DE60029942D1 - Verwendung von glukose-6-phosphate-isomerase und dagegen gerichteten antikörpern zur diagnose und therapeutischen behandlung von arthritis, und test von zur behandlung der arthritis wirksamen verbindungen - Google Patents
Verwendung von glukose-6-phosphate-isomerase und dagegen gerichteten antikörpern zur diagnose und therapeutischen behandlung von arthritis, und test von zur behandlung der arthritis wirksamen verbindungenInfo
- Publication number
- DE60029942D1 DE60029942D1 DE60029942T DE60029942T DE60029942D1 DE 60029942 D1 DE60029942 D1 DE 60029942D1 DE 60029942 T DE60029942 T DE 60029942T DE 60029942 T DE60029942 T DE 60029942T DE 60029942 D1 DE60029942 D1 DE 60029942D1
- Authority
- DE
- Germany
- Prior art keywords
- arthritis
- treatment
- diagnosis
- glucose
- isomerase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 206010003246 arthritis Diseases 0.000 title abstract 5
- 238000011282 treatment Methods 0.000 title abstract 4
- 102000005731 Glucose-6-phosphate isomerase Human genes 0.000 title abstract 3
- 108010070600 Glucose-6-phosphate isomerase Proteins 0.000 title abstract 3
- 238000003745 diagnosis Methods 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title 1
- 238000000034 method Methods 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 230000002456 anti-arthritic effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- General Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Rehabilitation Therapy (AREA)
- Pathology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Enzymes And Modification Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13073099P | 1999-04-22 | 1999-04-22 | |
| US130730P | 1999-04-22 | ||
| PCT/IB2000/000600 WO2000064469A2 (en) | 1999-04-22 | 2000-04-21 | Use of glucose-6-phospate isomerase and antibodies thereto for the diagnosis and therapy of arthritis, and test of anti-arthritic compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60029942D1 true DE60029942D1 (de) | 2006-09-21 |
| DE60029942T2 DE60029942T2 (de) | 2007-03-08 |
Family
ID=22446051
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60029942T Expired - Lifetime DE60029942T2 (de) | 1999-04-22 | 2000-04-21 | Verwendung von glukose-6-phosphat-isomerase und dagegen gerichtete antikörper zur diagnose und therapeutischen behandlung von arthritis und test von zur behandlung der arthritis-wirksamen verbindungen |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1171157B1 (de) |
| JP (2) | JP4633265B2 (de) |
| AT (1) | ATE335502T1 (de) |
| CA (1) | CA2370867C (de) |
| DE (1) | DE60029942T2 (de) |
| DK (1) | DK1171157T3 (de) |
| ES (1) | ES2269127T3 (de) |
| WO (1) | WO2000064469A2 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020146753A1 (en) * | 2001-04-06 | 2002-10-10 | Henrik Ditzel | Autoantibodies to glucose-6-phosphate isomerase and their participation in autoimmune disease |
| US7973016B2 (en) | 2004-01-23 | 2011-07-05 | Joslin Diebetes Center | Methods of treating, reducing, or preventing autoimmune conditions |
| WO2005115134A1 (ja) * | 2004-05-31 | 2005-12-08 | Japan Science And Technology Agency | レストレスレッグス症候群・周期性四肢運動障害モデル動物 |
| CN105223356A (zh) * | 2015-10-20 | 2016-01-06 | 常州英赞美科生物科技有限公司 | Gpi胶乳增强免疫比浊法体外定量测定诊断试剂盒 |
| WO2025073856A1 (en) | 2023-10-04 | 2025-04-10 | Xenothera | Combination of antibodies, or antigen-binding fragments thereof, for the treatment of cancers |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0720885B2 (ja) * | 1985-09-27 | 1995-03-08 | 帝人株式会社 | 単純ヘルペスウイルス感染症の予防又は治療剤 |
| US5675060A (en) * | 1994-05-19 | 1997-10-07 | Institut National De La Sante Et De La Recherche Medicale | Transgenic arthritic mice expressing a T-cell receptor transgene |
| JPH08245397A (ja) * | 1995-01-13 | 1996-09-24 | Ajinomoto Co Inc | グルコース−６−リン酸イソメラーゼ阻害剤からなる自己分泌型運動因子活性阻害剤 |
| US5977311A (en) * | 1997-09-23 | 1999-11-02 | Curagen Corporation | 53BP2 complexes |
| EP1019080A2 (de) * | 1997-10-02 | 2000-07-19 | Leukosite, Inc. | Modulierung von durch lerk-2 vermittelten zelladhäsionen |
| AUPP589398A0 (en) * | 1998-09-14 | 1998-10-08 | Walter And Eliza Hall Institute Of Medical Research, The | Immunogenic compositions and uses thereof |
-
2000
- 2000-04-21 DK DK00920987T patent/DK1171157T3/da active
- 2000-04-21 ES ES00920987T patent/ES2269127T3/es not_active Expired - Lifetime
- 2000-04-21 EP EP00920987A patent/EP1171157B1/de not_active Expired - Lifetime
- 2000-04-21 CA CA2370867A patent/CA2370867C/en not_active Expired - Lifetime
- 2000-04-21 JP JP2000613459A patent/JP4633265B2/ja not_active Expired - Fee Related
- 2000-04-21 DE DE60029942T patent/DE60029942T2/de not_active Expired - Lifetime
- 2000-04-21 WO PCT/IB2000/000600 patent/WO2000064469A2/en not_active Ceased
- 2000-04-21 AT AT00920987T patent/ATE335502T1/de active
-
2010
- 2010-05-06 JP JP2010106680A patent/JP5231477B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES2269127T3 (es) | 2007-04-01 |
| EP1171157B1 (de) | 2006-08-09 |
| CA2370867A1 (en) | 2000-11-02 |
| DK1171157T3 (da) | 2006-10-30 |
| JP4633265B2 (ja) | 2011-02-16 |
| ATE335502T1 (de) | 2006-09-15 |
| JP2010252795A (ja) | 2010-11-11 |
| WO2000064469A3 (en) | 2001-05-25 |
| DE60029942T2 (de) | 2007-03-08 |
| CA2370867C (en) | 2011-12-06 |
| JP5231477B2 (ja) | 2013-07-10 |
| WO2000064469A2 (en) | 2000-11-02 |
| JP2002544474A (ja) | 2002-12-24 |
| EP1171157A2 (de) | 2002-01-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69926731D1 (de) | Diagnose und behandlung von aur1 und/oder aur2 verwandten erkrankungen | |
| DE69635740D1 (de) | Diagnose und behandlung von mit aur-1 und/oder aur-2 assoziierten erkrankungen | |
| HUP0202532A2 (hu) | Ko-stimulátor szignál-transzdukciós molekula (AILIM) elleni humán monoklonális antitest és gyógyászati alkalmazása | |
| ATE347565T1 (de) | Bispezifischer antikörper zur effektiven behandlung von b-zell lymphomen und zellinien | |
| EA200000298A1 (ru) | Агонисты простагландинов и их применение для лечения заболеваний костей | |
| DE69633717D1 (de) | Monoklonale anti-cd6 antikörper zur behandlung und diagnose von psoriasis | |
| ATE480251T1 (de) | Diagnose und behandlung von malignen neoplasmen | |
| DE60019321D1 (de) | Verfahren zum screening von inhibitoren von asp2 | |
| CA2239208A1 (en) | Treatment and diagnosis of infections due to helicobacter pylori | |
| DE69333076D1 (de) | Test und behandlung von demyelinierenden krankheiten wie multiple sklerosis | |
| ATE166230T1 (de) | Verwendung von anti-icam antikörpern zur herstellung eines präparats für die behandlung von endotoxinschock | |
| BRPI0513135A (pt) | bibliotecas de polinucleotìdeos, método de produção das mesmas, método de identificação de um polinucleotìdeo, região de ligação, meio adequado para uso em um, dispositivo eletrÈnico e dispositivo | |
| DK0948604T3 (da) | Screeningsmetoder for forbindelser som binder til PYK2-polypeptidet | |
| EP1977234A4 (de) | Moleküle zur behandlung von lungenerkrankungen mit einer immunreaktion mit verbindungsgewebe in der lunge | |
| DE69934324D1 (de) | Behandlung von entzündungskrankheiten | |
| DE60029942D1 (de) | Verwendung von glukose-6-phosphate-isomerase und dagegen gerichteten antikörpern zur diagnose und therapeutischen behandlung von arthritis, und test von zur behandlung der arthritis wirksamen verbindungen | |
| Kirkham et al. | Growth arrest of γδ T cells induced by monoclonal antibody against WC1 correlates with activation of multiple tyrosine phosphatases and dephosphorylation of MAP kinase erk2 | |
| DE69615843D1 (de) | Il-8 antagonisten zur behandlung von asthma | |
| EP1254260A4 (de) | Methoden zur diagnose und behandlung von herzkrankheiten | |
| ATE354095T1 (de) | Verfahren zur detektion von prp unter verwendung ein makrozyklischen ligand | |
| ATE186553T1 (de) | Competitives enzym-testverfahren zum nachweis von phosphothioaten | |
| ATE293994T1 (de) | Multivalente rekombinante antikörper zur behandlung von hrv infektionen | |
| FI980748A0 (fi) | Foerfarande foer bestaemning av resorptionshastigheten i ben | |
| DE60127935D1 (de) | Verfahren zur diagnose der effektivität der xenotypischen antikörpertherapie | |
| ATE312914T1 (de) | Rdgb-proteine |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |