 DE 60031504D1
- Authority
- DE
- Germany
- Prior art keywords
- fluticasonpropionate
- drug preparation
- formulation
- fluticasone propionate
- hydrofluoroalkane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 238000009472 formulation Methods 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 229960000289 fluticasone propionate Drugs 0.000 abstract 2
- WMWTYOKRWGGJOA-CENSZEJFSA-N fluticasone propionate Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@@H](C)[C@@](C(=O)SCF)(OC(=O)CC)[C@@]2(C)C[C@@H]1O WMWTYOKRWGGJOA-CENSZEJFSA-N 0.000 abstract 2
- 150000005828 hydrofluoroalkanes Chemical class 0.000 abstract 2
- 239000008249 pharmaceutical aerosol Substances 0.000 abstract 1
- 239000003380 propellant Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9921396 | 1999-09-11 | ||
| GBGB9921396.9A GB9921396D0 (en) | 1999-09-11 | 1999-09-11 | Pharmaceutical formulation |
| GB0014451A GB0014451D0 (en) | 2000-06-13 | 2000-06-13 | Pharmaceutical formulation |
| GB0014451 | 2000-06-13 | ||
| GB0018654A GB0018654D0 (en) | 2000-07-28 | 2000-07-28 | Pharmaceutical formulation |
| GB0018654 | 2000-07-28 | ||
| PCT/GB2000/003471 WO2001019342A2 (en) | 1999-09-11 | 2000-09-11 | Pharmaceutical formulation of fluticasone propionate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60031504D1 true DE60031504D1 (de) | 2006-12-07 |
| DE60031504T2 DE60031504T2 (de) | 2007-04-05 |
Family
ID=27255761
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60031504T Expired - Lifetime DE60031504T2 (de) | 1999-09-11 | 2000-09-11 | Fluticasonpropionat arzneizubereitung |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US6479035B1 (de) |
| EP (1) | EP1143930B8 (de) |
| JP (1) | JP2003509359A (de) |
| AT (1) | ATE343374T1 (de) |
| AU (1) | AU7026800A (de) |
| CA (1) | CA2317999C (de) |
| DE (1) | DE60031504T2 (de) |
| ES (1) | ES2274803T3 (de) |
| FR (4) | FR2798290B1 (de) |
| GB (1) | GB2354007B (de) |
| IT (1) | IT1317904B1 (de) |
| WO (1) | WO2001019342A2 (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9814717D0 (en) * | 1998-02-23 | 1998-09-02 | Bespak Plc | Improvements in drug delivery devices |
| GB2354007B (en) * | 1999-09-11 | 2003-10-22 | Glaxo Group Ltd | Pharmaceutical formulation of fluticasone propionate |
| WO2001047493A1 (en) * | 1999-12-24 | 2001-07-05 | Glaxo Group Limited | Pharmaceutical aerosol formulation of salmeterol and fluticasone propionate |
| IT1317720B1 (it) * | 2000-01-07 | 2003-07-15 | Chiesi Farma Spa | Dispositivo per la somministrazione di aerosol dosati pressurizzati inpropellenti idrofluoroalcani. |
| US6667344B2 (en) | 2001-04-17 | 2003-12-23 | Dey, L.P. | Bronchodilating compositions and methods |
| JP5082033B2 (ja) | 2001-12-21 | 2012-11-28 | エグゼリクシス パテント カンパニー エルエルシー | Lxrのモジュレーター |
| EP1321159A1 (de) * | 2001-12-21 | 2003-06-25 | CHIESI FARMACEUTICI S.p.A. | Betätigungsvorrichtung für Druckdosierinhalator mit lasergebohrten Löchern |
| US7482366B2 (en) | 2001-12-21 | 2009-01-27 | X-Ceptor Therapeutics, Inc. | Modulators of LXR |
| PT3494995T (pt) * | 2002-03-01 | 2020-03-30 | Chiesi Farm Spa | Formulação superfina de formoterol |
| EP1340492A1 (de) * | 2002-03-01 | 2003-09-03 | CHIESI FARMACEUTICI S.p.A. | Aerosolformulierungen zur pulmonalen Verabreichung von Arzneimitteln mit systemischer Wirkung |
| US20040265238A1 (en) * | 2003-06-27 | 2004-12-30 | Imtiaz Chaudry | Inhalable formulations for treating pulmonary hypertension and methods of using same |
| TWI359675B (en) | 2003-07-10 | 2012-03-11 | Dey L P | Bronchodilating β-agonist compositions |
| US8367734B1 (en) | 2005-08-11 | 2013-02-05 | Amphastar Pharmaceuticals Inc. | Stable epinephrine suspension formulation with high inhalation delivery efficiency |
| WO2007064932A2 (en) * | 2005-12-02 | 2007-06-07 | Bayer Healthcare Llc. | Pyrrolotriazine derivatives useful for treating cancer through inhibition of aurora kinase |
| GB0712454D0 (en) * | 2007-06-27 | 2007-08-08 | Generics Uk Ltd | Pharmaceutical compositions |
| EP3403654B1 (de) | 2009-10-01 | 2019-07-31 | Adare Development I, L.P. | Oral verabreichte corticosteroid-zusammensetzungen |
| TWI399202B (zh) | 2011-03-17 | 2013-06-21 | Intech Biopharm Ltd | 製備用於治療呼吸道疾病之定量噴霧吸入劑的製程方法 |
| GB201108039D0 (en) * | 2011-05-13 | 2011-06-29 | Mexichem Amanco Holding Sa | Compositions |
| CN102379846B (zh) * | 2011-10-21 | 2014-07-02 | 江苏长风药业有限公司 | 以氢氟烷烃和聚乙二醇为辅料氟替卡松丙酸酯气雾剂制剂 |
| ES2727474T3 (es) | 2012-05-08 | 2019-10-16 | Nicox Ophthalmics Inc | Nanocristales de propionato de fluticasona |
| US8765725B2 (en) | 2012-05-08 | 2014-07-01 | Aciex Therapeutics, Inc. | Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof |
| US9815865B2 (en) | 2013-01-07 | 2017-11-14 | Nicox Ophthalmics, Inc. | Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof |
| WO2015034678A2 (en) | 2013-09-06 | 2015-03-12 | Aptalis Pharmatech, Inc. | Corticosteroid containing orally disintegrating tablet compositions for eosinophilic esophagitis |
| TWI777515B (zh) | 2016-08-18 | 2022-09-11 | 美商愛戴爾製藥股份有限公司 | 治療嗜伊紅性食道炎之方法 |
| EP3797964B1 (de) | 2019-09-26 | 2023-06-07 | Presspart Manufacturing S.A. | Spritzgiesswerkzeug für inhalator abgemessener dosen |
| WO2021216779A1 (en) * | 2020-04-21 | 2021-10-28 | Amphastar Pharmaceuticals, Inc. | Anti-viral pharmaceutical formulations administered via devices for lung targeted delivery |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE629985A (de) * | 1962-11-29 | |||
| CH634480A5 (de) * | 1977-11-25 | 1983-02-15 | Schwarzkopf Gmbh Hans | Unter druck stehendes aerosolpraeparat. |
| DE2949933A1 (de) | 1979-12-12 | 1981-06-19 | Wabco Fahrzeugbremsen Gmbh, 3000 Hannover | Vorrichtung zum verhindern von schlingerbewegungen eines anhaengers |
| GB8828477D0 (en) * | 1988-12-06 | 1989-01-05 | Riker Laboratories Inc | Medical aerosol formulations |
| IL95590A (en) | 1989-09-08 | 1996-06-18 | Glaxo Group Ltd | Medicinal preparations containing Salmetrol and Pluticasone Propionate |
| GB2235627B (en) | 1989-09-08 | 1993-09-01 | Glaxo Group Ltd | Inhalation medicaments for treating respiratory disorders |
| US5270305A (en) * | 1989-09-08 | 1993-12-14 | Glaxo Group Limited | Medicaments |
| US5919827A (en) | 1990-07-11 | 1999-07-06 | Sepracor Inc. | Method for treating asthma using optically pure R(-) salmeterol |
| WO1992006675A1 (en) | 1990-10-18 | 1992-04-30 | Minnesota Mining And Manufacturing Company | Aerosol formulation comprising beclomethasone 17,21 dipropionate |
| MX9203481A (es) * | 1990-10-18 | 1992-07-01 | Minnesota Mining & Mfg | Formulaciones. |
| US5736124A (en) * | 1991-12-12 | 1998-04-07 | Glaxo Group Limited | Aerosol formulations containing P134a and particulate medicament |
| DK0616525T3 (da) | 1991-12-12 | 1996-01-08 | Glaxo Group Ltd | Medikamenter |
| US5658549A (en) * | 1991-12-12 | 1997-08-19 | Glaxo Group Limited | Aerosol formulations containing propellant 134a and fluticasone propionate |
| US5683676A (en) | 1991-12-12 | 1997-11-04 | Glaxo Group Limited | Canister containing aerosol formulations containing P134a and particulate medicaments |
| IL104068A (en) * | 1991-12-12 | 1998-10-30 | Glaxo Group Ltd | Surfactant-free pharmaceutical aerosol formulation comprising 1,1,1,2-tetrafluoroethane or 1,1,1,2,3,3,3-heptafluoro-n- propane as propellant |
| ES2129117T3 (es) | 1992-12-09 | 1999-06-01 | Boehringer Ingelheim Pharma | Formulaciones en disolucion en forma de aerosol medicinales estabilizadas. |
| GB9313650D0 (en) * | 1993-07-01 | 1993-08-18 | Glaxo Group Ltd | Method and apparatus for the formation of particles |
| DE4446891A1 (de) * | 1994-12-27 | 1996-07-04 | Falk Pharma Gmbh | Stabile wäßrige Budesonid-Lösung |
| AP960A (en) | 1995-04-14 | 2001-04-20 | Glaxo Wellcome Inc | Metered dose inhaler for fluticasone propionate. |
| NZ336049A (en) * | 1996-12-04 | 2000-09-29 | Bioglan Ireland R & D Ltd | Aersol device for administering pharmaceutical active agents in a solution of propellant, carrier and valve means for delivering this to the exterior of the container |
| DK1014943T3 (da) * | 1997-02-05 | 2002-10-14 | Jago Res Ag | Medicinske aerosolformuleringer |
| GB2326334A (en) | 1997-06-13 | 1998-12-23 | Chiesi Farma Spa | Pharmaceutical aerosol compositions |
| US6309623B1 (en) * | 1997-09-29 | 2001-10-30 | Inhale Therapeutic Systems, Inc. | Stabilized preparations for use in metered dose inhalers |
| GB2332372B (en) * | 1997-12-08 | 2002-08-14 | Minnesota Mining & Mfg | Pharmaceutical aerosol compositions |
| KR20010072581A (ko) | 1998-04-30 | 2001-07-31 | 캐롤린 에이. 베이츠 | 약품 에어로졸용 복용량 계량형 밸브 |
| ATE253896T1 (de) | 1998-06-18 | 2003-11-15 | Boehringer Ingelheim Pharma | Zwei oder mehrere wirkstoffe enthaltende pharmazeutische aerosolformulierungen |
| US6241969B1 (en) * | 1998-06-26 | 2001-06-05 | Elan Corporation Plc | Aqueous compositions containing corticosteroids for nasal and pulmonary delivery |
| US6585958B1 (en) * | 1998-07-24 | 2003-07-01 | Jago Research Ag | Medicinal aerosol formulations |
| IT1303788B1 (it) | 1998-11-25 | 2001-02-23 | Chiesi Farma Spa | Formulazioni di aerosol medicinali. |
| US6004537A (en) | 1998-12-18 | 1999-12-21 | Baker Norton Pharmaceuticals, Inc. | Pharmaceutical solution aerosol formulations containing fluoroalkanes, budesonide and formoterol |
| GB9903759D0 (en) | 1999-02-18 | 1999-04-14 | Novartis Ag | Organic compounds |
| US6231519B1 (en) * | 1999-05-04 | 2001-05-15 | Nokia Corporation | Method and apparatus for providing air quality analysis based on human reactions and clustering methods |
| US6315985B1 (en) * | 1999-06-18 | 2001-11-13 | 3M Innovative Properties Company | C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability |
| GB2354007B (en) * | 1999-09-11 | 2003-10-22 | Glaxo Group Ltd | Pharmaceutical formulation of fluticasone propionate |
| ATE286716T1 (de) | 1999-11-23 | 2005-01-15 | Glaxo Group Ltd | Pharmazeutische formulierungen enthaltend salmeterol |
| GB0002798D0 (en) | 2000-02-09 | 2000-03-29 | Glaxo Group Ltd | Actuator nozzle for metered dose inhaler |
-
2000
- 2000-09-11 GB GB0022222A patent/GB2354007B/en not_active Expired - Fee Related
- 2000-09-11 JP JP2001522977A patent/JP2003509359A/ja active Pending
- 2000-09-11 CA CA002317999A patent/CA2317999C/en not_active Expired - Fee Related
- 2000-09-11 DE DE60031504T patent/DE60031504T2/de not_active Expired - Lifetime
- 2000-09-11 EP EP00958854A patent/EP1143930B8/de not_active Revoked
- 2000-09-11 FR FR0011547A patent/FR2798290B1/fr not_active Expired - Fee Related
- 2000-09-11 AU AU70268/00A patent/AU7026800A/en not_active Abandoned
- 2000-09-11 ES ES00958854T patent/ES2274803T3/es not_active Expired - Lifetime
- 2000-09-11 AT AT00958854T patent/ATE343374T1/de not_active IP Right Cessation
- 2000-09-11 US US09/659,492 patent/US6479035B1/en not_active Expired - Fee Related
- 2000-09-11 IT IT2000RM000491A patent/IT1317904B1/it active
- 2000-09-11 WO PCT/GB2000/003471 patent/WO2001019342A2/en not_active Ceased
-
2002
- 2002-03-05 FR FR0202756A patent/FR2820322B1/fr not_active Expired - Fee Related
- 2002-07-19 US US10/198,364 patent/US6630129B2/en not_active Expired - Fee Related
-
2003
- 2003-07-31 US US10/630,655 patent/US7220403B2/en not_active Expired - Fee Related
- 2003-08-04 FR FR0309598A patent/FR2843882B1/fr not_active Expired - Fee Related
-
2004
- 2004-01-21 FR FR0400541A patent/FR2848453B1/fr not_active Expired - Fee Related
- 2004-02-10 US US10/774,393 patent/US20040157815A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ITRM20000491A0 (it) | 2000-09-11 |
| GB0022222D0 (en) | 2000-10-25 |
| CA2317999C (en) | 2004-11-09 |
| US6630129B2 (en) | 2003-10-07 |
| ATE343374T1 (de) | 2006-11-15 |
| EP1143930A3 (de) | 2002-09-11 |
| GB2354007A (en) | 2001-03-14 |
| US6479035B1 (en) | 2002-11-12 |
| AU7026800A (en) | 2001-04-17 |
| FR2848453A1 (fr) | 2004-06-18 |
| US20040157815A1 (en) | 2004-08-12 |
| FR2820322A1 (fr) | 2002-08-09 |
| FR2798290B1 (fr) | 2003-09-12 |
| FR2820322B1 (fr) | 2005-03-11 |
| GB2354007B (en) | 2003-10-22 |
| US7220403B2 (en) | 2007-05-22 |
| IT1317904B1 (it) | 2003-07-15 |
| WO2001019342A2 (en) | 2001-03-22 |
| WO2001019342A3 (en) | 2001-08-09 |
| DE60031504T2 (de) | 2007-04-05 |
| FR2843882A1 (fr) | 2004-03-05 |
| US20040037783A1 (en) | 2004-02-26 |
| ITRM20000491A1 (it) | 2002-03-11 |
| FR2848453B1 (fr) | 2010-09-03 |
| FR2798290A1 (fr) | 2001-03-16 |
| EP1143930A2 (de) | 2001-10-17 |
| EP1143930B1 (de) | 2006-10-25 |
| FR2843882B1 (fr) | 2011-04-22 |
| ES2274803T3 (es) | 2007-06-01 |
| CA2317999A1 (en) | 2001-03-11 |
| US20030086876A1 (en) | 2003-05-08 |
| JP2003509359A (ja) | 2003-03-11 |
| EP1143930B8 (de) | 2008-03-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8363 | Opposition against the patent |